Xiaochuan Yang
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View article: Study on Surrounding Rock Stability During Solution Mining and Operation of Salt Cavern Gas Storage with Different Height-to-Diameter Ratios and Burial Depths
Study on Surrounding Rock Stability During Solution Mining and Operation of Salt Cavern Gas Storage with Different Height-to-Diameter Ratios and Burial Depths Open
Salt cavern gas storage (SCGS) is a key development direction for future energy storage. However, the stability of the surrounding rock in underground SCGS remains a challenging issue to be resolved. This study uses numerical simulation me…
View article: Dual–magnetically driven nanozymes for glioblastoma immunotherapy via magnetothermal and NIR–amplified ferroptosis and apoptosis
Dual–magnetically driven nanozymes for glioblastoma immunotherapy via magnetothermal and NIR–amplified ferroptosis and apoptosis Open
View article: AlloStim<sup>®</sup> Immunotherapy Demonstrates Strong Survival Signal in Third-Line Microsatellite Stable Metastatic Colorectal Cancer: Results of a Phase 2B Clinical Trial
AlloStim<sup>®</sup> Immunotherapy Demonstrates Strong Survival Signal in Third-Line Microsatellite Stable Metastatic Colorectal Cancer: Results of a Phase 2B Clinical Trial Open
Third-line metastatic colorectal cancer (CRC) is refractory to chemotherapy and the available third-line therapies have limited efficacy with significant toxicities. Approximately 95% of metastatic CRC patients present with microsatellite …
View article: High specific capacity lithium-ion batteries based on ZnO/MnO hybrid porous carbon nanofiber anode
High specific capacity lithium-ion batteries based on ZnO/MnO hybrid porous carbon nanofiber anode Open
View article: Allo-Priming Reverses Immunosenescence and May Restore Broad Respiratory Viral Protection and Vaccine Responsiveness to the Elderly: Results of a Phase I/II Clinical Trial
Allo-Priming Reverses Immunosenescence and May Restore Broad Respiratory Viral Protection and Vaccine Responsiveness to the Elderly: Results of a Phase I/II Clinical Trial Open
Respiratory viral infections pose a significant health problem that disproportionately affects the elderly. With the aging worldwide population being less responsive to protective vaccines, there is an urgent need for strategies that can p…
View article: Allo-Priming Reverses Immunosenescence and May Restore Broad Respiratory Viral Protection and Vaccine Responsiveness to the Elderly: Results of a Phase I/II Clinical Trial
Allo-Priming Reverses Immunosenescence and May Restore Broad Respiratory Viral Protection and Vaccine Responsiveness to the Elderly: Results of a Phase I/II Clinical Trial Open
Respiratory viral infections pose a significant health problem that disproportionately affects the elderly. With the aging worldwide population being less responsive to protective vaccines, there is an urgent need for strategies that can p…
View article: Dual-Magnetically Driven Nanozymes for Glioblastoma Immunotherapy Via Magnetothermal and Nir-Amplified Ferroptosis and Apoptosis
Dual-Magnetically Driven Nanozymes for Glioblastoma Immunotherapy Via Magnetothermal and Nir-Amplified Ferroptosis and Apoptosis Open
View article: Clinical Translation of an Immunotherapy for MSS/pMMR Metastatic Colorectal Cancer: Results of a Phase 2B Clinical Trial
Clinical Translation of an Immunotherapy for MSS/pMMR Metastatic Colorectal Cancer: Results of a Phase 2B Clinical Trial Open
View article: Abstract No. 116 Ethanol Embolization of Refractory Head and Neck Arteriovenous Malformations with Onyx Treatment History
Abstract No. 116 Ethanol Embolization of Refractory Head and Neck Arteriovenous Malformations with Onyx Treatment History Open
View article: Determining depth of field for slanted lenticular 3D displays
Determining depth of field for slanted lenticular 3D displays Open
The availability of higher resolution display panels has increasingly made glasses-free 3D displays become a viable mainstream commercial product; it is therefore important to define and measure their parameters. We will discuss the measur…
View article: Preparation of hydroxyapatite coated porous carbon nanofibres for DEX loading and enhancing differentiation of BMSCs
Preparation of hydroxyapatite coated porous carbon nanofibres for DEX loading and enhancing differentiation of BMSCs Open
This study aims to prepare DEX loaded and HA coated carbon porous carbon nanofibers. The released DEX and osteoconductivity of HA are proved to accelerate osteo differentiation of BMSCs.
