Xiaohui Bai
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View article: Chromosome-level genome assembly of Amur Minnow (Rhynchocypris lagowskii)
Chromosome-level genome assembly of Amur Minnow (Rhynchocypris lagowskii) Open
Amur minnow (Rhynchocypris lagowskii), an economically important freshwater fish, inhabits tributaries of the Heilongjiang River to Yangtze River in China. Thus far, no genome data of this species have been reported. In this study, we cons…
View article: Mechanisms Behind the Formation of Ellipsoid Eggs in Silk-Worms (<em>Bombyx mori</em>): Insights from Transcriptomic Profiling
Mechanisms Behind the Formation of Ellipsoid Eggs in Silk-Worms (<em>Bombyx mori</em>): Insights from Transcriptomic Profiling Open
Background/Objectives: The elongated egg is a morphological mutant of silkworm (Bombyx mori) eggs, yet the biochemical processes and molecular mechanisms underlying this trait remain unclear. Methods: In this study, we performed transcript…
View article: Melanin pathway genes drive skin color divergence in juvenile blood parrot cichlid hybrids
Melanin pathway genes drive skin color divergence in juvenile blood parrot cichlid hybrids Open
The blood parrot cichlid (Cichlasoma citrinellum × C. synspilum), a hybrid of two distinct cichlid fish, is a popular ornamental fish. Its red appearance, achieved through its initial black coloration fading three weeks after hatching, is …
View article: Exploration of the Impact of Ovarian Sex Cord-Stromal Tumor (SCST) Classification on Diagnostic Coding
Exploration of the Impact of Ovarian Sex Cord-Stromal Tumor (SCST) Classification on Diagnostic Coding Open
Ovarian sex cord-stromal tumors (SCSTs) are relatively rare with numerous subtypes, making preoperative diagnosis difficult. Treatment plans should be individualized based on pathological types. In practice, diagnostic coding errors freque…
View article: Matrix metalloproteinases as diagnostic and prognostic biomarkers in skin cutaneous melanoma and squamous cell carcinoma
Matrix metalloproteinases as diagnostic and prognostic biomarkers in skin cutaneous melanoma and squamous cell carcinoma Open
Skin cutaneous melanoma (SKCM) and squamous cell carcinoma (SCC) are two prevalent forms of skin cancer, both characterized by extensive remodeling of the extracellular matrix (ECM), which facilitates tumor progression and metastasis. To i…
View article: Identification of Salt Marsh Vegetation in the Yellow River Delta Using UAV Multispectral Imagery and Deep Learning
Identification of Salt Marsh Vegetation in the Yellow River Delta Using UAV Multispectral Imagery and Deep Learning Open
Salt marsh ecosystems play a critical role in coastal protection, carbon sequestration, and biodiversity preservation. However, they are increasingly threatened by climate change and anthropogenic activities, necessitating precise vegetati…
View article: Transcriptome Analysis Reveals the Immunosuppression in Chinese Mitten Crab (Eriocheir Sinensis) Under Metschnikowia Bicuspidate Infection
Transcriptome Analysis Reveals the Immunosuppression in Chinese Mitten Crab (Eriocheir Sinensis) Under Metschnikowia Bicuspidate Infection Open
View article: The Delamination of the Tearing Indian Continental Lithosphere Triggered the Eruption and Mineralization of the Miocene Adakitic Magma in Gangdese: Insights from Demingding Cu-Mo Deposit
The Delamination of the Tearing Indian Continental Lithosphere Triggered the Eruption and Mineralization of the Miocene Adakitic Magma in Gangdese: Insights from Demingding Cu-Mo Deposit Open
View article: Transcriptome Analysis Reveals the Immunosuppression in Chinese Mitten Crab (Eriocheir Sinensis) Under Metschnikowia Bicuspidate Infection
Transcriptome Analysis Reveals the Immunosuppression in Chinese Mitten Crab (Eriocheir Sinensis) Under Metschnikowia Bicuspidate Infection Open
View article: Effects of Yeast Culture and Yeast Cell Wall Polysaccharide on Intestinal Barrier Function in Mongolian Ram Lambs
Effects of Yeast Culture and Yeast Cell Wall Polysaccharide on Intestinal Barrier Function in Mongolian Ram Lambs Open
View article: Transcriptome Analysis Reveals the Immunosuppression in Chinese Mitten Crab (Eriocheir Sinensis) Under Metschnikowia Bicuspidate Infection
