Xudong Li
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View article: Decoding the Prognosis-Related S100A9high Monocyte in Glioblastoma Using Single-Cell and Spatial Transcriptome Sequencing
Decoding the Prognosis-Related S100A9high Monocyte in Glioblastoma Using Single-Cell and Spatial Transcriptome Sequencing Open
In summary, our results deciphered the heterogeneity of monocytes in glioblastoma and identified a novel poor prognosis-associated monocyte subset, S100A9high monocytes, which foster an immunosuppressive, pro-tumorigenic microen…
View article: 177Lu-Dotatate versus high-dose long-acting octreotide for the treatment of patients with advanced, grade 1-2, well-differentiated gastroenteropancreatic neuroendocrine tumours (XT-XTR008-3-01): an open-label, randomised, phase III trial
177Lu-Dotatate versus high-dose long-acting octreotide for the treatment of patients with advanced, grade 1-2, well-differentiated gastroenteropancreatic neuroendocrine tumours (XT-XTR008-3-01): an open-label, randomised, phase III trial Open
View article: An efficient algorithm for kernel quantile regression
An efficient algorithm for kernel quantile regression Open
Kernel Quantile Regression (KQR) extends classical quantile regression to nonlinear settings using kernel methods, offering powerful tools for modeling conditional distributions. However, its application to large-scale datasets is severely…
View article: A MOF-Mediated Strategy for In Situ Niobium Doping and Synthesis of High-Performance Single-Crystal Ni-Rich Cathodes
A MOF-Mediated Strategy for In Situ Niobium Doping and Synthesis of High-Performance Single-Crystal Ni-Rich Cathodes Open
The development of single-crystal Ni-rich layered cathode materials (SC-NCMs) is regarded as an effective strategy to address the mechanical failure issues commonly associated with polycrystalline counterparts. However, the industrial prod…
View article: <em>Tremella fuciformis</em> polysaccharide suppresses breast cancer by improving hyperinsulinemia via SIRT3 in postmenopausal obese mice
<em>Tremella fuciformis</em> polysaccharide suppresses breast cancer by improving hyperinsulinemia via SIRT3 in postmenopausal obese mice Open
View article: Radiographic Assessment of Successful Lumbar Spinal Fusion: A Systematic Review of Fusion Criteria in Randomized Trials
Radiographic Assessment of Successful Lumbar Spinal Fusion: A Systematic Review of Fusion Criteria in Randomized Trials Open
Study Type Systematic Scoping Review. Introduction Radiographic assessment is crucial for diagnosing symptomatic pseudarthrosis and evaluating spinal fusion outcomes, yet no consensus exists on defining successful lumbar fusion. This scopi…
View article: Breaking Redox Barriers in Lithium-Oxygen Batteries via Multiscale Architecture of Pyridinic Nitrogen-Doped Carbon-Encapsulated Cobalt Catalysts
Breaking Redox Barriers in Lithium-Oxygen Batteries via Multiscale Architecture of Pyridinic Nitrogen-Doped Carbon-Encapsulated Cobalt Catalysts Open
Lithium-oxygen batteries (LOBs) are limited by sluggish oxygen redox kinetics and cathode instability. Herein, we report a cobalt particle catalyst encapsulated in nitrogen-doped carbon (Co@NC) with a three-dimensional hierarchical archite…
View article: Functional Changes of Rhizosphere and Non-Rhizosphere Soils Under the Decline of Pinus sylvestris var. mongolica Plantations
Functional Changes of Rhizosphere and Non-Rhizosphere Soils Under the Decline of Pinus sylvestris var. mongolica Plantations Open
The decline of Mongolian Scots pine (Pinus sylvestris var. mongolica) plantations in the “Three-North” shelterbelt region is closely linked to soil degradation. This study compared rhizosphere and non-rhizosphere soils across different sta…
View article: Interfacial Electron Transfer in Strategically Engineered Pt3Rh/C Ultrafine Alloy Nanoparticle Catalysts Facilitates Exceptional Performance in Li-O2 Batteries
Interfacial Electron Transfer in Strategically Engineered Pt3Rh/C Ultrafine Alloy Nanoparticle Catalysts Facilitates Exceptional Performance in Li-O2 Batteries Open
A major challenge for Li-O2 batteries is the slow kinetics of oxygen reduction (ORR) and evolution (OER) reactions. This work presents a high-performance Pt3Rh/C composite cathode where Pt-Rh nanoalloys are uniformly dispersed on 3D nanopo…
