Xianzhi Liu
YOU?
Author Swipe
View article: A novel, facile, low-cost, energy-free magnetic field device for regulating energy levels and its application in the cold storage and shelf of edible-window-period kiwifruit
A novel, facile, low-cost, energy-free magnetic field device for regulating energy levels and its application in the cold storage and shelf of edible-window-period kiwifruit Open
View article: P4HB regulates tumor-associated macrophage polarization and chemotaxis by enhancing IL-6 cytokine secretion in glioblastoma
P4HB regulates tumor-associated macrophage polarization and chemotaxis by enhancing IL-6 cytokine secretion in glioblastoma Open
Background: Prolyl 4-hydroxylase subunit beta (P4HB) has been linked to glioma progression and treatment resistance; however, its role in the tumor microenvironment regulation remains unclear. Materials and Methods: A total of 90 human gli…
View article: DLGAP5 Promotes Acute Liver Injury via Hepatocyte Pyroptosis-Driven Macrophage Metabolic Reprogramming and M1 Polarization
DLGAP5 Promotes Acute Liver Injury via Hepatocyte Pyroptosis-Driven Macrophage Metabolic Reprogramming and M1 Polarization Open
Pyroptosis is a novel programmed cell death that exists in inflammatory diseases and methyltransferase-like 3 (METTL3) is a core N6-methyladenosine (m6A) modified methyltransferase that has been shown to regulate cell fate. However, the ro…
View article: BANSMDA: a computational model for predicting potential microbe-disease associations based on bilinear attention networks and sparse autoencoders
BANSMDA: a computational model for predicting potential microbe-disease associations based on bilinear attention networks and sparse autoencoders Open
Introduction Predicting the relationship between diseases and microbes can significantly enhance disease diagnosis and treatment, while providing crucial scientific support for public health, ecological health, and drug development. Method…
View article: Elevation of C-reactive protein and homocysteine levels as reliable biomarkers for assessing injury severity and prognosis in traumatic brain injury
Elevation of C-reactive protein and homocysteine levels as reliable biomarkers for assessing injury severity and prognosis in traumatic brain injury Open
This study evaluated the clinical utility of C-reactive protein (CRP) and homocysteine (Hcy) as biomarkers for injury severity assessment and prognostic prediction in traumatic brain injury (TBI). A retrospective cohort study included 103 …
View article: Biomarker identification associated with M2 tumor-associated macrophage infiltration in glioblastoma
Biomarker identification associated with M2 tumor-associated macrophage infiltration in glioblastoma Open
Purpose M2 phenotype tumor-associated macrophages (TAMs) can promote tumor growth, invasion, chemotherapy resistance and so on, leading to malignant progression. The aim of this study was to identify novel prognostic profiles in glioblasto…
View article: Inhibiting ADORA1 enhances glioma apoptosis and increases its sensitivity to anti-PD1 therapy
Inhibiting ADORA1 enhances glioma apoptosis and increases its sensitivity to anti-PD1 therapy Open
Introduction Glioma, the primary cancerous tumor of the central nervous system in adults, has a poor outlook. Immune checkpoint blockade therapy has exhibited notable efficacy against various cancer types. Prior research has suggested that…
View article: BANNMDA: a computational model for predicting potential microbe–drug associations based on bilinear attention networks and nuclear norm minimization
BANNMDA: a computational model for predicting potential microbe–drug associations based on bilinear attention networks and nuclear norm minimization Open
Introduction Predicting potential associations between microbes and drugs is crucial for advancing pharmaceutical research and development. In this manuscript, we introduced an innovative computational model named BANNMDA by integrating Bi…
View article: Mechanistic Insights into Polyol Enhancement on Mechanical and Hydration Characteristics of Rice Starch Gels
Mechanistic Insights into Polyol Enhancement on Mechanical and Hydration Characteristics of Rice Starch Gels Open
View article: Benefit of Surgery for T4bM0 Colon Cancer Patients: Propensity Score Matching and Prognosis Analysis
Benefit of Surgery for T4bM0 Colon Cancer Patients: Propensity Score Matching and Prognosis Analysis Open
View article: <scp>ADAR1</scp> Promotes the Progression and Temozolomide Resistance of Glioma Through p62‐Mediated Selective Autophagy
<span>ADAR1</span> Promotes the Progression and Temozolomide Resistance of Glioma Through p62‐Mediated Selective Autophagy Open
Background Resistance to temozolomide (TMZ) remains is an important cause of treatment failure in patients with glioblastoma multiforme (GBM). ADAR1, as a member of the ADAR family, plays an important role in cancer progression and chemoth…
