Xiaoli Li
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View article: A near-complete genome assembly of cucumber line 6457 and identification of candidate gene controlling pedicel length
A near-complete genome assembly of cucumber line 6457 and identification of candidate gene controlling pedicel length Open
View article: Optimization, comparison and mechanism of ultrasound-assisted cellulase hydrolysis and ethanol extraction of quercetin, luteolin and apigenin from male inflorescences of Populus alba × berolinensis
Optimization, comparison and mechanism of ultrasound-assisted cellulase hydrolysis and ethanol extraction of quercetin, luteolin and apigenin from male inflorescences of Populus alba × berolinensis Open
In this study, we aimed to determine the optimal process parameters for extracting quercetin, luteolin and apigenin from the male inflorescences of Populus alba × berolinensis via the ultrasound-assisted cellulase hydrolysis and ethanol ex…
View article: Mechanism of Melatonin in Alleviating Aluminum Toxicity in Plants: A Review
Mechanism of Melatonin in Alleviating Aluminum Toxicity in Plants: A Review Open
Aluminum (Al) toxicity is a major limiting factor for plant growth and development in acidic soils. Melatonin, a plant growth regulator and signaling molecule, enhances resistance to multiple stresses. Recent studies show that melatonin al…
View article: Artificial Intelligence Model for Accurate Grading and Staging of Chronic Hepatitis B: Development and Validation
Artificial Intelligence Model for Accurate Grading and Staging of Chronic Hepatitis B: Development and Validation Open
Background and aims: Chronic hepatitis B (CHB) is a global challenge, with histological assessment affected by observer variability. We aim to develop and validate BJ-HepaGS, an AI model for consistent evaluation. Methods: BJ-HepaGS was de…
View article: Memorization $\neq$ Understanding: Do Large Language Models Have the Ability of Scenario Cognition?
Memorization $\neq$ Understanding: Do Large Language Models Have the Ability of Scenario Cognition? Open
Driven by vast and diverse textual data, large language models (LLMs) have demonstrated impressive performance across numerous natural language processing (NLP) tasks. Yet, a critical question persists: does their generalization arise from…
View article: XFEM for the diffusion and sub-diffusion problems in a non-convex domain
XFEM for the diffusion and sub-diffusion problems in a non-convex domain Open
View article: Neural mechanism of conscious perception for potential clinical applications
Neural mechanism of conscious perception for potential clinical applications Open
View article: Parietal <scp>rTMS</scp> Induced Changes in Cortical Excitability in Patients With Minimally Conscious State Using <scp>TMS</scp>‐<scp>EEG</scp>
Parietal <span>rTMS</span> Induced Changes in Cortical Excitability in Patients With Minimally Conscious State Using <span>TMS</span>‐<span>EEG</span> Open
Objective To verify the effectiveness of the parietal repetitive transcranial magnetic stimulation (rTMS) and take advantage of TMS‐EEG to assess cortical excitability in patients with minimally conscious states (MCS). Methods We enrolled …
View article: TREK-1 and epilepsy: regulating the balance of K+ and the glutamate release in astrocyte-neuron interactions
TREK-1 and epilepsy: regulating the balance of K+ and the glutamate release in astrocyte-neuron interactions Open
The TWIK-related K + channel (TREK-1), a member of the two-pore domain potassium(K2P) family, is characterized as a “leaky potassium channel” and is integral to the maintenance of the resting membrane potential. As the most abundant cell t…
View article: Effects of Transcranial Direct Current Stimulation on Excitatory/Inhibitory Balance and Behavior in Children With Autism—A Randomized Controlled Study
Effects of Transcranial Direct Current Stimulation on Excitatory/Inhibitory Balance and Behavior in Children With Autism—A Randomized Controlled Study Open
Background: Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder marked by impaired interactions and restricted interests, the pathophysiology of which is not fully understood. The current study explored the potenti…
View article: The diagnostic value of long noncoding RNAs as a biomarker for in-stent restenosis in patients with coronary heart disease: A systematic review and meta-analysis of diagnostic test accuracy studies
