Xiaojuan Bi
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View article: Host angiogenic reprogramming by Echinococcus multilocularis protoscoleces protein via PDGFR/PI3K/AKT cascade
Host angiogenic reprogramming by Echinococcus multilocularis protoscoleces protein via PDGFR/PI3K/AKT cascade Open
Background Alveolar echinococcosis (AE) is a globally present zoonotic disease caused by Echinococcus multilocularis ( E. multilocularis ) infection, characterized by the formation of tumor-like growths primarily in the liver, with the pot…
View article: Alterations of Raman Profiles of Cystic Echinococcosis Serum After Treated With <scp>ABZ</scp> by <scp>SERS</scp>
Alterations of Raman Profiles of Cystic Echinococcosis Serum After Treated With <span>ABZ</span> by <span>SERS</span> Open
Cystic echinococcosis (CE) is often treated with albendazole (ABZ). Surface‐enhanced Raman scattering (SERS) has high sensitivity and specificity, as well as low sample consumption, but its ability to identify changes in serum compounds po…
View article: Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying Hens
Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying Hens Open
This experiment aimed to investigate the appropriate level of degossypolized cottonseed protein (DGCP) in the diet of laying hens. A total of 600 49-week-old Lohmann pink laying hens were allocated to five treatments, with six replicates p…
View article: CD155 as a therapeutic target in alveolar echinococcosis: insights from an Echinococcus multilocularis infection mouse model
CD155 as a therapeutic target in alveolar echinococcosis: insights from an Echinococcus multilocularis infection mouse model Open
Introduction Alveolar echinococcosis (AE) is a life-threatening zoonotic parasitic disease caused by the metacestode stage of Echinococcus multilocularis , characterized by granulomatous lesions and liver fibrosis. Immune exhaustion is the…
View article: ADSCs attenuate Liver fibrosis via inducing HSC senescence: validation in dual-etiology models
ADSCs attenuate Liver fibrosis via inducing HSC senescence: validation in dual-etiology models Open
Background Liver fibrosis (LF) results from various causes, which require finding conserved mechanisms to help treat related diseases. Although adipose-derived stem cells (ADSCs) transplantation can alleviate hepatic fibrosis, their mechan…
View article: Effects of energy density of diets and dietary Pediococcus acidilactici supplementation on productive performance, egg quality, and intestinal function in laying hens
Effects of energy density of diets and dietary Pediococcus acidilactici supplementation on productive performance, egg quality, and intestinal function in laying hens Open
View article: Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis
Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis Open
Introduction The Th2 immune response plays a pivotal role in the pathogenesis of schistosomiasis, contributing to the formation of hepatic granulomas and fibrosis. While the glucocorticoid receptor (GR) is a ubiquitously expressed nuclear …
View article: Author Correction: Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis
Author Correction: Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis Open
View article: Enhancing Mesenchymal Stem Cell Functionality Through Nestin Overexpression: A Novel Approach for Treating End-Stage Liver Disease
Enhancing Mesenchymal Stem Cell Functionality Through Nestin Overexpression: A Novel Approach for Treating End-Stage Liver Disease Open
Transplantation of mesenchymal stem cells (MSCs) represents a novel therapeutic strategy for end-stage liver disease. However, the clinical application of MSCs is limited by challenges in their proliferation and procurement. In this study,…
View article: Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis
Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis Open
View article: Inhibition of AMPK activation in <i>Echinococcus granulosus</i> sensu stricto limits the parasite’s glucose metabolism and survival
Inhibition of AMPK activation in <i>Echinococcus granulosus</i> sensu stricto limits the parasite’s glucose metabolism and survival Open
Cystic echinococcosis (CE) is a zoonotic parasitic disease caused by larvae of the Echinococcus granulosus sensu lato (s.l.) cluster. There is an urgent need to develop new drug targets and drug molecules to treat CE. Adenosine monophospha…
View article: Adipose-Derived Mesenchymal Stem Cell Facilitate Hematopoietic Stem Cell Proliferation via the Jagged-1/Notch-1/Hes Signaling Pathway
