Xiaohu Li
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View article: Neuro-regulatory biomaterials for IVD regeneration via neuro-disc microenvironment modulation
Neuro-regulatory biomaterials for IVD regeneration via neuro-disc microenvironment modulation Open
View article: Carotid DECTA in patients with dental hardware: Impact of deep learning image reconstruction and metal artifact reduction
Carotid DECTA in patients with dental hardware: Impact of deep learning image reconstruction and metal artifact reduction Open
View article: CAVGAN: Unifying Jailbreak and Defense of LLMs via Generative Adversarial Attacks on their Internal Representations
CAVGAN: Unifying Jailbreak and Defense of LLMs via Generative Adversarial Attacks on their Internal Representations Open
Security alignment enables the Large Language Model (LLM) to gain the protection against malicious queries, but various jailbreak attack methods reveal the vulnerability of this security mechanism. Previous studies have isolated LLM jailbr…
View article: Spatial heterogeneity of landslide distribution and its drivers in the Yangtze River Basin: a remote sensing and GIS-based multi-factor analysis
Spatial heterogeneity of landslide distribution and its drivers in the Yangtze River Basin: a remote sensing and GIS-based multi-factor analysis Open
Introduction The Yangtze River Basin (YRB) is a region of immense economic and ecological significance in China, whose complex topography and climatic variability render it particularly susceptible to landslide disasters. Methods In this s…
View article: A three-classification machine learning model for non-invasive prediction of molecular subtypes in diffuse glioma: a two-center study
A three-classification machine learning model for non-invasive prediction of molecular subtypes in diffuse glioma: a two-center study Open
Our study constructed a three-classification ML model that combined CM features, RSTD features, and demographic characteristics, achieved promising performance in predicting molecular subtypes of diffuse glioma. The combined model provided…
View article: Increased CCL18 expression infers a poor prognosis in glioblastoma multiforme and promotes U-87 MG cell proliferation and migration: A retrospective cohort study
Increased CCL18 expression infers a poor prognosis in glioblastoma multiforme and promotes U-87 MG cell proliferation and migration: A retrospective cohort study Open
This study aims to investigate the role of C-C Motif Chemokine Ligand 18 (CCL18) in glioblastoma multiforme tissues. Glioblastoma multiforme-related gene expression, clinical parameters, and the corresponding expression data in normal tiss…
View article: Surface‐Bound Gene‐Functionalized Injectable Short Fibers via Reversing Collagen Aging for Inhibiting Intervertebral Disc Degeneration
Surface‐Bound Gene‐Functionalized Injectable Short Fibers via Reversing Collagen Aging for Inhibiting Intervertebral Disc Degeneration Open
Collagen aging, which results from senescent nucleus pulposus (NP) cells, is a key factor in intervertebral disc degeneration (IDD). Traditional therapies that target the removal of senescent cells fail to address the underlying problem of…
View article: Diagnosis and risk stratification of PI-RADS v2.1 category 3–5 lesions using amide proton transfer imaging
Diagnosis and risk stratification of PI-RADS v2.1 category 3–5 lesions using amide proton transfer imaging Open
In PI-RADS v2.1 category 3-5 lesions, APT can serve as an important biomarker for the risk stratification of PCa, and combining APT with PSAD and ADC achieves the highest diagnostic efficacy.
View article: CAVGAN: Unifying Jailbreak and Defense of LLMs via Generative Adversarial Attacks on their Internal Representations
CAVGAN: Unifying Jailbreak and Defense of LLMs via Generative Adversarial Attacks on their Internal Representations Open
View article: Artificial Intelligence Applications in Fangcang Shelter Hospitals: Opportunities and Challenges
Artificial Intelligence Applications in Fangcang Shelter Hospitals: Opportunities and Challenges Open
Fangcang shelter hospitals are modular, rapidly deployable facilities that play a vital role in pandemic response by providing centralized isolation and basic medical care for large patient populations. Artificial intelligence (AI) has the…
View article: A Uav-Based Multi-Defect Real-Time Detection System for Tunnel Lining Using Attention Mechanism-Enhanced Detection Model
A Uav-Based Multi-Defect Real-Time Detection System for Tunnel Lining Using Attention Mechanism-Enhanced Detection Model Open
View article: Barlow and Proschan principle for coherent systems with statistically dependent component and redundancy lifetimes
Barlow and Proschan principle for coherent systems with statistically dependent component and redundancy lifetimes Open
For coherent systems with components and active redundancies having heterogeneous and dependent lifetimes, we prove that the lifetime of system with redundancy at component level is stochastically larger than that with redundancy at system…
View article: Biomaterial-based circular RNA therapeutic strategy for repairing intervertebral disc degeneration
Biomaterial-based circular RNA therapeutic strategy for repairing intervertebral disc degeneration Open
Intervertebral disc degeneration (IDD) is the leading cause of low-back pain, which brings huge threaten to patients' life and workability. However, IDD's pathophysiology is still a puzzle, thus conventional conservative therapy leads to l…
View article: Predicting solitary pulmonary lesions in breast cancer patients using 18Fluorodeoxyglucose-positron emission tomography/computed tomography
Predicting solitary pulmonary lesions in breast cancer patients using 18Fluorodeoxyglucose-positron emission tomography/computed tomography Open