View article: Liquefaction-induced ground failure and structural damage following the March 28, 2025 M 7.9 Myanmar earthquake
Liquefaction-induced ground failure and structural damage following the March 28, 2025 M 7.9 Myanmar earthquake Open
View article: Multi-ion channel functional gel electrolytes enable 1.55 V open-circuit voltage and high conversion efficiency in photorechargeable zinc–air batteries
Multi-ion channel functional gel electrolytes enable 1.55 V open-circuit voltage and high conversion efficiency in photorechargeable zinc–air batteries Open
View article: Diversity and Functional Differences in Soil Bacterial Communities in Wind–Water Erosion Crisscross Region Driven by Microbial Agents
Diversity and Functional Differences in Soil Bacterial Communities in Wind–Water Erosion Crisscross Region Driven by Microbial Agents Open
Soil erosion-prone areas require effective microbial treatments to improve soil bacterial communities and functional traits. Understanding the driving effects of different microbial interventions on soil ecology is essential for restoratio…
View article: Robotic-assisted versus free-hand techniques in adult spinal deformity surgery: a comparative analysis of postoperative outcomes
Robotic-assisted versus free-hand techniques in adult spinal deformity surgery: a comparative analysis of postoperative outcomes Open
Adult spinal deformity (ASD) represents a challenging area in spinal surgery due to its complexity and potential for postoperative complications. While robotic systems have promised enhanced precision for pedicle screw placement, improved …
View article: Decoding the immune microenvironment of secondary chronic myelomonocytic leukemia due to diffuse large B-cell lymphoma with CD19 CAR-T failure by single-cell RNA-sequencing
Decoding the immune microenvironment of secondary chronic myelomonocytic leukemia due to diffuse large B-cell lymphoma with CD19 CAR-T failure by single-cell RNA-sequencing Open
Background: Several studies have demonstrated the occurrence of secondary tumors as a rare but significant complication of chimeric antigen receptor T (CAR-T) cell therapy, underscoring the need for a detailed investigation. Given the limi…
View article: Performance comparison between acrylic and cement-based repair mortars
Performance comparison between acrylic and cement-based repair mortars Open
To evaluate the performance differences between organic and inorganic repair mortar, two types of acrylic organic repair materials and one cement-based inorganic repair material were selected to prepare mortars, and their compressive stren…
View article: A Novel Method for Water Surface Debris Detection Based on YOLOV8 with Polarization Interference Suppression
A Novel Method for Water Surface Debris Detection Based on YOLOV8 with Polarization Interference Suppression Open
Aquatic floating debris detection is a key technological foundation for ecological monitoring and integrated water environment management. It holds substantial scientific and practical value in applications such as pollution source tracing…
View article: Orchestrated Cu2+-coordinated tetracycline-porphyrin self-assembly remodels tumor microenvironment for photo-enhanced immuno-chemodynamic therapy
Orchestrated Cu2+-coordinated tetracycline-porphyrin self-assembly remodels tumor microenvironment for photo-enhanced immuno-chemodynamic therapy Open
Reactive oxygen species (ROS)-based nanodynamic therapy is emerging as a promising approach for tumor treatment, particularly in eliciting immune responses for tumor immunotherapy. Nevertheless, the complex tumor microenvironment (TME) and…
View article: Targeted next-generation sequencing characterization of respiratory pathogens in children with acute respiratory infection
Targeted next-generation sequencing characterization of respiratory pathogens in children with acute respiratory infection Open
This study represents the first investigation utilizing oropharyngeal swabs for tNGS in diagnosing and treating ARIs. By analyzing surveillance data from a local hospital's patients with ARIs, we have identified the spectrum of bacterial a…
View article: Novel approaches to aqueous zinc-ion batteries: Challenges, strategies, and prospects