Adipose-Derived Mesenchymal Stem Cell Facilitate Hematopoietic Stem Cell Proliferation via the Jagged-1/Notch-1/Hes Signaling Pathway Open
Background. Poor graft function (PGF) is a life-threatening complication following hematopoietic stem cell transplantation (HSCT). Current therapies, such as CD34+ cell infusion, have shown limited effectiveness. Conversely, mesenchymal st…
View article: Cytokine-induced apoptosis inhibitor 1: a comprehensive analysis of potential diagnostic, prognosis, and immune biomarkers in invasive breast cancer
Cytokine-induced apoptosis inhibitor 1: a comprehensive analysis of potential diagnostic, prognosis, and immune biomarkers in invasive breast cancer Open
The high expression of CIAPIN1 in IBC is significantly related to the infiltration status of various tumor immune cells and the poor prognosis of IBC patients. According to this current study, CIAPIN1 is a promising diagnosti…
View article: Gelsolin: A comprehensive pan-cancer analysis of potential prognosis, diagnostic, and immune biomarkers
Gelsolin: A comprehensive pan-cancer analysis of potential prognosis, diagnostic, and immune biomarkers Open
Introduction: Gelsolin (GSN), a calcium-regulated actin-binding protein, is out of balance in various cancers. It can mediate cytoskeletal remodeling and regulate epithelial-mesenchymal conversion (EMT), but the studies on GSN function in …
View article: Upregulated TUBG1 expression is correlated with poor prognosis in hepatocellular carcinoma
Upregulated TUBG1 expression is correlated with poor prognosis in hepatocellular carcinoma Open
Background Hepatocellular carcinoma (HCC) development is a complex pathological process. Tubulin gamma 1 (TUBG1) plays an oncogenic role in several human cancers; however, its functional role in HCC tumorigenesis remains unknown. Methods H…
View article: Optimization of the Enzymatic Hydrolysis Process of Acer truncatum Seed Meal by Response Surface Methodology and the Functional Characteristics of the Polypeptide Obtained
Optimization of the Enzymatic Hydrolysis Process of Acer truncatum Seed Meal by Response Surface Methodology and the Functional Characteristics of the Polypeptide Obtained Open
In this paper, Acer truncatum seed meal was hydrolyzed by alkaline protease method. The enzymatic hydrolysis time, enzyme dosage, pH, enzymatic hydrolysis temperature and solid-liquid ratio were investigated, and the yield of enzymatic hyd…
View article: TIGIT as a Novel Prognostic Marker for Immune Infiltration in InvasiveBreast Cancer
TIGIT as a Novel Prognostic Marker for Immune Infiltration in InvasiveBreast Cancer Open
Background: To assess the levels and potential therapeutic and prognostic significance of TIGIT in invasive breast cancer. Methods: The Cancer Genome Atlas database was used to evaluate TIGIT levels in invasive breast cancer and its associ…
View article: TIGIT is a novel prognostic marker and correlate for immune infiltration in invasive breast cancer
TIGIT is a novel prognostic marker and correlate for immune infiltration in invasive breast cancer Open
Background To assess the levels and potential therapeutic and prognostic significance of TIGIT in invasive breast cancer. Methods The Cancer Genome Atlas database was used to evaluate TIGIT levels in invasive breast cancer and its associat…
View article: Transplantation of adipose-derived stem cells ameliorates Echinococcus multilocularis-induced liver fibrosis in mice
Transplantation of adipose-derived stem cells ameliorates Echinococcus multilocularis-induced liver fibrosis in mice Open
Background Alveolar echinococcosis (AE) can cause severe liver fibrosis and could be fatal if left untreated. Currently, there are no effective therapeutic options for AE-induced liver fibrosis. In view of the therapeutic potential of adip…
View article: <i>In vitro</i> efficacy of <i>Capparis spinosa</i> extraction against larvae viability of <i>Echinococcus granulosus</i> sensu stricto
<i>In vitro</i> efficacy of <i>Capparis spinosa</i> extraction against larvae viability of <i>Echinococcus granulosus</i> sensu stricto Open
Cystic echinococcosis (CE) is a chronic zoonotic parasitic disease caused by infection with the larvae of the Echinococcus granulosus sensu lato (s.l.) cluster. Currently, new drugs are urgently required due to the poor therapeutic effect …
View article: EgGLUT1 Is Crucial for the Viability of Echinococcus granulosus sensu stricto Metacestode: A New Therapeutic Target?
