Xiaoli Gao
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View article: Prognostic and clinicopathological value of fibrinogen-to-albumin ratio in patients with esophageal cancer: a meta-analysis
Prognostic and clinicopathological value of fibrinogen-to-albumin ratio in patients with esophageal cancer: a meta-analysis Open
View article: Prognostic and clinicopathological value of fibrinogen-to-albumin ratio in patients with esophageal cancer: A meta-analysis
Prognostic and clinicopathological value of fibrinogen-to-albumin ratio in patients with esophageal cancer: A meta-analysis Open
View article: Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk
Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk Open
Background Horse milk is a highly valuable organic food that is a promising alternative to cow milk, exhibiting plenty of healthy and immune benefits to human. However, identification of proteins associated human wellness and underlying mo…
View article: Adaptive Thermogenesis and Lipid Metabolism Modulation in Inguinal and Perirenal Adipose Tissues of Hezuo Pigs in Response to Low-Temperature Exposure
Adaptive Thermogenesis and Lipid Metabolism Modulation in Inguinal and Perirenal Adipose Tissues of Hezuo Pigs in Response to Low-Temperature Exposure Open
In mammals, exposure to low temperatures induces white adipose tissue (WAT) browning and alters lipid metabolism to promote thermogenesis, thereby maintaining body temperature. However, this response varies across different adipose depots.…
View article: Development and Validation of an Automated Tmpfc Analysis Pipeline for Noninvasive Myocardial Microcirculation Assessment
Development and Validation of an Automated Tmpfc Analysis Pipeline for Noninvasive Myocardial Microcirculation Assessment Open
View article: Trends and frontiers of RNA methylation in cancer over the past 10 years: a bibliometric and visual analysis
Trends and frontiers of RNA methylation in cancer over the past 10 years: a bibliometric and visual analysis Open
Purpose To highlight the trends and frontiers of RNA methylation in cancer over the past 10 years. Methods Research publications on RNA methylation in cancer were retrieved from the Web of Science Core Collection database. VOSviewer, CiteS…
View article: Pig Milk Exosome Packaging ssc-miR-22-3p Alleviates Pig Intestinal Epithelial Cell Injury and Inflammatory Response by Targeting MAPK14
Pig Milk Exosome Packaging ssc-miR-22-3p Alleviates Pig Intestinal Epithelial Cell Injury and Inflammatory Response by Targeting MAPK14 Open
Inflammatory diseases of the intestinal tract in piglets severely impair the economic performance of pig farms. Pig milk exosomes can encapsulate miRNAs which can then enter the piglet intestine to play an immunomodulatory role. Previously…
View article: Minor Humulane and Eremophilane Sesquiterpenoids from <i>Syringa pinnatifolia</i> and Their Protective Effect Against Oxidative Injuries in H9c2 Cells
Minor Humulane and Eremophilane Sesquiterpenoids from <i>Syringa pinnatifolia</i> and Their Protective Effect Against Oxidative Injuries in H9c2 Cells Open
As a part of systematic research, an ongoing phytochemical investigation of the sesquiterpenoid‐containing fraction led to the isolation of five new sesquiterpenoids from the peeled stems of Syringa pinnatifolia , including two pairs of en…
View article: Mining and exploration of appendicitis nursing targets: An observational study
Mining and exploration of appendicitis nursing targets: An observational study Open
Appendicitis is an inflammation caused by obstruction of the appendiceal lumen or termination of blood supply leading to appendiceal necrosis followed by secondary bacterial infection. The relationship between TYROBP gene and the nursing o…
View article: Mapping the intellectual structure and emerging trends for the application of nanomaterials in gastric cancer: A bibliometric study
Mapping the intellectual structure and emerging trends for the application of nanomaterials in gastric cancer: A bibliometric study Open
BACKGROUND Recent reviews have outlined the main nanomaterials used in relation to gastrointestinal tumors and described the basic properties of these materials. However, the research hotspots and trends in the application of nanomaterials…
View article: MYC and NCAPG2 as molecular targets of colorectal cancer and gastric cancer in nursing
MYC and NCAPG2 as molecular targets of colorectal cancer and gastric cancer in nursing Open
Colorectal cancer is a common malignant tumor in intestinal tract, the early symptoms are not obvious. Gastric cancer is a malignant tumor originating from the gastric mucosal epithelium. However, the role of MYC and non-SMC condensin II c…
