Xiaobin Zheng
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View article: A plasma metabolite-based test to detect minimal residual disease in post-surgery patients with colorectal cancer
A plasma metabolite-based test to detect minimal residual disease in post-surgery patients with colorectal cancer Open
Colorectal cancer (CRC) is among the leading causes of cancer-related deaths worldwide, predominantly caused by recurrence, underscoring the need for novel biomarkers for the early detection of relapse. We hypothesize that patients' respon…
View article: Chinese Expert Consensus on Leptomeningeal Metastases of Lung Cancer
Chinese Expert Consensus on Leptomeningeal Metastases of Lung Cancer Open
Lung cancer patients with leptomeningeal metastases (LMs) suffer from severe clinical symptoms, poor quality of life, narrow diagnostic and therapeutic time windows, low response to standard treatments, short survival periods, and poor pro…
View article: Self-crosslinked cellulose for tough ionogel
Self-crosslinked cellulose for tough ionogel Open
View article: Expert consensus on cancer treatment-related lung injury
Expert consensus on cancer treatment-related lung injury Open
The consensus provides a detailed diagnostic protocol for CTLI and introduces a structured management framework based on grading, typing, and staging. It highlights the critical role of multidisciplinary team (MDT) collaboration and emphas…
View article: Response to Commentary on ‘Diminished levels of insulin‐like growth factor‐1 may be a risk factor for peripheral neuropathy in type 2 diabetes patients’
Response to Commentary on ‘Diminished levels of insulin‐like growth factor‐1 may be a risk factor for peripheral neuropathy in type 2 diabetes patients’ Open
We truly value the readers' meticulousness and conscientiousness. Future studies will incorporate these instructive recommendations to further investigate diabetic neuropathy.
View article: Transanal vs Laparoscopic Total Mesorectal Excision and 3-Year Disease-Free Survival in Rectal Cancer
Transanal vs Laparoscopic Total Mesorectal Excision and 3-Year Disease-Free Survival in Rectal Cancer Open
Importance Previous studies have demonstrated the advantages of short-term histopathological outcomes and complications associated with transanal total mesorectal excision (TME) compared with laparoscopic TME. However, the long-term oncolo…
View article: Prognostic Value of Surgical Resection for Non-small-cell Lung Cancer Patients Comorbid With Minimal Pleural Effusion
Prognostic Value of Surgical Resection for Non-small-cell Lung Cancer Patients Comorbid With Minimal Pleural Effusion Open
Background The proportion and impact of minimal pleural effusion (PE) on prognosis remain blurred in operable non-small cell lung cancer (NSCLC) patients who reported minimal PE on imaging. Methods Clinical and prognostic data of operable …
View article: Artificial Intelligence-Based Algorithm for Pathological Response Assessment to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: A Multi-Center Derived Platform Can Shrink a Mountainous Task into a Molehill
Artificial Intelligence-Based Algorithm for Pathological Response Assessment to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: A Multi-Center Derived Platform Can Shrink a Mountainous Task into a Molehill Open
View article: Clinical Association of Negative Lymph Nodes With Adjuvant Chemotherapy in Patients With T3N0 Rectal Cancer
Clinical Association of Negative Lymph Nodes With Adjuvant Chemotherapy in Patients With T3N0 Rectal Cancer Open
Background: The use of adjuvant chemotherapy in patients with stage T3N0 rectal cancer following total mesorectal excision (TME) is debated. This study is aimed at investigating the clinical significance of negative lymph node (NLN) counts…
View article: Intracranial Efficacy of Crizotinib and Superior Post-Progression Outcomes with Next-Generation ROS1 Inhibitors in Advanced ROS1-Rearranged NSCLC: A Chinese Multi-Center Real-World Study
Intracranial Efficacy of Crizotinib and Superior Post-Progression Outcomes with Next-Generation ROS1 Inhibitors in Advanced ROS1-Rearranged NSCLC: A Chinese Multi-Center Real-World Study Open
View article: Supplementary Tables from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Tables from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
Materials were used in the research.
View article: Supplementary Fig. 8 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 8 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 exerts an immunomodulatory effect through YTHDF2-CXCL10 axis.
View article: Supplementary Fig. 3-4 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 3-4 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 expression is positively correlated with CD3+ and CD8+ densities in tumor parenchyma and invasive margin in CRC.
View article: Supplementary Fig. 1 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 1 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 is highly expressed in CRC tissues compared to tumor-adjacent tissue regardless of MMR status.
View article: Supplementary Fig. 9 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 9 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
CXCL10 is indispensable for KRT7-mediated improved responsiveness to ICIs.
View article: Supplementary Fig. 5-7 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 5-7 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
YTHDF2 expression is negatively correlated with CD3+ and CD8+ densities in tumor parenchyma and invasive margin in CRC.
View article: Supplementary Fig. 1 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 1 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 is highly expressed in CRC tissues compared to tumor-adjacent tissue regardless of MMR status.
View article: Supplementary Legends from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Legends from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
Detailed descriptions of supplementary figures.
View article: Supplementary Fig. 5-7 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 5-7 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
YTHDF2 expression is negatively correlated with CD3+ and CD8+ densities in tumor parenchyma and invasive margin in CRC.
View article: Supplementary Legends from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Legends from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
Detailed descriptions of supplementary figures.
View article: Supplementary Fig. 3-4 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 3-4 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 expression is positively correlated with CD3+ and CD8+ densities in tumor parenchyma and invasive margin in CRC.
View article: Supplementary Fig. 2 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 2 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 has no effect on proliferation, migration and invasion of CRC cells.
View article: Supplementary Fig. 8 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 8 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 exerts an immunomodulatory effect through YTHDF2-CXCL10 axis.
View article: Supplementary Fig. 9 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 9 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
CXCL10 is indispensable for KRT7-mediated improved responsiveness to ICIs.
View article: Supplementary Fig. 2 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 2 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 has no effect on proliferation, migration and invasion of CRC cells.
View article: Supplementary Tables from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Tables from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
Materials were used in the research.
View article: Diminished levels of insulin‐like growth factor‐1 may be a risk factor for peripheral neuropathy in type 2 diabetes patients
Diminished levels of insulin‐like growth factor‐1 may be a risk factor for peripheral neuropathy in type 2 diabetes patients Open
Aims/Introduction To investigate risk factors for diabetic peripheral neuropathy (DPN) and to explore the connection between insulin‐like growth factor‐1 (IGF‐1) and DPN in individuals with type 2 diabetes. Materials and Methods A total of…
View article: Clinicopathological and molecular characteristics of colorectal adenosquamous carcinoma in an Asian population
Clinicopathological and molecular characteristics of colorectal adenosquamous carcinoma in an Asian population Open
View article: Mutant KRAS-activated circATXN7 fosters tumor immunoescape by sensitizing tumor-specific T cells to activation-induced cell death
Mutant KRAS-activated circATXN7 fosters tumor immunoescape by sensitizing tumor-specific T cells to activation-induced cell death Open
View article: Effects of tumour budding on adjuvant chemotherapy in colorectal cancer
Effects of tumour budding on adjuvant chemotherapy in colorectal cancer Open
Background High tumour budding has been indicated as a risk factor of poor survival in colorectal cancer. This study aimed to investigate the impact of tumour budding grades and the use of adjuvant chemotherapy on prognosis in patients wit…