Xiangyan Wang
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View article: Multi-omics analysis of age-related changes in flavor compounds and lipid molecules of yak meat
Multi-omics analysis of age-related changes in flavor compounds and lipid molecules of yak meat Open
View article: Inhibition of Retinoic Acid Receptor Gamma Improves Bovine Embryo Development
Inhibition of Retinoic Acid Receptor Gamma Improves Bovine Embryo Development Open
Retinoic acid receptor gamma (RARγ) plays a critical but poorly understood role in early embryo development and stem cell pluripotency. Here, we investigated the effects of the RARγ-specific inhibitor LY2955303 (LY) on in vitro-produced bo…
View article: Synergistic Adaptations of Yak Rumen Microbiota, Metabolites and Host to Altitudinal
Synergistic Adaptations of Yak Rumen Microbiota, Metabolites and Host to Altitudinal Open
Rumen microbiota and metabolites play important roles in energy metabolism and immune regulation in the host. However, the underlying mechanisms of their interaction with the host to regulate yak plateau adaptation remain unknown. In this …
View article: Establishing Bovine Embryonic Stem Cells and Dissecting Their Self-Renewal Mechanisms
Establishing Bovine Embryonic Stem Cells and Dissecting Their Self-Renewal Mechanisms Open
Bovine pluripotent stem cells (PSCs) hold significant potential for diverse applications in agriculture, reproductive biotechnology, and biomedical research. However, challenges persist in establishing stable bovine PSC lines and understan…
View article: HDAC11 in ovarian granulosa cells coordinates LH in the maturation of oocytes in Tan sheep
HDAC11 in ovarian granulosa cells coordinates LH in the maturation of oocytes in Tan sheep Open
Oocyte maturation plays an important role in supporting mammalian reproduction. Histone deacetylase 11 (HDAC11), the only member of the class IV histone deacetylase family and the smallest histone deacetylases (HDACs), has been shown to re…
View article: Effects of partial silage replacement with corn stover pellets on the rumen microbiota and serum metabolome of breeding cows
Effects of partial silage replacement with corn stover pellets on the rumen microbiota and serum metabolome of breeding cows Open
Introduction Straw pellet ration replacing part of silage is of great significance for farmers to save farming costs and solve the lack of feed resources. A comprehensive analysis of rumen microbial and serum metabolite compositions is con…
View article: Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks
Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks Open
Introduction The gut microbiota significantly influences the host’s production performance and health status, with different gastrointestinal tissues exhibiting functional diversity reflected in their microbial diversity. Methods In this s…
View article: Effects of Oregano Essential Oil and/or Yeast Cultures on the Rumen Microbiota of Crossbred Simmental Calves
Effects of Oregano Essential Oil and/or Yeast Cultures on the Rumen Microbiota of Crossbred Simmental Calves Open
This study hypothesized that combining oregano essential oil (OEO) and yeast cultures (YCs) would modulate rumen microbiota to promote gastrointestinal homeostasis and function. Twenty-four newborn, healthy, disease-free, crossbred Simment…
View article: Design and Implementation of a Solar Powered Molecular Sieve Chrysanthemum Drying Device
Design and Implementation of a Solar Powered Molecular Sieve Chrysanthemum Drying Device Open
Chrysanthemum is a commonly used traditional Chinese medicine. Facing the high moisture content, easy decay and spoilage, and intolerance to storage of fresh chrysanthemums; Addressing the demand for chrysanthemum processing technology and…
View article: Transcriptomic and Metabolomic Insights into Age-Related Changes in Lung Tissue of Yaks Under Highland Stress
