Xiaohuan Chao
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View article: Estradiol Reverses Ovariectomy-Induced Disruption of Hypothalamic Gene Expression and Behavior via Modulation of Gonadotropin Releasing Hormone and Calcium Signaling Pathways
Estradiol Reverses Ovariectomy-Induced Disruption of Hypothalamic Gene Expression and Behavior via Modulation of Gonadotropin Releasing Hormone and Calcium Signaling Pathways Open
Estrogen plays a crucial role in regulating reproductive and neuroendocrine functions, yet the molecular mechanisms underlying its effects on the hypothalamus remain incompletely understood. This study investigates the transcriptional and …
View article: Heat Stress Influences Immunity Through DUSP1 and HSPA5 Mediated Antigen Presentation in Chickens
Heat Stress Influences Immunity Through DUSP1 and HSPA5 Mediated Antigen Presentation in Chickens Open
The objective of this study was to elucidate the immune system response to heat stress in chickens. In this study, mRNA-seq was conducted on the spleen and bursa of experimental chickens, six differentially expressed genes associated with …
View article: Abnormal DNA methylation of EBF1 regulates adipogenesis in chicken
Abnormal DNA methylation of EBF1 regulates adipogenesis in chicken Open
View article: Application of mRNA-Seq and Metagenomic Sequencing to Study Salmonella pullorum Infections in Chickens
Application of mRNA-Seq and Metagenomic Sequencing to Study Salmonella pullorum Infections in Chickens Open
The disease caused by Salmonella pullorum has been demonstrated to exert a deleterious effect on the performance of poultry, giving rise to elevated mortality and considerable economic losses within the breeding industry. However, there is…
View article: Unraveling the molecular basis of aggression in pigs through integrated transcriptomic and metabolomic analyses
Unraveling the molecular basis of aggression in pigs through integrated transcriptomic and metabolomic analyses Open
View article: EGR1 mRNA expression levels and polymorphisms are associated with slaughter performance in chickens
EGR1 mRNA expression levels and polymorphisms are associated with slaughter performance in chickens Open
With the implementation of the policy of "centralized slaughtering and chilled to market" and the development of the livestock processing industry, numerous researchers have begun to focus on the selection and breeding of broilers bred for…
View article: Genome-Wide Analysis Reveals Copy Number Variant Gene TGFBR3 Regulates Pig Back Fat Deposition
Genome-Wide Analysis Reveals Copy Number Variant Gene TGFBR3 Regulates Pig Back Fat Deposition Open
BFT is closely related to meat quality and lean meat percentage in pigs. The BFT traits of European LW pigs significantly differ from those of Chinese indigenous fatty MZ pigs. CNV is a prevalent genetic variation that plays an important r…
View article: Automatic Quality Assessment of Pork Belly via Deep Learning and Ultrasound Imaging
Automatic Quality Assessment of Pork Belly via Deep Learning and Ultrasound Imaging Open
Pork belly, prized for its unique flavor and texture, is often overlooked in breeding programs that prioritize lean meat production. The quality of pork belly is determined by the number and distribution of muscle and fat layers. This stud…
View article: ALKBH5 regulates chicken adipogenesis by mediating LCAT mRNA stability depending on m6A modification
ALKBH5 regulates chicken adipogenesis by mediating LCAT mRNA stability depending on m6A modification Open
View article: Deciphering Estrus Expression in Gilts: The Role of Alternative Polyadenylation and LincRNAs in Reproductive Transcriptomics
Deciphering Estrus Expression in Gilts: The Role of Alternative Polyadenylation and LincRNAs in Reproductive Transcriptomics Open
The fertility rate and litter size of female pigs are critically affected by the expression of estrus. The objective of this study was to elucidate the regulatory mechanisms of estrus expression by analyzing the differential expression of …
View article: Integrated Transcriptomic Analysis of Vulva and Vagina Explores the Regulation of Long Intergenic Non-coding RNAs and Alternative Polyadenylation in Estrus Expression of Gilts
Integrated Transcriptomic Analysis of Vulva and Vagina Explores the Regulation of Long Intergenic Non-coding RNAs and Alternative Polyadenylation in Estrus Expression of Gilts Open
The fertility rate and litter size of female pigs are critically affected by the expression of estrus. The objective of this study was to elucidate the regulatory mechanisms of estrus expression by analyzing the differential expression of …
View article: A Functional Single Nucleotide Polymorphism in the 3′ Untranslated Region of the Porcine JARID2 Gene Is Associated with Aggressive Behavior of Weaned Pigs after Mixing
A Functional Single Nucleotide Polymorphism in the 3′ Untranslated Region of the Porcine JARID2 Gene Is Associated with Aggressive Behavior of Weaned Pigs after Mixing Open
In pig production, pigs often show more aggressive behavior after mixing, which adversely affects animal welfare and growth performance. The Jumonji and structural domain-rich AT interaction domain 2 (JARID2) gene plays an important role i…
View article: A Functional Single Nucleotide Polymorphism in the 3'-UTR of the Porcine JARID2 Gene is Associated with Aggressive Behavior of Weaned Pigs after Mixing
A Functional Single Nucleotide Polymorphism in the 3'-UTR of the Porcine JARID2 Gene is Associated with Aggressive Behavior of Weaned Pigs after Mixing Open