Transcriptome Analysis Reveals the Immunosuppression in Chinese Mitten Crab (Eriocheir Sinensis) Under Metschnikowia Bicuspidate Infection Open
View article: Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stress
Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stress Open
Background Recurrent abdominal pain (RAP) is one of the most common gastrointestinal disorders in children. The aim of this study was to investigate the relationship between RAP and Helicobacter pylori infection in children in Wuhu, China …
View article: Enhancing Renal Autophagy via Yangshen Paidu Decoction: AMPK/mTOR Pathway Modulation in Chronic Renal Failure Management
Enhancing Renal Autophagy via Yangshen Paidu Decoction: AMPK/mTOR Pathway Modulation in Chronic Renal Failure Management Open
Objective: Chronic Renal Failure (CRF) refers to the gradual decline in renal function caused by various chronic kidney diseases, eventually leading to end-stage renal failure. Yangshen Paidu Decoction (YPD) is a Traditional Chinese medici…
View article: Aquaculture Ponds Identification Based on Multi-Feature Combination Strategy and Machine Learning from Landsat-5/8 in a Typical Inland Lake of China
Aquaculture Ponds Identification Based on Multi-Feature Combination Strategy and Machine Learning from Landsat-5/8 in a Typical Inland Lake of China Open
Inland aquaculture ponds, as an important land use type, have brought great economic benefits to local people but at the same time have caused many environmental problems threatening regional ecology security. Therefore, understanding the …
View article: Lung Transplant Immunomodulation with Genetically Engineered Mesenchymal Stromal Cells—Therapeutic Window for Interleukin-10
Lung Transplant Immunomodulation with Genetically Engineered Mesenchymal Stromal Cells—Therapeutic Window for Interleukin-10 Open
Lung transplantation results are compromised by ischemia–reperfusion injury and alloimmune responses. Ex vivo lung perfusion (EVLP) is used to assess marginal donor lungs before transplantation but is also an excellent platform to apply no…
View article: Two Genotypes of Streptococcus iniae Are the Causative Agents of Diseased Ornamental Fish, Green Terror Cichlid (Aequidens rivulatus)
Two Genotypes of Streptococcus iniae Are the Causative Agents of Diseased Ornamental Fish, Green Terror Cichlid (Aequidens rivulatus) Open
Green terror cichlid (Aequidens rivulatus) is a popular tropical freshwater ornamental fish. In 2021, an unknown disease was observed in cultured A. rivulatus in Tianjin, China, with a cumulative mortality rate of 25% within 7 days of onse…
View article: 4‐octyl itaconate alleviates cisplatin‐induced ferroptosis possibly via activating the <scp>NRF2</scp>/<scp>HO</scp>‐1 signalling pathway
4‐octyl itaconate alleviates cisplatin‐induced ferroptosis possibly via activating the <span>NRF2</span>/<span>HO</span>‐1 signalling pathway Open
Ferroptosis, characterized by iron‐dependent lipid reactive oxygen species (ROS) accumulation, plays a pivotal role in cisplatin‐induced ototoxicity. Existing research has suggested that in cisplatin‐mediated damage to auditory cells and h…
View article: A meta-analysis comparing the efficacy of mineralized collagen-polymethylmethacrylate and polymethylmethacrylate bone cements in the treatment of vertebral compression fractures
A meta-analysis comparing the efficacy of mineralized collagen-polymethylmethacrylate and polymethylmethacrylate bone cements in the treatment of vertebral compression fractures Open
Purpose Vertebral compression fractures are often treated with vertebroplasty, and filling the injured vertebrae with bone cement is a key part of vertebroplasty. This meta-analysis was performed to compare the clinical efficacy and safety…
View article: Bacterial Microbiome Differences between the Roots of Diseased and Healthy Chinese Hickory (<i>Carya cathayensis</i>) Trees
Bacterial Microbiome Differences between the Roots of Diseased and Healthy Chinese Hickory (<i>Carya cathayensis</i>) Trees Open
Carya cathayensis is an important economic nut tree that is endemic to eastern China. As such, outbreaks of root rot disease in C. cathayensis result in reduced yields and serious economic losses. Moreover, while soil bacteri…
View article: Identification of Mycobacterium chelonae from Lined Seahorse Hippocampus erectus and Histopathological Analysis