Transcriptomic and Metabolomic Insights into Age-Related Changes in Lung Tissue of Yaks Under Highland Stress Open
As an indigenous species on the Tibetan Plateau, the yak is well adapted to the plateau hypoxic environment. The high-altitude hypoxia adaptation of the yak requires the adaptive reshaping of multiple tissues and organs, especially the lun…
View article: microRNA Temporal-Specific Expression Profiles Reveal longissimus dorsi Muscle Development in Tianzhu White Yak
microRNA Temporal-Specific Expression Profiles Reveal longissimus dorsi Muscle Development in Tianzhu White Yak Open
As a class of regulatory factors, microRNAs (miRNAs) play an important role in regulating normal muscle development and fat deposition. Muscle and adipose tissues, as major components of the animal organism, are also economically important…
View article: Polymorphisms of ACACB Gene and Their Association with Milk Quality Traits in Yak
Polymorphisms of ACACB Gene and Their Association with Milk Quality Traits in Yak Open
Acetyl-CoA carboxylase beta (ACACB) is a rate-limiting enzyme involved in lipid syn-thesis and fatty acid oxidation. The results of our previous study showed that a total of seven SNPs were detected in the exon 37-intron 37, exon 46-intron…
View article: Mutations in the FOXO3 Gene and Their Effects on Meat Traits in Gannan Yaks
Mutations in the FOXO3 Gene and Their Effects on Meat Traits in Gannan Yaks Open
The FOXO3 gene, a prominent member of the FOXO family, has been identified as a potential quantitative trait locus for muscle atrophy and lipid metabolism in livestock. It is also considered a promising candidate gene for meat quality trai…
View article: Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development
Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development Open
Background CircRNAs are a class of noncoding RNAs with tissue- and development-specific expression characteristics. In many mammals, primordial follicle development begins in the embryonic stage. However, the study of circRNAs in primordia…
View article: PEGylated porcine–human recombinant uricase: A novel fusion protein with improved efficacy and safety for the treatment of hyperuricemia and renal complications
PEGylated porcine–human recombinant uricase: A novel fusion protein with improved efficacy and safety for the treatment of hyperuricemia and renal complications Open
The growing prevalence of hyperuricemia necessitates the urgent development of more potent treatments. This study aimed to develop, optimize, and evaluate the safety and efficacy of porcine–human recombinant uricase (PHRU) both in vitro an…
View article: Variation in the HSL Gene and Its Association with Carcass and Meat Quality Traits in Yak
Variation in the HSL Gene and Its Association with Carcass and Meat Quality Traits in Yak Open
Hormone-sensitive lipase (HSL) is involved in the breakdown of triacylglycerols in adipose tissue, which influences muscle tenderness and juiciness by affecting the intramuscular fat content (IMF). This study analyzed the association betwe…
View article: Variation in Acetyl-CoA Carboxylase Beta Gene and Its Effect on Carcass and Meat Traits in Gannan Yaks
Variation in Acetyl-CoA Carboxylase Beta Gene and Its Effect on Carcass and Meat Traits in Gannan Yaks Open
Acetyl-CoA carboxylase beta (ACACB) is a functional candidate gene that impacts fat deposition. In the present study, we sequenced exon 37–intron 37, exon 46–intron 46, and intron 47 of yak ACACB using hybrid pool sequencing to search for …
View article: Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis
Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis Open
Members of the gasdermin (GSDM) family are pore-forming effectors that cause membrane permeabilization and pyroptosis, a lytic proinflammatory type of cell death. To reveal the functional evolution of GSDM-mediated pyroptosis at the transi…
View article: Are Economic Growth Pressures Inhibiting Green Total Factor Productivity Growth?
