Xiaoyun Wu
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View article: Heterogeneous viromes in the salivary glands, ovaries, and midguts suggested differential viral transmission advantages of six tick genera
Heterogeneous viromes in the salivary glands, ovaries, and midguts suggested differential viral transmission advantages of six tick genera Open
The transmission of tick-borne viruses is associated with the biological functions of tick tissues. This study investigated the viromes in salivary glands, ovaries, and midguts collected from nine tick species of six genera and identified …
View article: Whole transcriptomic analysis revealed the effects of different dietary protein levels on the growth and development of Jersey-yak
Whole transcriptomic analysis revealed the effects of different dietary protein levels on the growth and development of Jersey-yak Open
Background The Jersey-yak, a hybrid offspring of Jersey cattle and yak, exhibits characteristics such as strong adaptability, rapid growth and development, and outstanding production performance. Therefore, it is necessary to find a reason…
View article: Diagnostic and prognostic significance of Super-enhancer-associated genes in Crohn’s disease and immune regulatory roles
Diagnostic and prognostic significance of Super-enhancer-associated genes in Crohn’s disease and immune regulatory roles Open
PAQR5, IFITM3, PSMB8, and IRF1 serve as biomarkers for CD, offering substantial diagnostic and immune regulatory value. These biomarkers differentiate CD into two subtypes, providing insights for personalized therapeutic strategies.
View article: The Metabolic Network of Chilled Yak Meat During Storage Was Constructed Based on Metabolomics Technology
The Metabolic Network of Chilled Yak Meat During Storage Was Constructed Based on Metabolomics Technology Open
Chilled yak meat is becoming more and more popular with the improvement in living standards, and the flavor of chilled meat is closely related to storage time. The effect of storage time on the flavor of chilled yak meat was explored in th…
View article: Genetic Variants in the ATF6 Gene and Their Relationship with Milk-Quality Traits in Yaks
Genetic Variants in the ATF6 Gene and Their Relationship with Milk-Quality Traits in Yaks Open
Yaks (Bos grunniens) are a predominant livestock species on the Tibetan Plateau, known for their adaptability to the cold and dry climate typical of this region. This study investigates the association of two SNPs within the ATF6 gene (Chr…
View article: Identification of the prognostic effect of mitophagy-related genes in acute myeloid leukemia
Identification of the prognostic effect of mitophagy-related genes in acute myeloid leukemia Open
Background Mitophagy has been implicated in the pathogenesis of acute myeloid leukemia (AML), yet its precise molecular mechanisms remain poorly understood. Understanding the roles of mitophagy-related genes (MRGs) may provide new insights…
View article: Bovine lactoferricin exerts antibacterial activity against four Gram-negative pathogenic bacteria by transforming its molecular structure
Bovine lactoferricin exerts antibacterial activity against four Gram-negative pathogenic bacteria by transforming its molecular structure Open
The emergence and development of pathogenic bacterial resistance to antibiotics pose significant challenges to human health. Antimicrobial peptides (AMPs) are considered promising alternatives to conventional antibiotics. Lactoferricin (Lf…
View article: Combined application of CNV-seq and whole-exome sequencing for testing fetal abnormalities:a retrospective analysis
Combined application of CNV-seq and whole-exome sequencing for testing fetal abnormalities:a retrospective analysis Open
Background: Birth defects have complex and diverse causes, which have a profound impact on children, families and society. Genetic factors are an important cause of birth defects. Genetic testing of fetal with abnormal intrauterine develop…
View article: BPS causes abnormal blastocyst development by inhibiting cell proliferation
BPS causes abnormal blastocyst development by inhibiting cell proliferation Open
In recent years, the escalating global utilization of bisphenol S (BPS) has raised growing concerns regarding its potential adverse effects on human health. However, the effects of BPS exposure on mammalian embryonic development and the as…
View article: Design of an Automatic Cut Chrysanthemum Cultivation Device
Design of an Automatic Cut Chrysanthemum Cultivation Device Open
In practice, flexible nets are applied, but their support to chrysanthemum is insecure, unable to make it keep upright. Especially, when chrysanthemum is in full blossom, it is likely to fall, which has severely affected marketability of c…
View article: Identification and Analysis of Circular RNAs in Mammary Gland from Yaks Between Lactation and Dry Period
Identification and Analysis of Circular RNAs in Mammary Gland from Yaks Between Lactation and Dry Period Open
Lactation is a complex physiological process regulated by numerous genes and factors. Circular RNA (circRNA), a non-coding RNA, acts as a molecular sponge that sequesters microRNAs (miRNAs) to regulate target gene expression. Although circ…
View article: Comparative Analysis of miRNA Expression Profiles of Yak Milk-Derived Exosomes at Different Altitudes
Comparative Analysis of miRNA Expression Profiles of Yak Milk-Derived Exosomes at Different Altitudes Open