Background Solitary pulmonary nodules (SPNs) remain difficult to diagnose for clinical therapeutic purposes in patients with a history of breast cancer. This study try to investigate the value of 18F-fluorodeoxyglucose (18<…
View article: Biomimetic Microstructural Materials for Intervertebral Disk Degeneration Repair
Biomimetic Microstructural Materials for Intervertebral Disk Degeneration Repair Open
The intervertebral disks (IVD) serve as shock absorbers in the spine. As the largest avascular tissue in the human body, it has a limited capacity for regeneration. To address this issue, various innovative biomimetic materials have been e…
View article: Diagnosis and Risk Stratification of PI-RADS v2.1 Category 3–5 Lesions Using Amide Proton Transfer Imaging
Diagnosis and Risk Stratification of PI-RADS v2.1 Category 3–5 Lesions Using Amide Proton Transfer Imaging Open
Objectives: To explore the value of amide proton transfer-weighted imaging (APTWI) combined with apparent diffusion coefficient (ADC) and prostate-specific antigen density (PSAD) in evaluating the risk of aggressive PI-RADS v2.1 category 3…
View article: Application of Dynamic [18F]-FDG PET/CT Multiparametric Imaging Leads to an Improved Differentiation of Benign and Malignant Lung Lesions
Application of Dynamic [18F]-FDG PET/CT Multiparametric Imaging Leads to an Improved Differentiation of Benign and Malignant Lung Lesions Open
Purpose To evaluate the potential of whole-body dynamic (WBD) 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography ([18F]-FDG PET/CT) multiparametric imaging in the differential diagnosis b…
View article: Progress of Gene‐Functionalized Regenerative Material Repair Intervertebral Disc Degeneration
Progress of Gene‐Functionalized Regenerative Material Repair Intervertebral Disc Degeneration Open
Intervertebral disc degeneration (IDD) is widely recognized as the primary culprit of chronic low back pain. Restoring deteriorated intervertebral disc (IVD) and alleviating IDD‐induced low back pain are remaining enormous challenges. Ther…
View article: Editorial: Regulatory immune cells in organ transplantation
Editorial: Regulatory immune cells in organ transplantation Open
Keywords: regulatory immune cells, organ transplantation, tolerance, immunosuppression, immune response
View article: Identification of a novel glioblastoma multiforme molecular subtype with poor prognosis and high immune infiltration based on oxidative stress-related genes
Identification of a novel glioblastoma multiforme molecular subtype with poor prognosis and high immune infiltration based on oxidative stress-related genes Open
Glioblastoma multiforme (GBM) is a highly malignant primary brain tumor with a poor prognosis. Reactive oxygen species that accumulate during tumorigenesis can cause oxidative stress (OS), which plays a crucial role in cancer cell survival…
View article: Manipulate the Electronic Properties of the (100) Surface of Srtio3 for Photocatalytic Hydrogen Evolution Reaction
Manipulate the Electronic Properties of the (100) Surface of Srtio3 for Photocatalytic Hydrogen Evolution Reaction Open
View article: Clinical manifestations and MRI features of Danon disease: a case series
Clinical manifestations and MRI features of Danon disease: a case series Open
View article: ClinicalGPT: Large Language Models Finetuned with Diverse Medical Data and Comprehensive Evaluation
ClinicalGPT: Large Language Models Finetuned with Diverse Medical Data and Comprehensive Evaluation Open
Large language models have exhibited exceptional performance on various Natural Language Processing (NLP) tasks, leveraging techniques such as the pre-training, and instruction fine-tuning. Despite these advances, their effectiveness in me…
View article: 3D whole-heart noncontrast coronary MR angiography based on compressed SENSE technology: a comparative study of conventional SENSE sequence and coronary computed tomography angiography
3D whole-heart noncontrast coronary MR angiography based on compressed SENSE technology: a comparative study of conventional SENSE sequence and coronary computed tomography angiography Open
View article: Design and Implementation of Local Resonance Milling Tools for Chatter Suppression
Design and Implementation of Local Resonance Milling Tools for Chatter Suppression Open
View article: Sirtuin-1 attenuates cadmium-induced renal cell senescence through p53 deacetylation
Sirtuin-1 attenuates cadmium-induced renal cell senescence through p53 deacetylation Open
Cadmium (Cd), the common environmental pollutant, primarily targets at renal proximal tubules and induces nephrotoxicity. Cellular senescence, a phenomenon of cell growth arrest and a characteristics of maladaptive cell self-repair, is ass…
View article: A CT-based nomogram for predicting the risk of adenocarcinomas in patients with subsolid nodule according to the 2021 WHO classification
A CT-based nomogram for predicting the risk of adenocarcinomas in patients with subsolid nodule according to the 2021 WHO classification Open
View article: Two-stage hybrid network for segmentation of COVID-19 pneumonia lesions in CT images: a multicenter study
Two-stage hybrid network for segmentation of COVID-19 pneumonia lesions in CT images: a multicenter study Open
View article: Multimodality imaging in cardiac myxofibrosarcoma
Multimodality imaging in cardiac myxofibrosarcoma Open
View article: 东太平洋CCFZ区多金属结核元素富集机制：来自结核剖面原位微区分析
东太平洋CCFZ区多金属结核元素富集机制：来自结核剖面原位微区分析 Open
摘要: 多金属结核微层原位微区分析能够更好地揭示结核生长过程中元素的赋存和迁移过程，为认识多金属结核元素富集机制和成因提供新的证据.通过使用电子探针（EPMA）和激光剥蚀电感耦合等离子体质谱（LA-ICP-MS）等手段对采集自东太平洋克拉里昂-克利珀顿断裂区（CCFZ区）的多金属结核进行了分析研究.研究结果表明，结核矿物主要为水羟锰矿、10Å锰矿和FeOOH，锰铁矿物圈层由内而外可划分为4个明显的层组：L1、L2、L3和L4，Mn和Fe的平均含量分别为32.2和13.3%、…