Xiaoli Sheng
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View article: Celastrol loaded nanocomplex for painless tumor therapy via YAP inhibition
Celastrol loaded nanocomplex for painless tumor therapy via YAP inhibition Open
Cancer-related pain is prevalent and severely impairs patients' quality of life. However, conventional cancer therapies primarily target tumor cell destruction, often overlooking the management of cancer pain. Thus, there is an immediate n…
View article: Asymmetric Gradient Porous Fabric with Dynamically Tunable Thermal Management and Electromagnetic Interference Shielding via Delayed Phase Separation
Asymmetric Gradient Porous Fabric with Dynamically Tunable Thermal Management and Electromagnetic Interference Shielding via Delayed Phase Separation Open
The rapid development of global urbanization has exacerbated the urban heat island effect and electromagnetic radiation pollution. However, existing fabrics fail to provide both effective personal thermal management and electromagnetic int…
View article: Congenital Sternoclavicular Sinus—Case Series of a Rare Lower Neck Deformity
Congenital Sternoclavicular Sinus—Case Series of a Rare Lower Neck Deformity Open
Objectives We encountered patients with a congenital cutaneous sinus tract in the sternoclavicular joint region, which we designate as “congenital sternoclavicular sinus (CSCS).” The aim of this investigation is to enhance recognition of t…
View article: Enhanced catalytic activity and high stability of treated Pt-Ru/ zeolite Y catalysts for levulinic acid hydrogenation reaction
Enhanced catalytic activity and high stability of treated Pt-Ru/ zeolite Y catalysts for levulinic acid hydrogenation reaction Open
Bifunctional Pt-Ru/zeolite Y catalysts were prepared by ethylene glycol reduction (EGR) method, with 3 wt% of Pt and various ratios of Ru. The performance of catalysts was investigated for hydrogenation of levulinic acid (LA) to produce ga…
View article: [Clinical application of modified fistulectomy in the treatment of congenital pyriform sinus fistula based on segmental anatomy of fistula].
[Clinical application of modified fistulectomy in the treatment of congenital pyriform sinus fistula based on segmental anatomy of fistula]. Open
Objective:To discuss the clinical application and significance of the modified piriform fossa fistulectomy based on segmental anatomy of fistula. Methods:The clinical data of 84 patients with CPSF treated by modified pyriform sinus fistule…
View article: [The managements of cervical chondrocutaneous branchial remnants].
[The managements of cervical chondrocutaneous branchial remnants]. Open
Objective:To investigate the embryologic origin and diagnosis and management of cutaneous cartilage remains of gill origin in the neck. Methods:A total of 15 patients with cervical chondrocutaneous branchial remnants treated in Guangdong P…
View article: HTR7 promotes laryngeal cancer growth through PI3K/AKT pathway activation
HTR7 promotes laryngeal cancer growth through PI3K/AKT pathway activation Open
HTR7 is not only a target for laryngeal cancer therapy but also a prognostic factor for the prognosis of patients with laryngeal cancer.
View article: HTR7 Promotes Laryngeal Cancer Growth Through Activating PI3K/AKT Pathway
HTR7 Promotes Laryngeal Cancer Growth Through Activating PI3K/AKT Pathway Open
Background: Laryngeal cancer is a common malignancy of the head and neck, G protein-coupled receptors (GPCRs) are easily druggable in diseases. The 5-hydroxytryptamine receptor 7 (HTR7) belongs to the GPCR family; however, its role in lary…
View article: Upregulation of Long Noncoding RNA_GAS5 Suppresses Cell Proliferation and Metastasis in Laryngeal Cancer via Regulating PI3K/AKT/mTOR Signaling Pathway
Upregulation of Long Noncoding RNA_GAS5 Suppresses Cell Proliferation and Metastasis in Laryngeal Cancer via Regulating PI3K/AKT/mTOR Signaling Pathway Open
Background: Laryngeal cancer is one of the most common malignant tumors among head and neck cancers. Accumulating studies have indicated that long noncoding RNAs (lncRNAs) play an important role in laryngeal cancer occurrence and progressi…
View article: [Bilateral pyriform sinus fistulas: a case report].
[Bilateral pyriform sinus fistulas: a case report]. Open
A 6 year-old boy, who complained right neck abscesses and X-ray showed left pyriform fistula, was diagnosed as bilateral pyriform sinus fistulas. For bilateral pyriform sinus fistulas, endoscopic CO2laser cauterization should be the firs…
View article: Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy Open
Modeling SARS-CoV-2 in mice Among the research tools necessary to develop medical interventions to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, high on the list are informative animal models with which to …
View article: Lack of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, China
Lack of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, China Open
A woman with coronavirus disease in her 35th week of pregnancy delivered an infant by cesarean section in a negative-pressure operating room. The infant was negative for severe acute respiratory coronavirus 2. This case suggests that mothe…
View article: The prognostic value of tumor budding in laryngeal squamous cell carcinoma
The prognostic value of tumor budding in laryngeal squamous cell carcinoma Open
Tumor budding can be an independent factor of prognosis of LSCC patients and should be as a part of routine histopathologic report for LSCC cases.
View article: The Role of Insulin Glargine and Human Insulin in the Regulation of Thyroid Proliferation Through Mitogenic Signaling
The Role of Insulin Glargine and Human Insulin in the Regulation of Thyroid Proliferation Through Mitogenic Signaling Open
Our aim was to investigate whether human insulin (HI) or insulin glargine treatment could promote the proliferation of thyroid cells and determine the association between type 2 diabetes and thyroid disease. Rats were treated with differen…
View article: A Retrospective Study of The Prognostic Significance of Preoperative Plasma Fibrinogen, Mean Platelet Volume, and the Neutrophil-to-Lymphocyte Ratio in Patients with Laryngeal Squamous Cell Carcinoma
A Retrospective Study of The Prognostic Significance of Preoperative Plasma Fibrinogen, Mean Platelet Volume, and the Neutrophil-to-Lymphocyte Ratio in Patients with Laryngeal Squamous Cell Carcinoma Open
BACKGROUND This study aimed to evaluate the prognostic significance of plasma fibrinogen, serum albumin, the mean platelet volume (MPV), and the neutrophil-to-lymphocyte ratio (NLR) in patients with laryngeal squamous cell carcinoma (LSCC)…
View article: Marital status and survival of patients with kidney cancer
Marital status and survival of patients with kidney cancer Open
Our study revealed that marriage is associated with better outcomes of both OS and CSS in kidney cancer patients.