Are Economic Growth Pressures Inhibiting Green Total Factor Productivity Growth? Open
The purpose of this study is to reveal the impact of economic-growth pressure on green total factor productivity (GTFP) to provide a reference for promoting green development in China. Based on the economic-growth objective-management pers…
View article: Effects of Two Different Straw Pellets on Yak Growth Performance and Ruminal Microbiota during Cold Season
Effects of Two Different Straw Pellets on Yak Growth Performance and Ruminal Microbiota during Cold Season Open
The Tianzhu white yaks (Bos grunniens) live on the Qinghai–Tibet Plateau. During winter, a lack of resources and low nutritional levels seriously affect their growth performance. In this study, we aimed to explore the effect of supplementa…
View article: Long-stranded non-coding RNAs temporal-specific expression profiles reveal longissimus dorsi muscle development and intramuscular fat deposition in Tianzhu white yak
Long-stranded non-coding RNAs temporal-specific expression profiles reveal longissimus dorsi muscle development and intramuscular fat deposition in Tianzhu white yak Open
The process of muscle development and intramuscular fat (IMF) deposition is quite complex and controlled by both mRNAs and ncRNAs. Long-stranded non-coding RNAs (LncRNAs) are involved in various biological processes in mammals while also p…
View article: HDAC1 in the Ovarian Granulosa Cells of Tan Sheep Improves Cumulus Cell Expansion and Oocyte Maturation Independently of the EGF-like Growth Factors
HDAC1 in the Ovarian Granulosa Cells of Tan Sheep Improves Cumulus Cell Expansion and Oocyte Maturation Independently of the EGF-like Growth Factors Open
Previous studies have shown that some of the histone deacetylases (HDACs) play diverse roles in the regulation of ovarian somatic cell development, oocyte maturation and early embryonic development in different species including sheep. Thi…
View article: Acute and Subchronic Oral Toxicity of Anthraquinone in Sprague Dawley Rats
Acute and Subchronic Oral Toxicity of Anthraquinone in Sprague Dawley Rats Open
Objective: This study was conducted to evaluate the acute and subchronic toxicity of anthraquinone. An acute toxicity test was performed in female Sprague Dawley (SD) rats, and the oral median lethal dose (LD50) of anthraquinone was estima…
View article: Inhibition of HMGB1 Ameliorates the Maternal-Fetal Interface Destruction in Unexplained Recurrent Spontaneous Abortion by Suppressing Pyroptosis Activation
Inhibition of HMGB1 Ameliorates the Maternal-Fetal Interface Destruction in Unexplained Recurrent Spontaneous Abortion by Suppressing Pyroptosis Activation Open
Recurrent spontaneous abortion (RSA) is a common complication of pregnancy that affects the physical and mental health of pregnant women, and approximately 50% of the mechanisms are unclear. Our previous studies have found that high mobili…
View article: Rational Constructed Ultra-Small Iron Oxide Nanoprobes Manifesting High Performance for T1-Weighted Magnetic Resonance Imaging of Glioblastoma
Rational Constructed Ultra-Small Iron Oxide Nanoprobes Manifesting High Performance for T1-Weighted Magnetic Resonance Imaging of Glioblastoma Open
Precise diagnosis and monitoring of cancer depend on the development of advanced technologies for in vivo imaging. Owing to the merits of outstanding spatial resolution and excellent soft-tissue contrast, the application of magnetic resona…
View article: Medium- and Long-Term Integrated Demand Response of Integrated Energy System Based on System Dynamics
Medium- and Long-Term Integrated Demand Response of Integrated Energy System Based on System Dynamics Open
For the integrated energy system of coupling electrical, cool and heat energy and gas and other forms of energy, the medium- and long-term integrated demand response of flexible load, energy storage and electric vehicles and other demand s…
View article: Cognitive Switching Affects Arithmetic Strategy Selection: Evidence from Eye-gaze and Behavioral Measures
Cognitive Switching Affects Arithmetic Strategy Selection: Evidence from Eye-gaze and Behavioral Measures Open
Although many studies of cognitive switching have been conducted, little is known about whether and how cognitive switching affects individuals’ use of arithmetic strategies. We used estimation and numerical comparison tasks within the ope…
View article: The Central Executive Mediates the Relationship Between Children’s Approximate Number System Acuity and Arithmetic Strategy Utilization in Computational Estimation
The Central Executive Mediates the Relationship Between Children’s Approximate Number System Acuity and Arithmetic Strategy Utilization in Computational Estimation Open
Studies investigating the relationship between working memory (WM) and approximate number system (ANS) acuity in the area of arithmetic strategy utilization are scarce. The choice/no choice method paradigm was used in the present study to …
View article: Probabilistic Harmonic Analysis on Distributed Photovoltaic Integration Considering Typical Weather Scenarios
Probabilistic Harmonic Analysis on Distributed Photovoltaic Integration Considering Typical Weather Scenarios Open
Distributed Generation (DG) integrating to the network would cause the harmonic pollution which would cause damages on electrical devices and affect the normal operation of power system. On the other hand, due to the randomness of the wind…
View article: Investigation on Performance Prediction and Operation Characteristics of a Parabolic Trough Solar Thermal Collecting System
Investigation on Performance Prediction and Operation Characteristics of a Parabolic Trough Solar Thermal Collecting System Open
Based on the 1MWt parabolic trough concentrating solar power (CSP) pilot plant, the operation characteristics are investigated in three typical weather conditions around the vernal equinox. A simplified performance prediction model is prop…