Xianjun Wang
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View article: A Multi-center Clinical Evaluation of Polymerase chain reaction coupled with quantum dot fluorescence analysis and Quantitative Real-Time Reverse Transcription Polymerase Chain Reaction for diagnosing pathogens in suspected respiratory infection patients
A Multi-center Clinical Evaluation of Polymerase chain reaction coupled with quantum dot fluorescence analysis and Quantitative Real-Time Reverse Transcription Polymerase Chain Reaction for diagnosing pathogens in suspected respiratory infection patients Open
View article: [Retracted] AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway
[Retracted] AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway Open
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the immunohistochemical data shown in Fig. 1C on p. 5 were strikingly similar to data appearing in different form in anot…
View article: Exploring the spatiotemporal effects of meteorological factors on hand, foot and mouth disease: a multiscale geographically and temporally weighted regression study
Exploring the spatiotemporal effects of meteorological factors on hand, foot and mouth disease: a multiscale geographically and temporally weighted regression study Open
The influence of meteorological factors on hand, foot, and mouth disease (HFMD) is not on the same scale, it's rare for previous studies to measure and recognize the independent regression relationship between each variable in space and ti…
View article: Emergence of Eurasian Avian-Like Swine Influenza A (H1N1) virus in a child in Shandong Province, China
Emergence of Eurasian Avian-Like Swine Influenza A (H1N1) virus in a child in Shandong Province, China Open
View article: Application of Multi-threading Mechanisms to the Connect6 Gaming System
Application of Multi-threading Mechanisms to the Connect6 Gaming System Open
The field of computer games is currently a popular research direction in the field of artificial intelligence, and has a pivotal position in the development and research of artificial intelligence. In the field of computer games, Connect6 …
View article: Study of Road-based Versus Pattern-based Game Strategies in Connect6
Study of Road-based Versus Pattern-based Game Strategies in Connect6 Open
Computer game is an important branch in the field of artificial intelligence research nowadays, and the in-depth study of computer game can not only promote the development of game theory, but also contribute to the development of artifici…
View article: Topology reconstruction for asymmetric systems by isomorphic mapping or perturbation approximation
Topology reconstruction for asymmetric systems by isomorphic mapping or perturbation approximation Open
The systems without symmetries, e.g. the spatial and chiral symmetries, are generally thought to be improper for topological study and no conventional integral topological invariant can be well defined. In this work, with multi-band asymme…
View article: Modification effects of long-term air pollution levels on the relationship between short-term exposure to meteorological factors and hand, foot, and mouth disease: A distributed lag non-linear model-based study in Shandong Province, China
Modification effects of long-term air pollution levels on the relationship between short-term exposure to meteorological factors and hand, foot, and mouth disease: A distributed lag non-linear model-based study in Shandong Province, China Open
The occurrence of hand, foot, and mouth disease (HFMD) is closely related to meteorological factors. However, location-specific characteristics, such as persistent air pollution, may increase the complexity of the impact of meteorological …
View article: Proteomic analysis revealed the function of PoElp3 in development, pathogenicity, and autophagy through the tRNA-mediated translation efficiency in the rice blast fungus
Proteomic analysis revealed the function of PoElp3 in development, pathogenicity, and autophagy through the tRNA-mediated translation efficiency in the rice blast fungus Open
The Elongator complex is conserved in a wide range of species and plays crucial roles in diverse cellular processes. We have previously shown that the Elongator protein PoELp3 was involved in the asexual development, pathogenicity, and aut…
View article: Development and internal-external validation of the ATHE Scale: predicting acute large vessel occlusion due to underlying intracranial atherosclerosis prior to endovascular treatment
Development and internal-external validation of the ATHE Scale: predicting acute large vessel occlusion due to underlying intracranial atherosclerosis prior to endovascular treatment Open
OBJECTIVE The diagnosis of intracranial atherosclerosis (ICAS) associated with large vessel occlusion (LVO) before endovascular treatment (EVT) remains a clinical challenge. This study was aimed at developing a predictive model for ICAS-LV…
View article: White matter hyperintensity burden and collateral circulation in acute ischemic stroke with large artery occlusion
White matter hyperintensity burden and collateral circulation in acute ischemic stroke with large artery occlusion Open
View article: Changes in Cytokine Levels in Patients with Severe Fever with Thrombocytopenia Syndrome Virus
Changes in Cytokine Levels in Patients with Severe Fever with Thrombocytopenia Syndrome Virus Open
The research exhibited that the SFTS virus (SFTSV) caused an atypical manifestation of cytokines. The levels of IL-6, IP-10, MIP-1α, and MCP-1 had been observed a positive association with the severity of the illness.
