Xiaona Wang
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View article: Application of an artificial intelligence-based airway identification system in tracheal intubation
Application of an artificial intelligence-based airway identification system in tracheal intubation Open
The YOLO model can effectively recognize and label airway anatomical structures, serving as a reliable tool to guide operators in real time to complete tracheal intubation. Its deployment on mobile devices emphasizes its clinical practical…
View article: CCDC 2476440: Experimental Crystal Structure Determination
CCDC 2476440: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Studies on the single-chain antibody (CRAb20) effectively protects chickens against very virulent infectious bursal disease virus
Studies on the single-chain antibody (CRAb20) effectively protects chickens against very virulent infectious bursal disease virus Open
Infectious Bursal Disease Virus (IBDV) infection leads to the destruction of B lymphocytes in chicks, resulting in severe immunosuppression. In recent years, the prevalence of very virulent IBDV (vvIBDV) have significantly increased the co…
View article: Biogeochemical dynamics of dissolved organic matter in the Changjiang Estuary during a late flooding season
Biogeochemical dynamics of dissolved organic matter in the Changjiang Estuary during a late flooding season Open
To address the knowledge gap concerning the behavioral dynamics of dissolved organic matter (DOM) in the Changjiang Estuary during the late flooding season, we conducted an extensive sampling campaign during which 188 water samples were sy…
View article: Intercellular transfer of SerpinE2 activates PI3K-AKT and β-catenin signaling to promote cardiac hypertrophy
Intercellular transfer of SerpinE2 activates PI3K-AKT and β-catenin signaling to promote cardiac hypertrophy Open
Background Effective inhibition of pathological cardiac hypertrophy is critical for managing various cardiovascular diseases, especially in cold environments. The communication between cardiomyocytes and fibroblasts, mediated by secreted p…
View article: Multi-omics profiling reveals single-seed mutants of Ephedra saxatilis as dominant variants in high-altitude Xizang
Multi-omics profiling reveals single-seed mutants of Ephedra saxatilis as dominant variants in high-altitude Xizang Open
Ephedra species, important Tibetan medicinal plants, are widely distributed across the Qinghai-Tibet Plateau at altitudes of 2700–5000 m. Their adaptation to high-altitude environments, such as low temperatures, strong UV radiation and low…
View article: Identification of three novel GNAO1 variants in a Chinese cohort with GNAO1 encephalopathy: expanding the clinical and genetic spectrum
Identification of three novel GNAO1 variants in a Chinese cohort with GNAO1 encephalopathy: expanding the clinical and genetic spectrum Open
Objective To summarize the clinical characteristics of a cohort of nine Chinese children with GNAO1 encephalopathy and analyze their genotypes. Methods A retrospective study was conducted on nine children diagnosed with GNAO1 encephalopath…
View article: [LncRNA SNHG15 promotes proliferation, migration and invasion of lung adenocarcinoma cells by regulating COX6B1 through sponge adsorption of miR-30b-3p].
[LncRNA SNHG15 promotes proliferation, migration and invasion of lung adenocarcinoma cells by regulating COX6B1 through sponge adsorption of miR-30b-3p]. Open
LncRNA SNHG15 may compete with COX6B1 to bind miR-30b-3p through a ceRNA mechanism to affect proliferation, migration, and invasion of lung adenocarcinoma cells.
View article: Deficiency of calretinin in prefrontal cortex causes behavioral deficits relevant to autism spectrum disorder in mice
Deficiency of calretinin in prefrontal cortex causes behavioral deficits relevant to autism spectrum disorder in mice Open
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by core symptoms including deficits in social interaction, repetitive and stereotyped behaviors, along with higher levels of anxiety and cognitive impairments. P…
View article: Conversion therapy with sintilimab combined with chemotherapy and apatinib in stage <scp>IV</scp> gastric cancer
Conversion therapy with sintilimab combined with chemotherapy and apatinib in stage <span>IV</span> gastric cancer Open
In selected patients with stage IV gastric cancer, radical surgery after conversion therapy may increase survival benefit; however, there is currently no standard protocol for conversion therapy. We explored the feasibility and efficacy of…
View article: Fertility intention of college students responding to the three-child policy in Guangzhou, China: a cross-sectional study
Fertility intention of college students responding to the three-child policy in Guangzhou, China: a cross-sectional study Open
Background In recent decades, a noticeable decline in birth rates has been observed globally, particularly in developing countries. Aganist this backdrop, this study investigates fertility intentions and associated factors among college st…
View article: Quaternary sediment thicknesses, paleochannels and hazard assessment revealed by a dense array in the Guangdong-Hong Kong-Macao Greater Bay Area
Quaternary sediment thicknesses, paleochannels and hazard assessment revealed by a dense array in the Guangdong-Hong Kong-Macao Greater Bay Area Open
The Guangdong-Hong Kong-Macao Greater Bay Area (GBA), a densely populated region, plays a vital role in the economic development of East Asia. The accurate thickness of near-surface loose sediment layers plays an important role in the cons…
View article: Activation of autophagy is required for clearance of mitochondrial ROS in patients with asthenozoospermia
Activation of autophagy is required for clearance of mitochondrial ROS in patients with asthenozoospermia Open
Autophagy is regarded as an essential process for maintaining cell homeostasis. However, its role in the regulation of sperm motility is still less understood. In this study, we found that mitochondrial oxidative species (mROS) levels were…
View article: <i>Pulsatilla saponin D</i> inhibits invasion and metastasis of triple-negative breast cancer cells through multiple targets and pathways.
