Xiaolin Shen
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View article: The effect of thyroid nodule location in ultrasound on the diagnosis of papillary thyroid carcinoma
The effect of thyroid nodule location in ultrasound on the diagnosis of papillary thyroid carcinoma Open
Thyroid isthmus nodule has a higher likelihood of malignancy. During the active surveillance process in low-risk papillary thyroid carcinoma patients, attention should be paid to the dynamic changing in the location of thyroid nodule.
View article: An expanded library of 76 integration sites for gene expression in <i>Saccharomyces cerevisiae</i>
An expanded library of 76 integration sites for gene expression in <i>Saccharomyces cerevisiae</i> Open
Constructing efficient yeast cell factories involves introducing heterologous biosynthetic pathways and overexpressing key genes. Chromosomal integration of recombinant genes is preferred over episomal plasmids for greater stability during…
View article: Evolution of supraglacial lakes over the pan-Antarctic ice sheet between 2014 and 2022: Assessment and the control factors
Evolution of supraglacial lakes over the pan-Antarctic ice sheet between 2014 and 2022: Assessment and the control factors Open
Widespread supraglacial lakes (SGLs) across the Antarctic surface can accelerate land ice flow and be linked to ice shelf disintegration, further affecting sea-level rise projections. However, previous studies usually focused on SGLs at re…
View article: MEMIT-Merge: Addressing MEMIT's Key-Value Conflicts in Same-Subject Batch Editing for LLMs
MEMIT-Merge: Addressing MEMIT's Key-Value Conflicts in Same-Subject Batch Editing for LLMs Open
As large language models continue to scale up, knowledge editing techniques that modify models' internal knowledge without full retraining have gained significant attention. MEMIT, a prominent batch editing algorithm, stands out for its ca…
View article: New taxa of Xylariales from Karst Ecosystems in Southwestern China
New taxa of Xylariales from Karst Ecosystems in Southwestern China Open
The order Xylariales consists of fungi that are widely distributed and commonly found on decaying wood, fallen branches, and trunks. Despite the taxonomic and morphological challenges in accurately identifying species within this group, in…
View article: Biodegradation: the best solution to the world problem of discarded polymers
Biodegradation: the best solution to the world problem of discarded polymers Open
The widespread use of polymers has made our lives increasingly convenient by offering a more convenient and dependable material. However, the challenge of efficiently decomposing these materials has resulted in a surge of polymer waste, po…
View article: Microbial synthesis of gallic acid and its glucoside β‐glucogallin
Microbial synthesis of gallic acid and its glucoside β‐glucogallin Open
Gallic acid (GA) and β‐glucogallin (BGG) are natural products with diverse uses in pharmaceutical, food, chemical and cosmetic industries. They are valued for their wide‐ranging properties such as antioxidant, antibacterial, antidiabetic, …
View article: Hydroxytyrosol-1-Glucopyranoside Alleviates Senescence via Nrf2 and AMPK Signaling Pathway
Hydroxytyrosol-1-Glucopyranoside Alleviates Senescence via Nrf2 and AMPK Signaling Pathway Open
Hydroxytyrosol-1-glucopyranoside (HTG) is a natural phenylethanol glycoside with promising antiaging properties.In this study, we developed a biotransformation and purification process to effectively prepare high-purity HTG.We constructed …
View article: Selenium-Chelating Peptide Derived from Wheat Gluten: In Vitro Functional Properties
Selenium-Chelating Peptide Derived from Wheat Gluten: In Vitro Functional Properties Open
The efficacy of selenium-chelating polypeptides derived from wheat protein hydrolysate (WPH-Se) includes enhancing antioxidant capacity, increasing bioavailability, promoting nutrient absorption, and improving overall health. This study ai…
View article: Exploring the role of flavin-dependent monooxygenases in the biosynthesis of aromatic compounds
Exploring the role of flavin-dependent monooxygenases in the biosynthesis of aromatic compounds Open
Hydroxylated aromatic compounds exhibit exceptional biological activities. In the biosynthesis of these compounds, three types of hydroxylases are commonly employed: cytochrome P450 (CYP450), pterin-dependent monooxygenase (PDM), and flavi…
View article: Preparation, structural characterization and functional properties of a novel selenium chelating peptide derived from the hydrolyzate of wheat protein
Preparation, structural characterization and functional properties of a novel selenium chelating peptide derived from the hydrolyzate of wheat protein Open
