Rennan Feng
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View article: Metabolomics study on dibenz[a,h]anthracene exposure-induced pulmonary injury in rats after intratracheal instillation
Metabolomics study on dibenz[a,h]anthracene exposure-induced pulmonary injury in rats after intratracheal instillation Open
Background Northern residents predominantly rely on coal-fired heating during winter, leading to severe air pollution. Polycyclic aromatic hydrocarbons (PAHs) adsorbed on atmospheric particulate matter pose significant health risks. Among …
View article: Association between dietary glycine intake and the prevalence of hypertension, hyperlipidemia, overweight or obesity in rural northern China: a cross-sectional study
Association between dietary glycine intake and the prevalence of hypertension, hyperlipidemia, overweight or obesity in rural northern China: a cross-sectional study Open
Objective The objective of this research is to investigate the relationship between dietary glycine consumption and the prevalence of hypertension, hyperlipidemia, and overweight or obesity in economically disadvantaged areas of northern C…
View article: Hospitalization of patients with nutritional anemia in the United States in 2020
Hospitalization of patients with nutritional anemia in the United States in 2020 Open
Background Nutritional anemia is highly prevalent and has triggered a globally recognized public health concern worldwide. Objective To better understand the prevalence of anemia and the state of nutritional health in developed countries t…
View article: The link between dietary nutrients intake and cardiovascular diseases in cold regions
The link between dietary nutrients intake and cardiovascular diseases in cold regions Open
Background The cold winter weather in northern China influences the dietary habits of its residents, contributing to a heightened risk of cardiovascular disorders, such as hypertension and coronary heart disease. Key factors include low ve…
View article: Breast-specific gamma imaging versus ultrasound and mammography for breast cancer diagnosis: A meta-analysis
Breast-specific gamma imaging versus ultrasound and mammography for breast cancer diagnosis: A meta-analysis Open
Breast-specific gamma imaging versus ultrasound and mammography for breast cancer diagnosis: A meta-analysis
View article: Ten Years of EWAS (Adv. Sci. 20/2021)
Ten Years of EWAS (Adv. Sci. 20/2021) Open
Epigenome‐Wide Association Study In article number 2100727 by Yongshuai Jiang, and co‐workers, the research process of Epigenome‐wide association study (EWAS), its application in biology and clinical translation are discussed. It concludes…
View article: Dietary isoflavones intake is inversely associated with non-alcoholic fatty liver disease, hyperlipidaemia and hypertension
Dietary isoflavones intake is inversely associated with non-alcoholic fatty liver disease, hyperlipidaemia and hypertension Open
This study investigated associations between total isoflavones and their categories (daidzein, genistein, glycitein) intake and the risks for metabolic disorders. We used the data of 6786 Chinese adults from the Nutrition Health Atlas Proj…
View article: Is Histidine promising in alleviating the risk of Metabolic disorder?
Is Histidine promising in alleviating the risk of Metabolic disorder? Open
Introduction In recent times, evidence from published reports; randomized clinical trial (RCT), human case-controls, metabolomics, animal and cell studies is gaining rapt significance on the ameliorative potential of histidine (His) in obe…
View article: Biomarker Identification of Maternal Genistein Exposure Induced Obesity by Metabonomics Analysis
Biomarker Identification of Maternal Genistein Exposure Induced Obesity by Metabonomics Analysis Open
The objective of this study was to confirm the effect of maternal genistein exposure on body weight of male offspring and the metabolic alterations associated with maternal genistein-induced obesity. Pregnant female Sprague-Dawley (SD) rat…
View article: Lean non‐alcoholic fatty liver disease patients had comparable total caloric, carbohydrate, protein, fat, iron, sleep duration and overtime work as obese non‐alcoholic fatty liver disease patients
Lean non‐alcoholic fatty liver disease patients had comparable total caloric, carbohydrate, protein, fat, iron, sleep duration and overtime work as obese non‐alcoholic fatty liver disease patients Open
Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is a multifactorial disease that involves a complex interaction between genetics, diet, and lifestyle. Although closely related with obese subjects, it is also common in lean hum…
View article: Free fatty acids profile among lean, overweight and obese non-alcoholic fatty liver disease patients: a case – control study
Free fatty acids profile among lean, overweight and obese non-alcoholic fatty liver disease patients: a case – control study Open
Our findings suggest 14:0 and 16:1 are promising for early diagnosis of NAFLD.