Yaks are a rare and unique animal species inhabiting the Qinghai–Tibet Plateau; they are renowned for their remarkable ability to thrive in harsh environments. Milk-derived exosomes, tiny vesicles containing various biological molecules, p…
View article: Advancements in the Application of scRNA-Seq in Breast Research: A Review
Advancements in the Application of scRNA-Seq in Breast Research: A Review Open
Single-cell sequencing technology provides apparent advantages in cell population heterogeneity, allowing individuals to better comprehend tissues and organs. Sequencing technology is currently moving beyond the standard transcriptome to t…
View article: Polymorphisms of KCNJ6 Gene and Their Correlation with Immune Indicators in Yaks (Bos grunniens)
Polymorphisms of KCNJ6 Gene and Their Correlation with Immune Indicators in Yaks (Bos grunniens) Open
Yaks are crucial to local herders’ economy and agriculture. However, several diseases pose a significant threat to the health of yaks and cause substantial economic losses for herders. Therefore, studying the immune indicators and breeding…
View article: Study of volatile flavor derived from lipids degeneration in yak milk based on semiquantitative lipidomics
Study of volatile flavor derived from lipids degeneration in yak milk based on semiquantitative lipidomics Open
Milk lipids greatly affect the volatile flavor of milk, and the relationship between lipids and volatile flavor in yak milk was explored in this study. The volatile flavor compounds (VFCs), lipids profile, fatty acids in yak ordinary milk …
View article: Whole Genome Scan Uncovers Candidate Genes Related to Milk Production Traits in Barka Cattle
Whole Genome Scan Uncovers Candidate Genes Related to Milk Production Traits in Barka Cattle Open
In this study, our primary aim was to explore the genomic landscape of Barka cattle, a breed recognized for high milk production in a semi-arid environment, by focusing on genes with known roles in milk production traits. We employed genom…
View article: Serum Metabolomic Analysis of Synchronous Estrus in Yaks Based on UPLC-Q-TOF MS Technology
Serum Metabolomic Analysis of Synchronous Estrus in Yaks Based on UPLC-Q-TOF MS Technology Open
The yak is a unique species of livestock found in the Qinghai-Tibet Plateau and its surrounding areas. Due to factors such as late sexual maturity and a low rate of estrus, its reproductive efficiency is relatively low. The process of estr…
View article: Application of GC-IMS, GC-MS, and LC-MS/MS techniques to a comprehensive systematic study on the flavor characteristics of different muscles in the yak
Application of GC-IMS, GC-MS, and LC-MS/MS techniques to a comprehensive systematic study on the flavor characteristics of different muscles in the yak Open
This study aims to explore the key metabolites and metabolic pathways related to the formation of flavor in yak meat, laying the foundation for in-depth analysis of the composition of yak meat and improving meat quality. This study selecte…
View article: Association between Single Nucleotide Polymorphisms of PRKD1 and KCNQ3 Gene and Milk Quality Traits in Gannan Yak (Bos grunniens)
Association between Single Nucleotide Polymorphisms of PRKD1 and KCNQ3 Gene and Milk Quality Traits in Gannan Yak (Bos grunniens) Open
Protein kinase D1 (PRKD1) functions primarily in normal mammary cells, and the potassium voltage-gated channel subfamily Q member 3 (KCNQ3) gene plays an important role in controlling membrane potential and neuronal excitability, it has be…
View article: Genome-Wide Association Analysis of Cowpea Mild Mottle Virus Resistance in Soybean Germplasms from Northeast China
Genome-Wide Association Analysis of Cowpea Mild Mottle Virus Resistance in Soybean Germplasms from Northeast China Open
Cowpea mild mottle virus (CpMMV) is an important viral pathogen that seriously influences the yield and seed quality of soybeans worldwide. Resistance breeding is one of the most effective, economical, and environmentally safe strategies f…
View article: Identification of circRNA-associated ceRNA networks in the longissimus dorsi of yak under different feeding systems
Identification of circRNA-associated ceRNA networks in the longissimus dorsi of yak under different feeding systems Open
Background Yaks (Bos grunniens), prized for their ability to thrive in high-altitude environments, are indispensable livestock in the plateau region. Modifying their feeding systems holds significant promise for improving their growth and …
View article: The Resistance of Soybean Variety Heinong 84 to Apple Latent Spherical Virus Is Controlled by Two Genetic Loci
The Resistance of Soybean Variety Heinong 84 to Apple Latent Spherical Virus Is Controlled by Two Genetic Loci Open
Apple latent spherical virus (ALSV) is widely used as a virus-induced gene silencing (VIGS) vector for function genome study. However, the application of ALSV to soybeans is limited by the resistance of many varieties. In this study, the g…
View article: The Resistance of Soybean Variety Heinong 84 to Apple Latent Spherical Virus Is Controlled by Two Genetic Loci
The Resistance of Soybean Variety Heinong 84 to Apple Latent Spherical Virus Is Controlled by Two Genetic Loci Open
Apple latent spherical virus (ALSV) is widely used as a virus-induced gene silencing (VIGS) vector for function genome study. However, the application of ALSV in soybean is limited by the resistance of many varieties. In this study, the ge…