Xianzhen He
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View article: Recent Clinical Updates of Hypertrophic Cardiomyopathy and Future Therapeutic Strategies
Recent Clinical Updates of Hypertrophic Cardiomyopathy and Future Therapeutic Strategies Open
Hypertrophic cardiomyopathy (HCM) is the most prevalent inherited cardiomyopathy transmitted in an autosomal dominant manner to offspring. It is characterized by unexplained asymmetrical hypertrophy primarily affecting the left ventricle a…
View article: The role of islet autoantigen-specific T cells in the onset and treatment of type 1 diabetes mellitus
The role of islet autoantigen-specific T cells in the onset and treatment of type 1 diabetes mellitus Open
Type 1 diabetes mellitus (T1DM), a complex chronic disease with an intricate etiology and pathogenesis, involves the recognition of self-antigens by pancreatic islet autoantigen-specific T cells and plays crucial roles in both early- and l…
View article: Glucagon-like peptide-1 receptor agonists in neoplastic diseases
Glucagon-like peptide-1 receptor agonists in neoplastic diseases Open
Glucagon-like peptide-1 receptor agonist (GLP-1RA), a novel hypoglycemic agent for the treatment of type 2 diabetes, has well-known effects such as lowering blood sugar, ameliorating inflammation, reducing weight, and lowering blood lipids…
View article: Exploring the associations between gut microbiota composition and SARS-CoV-2 inactivated vaccine response in mice with type 2 diabetes mellitus
Exploring the associations between gut microbiota composition and SARS-CoV-2 inactivated vaccine response in mice with type 2 diabetes mellitus Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination is crucial for protecting vulnerable individuals, yet individuals with type 2 diabetes mellitus (T2DM) often exhibit impaired vaccine responses. Emerging evidence sug…