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View article: Comparison of sarcopenia prevalence and prognostic features between HFrEF and HFpEF: a systematic review and meta-analysis
Comparison of sarcopenia prevalence and prognostic features between HFrEF and HFpEF: a systematic review and meta-analysis Open
Background Sarcopenia is closely associated with heart failure (HF); however, no prior meta-analysis has specifically addressed its relation with different ejection fraction phenotypes. This study investigated the prevalence of sarcopenia …
View article: A comprehensive analysis of magnetic resonance imaging and laboratory features in pyogenic, tuberculous, brucellar, and fungal spondylitis
A comprehensive analysis of magnetic resonance imaging and laboratory features in pyogenic, tuberculous, brucellar, and fungal spondylitis Open
A predictive model integrating imaging and clinical features effectively differentiates the four major types of infectious spondylitis, enhancing diagnostic accuracy. The online application extends the practical utility of our findings.
View article: Effects of imperatorin on chronic periodontitis associated with type 2 diabetes mellitus
Effects of imperatorin on chronic periodontitis associated with type 2 diabetes mellitus Open
Imperatorin demonstrates anti-inflammatory properties for alleviating periodontitis in type 2 diabetes while promoting alveolar bone regeneration; the underlying molecular mechanism may be associated with the downregulation of P2Y1 recepto…
View article: Mechanistic insights into non-negligible toxicity evolution of microplastics under different aging processes
Mechanistic insights into non-negligible toxicity evolution of microplastics under different aging processes Open
Aging processes affect the physiochemical properties, environmental behavior and ecological risk of MPs (microplastics). In this review, the toxic evolution of MPs under different aging processes and their leachate on organisms are summari…
View article: Conventional net tow versus environmental DNA for metabarcoding-based analysis of plankton-environment interactions in polluted aquatic ecosystems
Conventional net tow versus environmental DNA for metabarcoding-based analysis of plankton-environment interactions in polluted aquatic ecosystems Open
Human societal development has caused rapid degradation of freshwater ecosystems, resulting in significant biodiversity decline globally. The conservation of aquatic ecosystems, particularly the management of biodiversity in urban areas, h…
View article: Usnea improves high-fat diet- and vitamin D3-induced atherosclerosis in rats by remodeling intestinal flora homeostasis
Usnea improves high-fat diet- and vitamin D3-induced atherosclerosis in rats by remodeling intestinal flora homeostasis Open
Background: Usnea has various pharmacological properties, including anti-inflammatory, antitumor, antioxidant, antiviral, and cardiovasculoprotective effects. Aim of the study: To investigate the potential mechanisms underlying the anti-at…
View article: Differential Response of Ileal and Colonic Microbiota in Rats with High-Fat Diet-Induced Atherosclerosis
Differential Response of Ileal and Colonic Microbiota in Rats with High-Fat Diet-Induced Atherosclerosis Open
Growing evidence suggests that gut microbiota are associated with atherosclerosis (AS). However, the functional heterogeneity of each gut segment gives rise to regional differences in gut microbiota. We established a rat model of AS by fee…
View article: Personalized mid-course FDG-PET based adaptive treatment planning for non-small cell lung cancer using machine learning and optimization
Personalized mid-course FDG-PET based adaptive treatment planning for non-small cell lung cancer using machine learning and optimization Open
Objective . Traditional radiotherapy (RT) treatment planning of non-small cell lung cancer (NSCLC) relies on population-wide estimates of organ tolerance to minimize excess toxicity. The goal of this study is to develop a personalized trea…
View article: Marked Response of Rat Ileal and Colonic Microbiota After the Establishment of Alzheimer’s Disease Model With Bilateral Intraventricular Injection of Aβ (1-42)
Marked Response of Rat Ileal and Colonic Microbiota After the Establishment of Alzheimer’s Disease Model With Bilateral Intraventricular Injection of Aβ (1-42) Open
Alzheimer’s disease (AD) is a common neurodegenerative disease. More evidence has shown that gut microbiota is closely associated with AD. Also, studies have shown that the distribution of gut microbiota vary in different sections of the i…
View article: Rethinking the Transport Infrastructure-Led Development Model
Rethinking the Transport Infrastructure-Led Development Model Open
Transport infrastructure-led development has been well recognized, especially in regard to China’s achievement, which has led to a growing range of programs and initiatives. However, some failures have subsequently raised debates over the …
View article: The role of Ca<sup>2+</sup>/Calcineurin/NFAT signalling pathway in osteoblastogenesis
The role of Ca<sup>2+</sup>/Calcineurin/NFAT signalling pathway in osteoblastogenesis Open
The bone remodelling process is closely related to bone health. Osteoblasts and osteoclasts participate in the bone remodelling process under the regulation of various factors inside and outside. Excessive activation of osteoclasts or lack…
View article: Research on Web Robot Detection Technology for Concept Drift
Research on Web Robot Detection Technology for Concept Drift Open
Web robots have long been significant participants of the internet and the detection is deemed to be essential. Contemporary web robot detection techniques lack the ability to detect when the characteristics of web robots drastically chang…
View article: Antidepressant effects of total iridoids of <i>Valeriana jatamansi</i> via the intestinal flora-blood–brain barrier pathway
Antidepressant effects of total iridoids of <i>Valeriana jatamansi</i> via the intestinal flora-blood–brain barrier pathway Open
TIV may modulate the intestinal flora, thereby inducing the expression of ZO-1 and occludin, protecting the BBB and exerting an antidepressant effect.
View article: Clinical characteristics and viral shedding kinetics of 38 asymptomatic patients with coronavirus disease 2019
Clinical characteristics and viral shedding kinetics of 38 asymptomatic patients with coronavirus disease 2019 Open
This study aims to investigate the clinical characteristics and viral shedding kinetics of asymptomatic patients with coronavirus disease 2019 (COVID-19). The data of 38 asymptomatic patients positive for SARS-CoV-2 nucleic acid were colle…
View article: Numerical simulation study on the mechanical behavior of shale core and reservoir rock mass
Numerical simulation study on the mechanical behavior of shale core and reservoir rock mass Open
After the hydraulic fracturing of the shale reservoir, the stress field changes during the mining process. The stress sensitivity of the reservoir affects its development capabilities. Moreover, the stress sensitivity of shale reservoirs o…