Xianzhong Zhang
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View article: An Efficient and Robust Dual-Channel Signal Gluing Method for Atmospheric Lidar
An Efficient and Robust Dual-Channel Signal Gluing Method for Atmospheric Lidar Open
Lidar serves as a vital active remote sensing instrument for exploring the atmosphere. However, the detection range of lidar is significantly constrained by the dynamic range of photo-detectors. To mitigate this limitation, atmospheric lid…
View article: RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway
RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway Open
Background Retinoid metabolism is critical for maintaining liver homeostasis, and its dysregulation is closely associated with liver diseases. Retinol binding protein 7 (RBP7) involves in retinoids transport, particularly in liver, indicat…
View article: Unilateral anterior choroidal artery infarction presenting with a temporary stupor
Unilateral anterior choroidal artery infarction presenting with a temporary stupor Open
A 73-year-old woman presented with a temporary stupor and right hemiplegia. Brain magnetic resonance imaging revealed acute infarction of the anterior choroidal artery. The clinical features associated with acute anterior choroidal artery …
View article: Downregulated PTEN and aberrant JAK–STAT signal pathway in essential thrombocythemia patients
Downregulated PTEN and aberrant JAK–STAT signal pathway in essential thrombocythemia patients Open
Background Essential thrombocythemia (ET) is one of the Philadelphia-negative (Ph−) classical myeloproliferative neoplasms (MPNs), characterized by increased megakaryocyte and platelet counts, as well as an increased risk of thrombo-hemorr…
View article: Biotechnological synthesis of nucleoside analogs: Recent progress and perspectives
Biotechnological synthesis of nucleoside analogs: Recent progress and perspectives Open
View article: Chloride channel-3 regulates sodium-iodide symporter expression and localization in the thyroids of mice on a high-iodide diet
Chloride channel-3 regulates sodium-iodide symporter expression and localization in the thyroids of mice on a high-iodide diet Open
Introduction Certain chloride channels and H + /Cl − antiporters, such as chloride channel 3 (ClC-3), are expressed at the apical pole of thyrocytes, facilitating iodide (I − ) efflux. However, the relationship between ClC-3 and I − uptake…
View article: A B7H3-targeting antibody–drug conjugate in advanced solid tumors: a phase 1/1b trial
A B7H3-targeting antibody–drug conjugate in advanced solid tumors: a phase 1/1b trial Open
View article: Author Correction: Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites
Author Correction: Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites Open
View article: Assessment and Spatiotemporal Changes of Multi-Source Temperature and Precipitation Data in Uzbekistan
Assessment and Spatiotemporal Changes of Multi-Source Temperature and Precipitation Data in Uzbekistan Open
View article: Uncertainty Evaluation of Atmospheric Temperature Retrieval Using Rayleigh Lidar Based on the Optimal Estimation Method
Uncertainty Evaluation of Atmospheric Temperature Retrieval Using Rayleigh Lidar Based on the Optimal Estimation Method Open
View article: Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites
Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites Open
View article: Study on the relationship between surface tension and dilational visco‐elasticity with foam stability
Study on the relationship between surface tension and dilational visco‐elasticity with foam stability Open
The replacement of fluorine‐free foam is imminent, but to date, no fluorine‐free foam has reached comparable fire extinguishing performance to AFFF (aqueous film forming foam). The stability of firefighting foam significantly affects its e…
View article: A nitroreductase responsive probe for early diagnosis of pulmonary fibrosis disease
A nitroreductase responsive probe for early diagnosis of pulmonary fibrosis disease Open
Idiopathic pulmonary fibrosis (IPF) is a serious interstitial lung disease. However, the definitive diagnosis of IPF is impeded by the limited capabilities of current diagnostic methods, which may fail to capture the optimal timing for tre…
View article: MicroPET Imaging of Riboflavin Transporter 3 Expression in Myocardial Infarction/Reperfusion Rat Models with Radiofluorinated Riboflavin
MicroPET Imaging of Riboflavin Transporter 3 Expression in Myocardial Infarction/Reperfusion Rat Models with Radiofluorinated Riboflavin Open
Riboflavin transporter 3 (RFVT3) represents a potential cardioprotective biotarget in energetic metabolism reprogramming after myocardial infarction/reperfusion (MI/R). This study investigated the feasibility of noninvasive real-time quant…
View article: Application of 99mTc-Labeled WL12 Peptides as a Tumor PD-L1-Targeted SPECT Imaging Agent: Kit Formulation, Preclinical Evaluation, and Study on the Influence of Coligands
Application of 99mTc-Labeled WL12 Peptides as a Tumor PD-L1-Targeted SPECT Imaging Agent: Kit Formulation, Preclinical Evaluation, and Study on the Influence of Coligands Open
With the development of PD-1/PD-L1 immune checkpoint inhibitor therapy, the ability to monitor PD-L1 expression in the tumor microenvironment is important for guiding therapy. This study was performed to develop a novel radiotracer with op…
View article: Preclinical Evaluation of <sup>131</sup>I/<sup>18</sup>F-Labeled Covalent Small-Molecule Inhibitors for STING Status Imaging
Preclinical Evaluation of <sup>131</sup>I/<sup>18</sup>F-Labeled Covalent Small-Molecule Inhibitors for STING Status Imaging Open
The stimulator of interferon genes (STING) is a vital protein to the immune surveillance of the tumor microenvironment. In this study, we develop novel inhibitor-based radioligands and evaluate their feasibility for noninvasive visualizati…
