Explanipedia

Potential Evaluation of Cross-Seasonal Heat Storage of Coal Mine Underground Reservoir: A Case Study Based on Multiphysics Coupling Numerical Simulation Method Open

Zhenyu Wang, Jiawei Tang, Zixu Hu, Qiang Guo, Haiqin Zhang , et al. · 2025

This study explores the innovative use of post-mining subsurface voids by proposing a coal mine goaf-based underground reservoir energy storage system. By fully utilizing the geothermal potential and insulation properties of the mined-out …

κ-carrageenan oligosaccharides alleviate MDP induced rumen epithelial cell inflammatory damage by inhibiting the activation of NOD2/NF-κB pathway Open

Yuhang Xiao, Xiaolin He, Jian Ma, Chunmei Du, Shangquan Gan , et al. · 2025

Introduction Under Subacute Ruminal Acidosis (SARA) conditions, harmful substances released by the massive lysis of ruminal bacteria are further degraded into small bacterial peptides, such as muramyl dipeptide (MDP). These degradation pro…

Growth Response of Submerged Macrophyte Vallisneria denseserrulata to Water Depth (Light Intensity) Changes Varies with Sediment Nutrient Level Open

Yudan Lin, Jinyang Yu, Haochi Zheng, Xiufeng Zhang, Yali Tang , et al. · 2025

The re-establishment of submerged macrophytes is crucial for the ecological restoration of eutrophic lakes. Water depth (light intensity) and sediment nutrient levels are key factors influencing the growth of these macrophytes. Although th…

A first-in-human study of quantitative ultrasound to assess transplant kidney fibrosis Open

Eno Hysi, Jihye Baek, Alexander Koven, Xiaolin He, Luisa Ulloa Severino , et al. · 2025

Health economics study of paliperidone palmitate in the treatment of schizophrenia: a 12-month cohort study Open

Xing Luo, Fang Liu, Jin Lü, Yuqi Cheng, Xiufeng Xu , et al. · 2024

The sesquiterpene lactone-enriched extract from Linderae Radix ameliorated high glucose-induced renal tubular epithelial injury via mediating PPARγ/Nrf2 pathway Open

Jian Hua, Hao Guan, Xue-Jian Li, Honghui Liao, Xiaolin He , et al. · 2024

Diabetic nephropathy (DN) is a common microvascular complication with limited effective interventions in diabetic patients. Linderae Radix is a traditional herbal tonic used to treat various kidney and metabolic diseases. In this study, we…

Health economics study of paliperidone palmitate in the treatment of schizophrenia: a 12-month cohort study Open

Xing Luo, Jicai Wang, Fang Liu, Jin Lü, Yuqi Cheng , et al. · 2024

Background To analyze the economic benefits of paliperidone palmitate in the treatment of schizophrenia. Methods We collected 546 patients who met the diagnostic criteria for schizophrenia according to the 《International Statistical Classi…

A gender specific risk assessment of coronary heart disease based on physical examination data Open

Hui Yang, Yamei Luo, Cai-Yi Ma, Tianyu Zhang, Tao Zhou , et al. · 2023

Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis Open

Xiaolin He, Monica F. Tolosa, Tianzhou Zhang, Santosh Kumar Goru, Luisa Ulloa Severino , et al. · 2022

Fibrotic diseases account for nearly half of all deaths in the developed world. Despite its importance, the pathogenesis of fibrosis remains poorly understood. Recently, the two mechanosensitive transcription cofactors YAP and TAZ have eme…

A Case Report of Imatinib-induced Acute Heart Failure and Literature Review Open

Zhaodong Li, Wen Qü, Xiaolin He, Xinhua Zhao, Yujun Luo , et al. · 2022

Patients with Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs) or acute lymphoblastic leukemia (ALL) are appropriate candidates for medical treatment using imatinib. Here, we re…

Effects of Lanthanum Modified Bentonite and Polyaluminium Chloride on the Environmental Variables in the Water and Sediment Phosphorus Form in Lake Yanglan, China Open

Ling Su, Zhong Chen, Lei Gan, Xiaolin He, Jinlei Yu , et al. · 2021

The application of lanthanum modified bentonite (Phoslock®) and polyaluminium chloride (PAC) is popular in the restoration of European temperate lakes; however, the effects of the application on the concentrations of phosphorus (P) in both…

