Xiaoqi Lin
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View article: Akkermansia muciniphila helps in the recovery of lipopolysaccharide-fed mice with mild intestinal dysfunction
Akkermansia muciniphila helps in the recovery of lipopolysaccharide-fed mice with mild intestinal dysfunction Open
Background Mild intestinal dysfunction, linked to subtle yet significant health issues, can be induced by lipopolysaccharide (LPS), a Gram-negative bacterial component that disrupts gut function and triggers inflammation. Akkermansia mucin…
View article: Tracer kinetic model detecting heterogeneous blood–brain barrier permeability to water and contrast agent in Alzheimer's disease and dementia with Lewy bodies
Tracer kinetic model detecting heterogeneous blood–brain barrier permeability to water and contrast agent in Alzheimer's disease and dementia with Lewy bodies Open
INTRODUCTION Blood–brain barrier (BBB) breakdown is essential in Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), whereas the variability in BBB permeability to water and contrast agent is less clear. METHODS We investigated B…
View article: Cytomorphology and clinicopathologic correlation of TFE3‐rearranged renal cell carcinoma
Cytomorphology and clinicopathologic correlation of TFE3‐rearranged renal cell carcinoma Open
Background TFE3 ‐rearranged renal cell carcinoma ( TFE3 ‐rRCC) harbors gene fusions involving TFE3 with one of many different partner genes. Because of their diverse morphologies, the differential diagnosis is broad and challenging. Public…
View article: ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway Open
ARPC1B emerges as an essential oncogenic factor in ccRCC by stimulating EMT and activating the Wnt/β-catenin pathway, ultimately enhancing tumor aggressiveness and metastatic potential. Thus, targeting ARPC1B represents a promising therape…
View article: <i>Blastocystis</i> load mediates the gut microbiome associations with within-host diversity of <i>Blastocystis</i> in non-human primates
<i>Blastocystis</i> load mediates the gut microbiome associations with within-host diversity of <i>Blastocystis</i> in non-human primates Open
Blastocystis is a prevalent gut eukaryote intricately associated with the gut microbiota. This genetically diverse protozoan exhibits significant intra-host subtype heterogeneity, yet the implications of this diversity for the host gut mic…
View article: Chromosome-level genome assembly of Indo-Pacific king mackerel (Scomberomorus guttatus)
Chromosome-level genome assembly of Indo-Pacific king mackerel (Scomberomorus guttatus) Open
The Indo-Pacific king mackerel, scientifically known as Scomberomorus guttatus, is a valued marine species that holds significant commercial importance in the Indo-Pacific region. However, the lack of genomic resources has hindered a compr…
View article: Molecular Pathogenesis of Renal Neoplasms in Patients with Birt–Hogg–Dubé Syndrome
Molecular Pathogenesis of Renal Neoplasms in Patients with Birt–Hogg–Dubé Syndrome Open
Birt–Hogg–Dubé syndrome (BHDS) is an autosomal dominant disease characterized by skin, lung, and renal manifestations. This syndrome is caused by a germline mutation in the FLCN gene, which leads to disruption in multiple downstream pathwa…
View article: [A deep learning model based on magnetic resonance imaging and clinical feature fusion for predicting preoperative cytokeratin 19 status in hepatocellular carcinoma].
