Xiaojun Fu
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View article: Application of enhanced recovery after surgery techniques in gastrointestinal surgery patients
Application of enhanced recovery after surgery techniques in gastrointestinal surgery patients Open
BACKGROUND Gastrointestinal surgery has disadvantages such as long operation time, extended hospitalization time, and slow postoperative recovery. However, the promotion and clinical application of the enhanced recovery after surgery (ERAS…
View article: ECM-based molecular subtypes define prognostic, EMT status, and therapeutic diversity in IDH-mutant gliomas
ECM-based molecular subtypes define prognostic, EMT status, and therapeutic diversity in IDH-mutant gliomas Open
IDH-mutant gliomas show prognostic heterogeneity despite favorable overall outcomes, necessitating refined molecular classification. While the extracellular matrix (ECM) critically regulates tumor progression, immunity, and EMT, its progno…
View article: Molecular landscape, subtypes, and therapeutic vulnerabilities of central nervous system solitary fibrous tumors
Molecular landscape, subtypes, and therapeutic vulnerabilities of central nervous system solitary fibrous tumors Open
Solitary fibrous tumors (SFTs) of the central nervous system (CNS) are rare, aggressive mesenchymal neoplasms with high recurrence and metastasis rates. Here, we perform a comprehensive multi-omics analysis of 189 cases of CNS SFTs integra…
View article: Rs61731397-C in OR2A25 increases the risk of chronic rhinosinusitis in the Chinese population
Rs61731397-C in OR2A25 increases the risk of chronic rhinosinusitis in the Chinese population Open
Our findings demonstrate that the missense variant rs61731397-C in OR2A25 increases the risk of chronic rhinosinusitis in the Chinese population. This variant may contribute to CRS pathogenesis by downregulating OR2A25 expression, potentia…
View article: Constructing an Integrated Model of Water and Salt Movement in Irrigation Districts
Constructing an Integrated Model of Water and Salt Movement in Irrigation Districts Open
Irrigation and drainage regulations significantly shape the water and salt dynamics in arid and semiarid irrigation districts. While many numerical models have been developed to study water and salt movement, few incorporate regulatory con…
View article: The Influence of Wind Speed on Pneumatic Conveying Characteristics of Solid Feed in Horizontal Pipe by Simulation and Experiment
The Influence of Wind Speed on Pneumatic Conveying Characteristics of Solid Feed in Horizontal Pipe by Simulation and Experiment Open
Pneumatic conveying technology is an efficient, energy-saving and environmentally friendly means of solid feed conveying. In the process of pneumatic conveying, wind speed has a decisive influence on conveying characteristics. Here, comput…
View article: Leptomeningeal dissemination in H3 K27M- mutant diffuse midline gliomas: clinical characteristics, risk factors, and prognostic insights
Leptomeningeal dissemination in H3 K27M- mutant diffuse midline gliomas: clinical characteristics, risk factors, and prognostic insights Open
The association between contrast-enhanced lesions and ventricular involvement is an independent predictive factor for LMD in DMG patients. Radiotherapy and preoperative KPS may contribute to improved overall survival in these patients. Che…
View article: Spatially Controlled MicroRNA Imaging in Mitochondria via Enzymatic Activation of Hybridization Chain Reaction
Spatially Controlled MicroRNA Imaging in Mitochondria via Enzymatic Activation of Hybridization Chain Reaction Open
Live‐cell imaging of RNA in specific subcellular compartments is essential for elucidating the rich repertoire of cellular functions, but it has been limited by a lack of simple, precisely controlled methods. Here such an approach is prese…
View article: Dysbiosis promotes recurrence of adenomatous polyps in the distal colorectum
Dysbiosis promotes recurrence of adenomatous polyps in the distal colorectum Open
BACKGROUND Colorectal polyps, which are characterized by a high recurrence rate, represent preneoplastic conditions of the intestine. Due to unclear mechanisms of pathogenesis, first-line therapies for non-hereditary recurrent colorectal p…
View article: Study on calculation method for dynamic load distribution of thread pair of planetary roller screw mechanism
Study on calculation method for dynamic load distribution of thread pair of planetary roller screw mechanism Open
To reveal the dynamic load distribution characteristics of planetary roller screw mechanism under the high-speed operating conditions, based on the spiral surface equation and deformation coordination relationship, a static contact force c…
View article: Studies on meshing clearance of thread pairs of planetary roller screw mechanism in different directions
Studies on meshing clearance of thread pairs of planetary roller screw mechanism in different directions Open
The helix surface model of planetary roller screw mechanism (PRSM) is established by utilizing the parametric equations of space surface according to the structural features of screw, roller and nut. The helix surface model of PRSM is impr…
View article: Single-cell RNA sequencing reveals cellular senescence functions as a prognostic and therapeutic indicator in meningiomas
Single-cell RNA sequencing reveals cellular senescence functions as a prognostic and therapeutic indicator in meningiomas Open
Meningiomas rank among the most prevalent solid tumors in the human central nervous system, exhibiting a wide spectrum of prognoses, with particularly challenging outcomes in cases of malignant meningiomas. Cellular senescence (CS) is reco…
View article: Study on the meshing theory of the ring-shaped roller screw mechanism
Study on the meshing theory of the ring-shaped roller screw mechanism Open
Based on the structural characteristics of ring-shaped roller screw mechanism (RRSM), helical equations of the screw, roller and nut are derived. Meshing equations at the screw-roller and nut-roller interfaces are developed, which can be u…
