Xianglai Jiang
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View article: VTA1 and breast cancer: a potential indicator for diagnostic and prognostic evaluation
VTA1 and breast cancer: a potential indicator for diagnostic and prognostic evaluation Open
Objectives Vacuolar protein sorting-associated protein VTA1 homolog (VTA1) encodes a factor involved in multivesicular body trafficking. This investigation sought to determine if VTA1 might function as a diagnostic indicator, a standalone …
View article: The diagnostic or prognostic values of FADD in cancers based on pan‑cancer analysis
The diagnostic or prognostic values of FADD in cancers based on pan‑cancer analysis Open
Previous studies have determined that aberrant expression of the fas-associated death domain (FADD) contributes to the development of cancer. However, no pan-cancer analysis has been reported to explore the relationship between FADD and va…
View article: Cisplatin promotes pyroptosis of gastric cancer cells by activating GSDME
Cisplatin promotes pyroptosis of gastric cancer cells by activating GSDME Open
According to studies, numerous chemotherapeutic drugs can facilitate programmed cell death via pyroptosis. Clarifying the mechanism by which cisplatin kills gastric cancer cells is crucial for enhancing gastric cancer’s sensitivity to chem…
View article: The machine learning algorithm identified COL7A1 as a diagnostic marker for LUSC and HNSC
The machine learning algorithm identified COL7A1 as a diagnostic marker for LUSC and HNSC Open
Squamous cell carcinomas (SCCs) comes from different parts, but there may be similar tumorigenic signaling pathways and metabolism, and different squamous cell carcinoma has a similar mutation landscape and squamous differentiation express…
View article: Constructing a novel signature and predicting the immune landscape of colon cancer using N6-methylandenosine-related lncRNAs
Constructing a novel signature and predicting the immune landscape of colon cancer using N6-methylandenosine-related lncRNAs Open
Background: Colon cancer (CC) is a prevalent malignant tumor that affects people all around the world. In this study, N6-methylandenosine-related long non-coding RNAs (m6A-related lncRNAs) in 473 colon cancers and 41 adjacent tissues of CC…
View article: Pan-cancer analysis, providing a reliable basis for IDO2 as a prognostic biomarker and target for immunotherapy
Pan-cancer analysis, providing a reliable basis for IDO2 as a prognostic biomarker and target for immunotherapy Open
Objectives Indoleamine 2,3-dioxygenase 2 (IDO2) is a homologous protein of the classical immune negative regulator Indoleamine 2,3-dioxygenase 1 (IDO1) that is indispensable in the metabolism of tryptophan and is closely related to the pat…
View article: A Pan-Cancer Analysis Indicates the Prognostic Significance and Immunological Function of V-Set Domain Containing T-Cell Activation Inhibitor 1
A Pan-Cancer Analysis Indicates the Prognostic Significance and Immunological Function of V-Set Domain Containing T-Cell Activation Inhibitor 1 Open
The immune costimulatory protein V-set domain containing T cell activation inhibitor 1 is a key molecule in the B7 family developing advanced growth in multiple cancers as a suppressive regulatory factor during T cell immunoreaction. For t…
View article: A pan-cancer analysis of the biological function and clinical value of BTLA in tumors
A pan-cancer analysis of the biological function and clinical value of BTLA in tumors Open
B and T-lymphocyte attenuator (BTLA) plays an immunosuppressive role by inhibiting T- and B-cell functions. BTLA is associated with a variety of diseases, especially cancer immunity. However, the function of BTLA in various cancers and its…
View article: PAIP2 is a potential diagnostic and prognostic biomarker of breast cancer and is associated with immune infiltration
PAIP2 is a potential diagnostic and prognostic biomarker of breast cancer and is associated with immune infiltration Open
Breast cancer is the second highest incidence of cancer in the world. It is of great significance to find biomarkers to diagnose breast cancer and predict the prognosis of breast cancer patients. PAIP2 is a poly (A) -binding protein intera…
View article: LncRNA DUXAP8 as a prognostic biomarker for various cancers: A meta-analysis and bioinformatics analysis
LncRNA DUXAP8 as a prognostic biomarker for various cancers: A meta-analysis and bioinformatics analysis Open
Background: Dual homeoboxes A pseudogene 8 ( DUXAP8 ) is a newly discovered long noncoding RNA that has been shown to function as an oncogene in a variety of human malignant cancers. By integrating available data, this meta-analysis sought…
View article: Clinicopathological Significance and Prognostic Values of Long Noncoding RNA BCYRN1 in Cancer Patients: A Meta-Analysis and Bioinformatics Analysis
Clinicopathological Significance and Prognostic Values of Long Noncoding RNA BCYRN1 in Cancer Patients: A Meta-Analysis and Bioinformatics Analysis Open
Background. Although combination therapies have substantially improved the clinical outcomes of cancer patients, the prognosis and early diagnosis remain unsatisfactory. As a result, it is critical to look for novel indicators linked to ca…
View article: Constructing a Novel Signature and Predicting the Immune Landscape of Colon Cancer Using N6-Methylandenosine-Related lncRNAs
Constructing a Novel Signature and Predicting the Immune Landscape of Colon Cancer Using N6-Methylandenosine-Related lncRNAs Open
Background: Colon cancer (CC) is a prevalent malignant tumor that affects people all around the world. In this study, N6-methylandenosine-related long non-coding RNAs (m6A- related lncRNAs) in 473 colon cancers and 41 adjacent tissues of C…