Xiaojing Bao
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View article: Multiple ASXL1 mutations and G646fs alterations confer increased risk of leukemic Transformation in patients with myelofibrosis
Multiple ASXL1 mutations and G646fs alterations confer increased risk of leukemic Transformation in patients with myelofibrosis Open
Introduction The epigenetic regulator additional sex combs-like 1 (ASXL1) is the most commonly mutated high molecular risk gene in myleloid neoplasms and is associated with inferior clinical outcomes. Although the adverse prognostic value …
View article: Integrating clinical features, long-term Outcomes and NGS-based mutational analysis in AYA patients with essential Thrombocythemia and polycythemia vera: A Multicenter Retrosepective study
Integrating clinical features, long-term Outcomes and NGS-based mutational analysis in AYA patients with essential Thrombocythemia and polycythemia vera: A Multicenter Retrosepective study Open
Introduction: Essential thrombocythemia (ET) and polycythemia vera (PV) are myeloproliferative neoplasms (MPN) characterized by clonal thrombocytosis and erythrocytosis, had the risk of progression to myelofibrosis and acute myeloid leukem…
View article: Prognostic Implications of Red Blood Cell Distribution Width to Albumin Ratio in Myelofibrosis: A 10-Year Multicenter and Retrospective Study
Prognostic Implications of Red Blood Cell Distribution Width to Albumin Ratio in Myelofibrosis: A 10-Year Multicenter and Retrospective Study Open
This large, multi-center cohort study is the first to reveal the prognostic significance of RAR in MF. The modified predictive nomogram combining DIPSS-plus score and RAR enhances prognostic discrimination and calibration, providing a simp…
View article: HLA alleles, blocks, and haplotypes associated with the hematological diseases of AML, ALL, MDS, and AA in the Han population of Southeastern China
HLA alleles, blocks, and haplotypes associated with the hematological diseases of AML, ALL, MDS, and AA in the Han population of Southeastern China Open
View article: Intra- and early postoperative predictors of delirium risk in cardiac surgery
Intra- and early postoperative predictors of delirium risk in cardiac surgery Open
View article: The Value Research of Ideological and Political Education
The Value Research of Ideological and Political Education Open
Ideological and political education serves as a crucial avenue for instilling in students a correct world outlook, life perspective, and values. It constitutes a fundamental initiative in fostering profcient socialist contributors and succ…
View article: Posttransplant de novo DSA and NDSA affect GvHD, OS, and DFS after haplo-HSCT in patients without pre-existing HLA antibodies of hematological malignancies
Posttransplant de novo DSA and NDSA affect GvHD, OS, and DFS after haplo-HSCT in patients without pre-existing HLA antibodies of hematological malignancies Open
To examine the production time, type, and MFI of post-transplantation de novo HLA antibodies, and their effects on haplo-HSCT outcomes, we retrospectively included 116 patients who were negative for pre-existing HLA antibodies. In total, 3…
View article: Issue Information
Issue Information Open
View article: Dynamic mRNA expression of donor-derived activating KIR genes and their significant effects on clinical outcome after haematopoietic stem cell transplantation
Dynamic mRNA expression of donor-derived activating KIR genes and their significant effects on clinical outcome after haematopoietic stem cell transplantation Open
Numerous reports suggest that activating killer immunoglobulin-like receptors (aKIRs) of natural killer (NK) cells, in addition to inhibitory KIRs (iKIRs), play a prognostic role after allogeneic haematopoietic stem cell transplantation (a…
View article: Human leukocyte antigen (HLA) A-C-B-DRB1-DQB1 haplotype segregation analysis among 2152 families in China and the comparison to expectation-maximization algorithm result
Human leukocyte antigen (HLA) A-C-B-DRB1-DQB1 haplotype segregation analysis among 2152 families in China and the comparison to expectation-maximization algorithm result Open
Human leukocyte antigen (HLA) is the major histocompatibility complex for humans. Previous studies have shown that high-resolution HLA matching can reduce graft vs. host disease and improve the outcome of hematopoietic stem cell transplant…
View article: [Immune reconstruct regularity profile of KIR2DL1 and KIR3DL1 in unrelated-donor allogeneic hematopoietic stem cell transplantation].