View article: Periplakin Attenuates Liver Fibrosis via Reprogramming CD44Low Cells into CD44High Liver Progenitor Cells
Periplakin Attenuates Liver Fibrosis via Reprogramming CD44Low Cells into CD44High Liver Progenitor Cells Open
View article: IDH-mutant glioma risk stratification via whole slide images: Identifying pathological feature associations
IDH-mutant glioma risk stratification via whole slide images: Identifying pathological feature associations Open
This article aims to develop and validate a pathological prognostic model for predicting prognosis in patients with isocitrate dehydrogenase (IDH)-mutant gliomas and reveal the biological underpinning of the prognostic pathological feature…
View article: A Microbe-Drug Association Prediction Model Based on Graph Attention Network and Rotating Forest
A Microbe-Drug Association Prediction Model Based on Graph Attention Network and Rotating Forest Open
Background In recent years, drug abuse has led to the increase of microbial resistance, therefore exploring possible connections between drugs and microorganisms becomes more and more important. However, since traditional biological experi…
View article: Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the <scp>ANXA2</scp>/<scp>STAT3</scp> axis
Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the <span>ANXA2</span>/<span>STAT3</span> axis Open
Aims Although radiotherapy is a core treatment modality for various human cancers, including glioblastoma multiforme (GBM), its clinical effects are often limited by radioresistance. The specific molecular mechanisms underlying radioresist…
View article: ZRRD-MBNet：Zero-Reference RETINEX Decomposition-Based Multi-Branch Network for Low-Light Image Enhancement
ZRRD-MBNet：Zero-Reference RETINEX Decomposition-Based Multi-Branch Network for Low-Light Image Enhancement Open
To address the challenges of low visibility, poor contrast, and significant noise in images captured under various extreme conditions, such as backlighting and low-light situations, we propose a novel zero-reference Retinex decomposition-b…
View article: Activated hepatic stellate cell-derived Bmp-1 induces liver fibrosis via mediating hepatocyte epithelial-mesenchymal transition
Activated hepatic stellate cell-derived Bmp-1 induces liver fibrosis via mediating hepatocyte epithelial-mesenchymal transition Open
View article: NMGMDA: a computational model for predicting potential microbe–drug associations based on minimize matrix nuclear norm and graph attention network
NMGMDA: a computational model for predicting potential microbe–drug associations based on minimize matrix nuclear norm and graph attention network Open
The prediction of potential microbe–drug associations is of great value for drug research and development, especially, methods, based on deep learning, have been achieved significant improvement in bio-medicine. In this manuscript, we prop…
View article: Mitochondrial Dysfunction by FADDosome Promotes Gastric Mucosal Injury in Portal Hypertensive Gastropathy
Mitochondrial Dysfunction by FADDosome Promotes Gastric Mucosal Injury in Portal Hypertensive Gastropathy Open
Mucosal epithelial death is an essential pathological characteristic of portal hypertensive gastropathy (PHG). FADDosome can regulate mucosal homeostasis by controlling mitochondrial status and cell death. However, it remains ill-defined w…
View article: NMGMDA: A Computational Model for Predicting Potential Microbe–Drug Associations based on Minimize Matrix Nuclear Norm and Graph Attention Network
NMGMDA: A Computational Model for Predicting Potential Microbe–Drug Associations based on Minimize Matrix Nuclear Norm and Graph Attention Network Open
For drug research and development, the probable microbe-drug associations can be predicted with considerable utility. Deep learning-based techniques have recently found widespread use in the biomedical industry and have significantly impro…
View article: Hyaluronic acid modified carbon nanotubes using for photothermal therapy by promoting apoptosis of nasopharyngeal carcinoma cells
Hyaluronic acid modified carbon nanotubes using for photothermal therapy by promoting apoptosis of nasopharyngeal carcinoma cells Open
Background: The present work illustrates the role of multi-walled carbon nanotubes in photothermal therapy. Nasopharyngeal carcinoma (NPC) is a malignant tumor of the head and neck with significant ethnic and geographic differences, and co…
View article: National Brain Tumour Registry of China (NBTRC) statistical report of primary brain tumours diagnosed in China in years 2019–2020
National Brain Tumour Registry of China (NBTRC) statistical report of primary brain tumours diagnosed in China in years 2019–2020 Open
The National Key Research and Development Program of China (2015BAI12B04, 2013BAI09B03, 2014BAI04B01, and 2021YFF1201104) and Chinese National Natural Science Foundation of China (81971668).