View article: Origin and evolution of the triploid cultivated banana genome
Origin and evolution of the triploid cultivated banana genome Open
View article: Sugar distributions on gangliosides guide the formation and stability of amyloid-β oligomers
Sugar distributions on gangliosides guide the formation and stability of amyloid-β oligomers Open
View article: Free-hand bedside catheter evacuation without 3D reconstruction for extensive revascularization-associated hemorrhage after ischemic stroke
Free-hand bedside catheter evacuation without 3D reconstruction for extensive revascularization-associated hemorrhage after ischemic stroke Open
Objective: To evaluate the feasibility of free-hand bedside catheterization using axial computed tomography (CT) in patients with brain hemorrhage after ischemic revascularization. Methods: Patients who received revascularization therapy a…
View article: Caffeine ameliorates the metabolic syndrome in diet-induced obese mice through regulating the gut microbiota and serum metabolism
Caffeine ameliorates the metabolic syndrome in diet-induced obese mice through regulating the gut microbiota and serum metabolism Open
View article: Genomic Epidemiology and Transmission Dynamics of Global Coxsackievirus B4
Genomic Epidemiology and Transmission Dynamics of Global Coxsackievirus B4 Open
The aim of this study was to determine the global genetic diversity and transmission dynamics of coxsackievirus B4 (CVB4) and to propose future directions for disease surveillance. Next-generation sequencing was performed to obtain the com…
View article: Effects of ambient temperature on influenza-like illness: A multicity analysis in Shandong Province, China, 2014–2017
Effects of ambient temperature on influenza-like illness: A multicity analysis in Shandong Province, China, 2014–2017 Open
Background The associations between ambient temperature and influenza-like illness (ILI) have been investigated in previous studies. However, they have inconsistent results. The purpose of this study was to estimate the effect of ambient t…
View article: Genetic characterization and molecular epidemiology of Coxsackievirus A12 from mainland China during 2010–2019
Genetic characterization and molecular epidemiology of Coxsackievirus A12 from mainland China during 2010–2019 Open
Coxsackievirus A12 (CVA12) is an enterovirus that has been isolated in many countries in recent years. However, studies on CVA12 are limited, and its effective population size, evolutionary dynamics and recombination patterns have not been…
View article: Surveillance of avian influenza viruses in live bird markets of Shandong province from 2013 to 2019
Surveillance of avian influenza viruses in live bird markets of Shandong province from 2013 to 2019 Open
Avian influenza viruses (AIVs) seriously affect the poultry industry and pose a great threat to humans. Timely surveillance of AIVs is the basis for preparedness of the virus. This study reported the long-term surveillance of AIVs in the l…
View article: Identification of Monobenzone as a Novel Potential Anti-Acute Myeloid Leukaemia Agent That Inhibits RNR and Suppresses Tumour Growth in Mouse Xenograft Model
Identification of Monobenzone as a Novel Potential Anti-Acute Myeloid Leukaemia Agent That Inhibits RNR and Suppresses Tumour Growth in Mouse Xenograft Model Open
Acute myeloid leukaemia (AML) is one of the most common types of haematopoietic malignancy. Ribonucleotide reductase (RNR) is a key enzyme required for DNA synthesis and cell proliferation, and its small subunit RRM2 plays a key role for t…
View article: Epidemiological Characteristics of Human Rabies - Shandong Province, China, 2010-2020.
Epidemiological Characteristics of Human Rabies - Shandong Province, China, 2010-2020. Open
Dogs were still the primary animal hosts. Most rabies patients died due to no or inadequate post-exposure prophylaxis. Vaccine inoculation rates for dogs should reach the target of 70% as soon as possible. Health departments should improve…
View article: Caffeine Ameliorates the Metabolic Syndrome in Diet-induced Obese Mice Through Regulating the Gut Microbiota and Serum Metabolism
Caffeine Ameliorates the Metabolic Syndrome in Diet-induced Obese Mice Through Regulating the Gut Microbiota and Serum Metabolism Open
Objective Obesity is associated with gut microbiota disorders, which has been related to developing metabolic syndromes. The research aims to investigate the effects of caffeine treatment on insulin resistance, intestinal microbiota compos…
View article: Association of Stroke Subtype With Hemorrhagic Transformation Mediated by Thrombectomy Pass: Data From the ANGEL-ACT Registry
Association of Stroke Subtype With Hemorrhagic Transformation Mediated by Thrombectomy Pass: Data From the ANGEL-ACT Registry Open
Background: The role of stroke etiology subtype in patients with acute large vessel occlusion on the occurrence of hemorrhagic transformation (HT) after endovascular treatment is poorly studied, and which factors mediate their relationship…
View article: 泊松比对川藏铁路嘉黎断裂附近地应力场的影响
泊松比对川藏铁路嘉黎断裂附近地应力场的影响 Open
摘要: 川藏铁路在波密跨越嘉黎断裂,研究其周边地应力场对认识嘉黎断裂对川藏铁路廊道地应力场的影响至关重要.通过数值模型计算了通古地区及其邻近鲁朗、多康地区地应力场,通过对比3个模型的加载条件和力学参数差异,分析了沿嘉黎断裂带地应力场与周边区域地应力场的不同.结果表明:(1)总体来看,随深度变化的泊松比,能更好地拟合实测地应力数据;(2)地应力场区域差异明显,多康地区地应力较高,挤压明显,而鲁朗地区挤压程度仅为多康地区1/3左右,通古地区跨越嘉黎断裂带,应力场显示挤压很弱,可…
View article: Genome and annotation of triploid cultivated banana
Genome and annotation of triploid cultivated banana Open
Genome assemblies and annotations of Cavendish and Gros Michel bananas
View article: Efficacy and safety of direct balloon angioplasty in the treatment of large atherosclerotic stroke
Efficacy and safety of direct balloon angioplasty in the treatment of large atherosclerotic stroke Open
Direct balloon angioplasty may be a safe and effective method for the treatment of stroke caused by intracranial large arteriosclerosis occlusion.
View article: AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway
AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway Open
Acute lung injury (ALI) is a respiratory tract disease characterized by increased alveolar/capillary permeability, lung inflammation and structural damage to lung tissues, which can progress and transform into acute respiratory distress sy…
View article: Endovascular treatment for acute ischemic stroke in patients with versus without atrial fibrillation: a matched-control study
Endovascular treatment for acute ischemic stroke in patients with versus without atrial fibrillation: a matched-control study Open
View article: Thrombectomy Versus Combined Thrombolysis and Thrombectomy in Patients With Acute Stroke
Thrombectomy Versus Combined Thrombolysis and Thrombectomy in Patients With Acute Stroke Open
Background and Purpose: A recent randomized controlled trial DIRECT-MT (Direct Intra-Arterial Thrombectomy to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals) compared the safety and efficac…