Xiaoling Xu
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View article: Dasatinib Inhibits Basal B Breast Cancer Through ETS1-Mediated Extracellular Matrix Remodeling
Dasatinib Inhibits Basal B Breast Cancer Through ETS1-Mediated Extracellular Matrix Remodeling Open
Background/Objectives: Developing effective therapies for patients with triple-negative breast cancer (TNBC) remains an urgent clinical priority. Compared with other subtypes, the basal B type of TNBC exhibits a less differentiated and mes…
View article: FGF21-engineered ADSCs promote diabetic wound healing by mitigating ferroptosis and oxidative stress via the SIRT1/NRF2/GPX4 signaling pathway
FGF21-engineered ADSCs promote diabetic wound healing by mitigating ferroptosis and oxidative stress via the SIRT1/NRF2/GPX4 signaling pathway Open
View article: Avian diversity patterns across residential neighbourhoods of different development stages: Insights from a subtropical waterfront metropolis in China
Avian diversity patterns across residential neighbourhoods of different development stages: Insights from a subtropical waterfront metropolis in China Open
This study examined bird diversity across 33 residential neighbourhoods in Fuzhou, China, representing different development stages. We found that mid-aged neighbourhoods supported the highest bird diversity and abundance, driven primarily…
View article: Efficacy and Safety of Rb‐bFGF in Hair Transplantation: A Prospective and Comparative Study
Efficacy and Safety of Rb‐bFGF in Hair Transplantation: A Prospective and Comparative Study Open
Objective This prospective randomized controlled trial aimed to evaluate the clinical value of recombinant bovine basic fibroblast growth factor (rb‐bFGF)‐based combined therapy in hair transplantation, focusing on its optimization effects…
View article: A CiteSpace-based Bibliometric Review of Public Health Governance System with the Belt and Road Initiative
A CiteSpace-based Bibliometric Review of Public Health Governance System with the Belt and Road Initiative Open
With the support of CiteSpace, this paper adopts bibliometric analysis to sort out macro concepts of the literature on public health under the Belt and Road Initiative and public health governance. Visual knowledge graphs are drawn in term…
View article: Synthesis and Study of Antioxidant Composite Resistive Materials Based on Anti-Spontaneous Coal Combustion Application
Synthesis and Study of Antioxidant Composite Resistive Materials Based on Anti-Spontaneous Coal Combustion Application Open
View article: Refined Visceral Pleural Invasion Stratification Optimizes Postoperative Adjuvant Therapy Decision-Making in Stage IB Non-Small Cell Lung Cancer: A Multicenter Cohort Analysis
Refined Visceral Pleural Invasion Stratification Optimizes Postoperative Adjuvant Therapy Decision-Making in Stage IB Non-Small Cell Lung Cancer: A Multicenter Cohort Analysis Open
View article: Polydopamine-based Nanoadjuvants Promote a Positive Feedback Loop for Cancer Immunotherapy via Overcoming Photothermally Boosted T Cell Exhaustion
Polydopamine-based Nanoadjuvants Promote a Positive Feedback Loop for Cancer Immunotherapy via Overcoming Photothermally Boosted T Cell Exhaustion Open
Immunogenic cell death, triggered by photothermal therapy or specific chemotherapy, strives to establish a positive feedback loop in cancer immunotherapy. This loop is characterized by the rapid release of antigens and adenosine triphospha…
View article: Associations between Multiple Food Consumption Frequencies and the Incidence of Cardiovascular Disease in High Cardiac Risk Subjects
Associations between Multiple Food Consumption Frequencies and the Incidence of Cardiovascular Disease in High Cardiac Risk Subjects Open
Background: Dietary choices are inextricably linked to the incidence of cardiovascular disease (CVD), whereas an optimal dietary pattern to minimize CVD morbidity in high-risk subjects remains challenging. Methods: We comprehensively asses…
View article: Salicylic acid inhibition on browning of fresh-cut taro by regulating phenolic compounds and active oxygen metabolism
Salicylic acid inhibition on browning of fresh-cut taro by regulating phenolic compounds and active oxygen metabolism Open
Surface browning of fresh-cut taro limits storage shelf-life and affects customer satisfaction. This study investigated the effects of salicylic acid (SA) on the browning of fresh-cut taro and explored the possible mechanism of SA in inhib…
View article: Efficacy of antihypertensive treatment for target organ protection in patients with masked hypertension (ANTI-MASK): a multicentre, double-blind, placebo-controlled trial
Efficacy of antihypertensive treatment for target organ protection in patients with masked hypertension (ANTI-MASK): a multicentre, double-blind, placebo-controlled trial Open
View article: Author Correction: NIPBL-mediated RAD21 facilitates tumorigenicity by the PI3K pathway in non-small-cell lung cancer
Author Correction: NIPBL-mediated RAD21 facilitates tumorigenicity by the PI3K pathway in non-small-cell lung cancer Open
View article: [Effects of cerium oxide nanoenzyme-gelatin methacrylate anhydride hydrogel in the repair of infected full-thickness skin defect wounds in mice].