<i>Pulsatilla saponin D</i> inhibits invasion and metastasis of triple-negative breast cancer cells through multiple targets and pathways. Open
The inhibitory effects of PSD on TNBC invasion and metastasis are mediated by multiple targets and pathways.
View article: Antondine Injection-Associated Fixed Drug Eruption: A Case Report
Antondine Injection-Associated Fixed Drug Eruption: A Case Report Open
Background: Fixed drug eruption (FDE) is a drug hypersensitivity reaction caused by antibiotics and non-steroidal anti-inflammatory drugs primarily. Antondine injection is a drug used to reduce fever, mainly composed of aminopyrine, antipy…
View article: Apolipoprotein B/Apolipoprotein A1 ratio is an independent prognostic factor in pancreatic cancer
Apolipoprotein B/Apolipoprotein A1 ratio is an independent prognostic factor in pancreatic cancer Open
ApoB/ApoA1 might be an independent prognostic factor of pancreatic cancer.
View article: Dietary Selenium Intake and All-Cause Mortality in Diabetic Kidney Disease: A Dose-Response Relationship
Dietary Selenium Intake and All-Cause Mortality in Diabetic Kidney Disease: A Dose-Response Relationship Open
OBJECTIVE Selenium plays a complex role in human health as an essential nutrient. Basic research has shown that selenium has antioxidant and anti-inflammatory effects. At present, the relationship between dietary selenium intake and mortal…
View article: Case report: Second report of neuromuscular syndrome caused by biallelic variants in ASCC3
Case report: Second report of neuromuscular syndrome caused by biallelic variants in ASCC3 Open
Introduction Activating Signal Cointegrator 1 Complex, Subunit 3 ( ASCC3 ) has been implicated in the pathogenesis of neurodevelopmental disorders and neuromuscular diseases (MIM: 620700). This paper analyzes the clinical manifestations of…
View article: Does the guide sheath outperform the non-guide sheath method in endobronchial ultrasound-guided biopsy of peripheral pulmonary lesions?—a meta-analysis
Does the guide sheath outperform the non-guide sheath method in endobronchial ultrasound-guided biopsy of peripheral pulmonary lesions?—a meta-analysis Open
EBUS-GS and EBUS-nGS showed no significant difference in the overall diagnostic rate for PPLs. When using a bronchoscope with an outer diameter of 3.0 mm or a channel diameter of 1.7 mm, or when lesions are ≤30 mm or located in the lower l…
View article: Noninvasive neurostimulation promotes working memory performance in older adults: a systematic review
Noninvasive neurostimulation promotes working memory performance in older adults: a systematic review Open
Working memory is a core component of high-level cognitive functions. A key feature of cognitive decline in older adults is the impairment of working memory capacity, which is also observed in many clinical conditions. In recent years, non…
View article: Sonography and Transthoracic Echocardiography for Diagnosis of Systemic Cardiovascular Metastatic Tumor Thrombi
Sonography and Transthoracic Echocardiography for Diagnosis of Systemic Cardiovascular Metastatic Tumor Thrombi Open
Sonography and transthoracic echocardiography (TTE) are seldom used for assessment of metastatic tumor thrombi in the cardiovascular system in routine clinical practice. We performed this retrospective study to evaluate the combination of …
View article: Research Progress of Optical Satellite Remote Sensing Monitoring Asphalt Pavement Aging
Research Progress of Optical Satellite Remote Sensing Monitoring Asphalt Pavement Aging Open
The aging condition of asphalt pavement is an invaluable basis for traffic infrastructure evaluation. Due to the amount of time and high cost of monitoring and identifying asphalt pavement aging, many current studies focus on satellite rem…
View article: An integrated bioinformatics analysis to identify the shared biomarkers in patients with obstructive sleep apnea syndrome and nonalcoholic fatty liver disease
An integrated bioinformatics analysis to identify the shared biomarkers in patients with obstructive sleep apnea syndrome and nonalcoholic fatty liver disease Open
Background Obstructive sleep apnea (OSA) syndrome and nonalcoholic fatty liver disease (NAFLD) have been shown to have a close association in previous studies, but their pathogeneses are unclear. This study explores the molecular mechanism…