The diagnostic value of long noncoding RNAs as a biomarker for in-stent restenosis in patients with coronary heart disease: A systematic review and meta-analysis of diagnostic test accuracy studies Open
Background: The diagnostic utility of long noncoding RNAs (lncRNAs) in detecting in-stent restenosis (ISR) among coronary heart disease (CHD) patients has drawn significant research interest. Despite this attention, however, only a limited…
View article: Targeting TNFAIP2 with NIR-II CRISPR-Cas9 nanosystem to overcome cisplatin resistance in laryngeal cancer
Targeting TNFAIP2 with NIR-II CRISPR-Cas9 nanosystem to overcome cisplatin resistance in laryngeal cancer Open
Cisplatin resistance is a major challenge in laryngeal cancer treatment. Tumor necrosis factor-alpha-induced protein 2 (TNFAIP2) has been implicated in chemoresistance, though its role in laryngeal cancer remains unclear. We identified TNF…
View article: A practical measure of integrated information reveals alpha-band activity and the posterior cortex as neural correlates of arousal
A practical measure of integrated information reveals alpha-band activity and the posterior cortex as neural correlates of arousal Open
The search for neurophysiological markers of consciousness and their neural substrates remains a focal point in neuroscience research. The integrated information theory (IIT) provides a promising quantitative framework for consciousness as…
View article: [A large family of Nascimento form of syndromic X-linked intellectual developmental disorder caused by large segment deletion of the <i>UBE2A</i> gene: a case report and literature review].
[A large family of Nascimento form of syndromic X-linked intellectual developmental disorder caused by large segment deletion of the <i>UBE2A</i> gene: a case report and literature review]. Open
This article reports the clinical features and gene mutation types of a large family with Nascimento form of syndromic X-linked intellectual developmental disorder (MRXSN), involving 9 individuals across 3 generations, and a literature rev…
View article: Age-Dependent Entropic Features During Propofol Anesthesia in Developing Brain
Age-Dependent Entropic Features During Propofol Anesthesia in Developing Brain Open
BACKGROUND: Precise monitoring of anesthetic depth in children receiving propofol anesthesia is crucial. Commercial depth of anesthesia monitoring devices do not account for age-related changes in brain states and provide misleading inform…
View article: State-Dependent Transcranial Magnetic Stimulation Synchronized with Electroencephalography: Mechanisms, Applications, and Future Directions
State-Dependent Transcranial Magnetic Stimulation Synchronized with Electroencephalography: Mechanisms, Applications, and Future Directions Open
Transcranial magnetic stimulation combined with electroencephalography (TMS-EEG) has emerged as a transformative tool for probing cortical dynamics with millisecond precision. This review examines the state-dependent nature of TMS-EEG, a c…
View article: Quantifying task-locked information transmission between cortical areas with TMS-EEG
Quantifying task-locked information transmission between cortical areas with TMS-EEG Open
View article: Donor-derived microbial engraftment and gut microbiota shifts associated with weight loss following fecal microbiota transplantation
Donor-derived microbial engraftment and gut microbiota shifts associated with weight loss following fecal microbiota transplantation Open
Fecal microbiota transplantation (FMT) is a promising treatment for microbiota dysbiosis and may provide metabolic benefits for obesity. However, its mechanisms and variability in clinical outcomes remain poorly understood. This 12-week mu…
View article: Neuroobserver‐Based Adaptive Output Control for Decentralized Systems Guaranteeing Transient Performance
Neuroobserver‐Based Adaptive Output Control for Decentralized Systems Guaranteeing Transient Performance Open
This work is focused on the neural adaptive output feedback control of decentralized uncertain nonlinear systems subject to bounded disturbance, unmodeled dynamics, and uncertainties. Specifically, pervasive and general decentralized syste…
View article: ABS1153 A PHASE 4, MULTICENTRE, OPEN-LABEL STUDY OF INTRAVENOUS BELIMUMAB IN PAEDIATRIC PATIENTS WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS IN CHINA
ABS1153 A PHASE 4, MULTICENTRE, OPEN-LABEL STUDY OF INTRAVENOUS BELIMUMAB IN PAEDIATRIC PATIENTS WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS IN CHINA Open
