Xiaojie Wang
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View article: Alterations in gut microbiota and plasma metabolites: a multi-omics study of mild cognitive impairment in Parkinson’s disease
Alterations in gut microbiota and plasma metabolites: a multi-omics study of mild cognitive impairment in Parkinson’s disease Open
Introduction Emerging evidence suggests that gut microbiota and plasma metabolites may be associated with the onset and progression of Parkinson’s disease (PD). The interplay between gut microbiota and plasma metabolites in influencing the…
View article: Multiwavelength study of Galactic PeVatron LHAASO J0341+5258
Multiwavelength study of Galactic PeVatron LHAASO J0341+5258 Open
View article: Depression and health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies
Depression and health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies Open
Background Currently, most studies of depression are limited to a single disease endpoint. Aims This study aimed to conduct an umbrella review to comprehensively assess the association between depression and health outcomes. Method Until D…
View article: Experimental Study on the Activation Mechanism of Residual Slag Micro Powder After Recycled Aggregate of Waste Concrete
Experimental Study on the Activation Mechanism of Residual Slag Micro Powder After Recycled Aggregate of Waste Concrete Open
This study investigated sustainable activation strategies for residual slag micro powder derived from recycled waste concrete aggregates, aiming to advance circular economy principles in construction materials. An experimental study was ca…
View article: Correction: Comparison of different surgical techniques and anastomosis methods in short-term outcomes of right colon cancer: a network meta-analysis of open surgery, laparoscopic, and robot-assisted techniques with extracorporeal and intracorporeal anastomosis
Correction: Comparison of different surgical techniques and anastomosis methods in short-term outcomes of right colon cancer: a network meta-analysis of open surgery, laparoscopic, and robot-assisted techniques with extracorporeal and intracorporeal anastomosis Open
View article: Feeding selectivity of Holotrichia oblita and the effect of arachidonic acid on its feeding and fecundity
Feeding selectivity of Holotrichia oblita and the effect of arachidonic acid on its feeding and fecundity Open
Arachidonic acid affect the feeding and fecundity of H. oblita .
View article: Systemic inflammatory biomarkers as mediators of the association between dietary flavonoids and sleep disorders in patients with hypertension: A population-based study
Systemic inflammatory biomarkers as mediators of the association between dietary flavonoids and sleep disorders in patients with hypertension: A population-based study Open
View article: Validation of Senescence of the Role of ATM/P53 Pathway in Myocardial Senescence in Mice with Sepsis
Validation of Senescence of the Role of ATM/P53 Pathway in Myocardial Senescence in Mice with Sepsis Open
Cellular senescence and immune dysregulation play critical roles in SIMD. Targeting DDR pathways, as demonstrated by KU60019 treatment, provides novel insights into the role of cellular senescence in severe sepsis and its potential therape…
View article: Risk factors for organ-space surgical site infections after minimally invasive rectal cancer surgery: a retrospective cohort study
Risk factors for organ-space surgical site infections after minimally invasive rectal cancer surgery: a retrospective cohort study Open
This study found that 5 risk factors (male gender, conversion to laparotomy, diabetes, CJP and TCP, and hand-sewn anastomosis) can be used to categorize the likelihood of postoperative organ-space SSI.