[A deep learning model based on magnetic resonance imaging and clinical feature fusion for predicting preoperative cytokeratin 19 status in hepatocellular carcinoma]. Open
The multi-scale and multi-modality feature fusion model based on MRI and clinical parameters is capable of predicting CK19 status of HCC, demonstrating the feasibility of combining deep learning methods with MRI and clinical features for p…
View article: Seasonal changes of plankton community and its influencing factors in subtropical coastal marine areas revealed by eDNA-based network analysis
Seasonal changes of plankton community and its influencing factors in subtropical coastal marine areas revealed by eDNA-based network analysis Open
Introduction Coastal marine ecosystems are among the most ecologically and socio-economically dynamic regions on Earth, and the study of eukaryotic planktonic communities is an important aspect of aquatic ecology. It is essential to monito…
View article: A Novel Compound Heterozygous Mutation in TDRD9 Causes Oligozoospermia
A Novel Compound Heterozygous Mutation in TDRD9 Causes Oligozoospermia Open
View article: Correction: STING-dependent trained immunity contributes to host defense against Clostridium perfringens infection via mTOR signaling
Correction: STING-dependent trained immunity contributes to host defense against Clostridium perfringens infection via mTOR signaling Open
View article: Sensitivity Analysis of Different Factors in the New Pipe Curtain Freezing Method under Seepage Conditions
Sensitivity Analysis of Different Factors in the New Pipe Curtain Freezing Method under Seepage Conditions Open
This paper takes the freezing project of the North Arch Tunnel of the Hong Kong–Zhuhai–Macao Bridge as an example. Based on Darcy’s law and the theory of heat transfer in porous media, using the coupled module of the temperature field and …
View article: Characteristic morphology and immunohistochemical patterns of clear cell papillary renal cell tumours may be observed in renal cell carcinomas, a critical pitfall in renal biopsy cytopathology
Characteristic morphology and immunohistochemical patterns of clear cell papillary renal cell tumours may be observed in renal cell carcinomas, a critical pitfall in renal biopsy cytopathology Open
Background Clear cell papillary renal cell tumour (CCPRCT) was renamed from previous clear cell papillary renal cell carcinoma (CCPRCC) in the latest WHO Classification of Tumours. It is essential to differentiate RCC from CCPRCT in renal …
View article: STING-dependent trained immunity contributes to host defense against Clostridium perfringens infection via mTOR signaling
STING-dependent trained immunity contributes to host defense against Clostridium perfringens infection via mTOR signaling Open
View article: Characterization of a G2M checkpoint-related gene model and subtypes associated with immunotherapy response for clear cell renal cell carcinoma
Characterization of a G2M checkpoint-related gene model and subtypes associated with immunotherapy response for clear cell renal cell carcinoma Open
Clear cell renal cell carcinoma (ccRCC) presents challenges in early diagnosis and effective treatment. In this study, we aimed to establish a prognostic model based on G2M checkpoint-related genes and identify associated clusters in ccRCC…
View article: Novel 3D morphological characteristics for congenital biliary dilatation diagnosis: a case–control study
Novel 3D morphological characteristics for congenital biliary dilatation diagnosis: a case–control study Open
Background: Congenital biliary dilatation (CBD) necessitates the timely removal of dilated bile ducts. Accurate differentiation between CBD and secondary biliary dilatation (SBD) is crucial for treatment decisions, and identification of CB…
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View article: Trained immunity in recurrent Staphylococcus aureus infection promotes bacterial persistence
Trained immunity in recurrent Staphylococcus aureus infection promotes bacterial persistence Open
Bacterial persister cells, a sub-population of dormant phenotypic variants highly tolerant to antibiotics, present a significant challenge for infection control. Investigating the mechanisms of antibiotic persistence is crucial for develop…
View article: CD317+ MSCs expanded with chemically defined media have enhanced immunological anti-inflammatory activities
CD317+ MSCs expanded with chemically defined media have enhanced immunological anti-inflammatory activities Open
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View article: Diagnostic Challenge in Renal Transplantation: Splenosis vs. Post-Transplant Lymphoproliferative Disorder—A Case Report
Diagnostic Challenge in Renal Transplantation: Splenosis vs. Post-Transplant Lymphoproliferative Disorder—A Case Report Open
Splenosis is a benign, acquired condition characterized by the auto-implantation of focal deposits of splenic tissue throughout the peritoneal cavity, most commonly occurring after splenic injury and/or splenectomy. Post-Transplant Lymphop…
View article: Pancreaticobiliary Cytology Practice in 2021: Results of a College of American Pathologists Survey
Pancreaticobiliary Cytology Practice in 2021: Results of a College of American Pathologists Survey Open
Context.— The College of American Pathologists (CAP) surveys provide national benchmarks of pathology practice. Objective.— To investigate pancreaticobiliary cytology practice in domestic and international laboratories in 2021. Design.— We…
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View article: The Implementation of Nongynecologic Reporting Systems in Cytopathology Laboratories Is Highly Variable: Analysis of Data From a 2020 Supplemental Survey of Participants in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology
The Implementation of Nongynecologic Reporting Systems in Cytopathology Laboratories Is Highly Variable: Analysis of Data From a 2020 Supplemental Survey of Participants in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology Open
Context In recent years, several reporting systems have been developed by national and international cytopathology organizations to standardize the evaluation of specific cytopathology specimen types. Objective To assess the current implem…
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View article: The Paris System for Reporting Urinary Cytology: An Updated Review
The Paris System for Reporting Urinary Cytology: An Updated Review Open
The Paris System for Reporting Urinary Cytology (TPS 1.0, published in 2016) is the first standardized, evidence-based reporting system established as an international reporting system for urine specimens after the International Congress o…
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