View article: Resting Electroencephalography Microstates and Alpha Power Modulation in Preschool-Aged Children with Autism Spectrum Disorder
Resting Electroencephalography Microstates and Alpha Power Modulation in Preschool-Aged Children with Autism Spectrum Disorder Open
Background/Objectives: Emerging evidence suggests that individuals with autism spectrum disorder (ASD) exhibit altered neural connectivity and disrupted brain network dynamics, which can be captured through EEG microstate analysis. Most re…
View article: Distinct effects of global signal regression on brain activity during propofol and sevoflurane anesthesia
Distinct effects of global signal regression on brain activity during propofol and sevoflurane anesthesia Open
Introduction Global signal regression (GSR) is widely used in functional magnetic resonance imaging (fMRI) analysis, yet its effects on anesthetic-related brain activity are not well understood. Methods Using fMRI data from patients under …
View article: Accurate Structure Prediction of Natural Products with NatGen
Accurate Structure Prediction of Natural Products with NatGen Open
Natural products (NPs), as a vital source of pharmaceutical agents, have contributed to the development of 60% of marketed small-molecule drugs. However, NP-based drug discovery faces a major challenge due to the combinatorial expansion of…
View article: An Evaluation Model for Brain Ischemia Protection in Mice by Low-Intensity Pulsed Ultrasound Stimulation Based on Functional Cortico-Muscular Coupling
An Evaluation Model for Brain Ischemia Protection in Mice by Low-Intensity Pulsed Ultrasound Stimulation Based on Functional Cortico-Muscular Coupling Open
(1) Background: Ischemic stroke is a major global public-health concern with complex pathogenesis. Current treatment strategies face challenges. Low-intensity pulsed ultrasound stimulation (LIPUS), a non-invasive neuromodulation technology…
View article: Terahertz radiation affects the dynamics of neurons by decreasing membrane area ratio
Terahertz radiation affects the dynamics of neurons by decreasing membrane area ratio Open
Terahertz radiation at specific frequencies and energies can mediate cellular morphology or function changes by exciting nonlinear resonance effects in proteins or DNA. However, the effects of terahertz radiation on neuronal morphology and…
View article: Enhancing Neural Synchrony with Endogenous-like 1/f Noise Stimulation
Enhancing Neural Synchrony with Endogenous-like 1/f Noise Stimulation Open
Aperiodic components of neural activity, characterized by endogenous 1/f noise dynamics, are hypothesized to support the emergence of large-scale cortical order and cognitive flexibility. Here, we combine computational modeling and human b…
View article: Transcriptomic Profiling Unveils <i>EDN3</i><sup>+</sup> Meningeal Fibroblasts as Key Players in Sturge‐Weber Syndrome Pathogenesis (Adv. Sci. 17/2025)
Transcriptomic Profiling Unveils <i>EDN3</i><sup>+</sup> Meningeal Fibroblasts as Key Players in Sturge‐Weber Syndrome Pathogenesis (Adv. Sci. 17/2025) Open
Sturge‐Weber Syndrome Meningeal fibroblasts contribute to the progression of leptomeningeal vascular malformation in Sturge‐Weber syndrome (SWS). In article number 2408888, Guoming Luan, Woo‐ping Ge, Yuguang Guan, and colleagues identify a…
View article: Functional brain network discrepancies in disorders of consciousness: A brain connectivity analysis
Functional brain network discrepancies in disorders of consciousness: A brain connectivity analysis Open
View article: Effect of Transcranial Light Stimulation on the Neurovascular Unit in the Human Brain
Effect of Transcranial Light Stimulation on the Neurovascular Unit in the Human Brain Open
Transcranial light stimulation (tLS) is emerging as a non-invasive approach for enhancing brain function and treating neurological disorders; however, its impact on the human neurovascular unit (NVU) remains poorly understood. Herein, we c…
View article: PTEN as a prognostic factor for radiotherapy plus immunotherapy response in nasopharyngeal carcinoma
PTEN as a prognostic factor for radiotherapy plus immunotherapy response in nasopharyngeal carcinoma Open
The findings suggest that PTEN could play a key role in enhancing the efficacy of NPC radiotherapy and immunotherapy. By shedding light on PTEN's impact on tumor growth and the immune microenvironment, this study lays the groundwork for fu…