Xiangli Zeng
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View article: MLL1 downregulation drives hair cell ferroptosis via mitochondrial and endoplasmic reticulum stress mechanisms through PERK–eIF2α–Atf4–Chop and PI3K/Akt–Lrp1 signaling pathway
MLL1 downregulation drives hair cell ferroptosis via mitochondrial and endoplasmic reticulum stress mechanisms through PERK–eIF2α–Atf4–Chop and PI3K/Akt–Lrp1 signaling pathway Open
Background: Sensorineural hearing loss is characterized by irreversible hair cell (HC) degeneration. Ferroptosis, which is marked by the accumulation of reactive oxygen species and elevated levels of lipid peroxidation products, has been s…
View article: Size effect and phenomenological constitutive model of mechanical properties of ultra-thin 316L sheet
Size effect and phenomenological constitutive model of mechanical properties of ultra-thin 316L sheet Open
To further enhance the fuel cell stack efficiency and reduce weight, the thickness of stainless steel bipolar plates is showing a decreasing trend, and the thickness of 0.075 mm is being considered. In this paper, 316L stainless steel with…
View article: [A retrospective analysis of the clinical characteristics of 63 patients with vestibular neuritis].
[A retrospective analysis of the clinical characteristics of 63 patients with vestibular neuritis]. Open
Objective:To retrospectively analyze the results of auditory examination,vestibular function examination and laboratory examination of 63 patients diagnosed as vestibular neuritis.Methods:A total of 63 patients diagnosed with vestib…
View article: A Quantitative Ultrasonic Detection Method for Mannitol Concentration Based on a Capacitive Micromachined Ultrasonic Transducer
A Quantitative Ultrasonic Detection Method for Mannitol Concentration Based on a Capacitive Micromachined Ultrasonic Transducer Open
View article: [Association between sleep disorders and vestibular vertigo].
[Association between sleep disorders and vestibular vertigo]. Open
Sleep disorders have a high comorbidity rate with vestibular diseases. The results of some small sample clinical studies have confirmed the effect of sleep deprivation on vestibular function. However, the mechanism of the effect of…
View article: Triple semicircular canal occlusion with endolymphatic sac decompression for intractable Meniere’s disease
Triple semicircular canal occlusion with endolymphatic sac decompression for intractable Meniere’s disease Open
Background Meniere’s disease (MD) is characterized by idiopathic endolymphatic hydrops (ELH). Frequent vertigo attacks is the most disabling symptom of MD. Objective This study evaluated the efficacy of triple semicircular canal occlusion …
View article: The Impact of Sleep Quality on Cognitive Function in Patients with Chronic Subjective Tinnitus
The Impact of Sleep Quality on Cognitive Function in Patients with Chronic Subjective Tinnitus Open
BACKGROUND: The aim of this study was to explore the impact of sleep quality on cognitive function in patients with chronic subjective tinnitus. METHODS: The Pittsburgh Sleep Quality Index (PSQI) and the Montreal Cognitive Assessment Scale…
View article: Newborn Screening for Congenital Hearing Impairment: A 17-Year Experience for Improving Quality of Healthcare
Newborn Screening for Congenital Hearing Impairment: A 17-Year Experience for Improving Quality of Healthcare Open
Background: To improve healthcare quality, a preventive intervention system has been developed globally with routine newborn screening, diagnosis, intervention, and rehabilitation for congenital hearing impairment. An intervention program …
View article: Personality Traits and Tinnitus Distress
Personality Traits and Tinnitus Distress Open
Background: Due to the socio-cultural differences between China and other countries, which may affect the development of an individual’s personality and behavior, it is necessary to explore the relationship between personality traits and t…
View article: Analysis of the Efficacy and Safety of Intratymapanic Dexamethasone for Treating Meniere’s Disease: A Randomized Controlled Trial
Analysis of the Efficacy and Safety of Intratymapanic Dexamethasone for Treating Meniere’s Disease: A Randomized Controlled Trial Open
Objectives Our objective was to study the efficacy and safety of intratymapanic dexamethasone (ITD) for treating in Méniere’s disease in southern China. Methods A total of 124 patients with Méniere’s disease were randomly divided into 2 gr…
View article: [An analyzation on the characterization of frequency tuning of vestibular evoked myogenic potential in patients with unilateral vestibular hypofunction].