[Effects of cerium oxide nanoenzyme-gelatin methacrylate anhydride hydrogel in the repair of infected full-thickness skin defect wounds in mice]. Open
Objective: To investigate the effects of cerium oxide nanoenzyme-gelatin methacrylate anhydride (GelMA) hydrogel (hereinafter referred to as composite hydrogel) in the repair of infected full-thickness skin defect wounds in mice.
View article: NIPBL-mediated RAD21 facilitates tumorigenicity by the PI3K pathway in non-small-cell lung cancer
NIPBL-mediated RAD21 facilitates tumorigenicity by the PI3K pathway in non-small-cell lung cancer Open
View article: Sirt6 ablation in the liver causes fatty liver that increases cancer risk by upregulating Serpina12
Sirt6 ablation in the liver causes fatty liver that increases cancer risk by upregulating Serpina12 Open
View article: Impact of different sequential triple oral combination therapies based selexipag on outcomes in pulmonary arterial hypertension
Impact of different sequential triple oral combination therapies based selexipag on outcomes in pulmonary arterial hypertension Open
Background While the GRIPHON study and others have confirmed the efficacy and safety of selexipag with single, dual, and initial triple combination therapy for patients with pulmonary arterial hypertension (PAH), multicenters studies conce…
View article: Case report: SAF-189s is a potent inhibitor in a lorlatinib-resistant NSCLC patient with acquired compound mutations ALK L1196M and D1203N
Case report: SAF-189s is a potent inhibitor in a lorlatinib-resistant NSCLC patient with acquired compound mutations ALK L1196M and D1203N Open
Acquired anaplastic lymphoma kinase (ALK) mutation is the major resistant mechanism to ALK tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) patients. At present, treatment options after acquiring secondary ALK mutati…
View article: Application of tip-bendable ureteral access sheath in flexible ureteroscopic lithotripsy: an initial experience of 224 cases
Application of tip-bendable ureteral access sheath in flexible ureteroscopic lithotripsy: an initial experience of 224 cases Open
View article: Sintilimab plus anlotinib as second‐ or third‐line therapy in metastatic non‐small cell lung cancer with uncommon epidermal growth factor receptor mutations: A prospective, single‐arm, phase II trial
Sintilimab plus anlotinib as second‐ or third‐line therapy in metastatic non‐small cell lung cancer with uncommon epidermal growth factor receptor mutations: A prospective, single‐arm, phase II trial Open
Background Patients with non‐small‐cell lung cancer (NSCLC) and uncommon EGFR alterations typically have worse treatment outcomes than patients with classically EGFR ‐mutated NSCLC. This study aimed to investigate the efficacy and safety o…
View article: Application of tip-bendable ureteral access sheath in flexible ureteroscopic lithotripsy: an initial experience of 224 cases
Application of tip-bendable ureteral access sheath in flexible ureteroscopic lithotripsy: an initial experience of 224 cases Open
Introduction: During the last decades, the advent of flexible ureteroscopic lithotripsy has revolutionized the management of upper urinary tract stones. We designed a patented tip-bendable ureteral access sheath to facilitate stone clearan…
View article: ALK-Positive Adenocarcinoma After Acquired Resistance to Lorlatinib and Transformation to SCLC: A Case Report
ALK-Positive Adenocarcinoma After Acquired Resistance to Lorlatinib and Transformation to SCLC: A Case Report Open
View article: The Efficacy of PD-1/PD-L1 Inhibitors in Patients with Liver Metastasis of Non-Small Cell Lung Cancer: A Real-World Study
The Efficacy of PD-1/PD-L1 Inhibitors in Patients with Liver Metastasis of Non-Small Cell Lung Cancer: A Real-World Study Open