Identification of Mycobacterium chelonae from Lined Seahorse Hippocampus erectus and Histopathological Analysis Open
The lined seahorse (Hippocampus erectus) is an aquacultural species in China and has important economic and ornamental value. However, the species is affected by disease, which restricts their large-scale cultivation. In 2021, a disease wa…
View article: TCS01 Two-Component System Influenced the Virulence of Streptococcus pneumoniae by Regulating PcpA
TCS01 Two-Component System Influenced the Virulence of Streptococcus pneumoniae by Regulating PcpA Open
Streptococcus pneumoniae relies on two-component systems (TCSs) to regulate the processes of pathogenicity, osmotic pressure, chemotaxis, and energy metabolism. The TCS01 system of S. pneumoniae is composed of HK01 (histidine kinase) and R…
View article: Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway
Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway Open
Background Mutations in lipoxygenase homology domain 1 ( LOXHD1 ) cause autosomal recessive inheritance, leading to high-frequency and intermediate-frequency hearing losses in patients. To date, studies on the localization of LOXHD1 gene e…
View article: Identification of a novel AIFM1 variant from a Chinese family with auditory neuropathy
Identification of a novel AIFM1 variant from a Chinese family with auditory neuropathy Open
Background: Auditory neuropathy (AN) is a specific type of hearing loss characterized by impaired language comprehension. Apoptosis inducing factor mitochondrion associated 1 ( AIFM1 ) is the most common gene associated with late-onset AN.…
View article: Advancements in the Studies of Novel Nanomaterials for Inner Ear Drug Delivery
Advancements in the Studies of Novel Nanomaterials for Inner Ear Drug Delivery Open
Hearing loss is currently one of the most prevalent sensory disorders worldwide. Because both the blood-labyrinth barrier and the limited blood circulation in the inner ear restrain the effective delivery of most drugs to the inner ear tis…
View article: Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer’s disease revealed by weighted gene co-expression network analysis
Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer’s disease revealed by weighted gene co-expression network analysis Open
View article: Effects of β-Carotin and Green Tea Powder Diets on Alleviating the Symptoms of Gouty Arthritis and Improving Gut Microbiota in C57BL/6 Mice
Effects of β-Carotin and Green Tea Powder Diets on Alleviating the Symptoms of Gouty Arthritis and Improving Gut Microbiota in C57BL/6 Mice Open
As a chronic metabolic disease caused by disorders of purine metabolism, gout has shown increasing incidence rate worldwide. Considering that gout is not easily treated and cured, further studies are explored to prevent gout development th…
View article: 4‐octyl Itaconate inhibits lipopolysaccharide (LPS)‐induced osteoarthritis via activating Nrf2 signalling pathway
4‐octyl Itaconate inhibits lipopolysaccharide (LPS)‐induced osteoarthritis via activating Nrf2 signalling pathway Open
Small molecule drug intervention for chondrocytes is a valuable method for the treatment of osteoarthritis (OA). The 4‐octyl itaconate (OI) is a cellular derivative of itaconate with sound cell permeability and transformation rate. We atte…
View article: Additional file 9 of Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer’s disease revealed by weighted gene co-expression network analysis
Additional file 9 of Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer’s disease revealed by weighted gene co-expression network analysis Open
Additional file 9: Table S5. GO analysis diagram of hub genes.
View article: Additional file 8 of Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer’s disease revealed by weighted gene co-expression network analysis
Additional file 8 of Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer’s disease revealed by weighted gene co-expression network analysis Open
Additional file 8: Table S4. Module info of WGCNA analysis.
View article: Highly Efficient Simultaneous Hydrogen Evolution and Organic Pollutants Removal Using CDS Decorated with Cop Nanosheet Under Visible Light
Highly Efficient Simultaneous Hydrogen Evolution and Organic Pollutants Removal Using CDS Decorated with Cop Nanosheet Under Visible Light Open