View article: Clinical Features and Outcomes of Twin Pregnancies with Antiphospholipid Antibodies Positivity: A Retrospective Study
Clinical Features and Outcomes of Twin Pregnancies with Antiphospholipid Antibodies Positivity: A Retrospective Study Open
Twin pregnancies with aPL positivity were correlated with obstetric complications, including abortion, preterm birth < 34 weeks and very low birthweight (<1500 g). The detection of aPL may be of clinical significance for women with twin pr…
View article: Transcriptome analysis on pulmonary inflammation between periodontitis and COPD
Transcriptome analysis on pulmonary inflammation between periodontitis and COPD Open
Lcn2, S100a8, S100a9, Irg1, Clec4d are potential crossover genes of periodontal disease and COPD. Lcn2, S100a8, S100a9 are correlated with neutrophils in both diseases. Irg1 and Clec4d may bind to receptors on the surface of lymphocytes to…
View article: Analysis of factors related to thrombosis in patients with PICC placements
Analysis of factors related to thrombosis in patients with PICC placements Open
This study aimed to investigate the conditions of patients with peripherally inserted central catheter (PICC) placements, analyze the risk factors influencing thrombosis in PICC-placed patients, and formulate more accurate and effective PI…
View article: Breed-Related Differential microRNA Expression and Analysis of Colostrum and Mature Milk Exosomes in Bamei and Landrace Pigs
Breed-Related Differential microRNA Expression and Analysis of Colostrum and Mature Milk Exosomes in Bamei and Landrace Pigs Open
Breast milk, an indispensable source of immunological and nutrient components, is essential for the growth and development of newborn mammals. MicroRNAs (miRNAs) are present in various tissues and body fluids and are selectively packaged i…
View article: Atg5 Gene Regulates Testosterone Production of Testicular Leydig Cells in Hezuo Pig
Atg5 Gene Regulates Testosterone Production of Testicular Leydig Cells in Hezuo Pig Open
View article: Genome-Wide Identification and Expression Analysis Reveals the B3 Superfamily Involved in Embryogenesis and Hormone Responses in Dimocarpus longan Lour.
Genome-Wide Identification and Expression Analysis Reveals the B3 Superfamily Involved in Embryogenesis and Hormone Responses in Dimocarpus longan Lour. Open
B3 family transcription factors play an essential regulatory role in plant growth and development processes. This study performed a comprehensive analysis of the B3 family transcription factor in longan (Dimocarpus longan Lour.), and a tot…
View article: Regulatory Effects of the Kiss1 Gene in the Testis on Puberty and Reproduction in Hezuo and Landrance Boars
Regulatory Effects of the Kiss1 Gene in the Testis on Puberty and Reproduction in Hezuo and Landrance Boars Open
Kisspeptin, a neuropeptide encoded by the Kiss1 gene, combines with its receptor Kiss1R to regulate the onset of puberty and male fertility by the hypothalamic–pituitary–gonadal axis. However, little is known regarding the expression signa…
View article: Pregnancy in women with autosomal recessive Alport syndrome caused by novel compound heterozygous mutations of COL4A3 gene: Two cases reports
Pregnancy in women with autosomal recessive Alport syndrome caused by novel compound heterozygous mutations of COL4A3 gene: Two cases reports Open
Rationale: Autosomal recessive Alport syndrome (ARAS) is an hereditary heterogeneous disease that poses a serious risk to pregnant women. Patient concerns: We reported 2 cases of pregnancy with progressive proteinuria. The case 1 was a 21-…
View article: Nitrogen fertilizer affects the cooking quality and starch properties of proso millet (<i>Panicum miliaceum</i> L.)
Nitrogen fertilizer affects the cooking quality and starch properties of proso millet (<i>Panicum miliaceum</i> L.) Open
Nitrogen has a critical influence on the yield and quality of proso millet. However, the exact impact of nitrogen on the cooking quality of proso millet is not clear. In this study, the cooking quality and starch properties of two proso mi…
View article: Transcription factors NF-YB involved in embryogenesis and hormones responses in Dimocarpus Longan Lour
Transcription factors NF-YB involved in embryogenesis and hormones responses in Dimocarpus Longan Lour Open
Introduction NF-YB transcription factor is an important regulatory factor in plant embryonic development. Results In this study, 15 longan NF-YB ( DlNF-YB ) family genes were systematically identified in the whole genome of longan, and a c…
View article: Mapping of major QTL and candidate gene analysis for hull colour in foxtail millet (Setaria italica (L.) P. Beauv.)
