Xiaohan Tian
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View article: Efferocytosis: the art of cellular clearance and novel perspectives in disease therapy
Efferocytosis: the art of cellular clearance and novel perspectives in disease therapy Open
Efferocytosis, the process of apoptotic cell clearance, is a fundamental biological mechanism for maintaining tissue homeostasis. However, its role in disease pathogenesis is often oversimplified, neglecting a critical knowledge gap: how t…
View article: Physical-Digital and Social-Nonsocial Extracurricular Engagement: Differential Effects on Brain Development and Psychological Outcomes in Children
Physical-Digital and Social-Nonsocial Extracurricular Engagement: Differential Effects on Brain Development and Psychological Outcomes in Children Open
Extracurricular activities shape children’s development, yet how the interaction between their modality (digital/physical) and social context (social/non-social) impact mental health and neurodevelopment remains unclear. This study examine…
View article: Lead (Pb) load interacts with oxidative stress in Drosophila melanogaster through MTF-1/Nrf2/JNK mediated metallothionein expression
Lead (Pb) load interacts with oxidative stress in Drosophila melanogaster through MTF-1/Nrf2/JNK mediated metallothionein expression Open
Lead (Pb) is one of the most severe and hazardous forms of heavy metal pollution, exerting its cytotoxicity primarily by inducing oxidative stress. The existing research focused on the effects of Pb on the redox balance of various organism…
View article: TransBrain: A computational framework for translating brain-wide phenotypes between humans and mice
TransBrain: A computational framework for translating brain-wide phenotypes between humans and mice Open
Despite remarkable advances in whole-brain imaging technologies, the lack of quantitative approaches to bridge rodent preclinical and human studies remains a critical challenge. Here we present TransBrain, a computational framework enablin…
View article: Identification of SikCDPK family genes to low-temperature by RNA-seq approaches and functional analysis of SikCDPK1 in Saussurea involucrata (Kar. & Kir.)
Identification of SikCDPK family genes to low-temperature by RNA-seq approaches and functional analysis of SikCDPK1 in Saussurea involucrata (Kar. & Kir.) Open
Calcium-Dependent Protein Kinases (CDPKs) are a class of serine/threonine protein kinases encoded by several gene families that play key roles in biotic and abiotic stresses response and plant growth and development. However, snow lotus ( …
View article: Longevity or Well-being? A Dual-Dimension Structure of Neuroticism
Longevity or Well-being? A Dual-Dimension Structure of Neuroticism Open
The development of personality traits is often viewed as evolutionarily adaptive. Current neuroticism research, however, predominantly highlights its negative health impacts, neglecting its potential evolutionary advantages. We propose tha…
View article: Probing Individual Differences in the Topological Landscape of Naturalistic Brain Dynamics
Probing Individual Differences in the Topological Landscape of Naturalistic Brain Dynamics Open
Psychiatry seeks to unravel brain dysfunction and individual differences in real-world contexts. Naturalistic stimuli, like movie watching, are increasingly recognized for eliciting complex, context-dependent neural activity with high ecol…
View article: Mapping Brain Synergy Dysfunction in Schizophrenia: Understanding Individual Differences and Underlying Molecular Mechanisms
Mapping Brain Synergy Dysfunction in Schizophrenia: Understanding Individual Differences and Underlying Molecular Mechanisms Open
To elucidate the brain‐wide information interactions that vary and contribute to individual differences in schizophrenia (SCZ), an information‐resolved method is employed to construct individual synergistic and redundant interaction matric…
View article: Association between prolactin/testosterone ratio and breast cancer in Chinese women
Association between prolactin/testosterone ratio and breast cancer in Chinese women Open
To the Editor: Breast cancer is a prevalent malignant tumor and ranks as the second leading cause of cancer-related deaths globally.[1] The breast is the target organ of some endocrine hormones, which regulate its growth and development. A…
View article: Deciphering complex brain spatiotemporal dynamics shaping diverse human behavior
Deciphering complex brain spatiotemporal dynamics shaping diverse human behavior Open
As a complex dynamic system, the brain remains notably active even at rest. Yet, the behavioral significance of such spontaneous activity is largely uncharted. We hypothesize that the variations in human behavior between individuals are em…
View article: Research on the evaluation of the quality of elderly services based on the entropy-rank sum ratio method
Research on the evaluation of the quality of elderly services based on the entropy-rank sum ratio method Open
Objective: To study the differences in the quality of elderly services in various regions of China, and to provide reference for the high-quality development of elderly services in various regions; Method: Combining the existing research r…
View article: Hierarchical Fluctuation Shapes a Dynamic Flow Linked to States of Consciousness
Hierarchical Fluctuation Shapes a Dynamic Flow Linked to States of Consciousness Open
Consciousness emerges from the spatiotemporal dynamics of neural activity. However, how such an extraordinary phenomenon is supported by neural flexibility and regional specialization across the cerebral cortex remains elusive. Here, using…
View article: Introducing Extended DEMO Construction Model to RPA Application
Introducing Extended DEMO Construction Model to RPA Application Open
Business Process technology has long been discussed in various business process methodologies with diverse perspectives.Among them, the discussions on were mainly limited only in effectively fulfilling functional, informational and organiz…