Xiao Guan
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View article: SEL1L confers reduced EMT and drug resistance to breast cancer cells by promoting Shh degradation
SEL1L confers reduced EMT and drug resistance to breast cancer cells by promoting Shh degradation Open
Summary: The expression of SEL1L (suppressor/enhancer of Lin-12-like) is found to be downregulated in clinical breast cancer (BRC) and lymph node metastasis tissues, as well as in carboplatin-resistant BRC cell lines. In this study, reduce…
View article: Time-marching multi-level variational multiscale tensor decomposition algorithm for heat conduction with moving heat source
Time-marching multi-level variational multiscale tensor decomposition algorithm for heat conduction with moving heat source Open
In this paper, we propose a time-marching multi-level Variational Multiscale-Tensor Decomposition (VMS-TD) algorithm to solve the heat equation with a moving heat source model that arises from additive manufacturing. First, we take a secon…
View article: Release and transformation patterns of polyphenols of rice at different milling degrees during in vitro gastrointestinal digestion and colonic fermentation
Release and transformation patterns of polyphenols of rice at different milling degrees during in vitro gastrointestinal digestion and colonic fermentation Open
View article: An Autonomous Mobile Measurement Method for Key Feature Points in Complex Aircraft Assembly Scenes
An Autonomous Mobile Measurement Method for Key Feature Points in Complex Aircraft Assembly Scenes Open
Large-scale measurement of key feature points (KFPs) on an aircraft is essential for coordinated movement of locators, which is critical to the final assembly accuracy. Due to the large number and wide distribution of KFPs as well as line-…
View article: Neoadjuvant immunotherapy driven bladder preservation for muscle invasive bladder cancer
Neoadjuvant immunotherapy driven bladder preservation for muscle invasive bladder cancer Open
View article: Millet Quinic Acid Relieves Colitis by Regulating Gut Microbiota and Inhibiting MyD88/NF-κB Signaling Pathway
Millet Quinic Acid Relieves Colitis by Regulating Gut Microbiota and Inhibiting MyD88/NF-κB Signaling Pathway Open
Polyphenols are compounds derived from plant-based food possessing numerous biological activities, including inhibiting oxidative stress, suppressing inflammation, and regulating gut microbiota. In this study, we investigated the effects o…
View article: The impact of salt-tolerant plants on soil nutrients and microbial communities in soda saline-alkali lands of the Songnen plain
The impact of salt-tolerant plants on soil nutrients and microbial communities in soda saline-alkali lands of the Songnen plain Open
Introduction Soil salinization poses a significant threat to agricultural development and ecosystem health. While phytoremediation is an effective approach, the mechanisms by which salt-tolerant plants mediate saline-alkali soil ameliorati…
View article: Characterization of key flavor components in flavor enhanced rice bran oil prepared by high-pressure steamed bran
Characterization of key flavor components in flavor enhanced rice bran oil prepared by high-pressure steamed bran Open
View article: Research on Strategies to Enhance Kindergarten Teachers' Ability to Create Garden-Based Programs
Research on Strategies to Enhance Kindergarten Teachers' Ability to Create Garden-Based Programs Open
The improvement of kindergarten teachers' ability to create garden-based curriculum helps kindergarten's curriculum development, also helps teachers' professionalism sublimation, and helps to promote children's all-round development. This …
View article: Propanoic Acid-Functionalized Chitosan Decorated Liposomes for Enhanced Oral Delivery and Hypoglycemic Effect of Insulin
Propanoic Acid-Functionalized Chitosan Decorated Liposomes for Enhanced Oral Delivery and Hypoglycemic Effect of Insulin Open
View article: SEL1L Confers Reduced EMT and Carboplatin Resistance to Triple-Negative Breast Cancer Cells by Promoting Shh Degradation
SEL1L Confers Reduced EMT and Carboplatin Resistance to Triple-Negative Breast Cancer Cells by Promoting Shh Degradation Open
View article: Long Chain Fatty Acids Modified Liposomes Provide Controlled Release and Enhanced Intestinal Permeation of Bioactive Peptides
Long Chain Fatty Acids Modified Liposomes Provide Controlled Release and Enhanced Intestinal Permeation of Bioactive Peptides Open
View article: Oat Dietary Fiber Attenuated Chronic Kidney Disease Via Inhibiting Gut Derived Metabolites-Induced TGF-β1/Smad Activation: A Perspective from Gut-Kidney Axis
Oat Dietary Fiber Attenuated Chronic Kidney Disease Via Inhibiting Gut Derived Metabolites-Induced TGF-β1/Smad Activation: A Perspective from Gut-Kidney Axis Open
View article: Advances in the Production of Emulsifying Pea Protein Isolates with the Oat Β-Glucan Glycosylation
Advances in the Production of Emulsifying Pea Protein Isolates with the Oat Β-Glucan Glycosylation Open
View article: Development of an Integrated Multifunctional Column for Rapid Pretreatment and Determination of Trichothecenes in Cereals and Feeds with Hplc Ms/Ms
Development of an Integrated Multifunctional Column for Rapid Pretreatment and Determination of Trichothecenes in Cereals and Feeds with Hplc Ms/Ms Open
View article: Synergistic Effects of Inhibitors on Color Stability and Flavor Retention Mechanisms in Ambient-Stored Mashed Potatoes
Synergistic Effects of Inhibitors on Color Stability and Flavor Retention Mechanisms in Ambient-Stored Mashed Potatoes Open