Novel approaches to aqueous zinc-ion batteries: Challenges, strategies, and prospects Open
Aqueous zinc-ion batteries (AZIBs) represent a forefront technology for grid-scale energy storage, distinguished by inherent safety, economic viability, and ecological compatibility. Nevertheless, prevailing AZIBs research remains tethered…
View article: Experimental demonstration of dark current mitigation by an over-inserted plug in a normal conducting very-high-frequency gun
Experimental demonstration of dark current mitigation by an over-inserted plug in a normal conducting very-high-frequency gun Open
The room temperature continuous wave (cw) very-high-frequency (VHF) gun is one of the candidates for the electron gun of the high-repetition-rate free-electron lasers (FELs). The VHF gun operates with a cathode gradient of ∼20 MV/m and an…
View article: Unveiling the roles of Zn content on the thermal conductivity of Mg-8Gd-1Er-xZn-1Mn alloys
Unveiling the roles of Zn content on the thermal conductivity of Mg-8Gd-1Er-xZn-1Mn alloys Open
This study investigates the thermal conduction behavior of Mg-8Gd-1Er-xZn-1Mn (x = 4, 6, 8 wt%) alloys with varying Zn content. The results indicate that the as-cast alloys contain only the W-phase, and its volume fraction increases with t…
View article: Comparison of ATG-thymoglobulin with atg-fresenius in patients with hematological malignancies who undergo allogeneic hematopoietic stem cell transplantation: a propensity score-matched analysis
Comparison of ATG-thymoglobulin with atg-fresenius in patients with hematological malignancies who undergo allogeneic hematopoietic stem cell transplantation: a propensity score-matched analysis Open
View article: Sustained slow-release TGF-β3 in a three-dimensional-printed titanium microporous scaffold composite system promotes ligament-to-bone healing
Sustained slow-release TGF-β3 in a three-dimensional-printed titanium microporous scaffold composite system promotes ligament-to-bone healing Open
View article: A Library of Polyphenol‐Amino Acid Condensates for High‐Throughput Continuous Flow Production of Nanomedicines with Ultra‐High Drug Loading
A Library of Polyphenol‐Amino Acid Condensates for High‐Throughput Continuous Flow Production of Nanomedicines with Ultra‐High Drug Loading Open
Synthesizing high drug‐loading nanomedicines remains a formidable challenge, and achieving universally applicable, continuous, large‐scale engineered production of such nanomedicines presents even greater difficulties. This study presents …
View article: SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer
SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer Open
View article: RIS-assisted Physical Layer Security
RIS-assisted Physical Layer Security Open
We propose a reconfigurable intelligent surface (RIS)-assisted wiretap channel, where the RIS is strategically deployed to provide a spatial separation to the transmitter, and orthogonal combiners are employed at the legitimate receiver to…
View article: Construction and characterization of chimeric FcγR T cells for universal T cell therapy
Construction and characterization of chimeric FcγR T cells for universal T cell therapy Open
View article: Role of Photofunctionalization in Orthopedic Customized Implants
Role of Photofunctionalization in Orthopedic Customized Implants Open
Ultraviolet (UV) photofunctionalization is a promising surface activation strategy for orthopedic implants that offers a safe, coating-free, and intraoperatively applicable approach to enhance bone implant integration. This commentary eval…
View article: Enhancing Intermolecular Interactions through Side-Group Halogenation in Dithieno[3,2-b:2',3'-d]benzo[1,2-b:4,5-b']dithiophene Copolymers for Semi-Transparent Organic Solar Cells
Enhancing Intermolecular Interactions through Side-Group Halogenation in Dithieno[3,2-b:2',3'-d]benzo[1,2-b:4,5-b']dithiophene Copolymers for Semi-Transparent Organic Solar Cells Open
View article: Design of Mixed-Valent Fe/Mn Bimetallic Mof-Modified Carbon Fiber Paper Cathode for Electro-Fenton Degradation of 2-Mercaptobenzothiazole
Design of Mixed-Valent Fe/Mn Bimetallic Mof-Modified Carbon Fiber Paper Cathode for Electro-Fenton Degradation of 2-Mercaptobenzothiazole Open