In pig production, pigs often show more aggressive behavior after mixing, which adversely affects animal welfare and growth performance. The Jumonji and structural domain-rich AT interaction domain 2 (JARID2) gene plays an important role i…
View article: Comprehensive Genome and Transcriptome Analysis Identifies SLCO3A1 Associated with Aggressive Behavior in Pigs
Comprehensive Genome and Transcriptome Analysis Identifies SLCO3A1 Associated with Aggressive Behavior in Pigs Open
Copy number variation (CNV) represents a significant reservoir of genetic diversity within the genome and exhibits a strong association with economically valuable traits in livestock. The manifestation of aggressive behavior in pigs has de…
View article: Supplementary file of "Comprehensive genome and transcriptome analysis identifies SLCO3A1 associated with aggressive behavior in pigs"
Supplementary file of "Comprehensive genome and transcriptome analysis identifies SLCO3A1 associated with aggressive behavior in pigs" Open
Supplementary file of "Comprehensive genome and transcriptome analysis identifies SLCO3A1 associated with aggressive behavior in pigs"
View article: Supplementary file of "Comprehensive genome and transcriptome analysis identifies SLCO3A1 associated with aggressive behavior in pigs"
Supplementary file of "Comprehensive genome and transcriptome analysis identifies SLCO3A1 associated with aggressive behavior in pigs" Open
Supplementary file of "Comprehensive genome and transcriptome analysis identifies SLCO3A1 associated with aggressive behavior in pigs"
View article: Figures and table of "Comprehensive genome and transcriptome analysis identifies SLCO3A1 associated with aggressive behavior in pigs"
Figures and table of "Comprehensive genome and transcriptome analysis identifies SLCO3A1 associated with aggressive behavior in pigs" Open
Figures and table of "Comprehensive genome and transcriptome analysis identifies SLCO3A1 associated with aggressive behavior in pigs"
View article: Stevioside Improves Antioxidant Capacity and Intestinal Barrier Function while Attenuating Inflammation and Apoptosis by Regulating the NF-κB/MAPK Pathways in Diquat-Induced Oxidative Stress of IPEC-J2 Cells
Stevioside Improves Antioxidant Capacity and Intestinal Barrier Function while Attenuating Inflammation and Apoptosis by Regulating the NF-κB/MAPK Pathways in Diquat-Induced Oxidative Stress of IPEC-J2 Cells Open
As a natural sweetener, stevioside is extracted from Stevia rebaudiana Bertoni and possesses potent antioxidant activity. However, little information is known about its protective role in maintaining the intestinal epithelial cells health …
View article: Acidifiers Attenuate Diquat-Induced Oxidative Stress and Inflammatory Responses by Regulating NF-κB/MAPK/COX-2 Pathways in IPEC-J2 Cells
Acidifiers Attenuate Diquat-Induced Oxidative Stress and Inflammatory Responses by Regulating NF-κB/MAPK/COX-2 Pathways in IPEC-J2 Cells Open
In this study, we evaluated the protective effects and potential mechanisms of acidifiers on intestinal epithelial cells exposure to oxidative stress (OS). IPEC-J2 cells were first pretreated with 5 × 10−5 acidifiers for 4 h before being e…
View article: Effects of dietary supplement with a Chinese herbal mixture on growth performance, antioxidant capacity, and gut microbiota in weaned pigs
Effects of dietary supplement with a Chinese herbal mixture on growth performance, antioxidant capacity, and gut microbiota in weaned pigs Open
Weaning stress decreases the growth performance of piglets and is one of the main concerns of pig industries. Traditional Chinese herbal medicines have been used to reduce the adverse effects of weaning stress as both nutritional supplemen…
View article: Genome-Wide Detection of Copy Number Variations and Evaluation of Candidate Copy Number Polymorphism Genes Associated With Complex Traits of Pigs
Genome-Wide Detection of Copy Number Variations and Evaluation of Candidate Copy Number Polymorphism Genes Associated With Complex Traits of Pigs Open
Copy number variation (CNV) has been considered to be an important source of genetic variation for important phenotypic traits of livestock. In this study, we performed whole-genome CNV detection on Suhuai (SH) ( n = 23), Chinese Min Zhu (…
View article: Comprehensive Transcriptome Analysis of Follicles from Two Stages of the Estrus Cycle of Two Breeds Reveals the Roles of Long Intergenic Non-Coding RNAs in Gilts
Comprehensive Transcriptome Analysis of Follicles from Two Stages of the Estrus Cycle of Two Breeds Reveals the Roles of Long Intergenic Non-Coding RNAs in Gilts Open
Visible and long-lasting estrus expression of gilts and sows effectively sends a mating signal. To reveal the roles of Long Intergenic Non-coding RNAs (lincRNAs) in estrus expression, RNA-seq was used to investigate the lincRNAs expression…
View article: Whole Transcriptome Analysis Reveals a Potential Regulatory Mechanism of LncRNA-FNIP2/miR-24-3p/FNIP2 Axis in Chicken Adipogenesis
Whole Transcriptome Analysis Reveals a Potential Regulatory Mechanism of LncRNA-FNIP2/miR-24-3p/FNIP2 Axis in Chicken Adipogenesis Open
Lipid biosynthesis is a complex process, which is regulated by multiple factors including lncRNA. However, the role of lncRNA in chicken abdominal fat accumulation is still unclear. In this research, we collected liver tissues from six hig…
View article: miR-429-3p/LPIN1 Axis Promotes Chicken Abdominal Fat Deposition via PPARγ Pathway
miR-429-3p/LPIN1 Axis Promotes Chicken Abdominal Fat Deposition via PPARγ Pathway Open
To explore the regulatory mechanism of abdominal fat deposition in broilers, 100-day-old Sanhuang chickens ( n = 12) were divided into high-fat and low-fat groups, according to the abdominal fat ratio size. Total RNA isolated from the 12 a…