View article: Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis
Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis Open
View article: Variant pathogenicity prediction based on the ESGMM algorithm
Variant pathogenicity prediction based on the ESGMM algorithm Open
View article: An Updated Review on the Mechanisms, Pre‐Clinical and Clinical Comparisons of Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR)
An Updated Review on the Mechanisms, Pre‐Clinical and Clinical Comparisons of Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR) Open
The study of nicotinamide adenine dinucleotide (NAD + ) biology has gained popularity recently. Research discovered that two NAD + biosynthesis intermediates, nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), are biosynthet…
View article: Oat arabinoxylan promoted <i>Lactobacillus gasseri</i> to alleviate metabolic disorders in high-fat diet-induced obese mice
Oat arabinoxylan promoted <i>Lactobacillus gasseri</i> to alleviate metabolic disorders in high-fat diet-induced obese mice Open
Arabinoxylan (AX) has been found to improve an imbalanced gut microbiota. Lactobacillus gasseri is a beneficial endogenous bacterium that has been shown to have several health benefits in the human gut, particularly its lipid-lowering acti…
View article: Quinic acid alleviates high-fat diet-induced neuroinflammation by inhibiting DR3/IKK/NF-κB signaling via gut microbial tryptophan metabolites
Quinic acid alleviates high-fat diet-induced neuroinflammation by inhibiting DR3/IKK/NF-κB signaling via gut microbial tryptophan metabolites Open
With the increasing of aging population and the consumption of high-fat diets (HFD), the incidence of Alzheimer's disease (AD) has skyrocketed. Natural antioxidants show promising potential in the prevention of AD, as oxidative stress and …
View article: Oat avenanthramide B alleviates high-fat diet-induced obesity via regulating fatty acid metabolism involved in gut bacteria and fungi remodeling
Oat avenanthramide B alleviates high-fat diet-induced obesity via regulating fatty acid metabolism involved in gut bacteria and fungi remodeling Open
Oat avenanthramides (AVNs) have been found to exhibit novel lipid-lowering effects. However, the mechanism remains unclear. In this study, the effect of avenanthramide B (AVN B), as one of the major AVNs, on high-fat diet (HFD)-induced mic…
View article: Variant pathogenicity prediction based on the ESGMM algorithm
Variant pathogenicity prediction based on the ESGMM algorithm Open
Modeling the functional impact of sequence variation is a critical issue for both understanding and developing proteins. An Evolutionary Sequence and Gaussian Mixture Model (ESGMM) for predicting variant pathogenicity is presented in this …
View article: L-lysine dietary supplementation for childhood and adolescent growth: Promises and precautions
L-lysine dietary supplementation for childhood and adolescent growth: Promises and precautions Open
View article: Fabrication of diosmin loaded food-grade bilayer nanoparticles with modified chitosan and soy peptides and antioxidant properties examination
Fabrication of diosmin loaded food-grade bilayer nanoparticles with modified chitosan and soy peptides and antioxidant properties examination Open
Diosmin is a flavonoid derived from plants, possessing anti-inflammatory, antioxidant, antidiabetic, neuroprotective and cardiovascular protective properties. However, diosmin has low solubility in water, leading to low bioavailability. In…
View article: Exploring the Therapeutic Potential of Royal Jelly in Metabolic Disorders and Gastrointestinal Diseases
Exploring the Therapeutic Potential of Royal Jelly in Metabolic Disorders and Gastrointestinal Diseases Open
Metabolic disorders, encompassing diabetes mellitus, cardiovascular diseases, gastrointestinal disorders, etc., pose a substantial global health threat, with rising morbidity and mortality rates. Addressing these disorders is crucial, as c…
View article: Semi-quantitative analysis of key aroma compounds in fragrant rice bran oil by GC×GC- TOFMS and GC-O
Semi-quantitative analysis of key aroma compounds in fragrant rice bran oil by GC×GC- TOFMS and GC-O Open
The physicochemical and flavor qualities of three types of rice bran oil (RBO) were explored, namely RBO A (rice aroma RBO), RBO B (pressed RBO), and RBO C (refined RBO). Various analyses were employed to critically evaluate the flavor pro…
View article: Enhancing the Texture and Modulating Digestive Behavior of Gluten-Free Quinoa Sponge Cakes Via Microwave-Assisted Alkaline Amino Acid Treatment
Enhancing the Texture and Modulating Digestive Behavior of Gluten-Free Quinoa Sponge Cakes Via Microwave-Assisted Alkaline Amino Acid Treatment Open
View article: Predicting multifunctional peptides based on a multi-scale ResNet model combined with channel attention mechanisms
Predicting multifunctional peptides based on a multi-scale ResNet model combined with channel attention mechanisms Open
Peptides are biomolecules composed of multiple amino acid residues connected by peptide bonds, which are widely involved in physiological and biochemical processes in organisms and exhibit diverse functions. In previous studies, the focus…
View article: Palmitic Acid Modified Liposomes for Encapsulation of Bioactive Peptides: Characterization, Storage Stability and Intestinal Absorption
Palmitic Acid Modified Liposomes for Encapsulation of Bioactive Peptides: Characterization, Storage Stability and Intestinal Absorption Open