View article: Design and Synthesis of Boronic Acid-Modified Nucleotides for Fluorescent Sensing and Cell Imaging
Design and Synthesis of Boronic Acid-Modified Nucleotides for Fluorescent Sensing and Cell Imaging Open
With the rapidly increasing interest in the field of glycomics, which is the comprehensive study of the roles carbohydrates play in a living system, urgent need for developing quick and highly selective carbohydrate sensors is growing. The…
View article: Full-Color Quantum Dot Light-Emitting Diodes Based on Microcavities
Full-Color Quantum Dot Light-Emitting Diodes Based on Microcavities Open
Full-color display is a primary challenge for the commercialization of quantum dots (QDs). In this study, we utilize the spectral narrowing phenomenon of microcavities to fabricate the red, green and blue quantum dot light-emitting diodes …
View article: Inotuzumab ozogamicin as chemotherapy-sparing salvage in a 67-year-old man with primary refractory B-cell acute lymphoblastic leukemia with high-risk genomic features
Inotuzumab ozogamicin as chemotherapy-sparing salvage in a 67-year-old man with primary refractory B-cell acute lymphoblastic leukemia with high-risk genomic features Open
Older adults with acute lymphoblastic leukemia (ALL) continue to have a poor prognosis, in part due to greater chemotherapy-related toxicities. We herein report a 67-year-old man with Philadelphia chromosome (Ph)-negative B-cell ALL, who e…
View article: Tumor Growth Assessment by Computed Tomography Perfusion Imaging (CTPI), Perfusion-Weighted Imaging (PWI), and Diffusion-Weighted Imaging (DWI) in a Rabbit Pleural Squamous Cell Carcinoma VX2-Implanted Model
Tumor Growth Assessment by Computed Tomography Perfusion Imaging (CTPI), Perfusion-Weighted Imaging (PWI), and Diffusion-Weighted Imaging (DWI) in a Rabbit Pleural Squamous Cell Carcinoma VX2-Implanted Model Open
BACKGROUND Computed tomography perfusion imaging (CTPI) and perfusion-weighted imaging (PWI) are non-invasive technologies that can quantify tumor vascularity and blood flow. This study explored the blood flow information, tumor cell viabi…
View article: Layer-by-layer nanofiber-enabled engineering of biomimetic periosteum for bone repair and reconstruction
Layer-by-layer nanofiber-enabled engineering of biomimetic periosteum for bone repair and reconstruction Open
View article: Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocarcinogenesis via modulating TGF‑β/TβR and Imp7/8
Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocarcinogenesis via modulating TGF‑β/TβR and Imp7/8 Open
Compound Astragalus and Salvia miltiorrhiza extract (CASE) is a Chinese herbal formula consisting of astragalosides, astragalus polysaccharide and salvianolic acids extracted from Astragalus membranaceus and Salvia …
View article: Formation of organic molecular nanocrystals under soft confinement
Formation of organic molecular nanocrystals under soft confinement Open
Methods to produce nano-sized organic molecular crystals in thin films are of great interest in the pharmaceutical industry due to the potential benefit of increased solubility of poorly soluble drugs and the advantages of film-based dosag…
View article: Design, Synthesis, and Structure−Activity Relationship, Molecular Modeling, and NMR Studies of a Series of Phenyl Alkyl Ketones as Highly Potent and Selective Phosphodiesterase-4 Inhibitors
Design, Synthesis, and Structure−Activity Relationship, Molecular Modeling, and NMR Studies of a Series of Phenyl Alkyl Ketones as Highly Potent and Selective Phosphodiesterase-4 Inhibitors Open
Phosphodiesterase 4 catalyzes the hydrolysis of cyclic AMP and is a target for the development of anti-inflammatory agents. We have designed and synthesized a series of phenyl alkyl ketones as PDE4 inhibitors. Among them, 13 compounds were…
View article: The Effects of Femtosecond Laser Processing on the Surface Accuracy of Fibre Laser Clad Sidewalls
The Effects of Femtosecond Laser Processing on the Surface Accuracy of Fibre Laser Clad Sidewalls Open
\n\tTo enhance the surface accuracy of laser metal direct forming pieces, a method applying femtosecond laser to fabricate the cladding sidewalls is proposed in this paper. The effects of laser fluence, scanning speed and scanning strategy…
View article: Thermoacoustic Instability in a Rijke Tube with a Distributed Heat Source
Thermoacoustic Instability in a Rijke Tube with a Distributed Heat Source Open
A Rijke tube with a distributed heat source is investigated. Driven by the widely existing thermoacoustic instability in lean premixed gas turbine combustors, this work aims to explore the physicochemical underpinning and assist in the elu…
View article: Rapid creation of skin substitutes from human skin cells and biomimetic nanofibers for acute full-thickness wound repair
Rapid creation of skin substitutes from human skin cells and biomimetic nanofibers for acute full-thickness wound repair Open
View article: Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production
Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production Open
View article: Spatiotemporal Analyses of Osteogenesis and Angiogenesis via Intravital Imaging in Cranial Bone Defect Repair
Spatiotemporal Analyses of Osteogenesis and Angiogenesis via Intravital Imaging in Cranial Bone Defect Repair Open
Osteogenesis and angiogenesis are two integrated components in bone repair and regeneration. A deeper understanding of osteogenesis and angiogenesis has been hampered by technical difficulties of analyzing bone and neovasculature simultane…
View article: Formation of organic molecular nanocrystals under soft confinement
Formation of organic molecular nanocrystals under soft confinement Open
We report the use of a novel solution impregnation method to form nanocrystals in polymer matrices with various microstructures in order to study the structure of the confined nanocrystals and the role of soft confinement and polymer chemi…