Xiangfeng Chen
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View article: Investigation on Chiral Amino Acids Enantiomeric Excess With Cyclodextrin Inclusion Complex Ions Assisted Differential Ion Mobility Separation Mass Spectrometry
Investigation on Chiral Amino Acids Enantiomeric Excess With Cyclodextrin Inclusion Complex Ions Assisted Differential Ion Mobility Separation Mass Spectrometry Open
Development of a rapid, inexpensive, and specific method for chiral amino acids (AAs) identification and separation is challenging owing to their similar properties. In this work, a chiral AAs separation method was developed by analyzing t…
View article: Development of Differential Ion Mobility Spectrometry Based Tandem Devices for Ion Separation Prior to Mass Spectrometry Analysis
Development of Differential Ion Mobility Spectrometry Based Tandem Devices for Ion Separation Prior to Mass Spectrometry Analysis Open
Rationale Differential ion mobility spectrometry (DMS) provides distinct potential in separation of gas phase ions. However, the resolving power still limits the widespread application of DMS technology and inspires to design tandem DMS fo…
View article: Astragaloside IV attenuates glucocorticoid-induced osteoclastogenesis and bone loss via the MAPK/NF-κB pathway
Astragaloside IV attenuates glucocorticoid-induced osteoclastogenesis and bone loss via the MAPK/NF-κB pathway Open
This study demonstrates that AS-IV inhibits GIO and attenuates bone loss via the MAPK/NF-κB pathway. This also suggested that AS-IV could be a potential promising therapeutic agent for glucocorticoid-triggered bone loss.
View article: A review on technologies for the removal of per- and polyfluoroalkyl substances (PFASs) in aquatic environments
A review on technologies for the removal of per- and polyfluoroalkyl substances (PFASs) in aquatic environments Open
This review summarizes PFAS removal technologies in aqueous systems and analyzes the efficacy, functional mechanisms, and structure–activity relationships governing each technique.
View article: Structural analysis, anti-inflammatory activity of the main water-soluble acidic polysaccharides (AGBP-A3) from Panax quinquefolius L berry
Structural analysis, anti-inflammatory activity of the main water-soluble acidic polysaccharides (AGBP-A3) from Panax quinquefolius L berry Open
The present study demonstrated the structure of acidic polysaccharides of P. quinquefolius berry and their effect on inflammation, providing a reference for screening anti-inflammatory drugs.
View article: MiRNA‐224‐5p regulates the defective permeability barrier in sensitive skin by targeting claudin‐5
MiRNA‐224‐5p regulates the defective permeability barrier in sensitive skin by targeting claudin‐5 Open
Background Sensitive skin is hypersensitive to various external stimuli and a defective epidermal permeability barrier is an important clinical feature of sensitive skin. Claudin‐5 ( CLDN5 ) expression levels decrease in sensitive skin. Th…
View article: The hidden diet: Synthetic antioxidants in packaged food and their impact on human exposure and health
The hidden diet: Synthetic antioxidants in packaged food and their impact on human exposure and health Open
Synthetic antioxidants (AOs) are commonly used in everyday items and industrial products to inhibit oxidative deterioration. However, the presence of AOs in food packaging and packaged foods has not been thoroughly documented. Moreover, st…
View article: Lactobacillus paracasei ZFM54 alters the metabolomic profiles of yogurt and the co-fermented yogurt improves the gut microecology of human adults
Lactobacillus paracasei ZFM54 alters the metabolomic profiles of yogurt and the co-fermented yogurt improves the gut microecology of human adults Open
Gut microbiota imbalance could lead to various diseases, making it important to optimize the structure of the gut flora in adults. Lactobacillus paracasei ZFM54 is a bacteriocin- and folic acid-producing Lactobacillus strain. Herein, L. pa…
View article: A review of factors influencing sensitive skin: an emphasis on built environment characteristics
A review of factors influencing sensitive skin: an emphasis on built environment characteristics Open
Background Sensitive skin (SS) is a condition characterized by hyperreactivity. Impacting around 37 percent of the worldwide population and exerting an influence on the quality of life for affected individuals. Its prevalence rate has incr…
View article: Current Knowledge of Individual and Combined Toxicities of Aflatoxin B1 and Fumonisin B1 In Vitro
Current Knowledge of Individual and Combined Toxicities of Aflatoxin B1 and Fumonisin B1 In Vitro Open
Mycotoxins are considered the most threating natural contaminants in food. Among these mycotoxins, aflatoxin B1 (AFB1) and fumonisin B1 (FB1) are the most prominent fungal metabolites that represent high food safety risks, due to their wid…
View article: Astragaloside IV attenuates glucocorticoid-induced osteoclastogenesis and bone loss via the MAPK/NF-κB pathway
Astragaloside IV attenuates glucocorticoid-induced osteoclastogenesis and bone loss via the MAPK/NF-κB pathway Open
Background Astragaloside IV (AS-IV) is a bioactive saponin extracted from astragalus membranaceus, and it is reported to promote osteoblast differentiation while inhibiting osteoclastogenesis. However, the mechanism of AS-IV in glucocortic…
View article: Aspergillus flavus and Fusarium verticillioides and Their Main Mycotoxins: Global Distribution and Scenarios of Interactions in Maize
Aspergillus flavus and Fusarium verticillioides and Their Main Mycotoxins: Global Distribution and Scenarios of Interactions in Maize Open
Maize is frequently contaminated with multiple mycotoxins, especially those produced by Aspergillus flavus and Fusarium verticillioides. As mycotoxin contamination is a critical factor that destabilizes global food safety, the current revi…
View article: Author Correction: Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury
Author Correction: Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury Open
The original version of this Article contained an error in the 'The MN-MSC patch alleviates the inflammatory response in spinal cord lesions after SCI' section of the Results, which incorrectly read 'However, only the MN-EV treatment yield…
View article: Understanding the Effect of Grain Boundaries on the Mechanical Properties of Epoxy/Graphene Composites
Understanding the Effect of Grain Boundaries on the Mechanical Properties of Epoxy/Graphene Composites Open
This work presents a molecular dynamics (MD) simulation study on the effect of grain boundaries (GBs) on the mechanical properties of epoxy/graphene composites. Ten types of GB models were constructed and comparisons were made for epoxy/gr…
View article: Provable Routing Analysis of Programmable Photonics
Provable Routing Analysis of Programmable Photonics Open
Programmable photonic integrated circuits (PPICs) are an emerging technology recently proposed as an alternative to custom-designed application-specific integrated photonics. Light routing is one of the most important functions that need t…
View article: Amide-containing neoepitopes: the key factor in the preparation of hapten-specific antibodies and a strategy to overcome
Amide-containing neoepitopes: the key factor in the preparation of hapten-specific antibodies and a strategy to overcome Open
For a long time, people have suffered from uncertainty, complexity, and a low success rate in generating and screening antibodies against small molecules, which have become the core bottlenecks of immunochemistry. Here, the influence of an…