View article: Antiplatelet therapy adjustment improved the radiomic characteristics of acute silent cerebral infarction after stent-assisted coiling in patients with high on-treatment platelet reactivity: A prospective study
Antiplatelet therapy adjustment improved the radiomic characteristics of acute silent cerebral infarction after stent-assisted coiling in patients with high on-treatment platelet reactivity: A prospective study Open
Background We aimed to investigate the effects of high on-treatment platelet reactivity (HPR) and antiplatelet therapy adjustment on high-risk radiomic features in patients with antiplatelet therapy adjustment on acute silent cerebral infa…
View article: Circular RNA circFAT1(e2) Facilitates Cell Progression through the miR-30e-5P/MYBL2 Pathway in Glioma
Circular RNA circFAT1(e2) Facilitates Cell Progression through the miR-30e-5P/MYBL2 Pathway in Glioma Open
Objective. To explore the mechanism of glioma from MYB family genes from the perspective of the circRNA-miRNA-mRNA regulatory network. Methods. First, the MYB family genes were analyzed by multiple bioinformatics analyses to identify one g…
View article: The new oncogene transmembrane protein 60 is a potential therapeutic target in glioma
The new oncogene transmembrane protein 60 is a potential therapeutic target in glioma Open
Glioma is a malignant tumor with a high fatality rate, originating in the central nervous system. Even after standard treatment, the prognosis remains unsatisfactory, probably due to the lack of effective therapeutic targets. The family of…
View article: Integrated transcriptome and plant growth substance profiles to identify the regulatory factors involved in floral sex differentiation in Zanthoxylum armatum DC
Integrated transcriptome and plant growth substance profiles to identify the regulatory factors involved in floral sex differentiation in Zanthoxylum armatum DC Open
Zanthoxylum armatum is a prominent plant for food industries. Its male flowers often occur in gynogenesis plants; however, the potential mechanism remains poorly understood. Herein, a total of 26 floral sex differentiation stages were obse…
View article: Responses of Antioxidant Enzyme Activity to Different Fertilizer and Soil Moisture Conditions in Relation to Cold Resistance in Zanthoxylum armatum
Responses of Antioxidant Enzyme Activity to Different Fertilizer and Soil Moisture Conditions in Relation to Cold Resistance in Zanthoxylum armatum Open
Zanthoxylum armatum, known as green prickly ash, is a major condiment species planted on a large scale in southwest China. However, its limited cold tolerance has been a significant disadvantage for its cultivation in low-temperature regio…
View article: Combinations of Single-Gene Biomarkers Can Precisely Stratify 1,028 Adult Gliomas for Prognostication
Combinations of Single-Gene Biomarkers Can Precisely Stratify 1,028 Adult Gliomas for Prognostication Open
Advanced genomic techniques have now been incorporated into diagnostic practice in neuro-oncology in the literature. However, these assays are expensive and time-consuming and demand bioinformatics expertise for data interpretation. In con…
View article: Gastrin/CCK2R alleviates mucus barrier loss via β-arrestin1/NF-κBp65 signaling in ulcerative colitis.
Gastrin/CCK2R alleviates mucus barrier loss via β-arrestin1/NF-κBp65 signaling in ulcerative colitis. Open
Background and Purpose: The defective colonic mucus barrier is a feature of ulcerative colitis (UC) that enables increased bacterial contact with the epithelium, which triggers mucosal damage, and gastrin has been reported to be able to pr…
View article: Therapeutic Effects of Berberine on Liver Fibrosis are associated With Lipid Metabolism and Intestinal Flora
Therapeutic Effects of Berberine on Liver Fibrosis are associated With Lipid Metabolism and Intestinal Flora Open
Liver cirrhosis is a form of liver fibrosis resulting from chronic hepatitis caused by various liver diseases, such as viral hepatitis, alcoholic liver damage, nonalcoholic steatohepatitis , autoimmune liver disease, and by parasitic disea…