View article: A proof-of-concept study on bioorthogonal-based pretargeting and signal amplify radiotheranostic strategy
A proof-of-concept study on bioorthogonal-based pretargeting and signal amplify radiotheranostic strategy Open
View article: Preclinical evaluation of the theranostic potential of 89Zr/177Lu-labeled anti-TROP-2 antibody in triple-negative breast cancer model
Preclinical evaluation of the theranostic potential of 89Zr/177Lu-labeled anti-TROP-2 antibody in triple-negative breast cancer model Open
Background Triple-negative breast cancer (TNBC) is one of the most lethal malignant tumors among women, characterized by high invasiveness, high heterogeneity, and lack of specific therapeutic targets such as estrogen receptor, progesteron…
View article: Bioinformatics screening and verification of ischemic stroke-related key genes and drug prediction
Bioinformatics screening and verification of ischemic stroke-related key genes and drug prediction Open
Stroke is one of the major causes of disability and death worldwide. The lack of effective medical treatment for stroke heightens the need for new therapeutic targets. In this study, we obtained two microarray data sets from the Gene Expre…
View article: Expression of concern: Gadolinium embedded iron oxide nanoclusters as <i>T</i><sub>1</sub>–<i>T</i><sub>2</sub> dual-modal MRI-visible vectors for safe and efficient siRNA delivery
Expression of concern: Gadolinium embedded iron oxide nanoclusters as <i>T</i><sub>1</sub>–<i>T</i><sub>2</sub> dual-modal MRI-visible vectors for safe and efficient siRNA delivery Open
Expression of concern for ‘Gadolinium embedded iron oxide nanoclusters as T 1 – T 2 dual-modal MRI-visible vectors for safe and efficient siRNA delivery’ by Xiaoyong Wang et al. , Nanoscale , 2013, 5 , 8098–8104, https://doi.org/10.1039/C3…
View article: Efficacy of traditional Chinese medicine external therapy on sleep quality in patients with cancer: A systematic review and network meta-analysis
Efficacy of traditional Chinese medicine external therapy on sleep quality in patients with cancer: A systematic review and network meta-analysis Open
CRD42022381370.
View article: HOXC13 promotes cell proliferation, metastasis and glycolysis in breast cancer by regulating DNMT3A
HOXC13 promotes cell proliferation, metastasis and glycolysis in breast cancer by regulating DNMT3A Open
Breast cancer (BC) is a life-threatening malignant tumor that affects females more commonly than males. The mechanisms underlying BC proliferation, metastasis and glycolysis require further investigation. Homeobox C13 (HOXC13) is highly ex…
View article: Data from Targeted Radionuclide Therapy in Patient-Derived Xenografts Using <sup>177</sup>Lu-EB-RGD
Data from Targeted Radionuclide Therapy in Patient-Derived Xenografts Using <sup>177</sup>Lu-EB-RGD Open
Currently, most patients with non–small cell lung cancer (NSCLC) are diagnosed in advanced stages with a poor five-year survival rate. Therefore, intensive research aimed at finding novel therapeutic strategies has been ongoing; experiment…
View article: Supplementary Data from Targeted Radionuclide Therapy in Patient-Derived Xenografts Using <sup>177</sup>Lu-EB-RGD
Supplementary Data from Targeted Radionuclide Therapy in Patient-Derived Xenografts Using <sup>177</sup>Lu-EB-RGD Open
Supplementary Data
View article: Supplementary Data from Targeted Radionuclide Therapy in Patient-Derived Xenografts Using <sup>177</sup>Lu-EB-RGD
Supplementary Data from Targeted Radionuclide Therapy in Patient-Derived Xenografts Using <sup>177</sup>Lu-EB-RGD Open
Supplementary Data
View article: Data from Targeted Radionuclide Therapy in Patient-Derived Xenografts Using <sup>177</sup>Lu-EB-RGD
Data from Targeted Radionuclide Therapy in Patient-Derived Xenografts Using <sup>177</sup>Lu-EB-RGD Open
Currently, most patients with non–small cell lung cancer (NSCLC) are diagnosed in advanced stages with a poor five-year survival rate. Therefore, intensive research aimed at finding novel therapeutic strategies has been ongoing; experiment…
View article: Supplementary Data from A Paradigm of Cancer Immunotherapy Based on 2-[<sup>18</sup>F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect
Supplementary Data from A Paradigm of Cancer Immunotherapy Based on 2-[<sup>18</sup>F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect Open
Supplementary Data from A Paradigm of Cancer Immunotherapy Based on 2-[18F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect
View article: Data from A Paradigm of Cancer Immunotherapy Based on 2-[<sup>18</sup>F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect
Data from A Paradigm of Cancer Immunotherapy Based on 2-[<sup>18</sup>F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect Open
Purpose:Efforts have been devoted to select eligible candidates for PD-1/PD-L1 immune checkpoint blocker (ICB) immunotherapy. Here, we have a serendipitous finding of positron emission tomography (PET) imaging tracer 2-[18F]FDG …
View article: Data from A Paradigm of Cancer Immunotherapy Based on 2-[<sup>18</sup>F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect
Data from A Paradigm of Cancer Immunotherapy Based on 2-[<sup>18</sup>F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect Open
Purpose:Efforts have been devoted to select eligible candidates for PD-1/PD-L1 immune checkpoint blocker (ICB) immunotherapy. Here, we have a serendipitous finding of positron emission tomography (PET) imaging tracer 2-[18F]FDG …
View article: Supplementary Data from A Paradigm of Cancer Immunotherapy Based on 2-[<sup>18</sup>F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect
Supplementary Data from A Paradigm of Cancer Immunotherapy Based on 2-[<sup>18</sup>F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect Open
Supplementary Data from A Paradigm of Cancer Immunotherapy Based on 2-[18F]FDG and Anti–PD-L1 mAb Combination to Enhance the Antitumor Effect