Xiaoman Wei
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View article: Resurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong
Resurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong Open
Hong Kong experienced a surge of Omicron BA.2 infections in early 2022, resulting in one of the highest per-capita death rates of COVID-19. The outbreak occurred in a dense population with low immunity towards natural SARS-CoV-2 infection,…
View article: The episodic resurgence of highly pathogenic avian influenza H5 virus
The episodic resurgence of highly pathogenic avian influenza H5 virus Open
Highly pathogenic avian influenza (HPAI) H5N1 activity has intensified globally since 2021, replacing the dominant clade 2.3.4.4 H5N8 virus. H5N1 viruses have spread rapidly to four continents, causing increasing reports of mass mortality …
View article: Detection of Clade 2.3.4.4b Avian Influenza A(H5N8) Virus in Cambodia, 2021
Detection of Clade 2.3.4.4b Avian Influenza A(H5N8) Virus in Cambodia, 2021 Open
In late 2021, highly pathogenic avian influenza A(H5N8) clade 2.3.4.4b viruses were detected in domestic ducks in poultry markets in Cambodia. Surveillance, biosafety, and biosecurity efforts should be bolstered along the poultry value cha…
View article: The episodic resurgence of highly pathogenic avian influenza H5 virus
The episodic resurgence of highly pathogenic avian influenza H5 virus Open
Highly pathogenic avian influenza (HPAI) H5N1 activity has intensified globally since 2021, replacing the dominant clade 2.3.4.4 H5N8 virus. H5N1 viruses have spread rapidly to four continents, causing increasing reports of mass mortality …
View article: Resurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong
Resurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong Open
After keeping infections at bay for two years, Hong Kong experienced a surge of Omicron BA.2 infections in early 2022 that overwhelmed the health care system, isolation facilities, and contact tracing capacity, leading to one of the highes…
View article: Genomic epidemiology of seasonal influenza circulation in China during prolonged border closure from 2020 to 2021
Genomic epidemiology of seasonal influenza circulation in China during prolonged border closure from 2020 to 2021 Open
China experienced a resurgence of seasonal influenza activity throughout 2021 despite intermittent control measures and prolonged international border closure. We show genomic evidence for multiple A(H3N2), A(H1N1), and B/Victoria transmis…
View article: Genomic epidemiology of influenza B circulation in China during prolonged border closure from 2020 to 2021
Genomic epidemiology of influenza B circulation in China during prolonged border closure from 2020 to 2021 Open
China experienced a resurgence of seasonal influenza activity throughout 2021 under intermittent control measures and prolonged international border closure. We show genomic evidence for multiple A(H3N2), A(H1N1), and B/Victoria transmissi…
View article: Multiple Infiltration and Cross-Species Transmission of Foamy Viruses across the Paleozoic to the Cenozoic Era
Multiple Infiltration and Cross-Species Transmission of Foamy Viruses across the Paleozoic to the Cenozoic Era Open
Foamy viruses (FVs) represent, more so than other viruses, the best model of coevolution between a virus and a host. This study represents the largest investigation so far of amphibian FVs and reveals 412 FVs of 6 distinct lineages from th…
View article: Viromes in Marine Ecosystems Reveal Remarkable Invertebrate RNA Virus Diversity
Viromes in Marine Ecosystems Reveal Remarkable Invertebrate RNA Virus Diversity Open
Ocean viromes remain poorly understood and little is known about the ecological factors driving aquatic RNA virus evolution. In this study, we used a meta-transcriptomic approach to characterize the viromes of 58 marine invertebrate specie…
View article: Multiple infiltration and cross-species transmission of foamy viruses across Paleozoic to Cenozoic era
Multiple infiltration and cross-species transmission of foamy viruses across Paleozoic to Cenozoic era Open
Foamy viruses (FVs) are complex retroviruses that can infect humans and other animals. In this study, by integrating transcriptomic and genomic data, we discovered 412 FVs from 6 lineages in amphibians, which significantly increased the kn…
View article: Co-circulation of multiple reassortant H6 subtype avian influenza viruses in wild birds in eastern China, 2016–2017
Co-circulation of multiple reassortant H6 subtype avian influenza viruses in wild birds in eastern China, 2016–2017 Open
Background H6 subtype influenza viruses were prevalent in domestic poultry and wild birds, which also could pose potential threat to humans. However, little is known about the prevalence of H6 subtype viruses in wild birds in eastern China…
View article: Effects of Probiotics as Antibiotics Substitutes on Growth Performance, Serum Biochemical Parameters, Intestinal Morphology, and Barrier Function of Broilers
Effects of Probiotics as Antibiotics Substitutes on Growth Performance, Serum Biochemical Parameters, Intestinal Morphology, and Barrier Function of Broilers Open
The aim of this study was to investigate the effects of the combination of probiotics replacing antibiotics on growth performance, serum biochemical parameters, intestinal morphology, and expression of tight junction proteins in intestinal…
View article: Identification and evolution of avian endogenous foamy viruses
Identification and evolution of avian endogenous foamy viruses Open
A history of long-term co-divergence means that foamy viruses (family Retroviridae ) provide an ideal framework to understanding virus-host evolution over extended time periods. Endogenous foamy viruses (EndFVs) are rare, and to date have …
Identification and evolution of avian endogenous foamy viruses Open
A history of long-term co-divergence means that foamy viruses (family Retroviridae) provide an ideal framework to understanding virus-host evolution over extended time periods. Endogenous foamy viruses (EndFVs) are rare, and to date have o…
View article: A reptilian endogenous foamy virus sheds light on the early evolution of retroviruses
A reptilian endogenous foamy virus sheds light on the early evolution of retroviruses Open
Endogenous retroviruses (ERVs) represent host genomic ‘fossils’ of ancient viruses. Foamy viruses, including those that form endogenous copies, provide strong evidence for virus-host co-divergence across the vertebrate phylogeny. Endogenou…
View article: A Reptilian Endogenous Foamy Virus Sheds Light on the Early Evolution of Retroviruses
A Reptilian Endogenous Foamy Virus Sheds Light on the Early Evolution of Retroviruses Open
Endogenous retroviruses (ERVs) can be thought of as host genomic fossils of ancient viruses. Foamy viruses, including those that form endogenous copies, provide strong evidence for virus-host co-divergence across the vertebrate phylogeny. …
View article: Genetic Analysis of Reemerging GII.P16-GII.2 Noroviruses in 2016–2017 in China
Genetic Analysis of Reemerging GII.P16-GII.2 Noroviruses in 2016–2017 in China Open
Our findings provide new insights into GII.2 norovirus epidemics and highlight the necessity of enhanced global surveillance for potential epidemics of rare-genotype noroviruses.
View article: Sudden emergence of human infections with H7N9 avian influenza A virus in Hubei province, central China
Sudden emergence of human infections with H7N9 avian influenza A virus in Hubei province, central China Open
There have been five waves of H7N9 avian influenza virus (AIV) infection in humans since its initial emergence in China in 2013, posing a significant threat to public health. Hubei province was free local transmission during the first four…
View article: Emergence and Adaptation of a Novel Highly Pathogenic H7N9 Influenza Virus in Birds and Humans from a 2013 Human-Infecting Low-Pathogenic Ancestor
Emergence and Adaptation of a Novel Highly Pathogenic H7N9 Influenza Virus in Birds and Humans from a 2013 Human-Infecting Low-Pathogenic Ancestor Open
Since its emergence in 2013, the H7N9 low-pathogenic avian influenza virus (LPAIV) has been circulating in domestic poultry in China, causing five waves of human infections. A novel H7N9 highly pathogenic avian influenza virus (HPAIV) vari…