Xian‐Zhang Hu
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View article: Preexisting Depression and Prostate Cancer Survival
Preexisting Depression and Prostate Cancer Survival Open
This cohort study evaluates whether there are survival differences between patients with prostate cancer with vs without preexisting depression.
View article: The Central Role of Cytokines in PTSD and Major Depressive Disorder: Mechanisms and Clinical Implications
The Central Role of Cytokines in PTSD and Major Depressive Disorder: Mechanisms and Clinical Implications Open
View article: Third-degree atrioventricular block induced by escitalopram and quetiapine in a patient with depression: a case report
Third-degree atrioventricular block induced by escitalopram and quetiapine in a patient with depression: a case report Open
Third-degree atrioventricular block (AVB) associated with the use of escitalopram and quetiapine is rare, with limited cases reported. We present a case of drug-induced third-degree AVB in an elderly patient undergoing treatment for depres…
View article: Intelligent Unmanned Defense System for Autonomous Interception of UAVs Based on Improved Acoustic Source Localization Algorithm
Intelligent Unmanned Defense System for Autonomous Interception of UAVs Based on Improved Acoustic Source Localization Algorithm Open
Illegal flights of UAVs have seriously threatened personal privacy and social security. UAV localization techniques, especially acoustic source localization, have received extensive attention from scholars. However, the traditional acousti…
View article: Association of 5-HTTLPR With Post-Traumatic Stress Disorder in US Service Members
Association of 5-HTTLPR With Post-Traumatic Stress Disorder in US Service Members Open
Objective Post-traumatic stress disorder (PTSD) is a mental disorder that manifests after exposure to a stressful traumatic event, such as combat experience. Accumulated evidence indicates an important genetic influence in the development …
View article: Mitochondrial gene expression profiles in PTG in the Amygdala of a PTSD Model Following Corticosterone Therapy
Mitochondrial gene expression profiles in PTG in the Amygdala of a PTSD Model Following Corticosterone Therapy Open
The metabolic and neuronal mechanisms underlying the development of posttraumatic growth (PTG) following corticosterone (CORT) therapy in patients with posttraumatic stress disorder (PTSD) are not well defined. In this study, we assess dif…
View article: Left Amygdala Functional Connectivity Decreased after Fear of Negative Events was Disregarded in Obsessive-Compulsive Disorder
Left Amygdala Functional Connectivity Decreased after Fear of Negative Events was Disregarded in Obsessive-Compulsive Disorder Open
Obsessive-compulsive disorder (OCD) is a chronic and debilitating mental disorder that affects patients throughout their lives, leading to a diminished quality of life for patients and families, reduced productivity, and higher health care…
View article: Chemokines as Potential Biomarkers for PTSD in Military Population
Chemokines as Potential Biomarkers for PTSD in Military Population Open
Post-traumatic stress disorder (PTSD) is a serious mental health concern worldwide among civilians and military personnel. Gaps in our understanding of its biological basis create significant obstacles for accurate diagnosis and assessment…
View article: Effects of short‐term cognitive‐coping therapy on resting‐state brain function in obsessive‐compulsive disorder
Effects of short‐term cognitive‐coping therapy on resting‐state brain function in obsessive‐compulsive disorder Open
Background Obsessive‐compulsive disorder (OCD) tends to be treatment refractory. Recently, cognitive‐coping therapy (CCT) for OCD is reported to be an efficacious psychotherapy. However, the underlying neurophysiological mechanism remains …
View article: Effects of the COVID-19 Pandemic on Obsessive-Compulsive Symptoms Among University Students: Prospective Cohort Survey Study
Effects of the COVID-19 Pandemic on Obsessive-Compulsive Symptoms Among University Students: Prospective Cohort Survey Study Open
Background The COVID-19 pandemic is associated with common mental health problems. However, evidence for the association between fear of COVID-19 and obsessive-compulsive disorder (OCD) is limited. Objective This study aimed to examine if …
View article: Effects of the COVID-19 Pandemic on Obsessive-Compulsive Symptoms Among University Students: Prospective Cohort Survey Study (Preprint)
Effects of the COVID-19 Pandemic on Obsessive-Compulsive Symptoms Among University Students: Prospective Cohort Survey Study (Preprint) Open
BACKGROUND The COVID-19 pandemic is associated with common mental health problems. However, evidence for the association between fear of COVID-19 and obsessive-compulsive disorder (OCD) is limited. OBJECTIVE This study aimed to examine …
View article: Potential chemokine biomarkers associated with PTSD onset, risk and resilience as well as stress responses in US military service members
Potential chemokine biomarkers associated with PTSD onset, risk and resilience as well as stress responses in US military service members Open
Cytokines, including chemokines, are small secreted proteins, which specifically effect on the interactions and communications between cells. Pro-inflammatory cytokines are produced predominantly by activated macrophages and are involved i…
View article: Association of Telomere Length, a Cellular Aging Marker, with Depression, PTSD and Hostility
Association of Telomere Length, a Cellular Aging Marker, with Depression, PTSD and Hostility Open
Depression, PTSD, and hostility are common mental conditions that are associated with aging. A growing body of research has highlighted the possible effects of depression, PTSD, and hostility on aging and telomere length (TL), a cellular a…
View article: EXISTENTIAL SUFFERING AND PSYCHOLOGICAL SYMPTOMS AMONG DEMENTIA CAREGIVERS RECEIVING COLLABORATIVE CARE
EXISTENTIAL SUFFERING AND PSYCHOLOGICAL SYMPTOMS AMONG DEMENTIA CAREGIVERS RECEIVING COLLABORATIVE CARE Open
The presence of suffering and psychological strain among dementia family caregivers is well-documented. Literature highlights successful interventions aimed at reducing these outcomes. One evidence-based intervention that has been translat…
View article: Probable involvement of p11 with interferon alpha induced depression
Probable involvement of p11 with interferon alpha induced depression Open
Depression is one of the major side effects of interferon alpha (IFN-α) treatment, but the molecular mechanism underlying IFN-α-induced depression remains unclear. Several studies have shown that the serotonin receptors 5-HTR1b and 5-HTR4 …
View article: Post-traumatic stress disorder risk and brain-derived neurotrophic factor Val66Met
Post-traumatic stress disorder risk and brain-derived neurotrophic factor Val66Met Open
Brain-derived neurotrophic factor (BDNF), which regulates neuronal survival, growth differentiation, and synapse formation, is known to be associated with depression and post-traumatic stress disorder (PTSD). However, the molecular mechani…
View article: Posttraumatic Stress Disorder Biomarker — p11
Posttraumatic Stress Disorder Biomarker — p11 Open
Post-traumatic stress disorder (PTSD) is a chronic and disabling anxiety disorder associated with a traumatic event [1]. It is linked to increased risk of suicide and deficits in social functioning [2, 3]. Despite extensive study in psychi…
View article: Mitochondria-focused gene expression profile reveals common pathways and CPT1B dysregulation in both rodent stress model and human subjects with PTSD
Mitochondria-focused gene expression profile reveals common pathways and CPT1B dysregulation in both rodent stress model and human subjects with PTSD Open
Posttraumatic stress disorder (PTSD), a trauma-related mental disorder, is associated with mitochondrial dysfunction in the brain. However, the biologic approach to identifying the mitochondria-focused genes underlying the pathogenesis of …