Min Huang
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View article: Early identification of rapid progressive myocardial injury in Duchenne muscular dystrophy: a prospective, single-center cohort study
Early identification of rapid progressive myocardial injury in Duchenne muscular dystrophy: a prospective, single-center cohort study Open
Background Episodes of acute heart failure and sudden death are always reported in Duchenne muscular dystrophy. However, the development process of secretive myocardial injury before malignant events in DMD is not easy to identify in the e…
View article: Organoids in biliary research: insights into developmental signaling and applications in disease modeling
Organoids in biliary research: insights into developmental signaling and applications in disease modeling Open
The embryonic development of the biliary system is orchestrated by complex signaling pathways, including Notch, TGF-β, Wnt, and GFs, which regulate biliary stem/progenitor cell fate, polarity, and ductal morphogenesis. These pathways not o…
View article: The toxicity of guaiacol on craniofacial cartilage development through ROS-induced oxidative stress in zebrafish embryos
The toxicity of guaiacol on craniofacial cartilage development through ROS-induced oxidative stress in zebrafish embryos Open
The combustion of biomass (e.g., wood, agricultural residues) and coal releases significant amounts of guaiacol (GUA) and its derivatives, major constituents of PM2.5 that threaten human health and ecosystems. GUA can rapidly enter the Ear…
View article: Single- and multiple-locus model genome-wide association study for growth traits in Dongliao black pigs
Single- and multiple-locus model genome-wide association study for growth traits in Dongliao black pigs Open
Objective: Growth traits are one of the most important economic traits in pigs, including body weight and average daily gain. However, the available genetic markers for these traits are limited, especially concerning Chinese indigenous pig…
View article: Comparison of fecal microbiota and metabolites in diarrheal piglets pre-and post-weaning
Comparison of fecal microbiota and metabolites in diarrheal piglets pre-and post-weaning Open
Introduction Diarrhea after weaning of piglets is one of the most serious diseases in pig herds, which brings huge economic losses to the pig industry. Diarrhea in piglets after weaning has a significant impact on the composition of gut mi…
View article: A telomere‐to‐telomere gap‐free assembly integrating multi‐omics uncovers the genetic mechanism of fruit quality and important agronomic trait associations in pomegranate
A telomere‐to‐telomere gap‐free assembly integrating multi‐omics uncovers the genetic mechanism of fruit quality and important agronomic trait associations in pomegranate Open
Summary Pomegranate is an important perennial fruit tree distributed worldwide. Reference genomes with gaps and limit gene identification controlling important agronomic traits hinder its functional genomics and genetic improvements. Here,…
View article: Genome-Wide Association Studies of Body Weight and Average Daily Gain in Chinese Dongliao Black Pigs
Genome-Wide Association Studies of Body Weight and Average Daily Gain in Chinese Dongliao Black Pigs Open
In the domain of swine production, body weight (BW) and average daily gain (ADG) are recognized as the primary performance indicators. Nevertheless, the genetic architecture of ADG and BW in Dongliao black (DLB) pigs remains to be fully el…
View article: Origins, Dispersal, and Impact: Bidirectional Introgression Between Chinese and European Pig Populations
Origins, Dispersal, and Impact: Bidirectional Introgression Between Chinese and European Pig Populations Open
Human mediated intra‐continental exchange of genetic material among domesticated organisms has never been restricted to a single direction. The introduction of pig breeds between China and Europe aims to enhance economically important trai…
View article: Soluble Factors and Mechanisms Regulated by Sialylated <scp>IgG</scp> Signaling
Soluble Factors and Mechanisms Regulated by Sialylated <span>IgG</span> Signaling Open
Inflammation is a complex biological response that can be both induced and actively suppressed by IgG‐Fc gamma receptor (FcγR) interactions. This review explores the role of IgG sialylation in reducing or blocking inflammatory responses. W…
View article: The Impact of Mutant EDNRB on the Two-End Black Coat Color Phenotype in Chinese Local Pigs
The Impact of Mutant EDNRB on the Two-End Black Coat Color Phenotype in Chinese Local Pigs Open
Endothelin Receptor Type B (EDNRB) is expressed in a variety of cells during embryonic stage, including melanocyte precursors cells. Our previous studies found that 11 bp deletion of EDNRB caused the two-end black (TEB) coat color in Chine…
View article: Yunpiqiangshen gel improves quality of life in dialysis patients.
Yunpiqiangshen gel improves quality of life in dialysis patients. Open
Compared with the standards of care, added Yunpiqiangshen gel was a safe and effective therapy for improving QOL in dialysis patients.