Protective function of DJ-1/PARK7 in lipopolysaccharide and ventilator-induced acute lung injury Open

Hajera Amatullah, Tatiana Maron‐Gutierrez, Yuexin Shan, Sahil Gupta, James N. Tsoporis , et al. · 2020

Oxidative stress is considered one of the early underlying contributors of acute lung injury (ALI) and ventilator-induced lung injury (VILI). DJ-1, also known as PARK7, has a well-established role as an antioxidant. We have previously show…

Photoacoustic imaging of kidney fibrosis for assessing pretransplant organ quality Open

Eno Hysi, Xiaolin He, Muhannad N. Fadhel, Tianzhou Zhang, Adriana Krizova , et al. · 2020

Roughly 10% of the world's population has chronic kidney disease (CKD). In its advanced stages, CKD greatly increases the risk of hospitalization and death. Although kidney transplantation has revolutionized the care of advanced CKD, clini…

A new, easily generated mouse model of diabetic kidney fibrosis Open

Xiaolin He, Tianzhou Zhang, Monica F. Tolosa, Santosh Kumar Goru, Xiaolan Chen , et al. · 2019

RcPAL, a key gene in lignin biosynthesis in Ricinus communis L. Open

Jiannong Lu, Yuzhen Shi, Weijin Li, Sen Chen, Yafei Wang , et al. · 2019

Megalobrama amblycephala grazes preferentially on Hydrilla verticillata but makes more efficient use of Vallisneria denseserrulata: implications for biological control of submerged macrophytes Open

Chunyu Yin, Zhaoxia Wang, Yu Zhao, Yiming Gao, Wei Zhen , et al. · 2019

Growth of the meadow-forming macrophyte Vallisneria denseserrulata is often negatively impacted as result of shading by the canopy-forming Hydrilla verticillata . Grazing by the herbivorous cyprinid Megalobrama amblycephala is thought to c…

A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation Open

Marc A. Morgan, Ryan Rickels, Clayton K. Collings, Xiaolin He, Kaixiang Cao , et al. · 2017

Histone H3 Lys4 (H3K4) methylation is a chromatin feature enriched at gene cis -regulatory sequences such as promoters and enhancers. Here we identify an evolutionarily conserved factor, BRWD2/PHIP, which colocalizes with histone H3K4 meth…

Effect of miR-125b on dermal papilla cells of goat secondary hair follicle Open

Guangxian Zhou, Chao Yuan, Xiaolin He, Danju Kang, Xiao-Long Wang , et al. · 2016

Expression and Purification of Class 7 Semaphorin and Its PlexinC1 Receptor Using Baculovirus-Mediated Mammalian Cell Gene Transduction Open

Xiaohong Chen, Po‐Han Chen, Xiaolin He · 2016

YAP/TAZ Are Mechanoregulators of TGF-β-Smad Signaling and Renal Fibrogenesis Open

Stephen G. Szeto, Masahiro Narimatsu, Mingliang Lu, Xiaolin He, Ahmad Sidiqi , et al. · 2016

Like many organs, the kidney stiffens after injury, a process that is increasingly recognized as an important driver of fibrogenesis. Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are related mec…

Recombinant N–Terminal Slit2 Inhibits TGF-β–Induced Fibroblast Activation and Renal Fibrosis Open

Darren A. Yuen, Yiwei Huang, Guangying Liu, Sajedabanu Patel, Fei Fang , et al. · 2016

Fibrosis and inflammation are closely intertwined injury pathways present in nearly all forms of CKD for which few safe and effective therapies exist. Slit glycoproteins signaling through Roundabout (Robo) receptors have been described to …

Effect of calcium cyanamide, ammonium bicarbonate and lime mixture and ammonia water on survival of Ralstonia solanacearum and microbial community Open

Lijuan Liu, Chengliang Sun, Xingxing Liu, Xiaolin He, Miao Liu , et al. · 2016

Structure of Full-Length Human PDGFRβ Bound to Its Activating Ligand PDGF-B as Determined by Negative-Stain Electron Microscopy Open

Po‐Han Chen, Vinzenz M. Unger, Xiaolin He · 2015

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