View article: PTEN: A Novel Diabetes Nephropathy Protective Gene Related to Cellular Senescence
PTEN: A Novel Diabetes Nephropathy Protective Gene Related to Cellular Senescence Open
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD). The current diagnostic and therapeutic approaches need to be improved. Cellular senescence has been implicated in the pathogenesis of DN, but its precise rol…
View article: Impact of surgical site infection on short- and long-term outcomes of robot-assisted rectal cancer surgery: a two-center retrospective study
Impact of surgical site infection on short- and long-term outcomes of robot-assisted rectal cancer surgery: a two-center retrospective study Open
View article: Robotic versus laparoscopic surgery for rectal cancer: an updated systematic review and meta-analysis of randomized controlled trials
Robotic versus laparoscopic surgery for rectal cancer: an updated systematic review and meta-analysis of randomized controlled trials Open
View article: A Device for the Removal of Peripheral Blood Circulating Tumor Cells and Inhibiting Their Biodistribution
A Device for the Removal of Peripheral Blood Circulating Tumor Cells and Inhibiting Their Biodistribution Open
Circulating tumor cells (CTCs) significantly impact the overall survival and progression-free survival of cancer patients. However, the current strategies for CTC separation and enrichment are limited as they analyze only small-volume bloo…
View article: Association between fibrinogen and cognitive impairment in patients with ischemic cerebrovascular disease
Association between fibrinogen and cognitive impairment in patients with ischemic cerebrovascular disease Open
Fibrinogen is associated with cognitive impairment among patients with ICVD, and significantly negatively impacts global cognitive function and visuospatial/executive function. Furthermore, the negative correlation between fibrinogen and N…
View article: Clinical, biological, and neuroimaging profiles for motoric cognitive risk syndrome in older adults: The MIND‐China study
Clinical, biological, and neuroimaging profiles for motoric cognitive risk syndrome in older adults: The MIND‐China study Open
Background Motoric cognitive risk syndrome (MCR) has been associated with dementia, functional dependence, and mortality. We sought to describe the prevalence and distribution of MCR and to explore the clinical, biological, and neuroimagin…
View article: Construction of the Single‐Cell Landscape of Hashimoto's Thyroiditis Tissue and Peripheral Blood by Single‐Cell RNA Sequencing
Construction of the Single‐Cell Landscape of Hashimoto's Thyroiditis Tissue and Peripheral Blood by Single‐Cell RNA Sequencing Open
Background Hashimoto's thyroiditis (HT) is the most common organ‐specific autoimmune disease, and its etiology may be related to genetic, environmental, and epigenetic factors. However, its exact pathogenesis remains elusive. Methods In th…
View article: Mediterranean diet and dementia: MRI marker evidence from meta-analysis
Mediterranean diet and dementia: MRI marker evidence from meta-analysis Open
Adherence to MeDi may be associated with reduced WMH in older adults. This suggests that MeDi may affect brain health and highlights the need for further research into its role as a modifiable lifestyle factor that might potentially modify…
View article: Development and Evaluation of the Immunogenic Potential of an Unmodified Nucleoside mRNA Vaccine for Herpes Zoster
Development and Evaluation of the Immunogenic Potential of an Unmodified Nucleoside mRNA Vaccine for Herpes Zoster Open
Background/Objectives: Approved mRNA vaccines commonly use sequences modified with pseudouridine to enhance translation efficiency and mRNA stability. However, this modification can result in ribosomal frameshifts, reduced immunogenicity, …
View article: CoTD-PO: Chain-of-Thought Distillation with Preference Optimization
CoTD-PO: Chain-of-Thought Distillation with Preference Optimization Open
View article: Single‐Cell Insights Into Cellular Response in Abdominal Aortic Occlusion‐Induced Hippocampal Injury
Single‐Cell Insights Into Cellular Response in Abdominal Aortic Occlusion‐Induced Hippocampal Injury Open
Objective Ischemia–reperfusion of the abdominal aorta often results in damage to distant organs, such as the heart and brain. This cellular heterogeneity within affected tissues complicates the roles of specific cell subsets in abdominal a…
View article: Case report: A rare case of malignant solitary fibrous tumor within the joint cavity with review of the literature
Case report: A rare case of malignant solitary fibrous tumor within the joint cavity with review of the literature Open