EgGLUT1 Is Crucial for the Viability of Echinococcus granulosus sensu stricto Metacestode: A New Therapeutic Target? Open
Cystic echinococcosis (CE) is a zoonotic parasitic disease caused by infection with the larvae of Echinococcus granulosus sensu lato ( s.l. ) cluster. It is urgent to identify novel drug targets and develop new drug candidates against CE. …
View article: An improved experimental method for simultaneously isolating hepatocytes and hepatic stellate cells in mouse liver infected with <i>Echinococcus multilocularis</i>
An improved experimental method for simultaneously isolating hepatocytes and hepatic stellate cells in mouse liver infected with <i>Echinococcus multilocularis</i> Open
Background Alveolar echinococcosis (AE) is a zoonotic disease caused by the larval stage of Echinococcus multilocularis parasitizing in the human liver, causing local pathological changes in the liver and manifesting as hyperplasia, liver …
View article: Corrigendum: Upregulated LINC01667 Expression Is Correlated With Poor Prognosis in Hepatocellular Carcinoma
Corrigendum: Upregulated LINC01667 Expression Is Correlated With Poor Prognosis in Hepatocellular Carcinoma Open
[This corrects the article DOI: 10.3389/fonc.2021.650173.].
View article: Upregulated LINC01667 Expression Is Correlated With Poor Prognosis in Hepatocellular Carcinoma
Upregulated LINC01667 Expression Is Correlated With Poor Prognosis in Hepatocellular Carcinoma Open
The development of hepatocellular carcinoma (HCC) is a complex pathological process. Long intergenic non–protein-coding RNA 1667 (LINC01667, also known as MGC38584) plays an oncogenic role in several human cancers; however, its functional …
View article: EgGLUT1 is crucial for the viability of larvae of<i>Echinococcus granulosus sensus lato</i>by involving its glucose uptake
EgGLUT1 is crucial for the viability of larvae of<i>Echinococcus granulosus sensus lato</i>by involving its glucose uptake Open
Cystic echinococcosis (CE) is a zoonotic parasitic disease caused by infection with the larvae of Echinococcus granulosus sensu lato ( s.l. ) cluster. It is urgent to identify novel drug targets and develop new drug candidates against CE. …
View article: Dual Role of Hepatic Macrophages in the Establishment of the Echinococcus multilocularis Metacestode in Mice
Dual Role of Hepatic Macrophages in the Establishment of the Echinococcus multilocularis Metacestode in Mice Open
Echinococcus multilocularis larvae, predominantly located in the liver, cause a tumor-like parasitic disease, alveolar echinococcosis (AE), that is characterized by increased infiltration of various immune cells, including macrophages, aro…
View article: EgGLUT1 is Crucial for the Viability of <i>Echinococcus granulosus sensu stricto</i> Metacestode: A New Therapeutic Target?
EgGLUT1 is Crucial for the Viability of <i>Echinococcus granulosus sensu stricto</i> Metacestode: A New Therapeutic Target? Open
View article: Serum platelet-derived growth factor-BB levels as a potential biomarker in assessing the metabolic activity of lesions in alveolar echinococcosis patients
Serum platelet-derived growth factor-BB levels as a potential biomarker in assessing the metabolic activity of lesions in alveolar echinococcosis patients Open
Objective Alveolar echinococcosis (AE) is a chronic disease caused by the larval stage of Echinococcus multilocularis. Assessing the metabolic activity of AE lesions is critical to evaluate disease progression and survey treatment options.…
View article: Serum Platelet-derived Growth Factor-BB Levels as a Potential Biomarker in Assessing the Metabolic Activity of Lesions in Alveolar Echinococcosis Patients
Serum Platelet-derived Growth Factor-BB Levels as a Potential Biomarker in Assessing the Metabolic Activity of Lesions in Alveolar Echinococcosis Patients Open
ObjectiveAlveolar echinococcosis (AE) is a chronic disease caused by the larval stage of Echinococcus multilocularis. Assessing the metabolic activity of AE lesions is critical to evaluate disease progression and survey treatment options. …
View article: The local immune response during Echinococcus granulosus growth in a quantitative hepatic experimental model
The local immune response during Echinococcus granulosus growth in a quantitative hepatic experimental model Open