View article: Epithelial–Mesenchymal Transition Expression Profile Stratifies Human Glioma into Two Distinct Tumor-Immune Subtypes
Epithelial–Mesenchymal Transition Expression Profile Stratifies Human Glioma into Two Distinct Tumor-Immune Subtypes Open
Glioma is the primary tumor with the highest incidence and the worst prognosis in the human central nervous system. Epithelial–mesenchymal transition (EMT) and immune responses are two crucial processes that contribute to it having the wor…
View article: Efficacy and Safety of Bevacizumab for Treating Glioblastoma: A Systematic Review and Meta-Analysis of Phase II and III Randomized Controlled Trials
Efficacy and Safety of Bevacizumab for Treating Glioblastoma: A Systematic Review and Meta-Analysis of Phase II and III Randomized Controlled Trials Open
To fully investigate the efficacy and safety of bevacizumab for glioblastoma. Databases were searched for phase II/III randomized controlled trials treated with bevacizumab. Bevacizumab significantly improved the PFS in glioblastoma patien…
View article: Efficacy and Safety of Bevacizumab for Treating Glioblastoma: A Systematic Review and Meta-Analysis of Phase II and III Randomized Controlled Trials
Efficacy and Safety of Bevacizumab for Treating Glioblastoma: A Systematic Review and Meta-Analysis of Phase II and III Randomized Controlled Trials Open
To fully investigate the efficacy and safety of bevacizumab for glioblastoma. Databases were searched for phase II/III randomized controlled trials treated with bevacizumab. Bevacizumab significantly improved the PFS in glioblastoma patien…
View article: Systematic Review and Meta-Analysis: Association between Preoperative Ustekinumab and Surgical Complications in Crohn’s Disease Patients
Systematic Review and Meta-Analysis: Association between Preoperative Ustekinumab and Surgical Complications in Crohn’s Disease Patients Open
Introduction: The impact of ustekinumab (UST) therapy on surgical complications in patients with Crohn’s disease (CD) remains controversial. The aim of this meta-analysis is to explore the link between these two. Methods: Databases (PubMed…
View article: Preload Mechanism of the Double-nut Planetary Roller Screw Mechanism with Pins
Preload Mechanism of the Double-nut Planetary Roller Screw Mechanism with Pins Open
：In order to use the planetary roller screw mechanism (PRSM) to achieve the high precision transmission at the forward and reverse directions, the study of the preloaded PRSM is urgently needed.A double-nut PRSM with pins is developed, whi…
View article: Ideological and Political Education of Minority Students Based on Network Information Security Model
Ideological and Political Education of Minority Students Based on Network Information Security Model Open
Education is the basis of promoting the process of national unity and development.The educational model of colleges and universities is constantly changing.But it also faces many challenges.How to effectively implement the work of national…
View article: Clinical Characteristics and Prognostic Risk Factors of Parasellar Chondrosarcoma
Clinical Characteristics and Prognostic Risk Factors of Parasellar Chondrosarcoma Open
Background: Parasellar chondrosarcomas are extremely rare. This study describes the characteristics of parasellar chondrosarcoma and analyzes the risk factors and prognosis based on the resection degree. Methods: Fifteen patients with path…
View article: Review on Motion and Load-Bearing Characteristics of the Planetary Roller Screw Mechanism
Review on Motion and Load-Bearing Characteristics of the Planetary Roller Screw Mechanism Open
Studying the motion and load-bearing characteristics of the planetary roller screw mechanism is the basis for the structural design and performance optimisation of the mechanism. The mechanical structures and working principles of differen…
View article: A dynamic separable convolution RCNN for lubrication condition identification of planetary roller screw mechanism
A dynamic separable convolution RCNN for lubrication condition identification of planetary roller screw mechanism Open
Lubrication condition has a strong effect on the service ability of planetary roller screw mechanism (PRSM), so how to effectively identify the lubrication condition of PRSM is highly important in practical industrial applications. A dynam…
View article: Go with the Flow? A Large-Scale Analysis of Health Care Delivery\n Networks in the United States Using Hodge Theory
Go with the Flow? A Large-Scale Analysis of Health Care Delivery\n Networks in the United States Using Hodge Theory Open
Health care delivery is a collaborative process, requiring close coordination\namong networks of providers with specialized expertise. Yet in the United\nStates, care is often spread across multiple disconnected providers (e.g.,\nprimary c…
View article: Lagrange-method-based dynamic analysis of multi-stage planetary roller screw mechanism
Lagrange-method-based dynamic analysis of multi-stage planetary roller screw mechanism Open
A rigid-body dynamic model of multi-stage planetary roller screw mechanism (multi-stage PRSM) is proposed in this paper. The structure of multi-stage PRSM is introduced and the motion analysis is presented. The total kinetic energy of the …
View article: Based on a Self-Feeder Layer, a Novel 3D Culture Model of Human ADSCs Facilitates Trans-Differentiation of the Spheroid Cells into Neural Progenitor-Like Cells Using siEID3 with a Laminin/Poly-d-lysine Matrix
Based on a Self-Feeder Layer, a Novel 3D Culture Model of Human ADSCs Facilitates Trans-Differentiation of the Spheroid Cells into Neural Progenitor-Like Cells Using siEID3 with a Laminin/Poly-d-lysine Matrix Open
Human adipose-derived stromal cells (ADSCs) are receiving unprecedented attention as a potential cellular source for regenerative medicine-based therapies against various diseases and conditions. However, there still have significant issue…