View article: Height development and multiple bone health indicators in children aged 2–12 years with Duchenne muscular dystrophy (DMD)
Height development and multiple bone health indicators in children aged 2–12 years with Duchenne muscular dystrophy (DMD) Open
Introduction Short stature is a frequent complication of DMD, and its pathomechanisms and influencing factors are specific to this disease and the idiosyncratic treatment for DMD. Purpose To establish the height growth curve of early DMD, …
View article: Demazure product and hopping in type D
Demazure product and hopping in type D Open
The Demazure product, also called the 0-Hecke product, is an associative operation on Coxeter groups with interesting properties and applications. In (Li et al 2024) it was shown that the Demazure product of two permutations can be describ…
View article: Deciphering the Genetic Landscape: Insights Into the Genomic Signatures of Changle Goose
Deciphering the Genetic Landscape: Insights Into the Genomic Signatures of Changle Goose Open
The Changle goose (CLG), a Chinese indigenous breed, is celebrated for its adaptability, rapid growth, and premium meat quality. Despite its agricultural value, the exploration of its genomic attributes has been scant. Our study entailed w…
View article: Physiologically-based pharmacokinetic modelling to investigate the effect of CYP3A4/3A5 maturation on tacrolimus pharmacokinetics in paediatric HSCT patients
Physiologically-based pharmacokinetic modelling to investigate the effect of CYP3A4/3A5 maturation on tacrolimus pharmacokinetics in paediatric HSCT patients Open
Tacrolimus (FK506) is a cornerstone of GVHD-prophylaxis treatment in paediatrics undergoing haematopoietic stem cell transplantation (HSCT). However, due to concerns about highly inter/intra-individual variability, precision dosing of FK50…
View article: Exposure of pregnant women to neonicotinoids in Wenzhou City, East China: A biomonitoring study
Exposure of pregnant women to neonicotinoids in Wenzhou City, East China: A biomonitoring study Open
Overall, pregnant women in Wenzhou City showed a notable frequency of exposure to at least one neonicotinoid, although the exposure frequency for each specific neonicotinoid was generally low. Several food items derived from plants and ani…
View article: A high-quality assembly reveals genomic characteristics, phylogenetic status and causal genes for white feather of Indian peafowl
A high-quality assembly reveals genomic characteristics, phylogenetic status and causal genes for white feather of Indian peafowl Open
Indian peafowl (Pavo cristatus) attracts people’s attention because of the exclusively dazzling phenotypic characteristics. However, little is known about the phenotypic evolution and phylogeny of Indian peafowl at the whole-genome level. …
View article: WITHDRAWN: Genomic and Phenotypic Consequences of Bi-Directional Introgression Between Chinese and European Pig Breeds
WITHDRAWN: Genomic and Phenotypic Consequences of Bi-Directional Introgression Between Chinese and European Pig Breeds Open
Withdrawal Statement The authors have withdrawn this manuscript because [the results have been updated with new data and revised analyses]. Therefore, the authors do not wish this work to be cited as reference for the project. If you have …
View article: Genomic selection analysis of morphological and adaptation traits in Chinese indigenous dog breeds
Genomic selection analysis of morphological and adaptation traits in Chinese indigenous dog breeds Open
The significant morphological differences and abundant germplasm resources of Chinese indigenous dog breeds can be attributed to the diverse geographical environment, including plateaus, mountains, and a long history of raising dogs. The c…
View article: Plant Protection against Viruses: An Integrated Review of Plant Immunity Agents
Plant Protection against Viruses: An Integrated Review of Plant Immunity Agents Open
Plant viruses are an important class of pathogens that seriously affect plant growth and harm crop production. Viruses are simple in structure but complex in mutation and have thus always posed a continuous threat to agricultural developme…
View article: Integrated transcriptome reveals that d-limonene inhibits Candida tropicalis by disrupting metabolism
Integrated transcriptome reveals that d-limonene inhibits Candida tropicalis by disrupting metabolism Open
d-limonene is a common natural flavor additive in food industry. Meanwhile, it can also inhibit the opportunistic pathogens Candida tropicalis by disrupting the relative balance of cell phenotypic parameters, but the molecular mechanism is…
View article: Signal Suppression in LC-ESI-MS/MS from Concomitant Medications and Its Impact on Quantitative Studies: An Example Using Metformin and Glyburide
Signal Suppression in LC-ESI-MS/MS from Concomitant Medications and Its Impact on Quantitative Studies: An Example Using Metformin and Glyburide Open
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been widely used in the quantitative analysis of drugs. The ubiquitous concomitant drug scenario in the clinic has spawned a large number of co-analyses based on this technique.…
View article: Supplementary Material for: Analysis of Dopamine receptor D2 Gene Polymorphism and Correlation with Dyslipidemia in the Chinese population
Supplementary Material for: Analysis of Dopamine receptor D2 Gene Polymorphism and Correlation with Dyslipidemia in the Chinese population Open
Objective: The study aimed to explore the genotype and allele distributions of dopamine D2-like receptor (DRD2) gene -141C and C957T polymorphisms in the Chinese Han population with dyslipidemia, as well as their association with serum lip…
View article: Chromosome-level genome and population genomics reveal evolutionary characteristics and conservation status of Chinese indigenous geese
Chromosome-level genome and population genomics reveal evolutionary characteristics and conservation status of Chinese indigenous geese Open
Geese are herbivorous birds that play an essential role in the agricultural economy. We construct the chromosome-level genome of a Chinese indigenous goose (the Xingguo gray goose, XGG; Anser cygnoides ) and analyze the adaptation of fat s…
View article: Settling effect of abutment and torque loss in different types of abutment after cyclic loading.
Settling effect of abutment and torque loss in different types of abutment after cyclic loading. Open
The screw removal torque was significantly reduced for all groups in this study after cyclic loading. Differences could be found in the internal accuracy of implant-abutment assembly among different groups. Within the limitations of this st…