Xinhua Yu
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View article: Fluoride Exposure Among U.S. Children Aged ≤ 19 Years: Findings from NHANES 2013–2016
Fluoride Exposure Among U.S. Children Aged ≤ 19 Years: Findings from NHANES 2013–2016 Open
Community water fluoridation is a key public health intervention, yet ongoing debates about systemic risks call for evidence on fluoride exposure. We analyzed NHANES 2013–2016 biomonitoring data to assess fluoride exposure in children and …
View article: Comparison of periglottic oxygen fraction, tracheal oxygen fraction and safe apnea time under different apneic oxygenation techniques: a randomised non-inferiority controlled study
Comparison of periglottic oxygen fraction, tracheal oxygen fraction and safe apnea time under different apneic oxygenation techniques: a randomised non-inferiority controlled study Open
The study was approved by the Ethics Committee of the Obstetrics and Gynaecology Hospital of Fudan University (2022-197) on January 9, 2023. The study was registered on ChiCTR (ChiCTR2300067642) on January 16, 2023.
View article: Clinical characteristics and outcome in patients with anti-AMPAR2 encephalitis: a case series and literature review
Clinical characteristics and outcome in patients with anti-AMPAR2 encephalitis: a case series and literature review Open
Anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis is a rare autoimmune encephalitis, with only a few series describing its typical clinical manifestations and prognosis. Here, we present three newly identi…
View article: Public health diplomacy: summary of the methods and outcome of the 1st University of Memphis School of Public Health Diplomacy Summit
Public health diplomacy: summary of the methods and outcome of the 1st University of Memphis School of Public Health Diplomacy Summit Open
Public health diplomacy addresses global challenges impacting societies, economies, the environment, and health by integrating foreign policy and development. The University of Memphis School of Public Health hosted a multistakeholder summ…
View article: Neutrophils negatively control IL-17A-producing γδ T cell frequencies in a contact-dependent manner under physiological conditions
Neutrophils negatively control IL-17A-producing γδ T cell frequencies in a contact-dependent manner under physiological conditions Open
Background In addition to serving as the primary effector cells against infections, neutrophils have been implicated in the regulation of both innate and adaptive immunity. In this study, we aimed to investigate the role of neutrophils in …
View article: Positive association between chronic hepatitis B virus infection and anemia in pregnancy in Southern China
Positive association between chronic hepatitis B virus infection and anemia in pregnancy in Southern China Open
This observational investigation aimed to explore potential risk factors for anemia in pregnancy. Firstly, a cross-sectional study was conducted, encompassing a review of clinical data of 43,201 pregnant women admitted to the Hainan Women …
View article: Bidirectional Associations Between Alcohol Drinking and Depressive Symptoms Among US Adults Aged 50 to 75: The US Health and Retirement Study
Bidirectional Associations Between Alcohol Drinking and Depressive Symptoms Among US Adults Aged 50 to 75: The US Health and Retirement Study Open
Background/Objectives: Low or moderate alcohol drinking may reduce the risk of depression, but depression may induce alcohol drinking. However, the bidirectional associations between alcohol drinking and depression were inconsistent, and m…
View article: Discontinuation of Antidepressants and the Risk of Medication Resumption among Community-Dwelling Older Adults with Depression in the US
Discontinuation of Antidepressants and the Risk of Medication Resumption among Community-Dwelling Older Adults with Depression in the US Open
Antidepressants are among the most prescribed drugs in the US, but the current treatment patterns and modalities among older adults are unclear. This study assessed the patterns of discontinuation of antidepressants and the risk of medicat…
View article: Burden of Chronic and Heavy Opioid Use Among Elderly Community Dwellers in the U.S.
Burden of Chronic and Heavy Opioid Use Among Elderly Community Dwellers in the U.S. Open
Among elderly Medicare beneficiaries, opioid prescriptions have been decreasing since 2013. However, a substantial number of elderly people were chronic and heavy users, calling for better opioid management among them.