Background: A controversy exists regarding the efficacy of programmed death-1 (PD-1)/ programmed death ligand-1 (PD-L1) inhibitors for patients with non-small cell lung cancer (NSCLC) and liver metastases. Our study retrospectively evaluat…
View article: Tolerability, safety, and preliminary antitumor activity of fuzuloparib in combination with SHR-1316 in patients with relapsed small cell lung cancer: a multicenter, open-label, two-stage, phase Ib trial
Tolerability, safety, and preliminary antitumor activity of fuzuloparib in combination with SHR-1316 in patients with relapsed small cell lung cancer: a multicenter, open-label, two-stage, phase Ib trial Open
Fuzuloparib combined with SHR-1316 failed to improve the outcomes in unselected patients with relapsed SCLC. Future studies with biomarker analysis are warranted to select patients most likely to benefit from this combination treatment. Fu…
View article: Clinical features and prognosis of resectable pulmonary primary invasive mucinous adenocarcinoma
Clinical features and prognosis of resectable pulmonary primary invasive mucinous adenocarcinoma Open
In this study, we found that resectable IMA patients had a better OS than NMA patients. This study contributes to the understanding of IMA in depth, but it needs to be validated through additional multicenter studies.
View article: ASO Author Reflection: The TME-Related Gene AIF1 Signature Predicts Esophageal Carcinoma Prognosis
ASO Author Reflection: The TME-Related Gene AIF1 Signature Predicts Esophageal Carcinoma Prognosis Open
View article: High Efficacy of Recombinant Fusion Protein ESAT6-CFP10 as a Skin Test Reagent for Adult Tuberculosis: A Phase III, Multi-Centered, Double-Blind, Hospital-Based, Randomized Controlled Trial
High Efficacy of Recombinant Fusion Protein ESAT6-CFP10 as a Skin Test Reagent for Adult Tuberculosis: A Phase III, Multi-Centered, Double-Blind, Hospital-Based, Randomized Controlled Trial Open
View article: Secondary bloodstream infection in critically ill patients with COVID-19
Secondary bloodstream infection in critically ill patients with COVID-19 Open
Objective Secondary infection, especially bloodstream infection, is an important cause of death in critically ill patients with COVID-19. We aimed to describe secondary bloodstream infection (SBI) in critically ill adults with COVID-19 in …
View article: A nomogram model based on peripheral blood lymphocyte subsets to assess the prognosis of non-small cell lung cancer patients treated with immune checkpoint inhibitors
A nomogram model based on peripheral blood lymphocyte subsets to assess the prognosis of non-small cell lung cancer patients treated with immune checkpoint inhibitors Open
ICI treatment induced changes in the percentage of peripheral blood lymphocyte subsets, which had prognostic value for brain metastases, radiotherapy, EGFR status, pathology, and therapeutic regimen, along with prognostic value, for NSCLC …
View article: Non-surgical management of an abrupt cavitation and large oval-shaped lung abscess secondary to acute thromboembolic pulmonary infarction: a case report
Non-surgical management of an abrupt cavitation and large oval-shaped lung abscess secondary to acute thromboembolic pulmonary infarction: a case report Open
Infected cavitating pulmonary infarction is a rare complication of pulmonary embolism with a high mortality rate. Surgical excision for this complication has been used in past decades. Abrupt cavitation and a large oval-shaped lung abscess…
View article: Clinical Relevance of PD-L1 Expression and CD8+ T Cells’ Infiltration in Patients With Lung Invasive Mucinous Adenocarcinoma
Clinical Relevance of PD-L1 Expression and CD8+ T Cells’ Infiltration in Patients With Lung Invasive Mucinous Adenocarcinoma Open
Background Invasive mucinous adenocarcinoma (IMA) of the lung is a rare and distinct subtype of adenocarcinoma. At present, people have no idea whether IMA patients can benefit from immunotherapy and target therapy; thus there is an urgent…