[An analyzation on the characterization of frequency tuning of vestibular evoked myogenic potential in patients with unilateral vestibular hypofunction]. Open
Objective: To explore the value of adding 1 kHz cervical vestibular evoked myogenic potential（cVEMP） and ocular vestibular evoked myogenic potential（oVEMP） in the auxiliary diagnosis of unilateral vestibular hypofunction. Methods…
View article: Analysis of Studies in Tinnitus-Related Gene Research
Analysis of Studies in Tinnitus-Related Gene Research Open
Objective: Summarize and analyze the current research results of tinnitus-related genes, explore the potential links between the results of each study, and provide reference for subsequent studies. Methods: Collect and sort out the researc…
View article: Standardization of calibration scheme in NB Chirp ABR Hearing Assessment: A Preliminary Study Based on Normal Hearing Soldiers
Standardization of calibration scheme in NB Chirp ABR Hearing Assessment: A Preliminary Study Based on Normal Hearing Soldiers Open
Background: Optimal medical intervention for veterans suffering from military noise-induced hearing impairment is a major concern of the specialists in military medicine, otology, and audiology sectors. Thus, it is important to objectively…
View article: Acute exacerbation of chronic subjective tinnitus: a cross-sectional study
Acute exacerbation of chronic subjective tinnitus: a cross-sectional study Open
To the editor: Tinnitus is the impression of sounds in the absence of external sounds. Tinnitus affects 10% to 15% of adults, and about 20% of those with tinnitus considered it bothersome.[1] The impact of tinnitus is well-recognized in th…
View article: [Efficacy of percutaneous vagal stimulation in the treatment of chronic tinnitus].
[Efficacy of percutaneous vagal stimulation in the treatment of chronic tinnitus]. Open
Objective:The aim of this study is to investigate the efficacy of transcutaneous vagus nerve stimulation（taVNS） in the treatment of chronic tinnitus. Methods:taVNS was used to treat chronic decompensated tinnitus, 10 days as …
View article: Impacts of different methylprednisolone administration routes in patients with sudden hearing loss or Meniere’s disease
Impacts of different methylprednisolone administration routes in patients with sudden hearing loss or Meniere’s disease Open
These findings suggest that systemic glucocorticoid administration can result in greater whole body responses than local administration, but with similar hearing treatment efficacy.
View article: Analysis of the characteristics of rare complications after tympanic injection in south China: a randomized controlled trial
Analysis of the characteristics of rare complications after tympanic injection in south China: a randomized controlled trial Open
Objectives: To study the complications of intratymapanic dexamethasone for Méniere’s disease. Study Design:a randomized controlled trial. Methods:124 patients with Méniere’s disease were randomly divided into two groups: Intratympanic dexa…
View article: Acute Exacerbation of Chronic Subjective Tinnitus: a Cross-sectional Study
Acute Exacerbation of Chronic Subjective Tinnitus: a Cross-sectional Study Open
Background: To analyze data from the tinnitus study that addresses the factors contributing to the acute exacerbation of chronic subjective tinnitus, and providing a comprehensive landscape of multiple factors action patterns on acute exac…
View article: Sudden Hearing Loss and Vertigo Caused by a Transitional Meningioma in Pregnancy
Sudden Hearing Loss and Vertigo Caused by a Transitional Meningioma in Pregnancy Open
View article: Loss of Vision Dominance at the Preresponse Level in Tinnitus Patients: Preliminary Behavioral Evidence
Loss of Vision Dominance at the Preresponse Level in Tinnitus Patients: Preliminary Behavioral Evidence Open
At present, the mechanisms underlying changes in visual processing in individuals with tinnitus remain unclear. Therefore, we investigated whether the vision dominance of individuals with tinnitus disappears at the preresponse level throug…
View article: NLRC5: potential novel non-invasive biomarker for predicting and reflecting the progression of IgA nephritis
NLRC5: potential novel non-invasive biomarker for predicting and reflecting the progression of IgA nephritis Open
View article: Eyes and Ears: Cross-Modal Interference of Tinnitus on Visual Processing
Eyes and Ears: Cross-Modal Interference of Tinnitus on Visual Processing Open
The visual processing capacity of tinnitus patients is worse than normal controls, indicating cross-modal interference. However, the mechanism underlying the tinnitus-modulated visual processing is largely unclear. In order to explore the …
View article: Attentional Bias in Patients with Decompensated Tinnitus: Prima Facie Evidence from Event-Related Potentials
Attentional Bias in Patients with Decompensated Tinnitus: Prima Facie Evidence from Event-Related Potentials Open
Tinnitus refers to the auditory perception of sound in the absence of external sound or electric stimuli. The influence of tinnitus on cognitive processing is at the cutting edge of ongoing tinnitus research. In this study, we adopted an o…
View article: Skin reactions caused by bone-anchored hearing aid (BAHA) implantation
Skin reactions caused by bone-anchored hearing aid (BAHA) implantation Open
Skin adverse reactions, usually rare in BAHA implantation patients, may cause implant removal and implantation failure. We suggest to further investigate the mechanisms underlying titanium allergy.