View article: Effects of Long-Term In Vivo Exposure to Di-2-Ethylhexylphthalate on Thyroid Hormones and the TSH/TSHR Signaling Pathways in Wistar Rats
Effects of Long-Term In Vivo Exposure to Di-2-Ethylhexylphthalate on Thyroid Hormones and the TSH/TSHR Signaling Pathways in Wistar Rats Open
Di-(2-ethylhexyl)phthalate (DEHP) was a widely used chemical with human toxicity. Recent in vivo and in vitro studies suggested that DEHP-exposure may be associated with altered serum thyroid hormones (THs) levels, but the underlying molec…
View article: Associations between Dietary Nutrient Intakes and Hepatic Lipid Contents in NAFLD Patients Quantified by 1H-MRS and Dual-Echo MRI
Associations between Dietary Nutrient Intakes and Hepatic Lipid Contents in NAFLD Patients Quantified by 1H-MRS and Dual-Echo MRI Open
Dietary habits are crucial in the progression of hepatic lipid accumulation and nonalcoholic fatty liver disease (NAFLD). However, there are limited studies using 1H-magnetic resonance spectroscopy (1H-MRS) and dual-echo in-phase and out-p…
View article: Relationships of Dietary Histidine and Obesity in Northern Chinese Adults, an Internet-Based Cross-Sectional Study
Relationships of Dietary Histidine and Obesity in Northern Chinese Adults, an Internet-Based Cross-Sectional Study Open
Our previous studies have demonstrated that histidine supplementation significantly ameliorates inflammation and oxidative stress in obese women and high-fat diet-induced obese rats. However, the effects of dietary histidine on general pop…
View article: Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition
Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition Open
The detrimental role of hepatic lipotoxicity has been well-implicated in the pathogenesis of NAFLD. Previously, we reported that inhibiting autophagy aggravated saturated fatty acid (SFA)-induced hepatotoxicity. Insulin, a physiological in…
View article: Interaction Effects between Organochlorine Pesticides and Isoflavones<i>In Vitro</i>and<i>In Vivo</i>
Interaction Effects between Organochlorine Pesticides and Isoflavones<i>In Vitro</i>and<i>In Vivo</i> Open
Organochlorine pesticides (OCPs) have caused increasing global concern due to their high toxicity, persistence, bioaccumulation, and significant adverse effects on human health. This study was to explore the interaction effects between OCP…
View article: The Ratio of Dietary Branched-Chain Amino Acids is Associated with a Lower Prevalence of Obesity in Young Northern Chinese Adults: An Internet-Based Cross-Sectional Study
The Ratio of Dietary Branched-Chain Amino Acids is Associated with a Lower Prevalence of Obesity in Young Northern Chinese Adults: An Internet-Based Cross-Sectional Study Open
This study aims to examine the association between the ratio of dietary branched chain amino acids (BCAA) and risk of obesity among young northern Chinese adults. A total of 948 randomly recruited participants were asked to finish our inte…
View article: Analyzing large-scale samples confirms the association between rs16892766 polymorphism and colorectal cancer susceptibility
Analyzing large-scale samples confirms the association between rs16892766 polymorphism and colorectal cancer susceptibility Open
Colorectal cancer (CRC) is a common complex disease caused by the combination of genetic variants and environmental factors. Genome-wide association studies (GWAS) have been performed and reported some novel CRC susceptibility variants. Th…