Solitary fibrous tumors (SFTs) are classified as fibroblastic/myofibroblastic tumors that originate from CD34-positive dendritic cells and usually occur in the pleura. In this paper, we describe a case of SFT within the joint cavity of the…
View article: Activation of P2X7 Receptor Mediates the Abnormal Ovulation Induced by Chronic Restraint Stress and Chronic Cold Stress
Activation of P2X7 Receptor Mediates the Abnormal Ovulation Induced by Chronic Restraint Stress and Chronic Cold Stress Open
Chronic stress has become a major problem that endangers people’s physical and mental health. Studies have shown that chronic stress impairs female reproduction. However, the related mechanism is not fully understood. P2X7 receptor (P2X7R)…
View article: Correlation between serum uric acid level and atrial fibrillation in patients with hyperthyroidism on medical data analysis context of IoT
Correlation between serum uric acid level and atrial fibrillation in patients with hyperthyroidism on medical data analysis context of IoT Open
BACKGROUND: Dysfunctions in metabolism and endocrine systems are outcomes of disruptions in human physiological processes, often leading to disease onset. External factors can hinder the human body’s innate capacity for self-regulation and…
View article: The biomedical knowledge graph of symptom phenotype in coronary artery plaque: machine learning-based analysis of real-world clinical data
The biomedical knowledge graph of symptom phenotype in coronary artery plaque: machine learning-based analysis of real-world clinical data Open
A knowledge graph can effectively showcase the essential characteristics of data and is increasingly emerging as a significant means of integrating information in the field of artificial intelligence. Coronary artery plaque represents a si…
View article: Safety and efficacy of indocyanine green fluorescence imaging-guided laparoscopic para-aortic lymphadenectomy for left-sided colorectal cancer: Preliminary results of a case-matched study
Safety and efficacy of indocyanine green fluorescence imaging-guided laparoscopic para-aortic lymphadenectomy for left-sided colorectal cancer: Preliminary results of a case-matched study Open
ICG fluorescence imaging could increase the retrieval of IMALN, PALN, and total lymph nodes, and potentially improve the completeness of laparoscopic PALN dissection in patients with left-sided CRC.
View article: Unraveling variations and enhancing prediction of successful sphincter-preserving resection for low rectal cancer: a post hoc analysis of the multicentre LASRE randomized clinical trial
Unraveling variations and enhancing prediction of successful sphincter-preserving resection for low rectal cancer: a post hoc analysis of the multicentre LASRE randomized clinical trial Open
Background: Accurate prediction of successful sphincter-preserving resection (SSPR) for low rectal cancer enables peer institutions to scrutinize their own performance and potentially avoid unnecessary permanent colostomy. The aim of this …
View article: Exploring the behavioral intentions of PICC-related thrombosis prevention in breast cancer patients undergoing chemotherapy: a qualitative study based on theory of planned behavior
Exploring the behavioral intentions of PICC-related thrombosis prevention in breast cancer patients undergoing chemotherapy: a qualitative study based on theory of planned behavior Open
Purpose To explores the behavioral intention of breast cancer patients undergoing chemotherapy to prevent PICC-related thrombosis based on the Theory of Planned Behavior. Methods This qualitative study employed purposive sampling and condu…
View article: The impact of high-altitude and cold environment on brain and heart damage in rats with hemorrhagic shock
The impact of high-altitude and cold environment on brain and heart damage in rats with hemorrhagic shock Open
BACKGROUND: Hemorrhagic shock (HS) causes severe organ damage, worsened by high-altitude conditions with lower oxygen and temperatures. Existing research lacks specific insights on brain and heart damage under these conditions. This study …
View article: Prenatal delta-9-tetrahydrocannabinol exposure alters fetal neurodevelopment in rhesus macaques
Prenatal delta-9-tetrahydrocannabinol exposure alters fetal neurodevelopment in rhesus macaques Open
Prenatal cannabis use is associated with adverse offspring neurodevelopmental outcomes, however the underlying mechanisms are relatively unknown. We sought to determine the impact of chronic delta-9-tetrahydrocannabinol (THC) exposure on f…
View article: The role of mitochondrial DNA copy number in cardiometabolic disease: a bidirectional two-sample mendelian randomization study
The role of mitochondrial DNA copy number in cardiometabolic disease: a bidirectional two-sample mendelian randomization study Open