Organic selenium has been widely studied for its ability to better fulfill the physiological functions of selenium. In this study, a novel organic selenium (wheat protein hydrolyzate chelated selenium, WPH-Se) was prepared by chelating the…
View article: Rational protein engineering of a ketoacids decarboxylase for efficient production of 1,2,4-butanetriol from arabinose
Rational protein engineering of a ketoacids decarboxylase for efficient production of 1,2,4-butanetriol from arabinose Open
Background Lignocellulose, the most abundant non-edible feedstock on Earth, holds substantial potential for eco-friendly chemicals, fuels, and pharmaceuticals production. Glucose, xylose, and arabinose are primary components in lignocellul…
View article: Breast cancer-related lymphedema and recurrence of breast cancer: Protocol for a prospective cohort study in China
Breast cancer-related lymphedema and recurrence of breast cancer: Protocol for a prospective cohort study in China Open
Introduction The primary aim is to determine the factors associated with breast cancer-related lymphedema and to identify new associated factors for the recurrence of breast cancer and depression. The secondary objective is to investigate …
View article: Effects of tillage management on cbbL-carrying bacteria and soil organic carbon dynamics across aggregate size classes in the farmland of North China Plain
Effects of tillage management on cbbL-carrying bacteria and soil organic carbon dynamics across aggregate size classes in the farmland of North China Plain Open
Calvin-Benson-Bassham cycle (cbbL)-carrying bacteria in soil are essential to renew and circulate organic matter. However, the relation between cbbL-carrying bacteria and soil carbon dynamics under tillage managements, especially across th…
View article: Establishing biosynthetic pathway for the production of p-hydroxyacetophenone and its glucoside in Escherichia coli
Establishing biosynthetic pathway for the production of p-hydroxyacetophenone and its glucoside in Escherichia coli Open
p-Hydroxyacetophenone (p-HAP) and its glucoside picein are plant-derived natural products that have been extensively used in chemical, pharmaceutical and cosmetic industries owing to their antioxidant, antibacterial and antiseptic activiti…
View article: Changes of Ca forms and chelate-soluble pectin in cherry tomatoes treated with ultrasound and calcium lactate
Changes of Ca forms and chelate-soluble pectin in cherry tomatoes treated with ultrasound and calcium lactate Open
The physicochemical properties, polygalacturonase and pectin methylesterase activity, calcium form, and structure of chelate-soluble pectin (CSP) in cherry tomatoes were studied. The total calcium and CSP contents for calcium with ultrasou…
View article: A survey of systemic lupus erythematosus patients' attitudes toward influenza and pneumococcal vaccination in Southwest China
A survey of systemic lupus erythematosus patients' attitudes toward influenza and pneumococcal vaccination in Southwest China Open
Introduction Vaccination is the most effective measure for prevention against infectious diseases in patients with systemic lupus erythematosus (SLE). Therefore, it is important to know SLE patients' attitudes toward influenza and pneumoco…
View article: Coculture engineering for efficient production of vanillyl alcohol in Escherichia coli
Coculture engineering for efficient production of vanillyl alcohol in Escherichia coli Open
Vanillyl alcohol is a precursor of vanillin, which is one of the most widely used flavor compounds. Currently, vanillyl alcohol biosynthesis still encounters the problem of low efficiency. In this study, coculture engineering was adopted t…
View article: Synergistic utilization of carbon sources for efficient biosynthesis of N-acetylglucosamine
Synergistic utilization of carbon sources for efficient biosynthesis of N-acetylglucosamine Open
N-acetylglucosamine (GlcNAc) is an amino monosaccharide that has a variety of bioactivities and is widely used in pharmaceutical and food industries. Production of GlcNAc by chitin hydrolysis is limited by the supply of raw materials and e…
View article: Insights of microorganisms role in rice and rapeseed wastes as potential sorbents for metal removal
Insights of microorganisms role in rice and rapeseed wastes as potential sorbents for metal removal Open
Rice and rapeseed agricultural wastes, as nonliving biomass, are proposed for heavy metal remediation in polluted effluents (chromium, cadmium, copper and lead). The physicochemical characterization of these biomasses shows that the surfac…
View article: IOU-Guided Siamese Tracking
IOU-Guided Siamese Tracking Open
Target tracking is currently a hot research topic in machine vision. The traditional target tracking algorithm based on the generative model selects target features manually, which has a simple structure and fast running speed, but it cann…