Mapping of major QTL and candidate gene analysis for hull colour in foxtail millet (Setaria italica (L.) P. Beauv.) Open
Background Hull colour is an important morphological marker for selection in seed production of foxtail millet. However, the molecular mechanisms underlying hull colour variation remain unknown. Results An F 7 recombinant inbred line (RIL)…
View article: Preparation and In Vitro Characterization of Microneedles Containing Inclusion Complexes Loaded with Progesterone
Preparation and In Vitro Characterization of Microneedles Containing Inclusion Complexes Loaded with Progesterone Open
Objective: In order to improve patient compliance and the ease of use during progesterone application, and to increase the clinical application of progesterone, progesterone was made into a microneedle. Methods: Progesterone complexes were…
View article: Serum metabolic signatures for acute pulmonary embolism identified by untargeted metabolomics
Serum metabolic signatures for acute pulmonary embolism identified by untargeted metabolomics Open
Background and aims The important metabolic features of acute pulmonary embolism (APE) risk stratification and their underlying biological basis remain elusive. Our study aims to develop early diagnostic models and classification models by…
View article: Identification of a Novel lncRNA LNC_001186 and Its Effects on CPB2 Toxin-Induced Apoptosis of IPEC-J2 Cells
Identification of a Novel lncRNA LNC_001186 and Its Effects on CPB2 Toxin-Induced Apoptosis of IPEC-J2 Cells Open
The Clostridium perfringens (C. perfringen) beta2 (CPB2) toxin produced by C. perfringens type C (CpC) can cause necrotizing enteritis in piglets. Immune system activation in response to inflammation and pathogen infection is aided by long…
View article: Identification of MicroRNAs Regulating Clostridium perfringens Type C Infection in the Spleen of Diarrheic Piglets
Identification of MicroRNAs Regulating Clostridium perfringens Type C Infection in the Spleen of Diarrheic Piglets Open
Clostridium perfringens (C. perfringens) type C is one of the common bacteria in piglet diarrhea, which seriously affects the swine industry’s development. The spleen plays crucial roles in the resistance and elimination of pathogenic micr…
View article: Dental Pulp Stem Cells Ameliorate Elastase-Induced Pulmonary Emphysema by Regulating Inflammation and Oxidative Stress
Dental Pulp Stem Cells Ameliorate Elastase-Induced Pulmonary Emphysema by Regulating Inflammation and Oxidative Stress Open
The current study showed that DPSCs had good performance in the treatment of a mouse COPD model and could be a promising option for stem cell therapy. DPSCs may play antioxidant and anti-inflammatory roles in COPD by activating the Nrf2 si…
View article: lnc001776 Affects CPB2 Toxin-Induced Excessive Injury of Porcine Intestinal Epithelial Cells via Activating JNK/NF-kB Pathway through ssc-let-7i-5p/IL-6 Axis
lnc001776 Affects CPB2 Toxin-Induced Excessive Injury of Porcine Intestinal Epithelial Cells via Activating JNK/NF-kB Pathway through ssc-let-7i-5p/IL-6 Axis Open
Piglet diarrhea caused by Clostridium perfringens (C. perfringens) type C (CpC) seriously endangers the development of the pig production industry. C. perfringens beta2 (CPB2) toxin is a virulent toxin produced by CpC. Long non-coding RNAs…
View article: The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway
The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway Open
Background There is a characteristic Tibetan folk medicine in China named Corydalis hendersonii Hemsl. (CH) has been used for treatment of cardiovascular related diseases, called “plethora” in Tibetan medicine. Previous studies demonstrate…
View article: METTL3-Mediated LncRNA EN_42575 m6A Modification Alleviates CPB2 Toxin-Induced Damage in IPEC-J2 Cells
METTL3-Mediated LncRNA EN_42575 m6A Modification Alleviates CPB2 Toxin-Induced Damage in IPEC-J2 Cells Open
Long non-coding RNAs (lncRNAs) modified by n6-methyladenosine (m6A) have been implicated in the development and progression of several diseases. However, the mechanism responsible for the role of m6A-modified lncRNAs in Clostridium perfrin…