[Immune reconstruct regularity profile of KIR2DL1 and KIR3DL1 in unrelated-donor allogeneic hematopoietic stem cell transplantation]. Open
Objective: To investigate the immune reconstruct regularity profile of KIR2DL1 and KIR3DL1 in unrelated-donor allogeneic hematopoietic stem cell transplantation (allo-HSCT) with KIR-AA genotype. Method: 75 donor-recipient pai…
View article: [Distribution of donor-specific aKIR after unrelated allogeneic hematopoietic stem cell transplantation].
[Distribution of donor-specific aKIR after unrelated allogeneic hematopoietic stem cell transplantation]. Open
Objective: To analyze the distribution and proportion of donor-specific activated killer cell immunoglobulin like receptor (aKIR) genes and their clinical application values in unrelated allogeneic hematopoietic stem cell transplant…
View article: [The role of different KIR haplotypes in haplo-identical hematopoietic stem cell transplantation].
[The role of different KIR haplotypes in haplo-identical hematopoietic stem cell transplantation]. Open
Overall, KIR genotyping and haplotype analyses should be useful for selection of the most optimal donors with favorable KIR gene grafts. KIR gene mismatch donors should be preferred for AML/MDS patients. Selecting donors carried Cen- B and…
View article: [Analysis of KIR3DL1 expression levels on 92 cases of normal donors for hematopoietic stem cells transplant].
[Analysis of KIR3DL1 expression levels on 92 cases of normal donors for hematopoietic stem cells transplant]. Open
The expression levels of KIR3DL1 in different KIR genotypes, haplotypes and HLA ligands were statistically significance.
View article: KIR2DS4 and Its Variant KIR1D Are Associated with Acute Graft-versus-Host Disease, Cytomegalovirus, and Overall Survival after Sibling-Related HLA-Matched Transplantation in Patients with Donors with KIR Gene Haplotype A
KIR2DS4 and Its Variant KIR1D Are Associated with Acute Graft-versus-Host Disease, Cytomegalovirus, and Overall Survival after Sibling-Related HLA-Matched Transplantation in Patients with Donors with KIR Gene Haplotype A Open
Outcomes for hematopoietic stem cell transplantation (HSCT) in various donor and recipient killer immunoglobulin-like receptor (KIR) genotypes have been studied extensively. The associations between KIR2DS4 and its variant KIR1D with outco…
View article: Donor Killer Immunoglobulin-Like Receptor Profile Bx1 Imparts a Negative Effect and Centromeric B-Specific Gene Motifs Render a Positive Effect on Standard-Risk Acute Myeloid Leukemia/Myelodysplastic Syndrome Patient Survival after Unrelated Donor Hematopoietic Stem Cell Transplantation
Donor Killer Immunoglobulin-Like Receptor Profile Bx1 Imparts a Negative Effect and Centromeric B-Specific Gene Motifs Render a Positive Effect on Standard-Risk Acute Myeloid Leukemia/Myelodysplastic Syndrome Patient Survival after Unrelated Donor Hematopoietic Stem Cell Transplantation Open
Donor killer immunoglobulin-like receptor (KIR) group B profiles (Bx) and homozygous of centromeric motif B (Cen-B/B) are the most preferable KIR gene content motifs for hematopoietic stem cell transplantation (HSCT). The risk of transplan…
View article: [Association of KIR2DS4 and its variant KIR1D with the outcome after HLA- identical sibling hematopoietic stem cell transplantation].
[Association of KIR2DS4 and its variant KIR1D with the outcome after HLA- identical sibling hematopoietic stem cell transplantation]. Open