View article: Air exposure and cell differentiation are essential for investigation of SARS-CoV-2 entry genes in human primary airway epithelial cells in vitro
Air exposure and cell differentiation are essential for investigation of SARS-CoV-2 entry genes in human primary airway epithelial cells in vitro Open
Background In-vitro models of differentiated primary human airway epithelial cells are a valuable tool to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Through the use of these models, it has been shown that…
View article: The effectiveness of different education methods conducted at different times for decreasing the time required for a parturient to position herself for epidural placement
The effectiveness of different education methods conducted at different times for decreasing the time required for a parturient to position herself for epidural placement Open
Background Decreasing the anaesthesia preparation time for primiparas experiencing painful uterine contractions is clinically relevant. This prospective intervention study investigated the effect of various educational methods conducted at…
View article: Role of modified nasopharyngeal oxygen therapy in apnoeic oxygenation under general anaesthesia: A single-centre, randomized controlled clinical study
Role of modified nasopharyngeal oxygen therapy in apnoeic oxygenation under general anaesthesia: A single-centre, randomized controlled clinical study Open
Apnoeic oxygenation is particularly important for patients who cannot be intubated/oxygenate after anaesthesia induction. We aimed to compare safe apnoea times between patients receiving modified nasopharyngeal oxygen therapy and those rec…
View article: Racial Disparities in the Heavy Metal Contamination of Urban Soil in the Southeastern United States
Racial Disparities in the Heavy Metal Contamination of Urban Soil in the Southeastern United States Open
(1) Background: Field monitoring data for addressing the disproportional burden of exposure to soil contamination in communities of minority and low socioeconomic status (SES) are sparse. This study aims to examine the association between …
View article: Effects of delta-opioid receptor agonist pretreatment on the cardiotoxicity of bupivacaine in rats
Effects of delta-opioid receptor agonist pretreatment on the cardiotoxicity of bupivacaine in rats Open
Background Delta-opioid receptor is widely expressed in human and rodent hearts, and has been proved to protect cardiomyocytes against ischemia/reperfusion and heart failure. The antagonist of delta-opioid receptor could block the rescue e…
View article: High Levels of Circulating IL-8 and Soluble IL-2R Are Associated With Prolonged Illness in Patients With Severe COVID-19
High Levels of Circulating IL-8 and Soluble IL-2R Are Associated With Prolonged Illness in Patients With Severe COVID-19 Open
Objectives The coordinated immune response of the host is the key of the successful combat of the body against SARS-CoV-2 infection and is decisive for the development and progression of COVID-19. In this study, we aimed to investigate whe…
View article: Association of Cigarette Smoking, COPD, and Lung Cancer With Expression of SARS-CoV-2 Entry Genes in Human Airway Epithelial Cells
Association of Cigarette Smoking, COPD, and Lung Cancer With Expression of SARS-CoV-2 Entry Genes in Human Airway Epithelial Cells Open
SARS-CoV-2 enters into human airway epithelial cells via membrane fusion or endocytosis, and this process is dependent on ACE2, TMPRSS2, and cathepsin L. In this study, we examined the expression profiles of the three SARS-CoV-2 entry gene…
View article: Expression of ACE2, TMPRSS2 and CTSL in human airway epithelial cells under physiological and pathological conditions: Implications for SARS-CoV-2 infection
Expression of ACE2, TMPRSS2 and CTSL in human airway epithelial cells under physiological and pathological conditions: Implications for SARS-CoV-2 infection Open
SARS-CoV-2 enters into human airway epithelial cells via membrane fusion or endocytosis, and this process is dependent on ACE2, TMPRSS2, and cathepsin L. In this study, we examined the expression profiles of the three SARS-CoV-2 entry-rela…
View article: Risk Interactions of Coronavirus Infection across Age Groups after the Peak of COVID-19 Epidemic
Risk Interactions of Coronavirus Infection across Age Groups after the Peak of COVID-19 Epidemic Open
Background: The COVID-19 pandemic has incurred significant disease burden worldwide, particularly on the elderly population. This study aims to explore how risks of coronavirus infection interact across age groups using data from South Kor…
View article: Distinctive trajectories of COVID-19 epidemic by age and gender: a retrospective modeling of the epidemic in South Korea
Distinctive trajectories of COVID-19 epidemic by age and gender: a retrospective modeling of the epidemic in South Korea Open
Objectives Elderly people had suffered disproportional burden of COVID-19. We hypothesized that males and females in different age groups might have different epidemic trajectories. Methods Using publicly available data from South Korea, d…
View article: Risk interactions of coronavirus infection across age groups after the peak of COVID-19 epidemic
Risk interactions of coronavirus infection across age groups after the peak of COVID-19 epidemic Open
Background the COVID-19 pandemic has incurred significant disease burden worldwide, particularly on elderly population. This study aims to explore how risks of infection interact across age groups using data from South Korea. Methods Daily…
View article: Health service inequalities during the COVID-19 pandemic among elderly people living in large urban and non-urban areas in Florida, US
Health service inequalities during the COVID-19 pandemic among elderly people living in large urban and non-urban areas in Florida, US Open
Objectives Health inequalities were often exacerbated during the emerging epidemic. This study examined urban and non-urban inequalities in health services among COVID-19 patients aged 65 or above in US Florida from March 2 to May 27, 2020…