Explanipedia

Exploring the link between diet quality and testosterone deficiency: evidence from NHANES 2011–2016 Open

Xianlin Zhan, Wei Yan, Fei Xu, Jing Liu, Quan Zhao · 2025

Better adherence to diet quality indices, as measured by HEI-2020 and CDAI, is associated with a lower risk of TD.

Predictive Value of Hepatitis B Core-Related Antigen for Multiple Recurrence Outcomes After Treatment Cessation in Chronic Hepatitis B: A Meta-Analysis Study Open

Guanghua Yu, Meiqi Cheng, Yuxin Duan, Myoung-Ah Kang, Ning Jiang , et al. · 2025

Background: Hepatitis B core-related antigen (HBcrAg), a novel serum biomarker reflecting the activity of intrahepatic covalently closed circular DNA (cccDNA), has generated conflicting evidence regarding its clinical utility for predictin…

Pro-repair macrophages driven by CGRP rescue white matter integrity following intracerebral hemorrhage Open

Huaping Huang, Yirui Kuang, Yang Chen, Yi Zhang, Jiayin Zhou , et al. · 2025

Therapeutic mechanisms of Acorus tatarinowii and its bioactive compounds in cardiovascular diseases: A comprehensive review Open

Yuting Qiu, Peng Zhao, Xu Lin, Jun Zeng, Ding Wen Wu , et al. · 2025

This review highlights A. tatarinowii and its bioactive components as innovative candidates for CVD management. The incorporation of nanotechnology represents a transformative strategy to optimize their pharmacological effects. Future rese…

Correction: Cardiovascular diseases and depression: A meta-analysis and Mendelian randomization analysis Open

Jun Zeng, Yuting Qiu, Chengying Yang, Xinrong Fan, Xiangyu Zhou , et al. · 2025

Causal relationship between molecular markers of biological aging and orthopedic diseases: A two-sample bidirectional Mendelian randomization study Open

Wei Yan, Yichen Zhao, Jiahui Zhang, Ping Jiang, Honghong Ma , et al. · 2025

Cardiovascular diseases and depression: A meta-analysis and Mendelian randomization analysis Open

Jun Zeng, Yuting Qiu, Chengying Yang, Xinrong Fan, Xiangyu Zhou , et al. · 2025

Depression is a common psychiatric symptom among patients with cardiovascular disease (CVD), adversely affecting their health. Despite the identification of various contributing factors, the precise mechanisms linking CVD and depression re…

Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens Open

Zhe Hu, Hui Ai, Zhen Wang, Shuping Huang, Honglei Sun , et al. · 2025

H9N2 avian influenza virus (AIV) is endemic in poultry worldwide and increasingly zoonotic. Despite the long-term widespread use of inactivated vaccines, H9N2 AIVs remain dominant in chicken flocks. We demonstrated that inactivated vaccine…

Inversion Method of Lightning Current Distribution on a Surface Conductor Represented by Thin Lines Open

Zemin Duan, Tong Chen, Yeyuan Huang, Xinping Li, Shanliang Qiu , et al. · 2025

Electromagnetic simulation and pre-analysis of electromagnetic compatibility for lightning effects are important. It is difficult to estimate the surface current of surface structures represented by thin lines. In this study, we simplified…

eLife Assessment: Characterisation and comparison of semen microbiota and bacterial load in men with infertility, recurrent miscarriage, or proven fertility Open

Wei Yan · 2025

Frailty as a mediator between sleep quality and cognitive impairment among the rural older adults: a cross-sectional study Open

Ping Dong, Cheng Cheng, Wenqiang Yin, Ziyuan Li, Y T Shi , et al. · 2025

The deep learning radiomics nomogram helps to evaluate the lymph node status in cervical adenocarcinoma/adenosquamous carcinoma Open

Mei Xiao, Le Fu, Ting Qian, Wei Yan, Hua Feng , et al. · 2024

Objectives The accurate assessment of lymph node metastasis (LNM) can facilitate clinical decision-making on radiotherapy or radical hysterectomy (RH) in cervical adenocarcinoma (AC)/adenosquamous carcinoma (ASC). This study aims to develo…

eLife Assessment: Characterisation and comparison of semen microbiota and bacterial load in men with infertility, recurrent miscarriage, or proven fertility Open

Wei Yan · 2024

Overexpression of Cassava MeSTP7 Promotes Arabidopsis Seedling Development Open

Sha Geng, Xiaotong Wang, Wei Yan, Qian Liu, Na Wang , et al. · 2024

The sugar transporter (STP) gene family is a key regulator of plant development, which is crucial for the efficient transport and utilization of sugars during plant growth and development. In this study, we identified the MeSTP7 gene, whic…

Emerging role of gut microbiota extracellular vesicle in neurodegenerative disorders and insights on their therapeutic management Open

Adil Hassan, Yin Huang, Mahjabina, Otmilda Hapsari Sudiro, Xiangxiu Wang , et al. · 2024

Targeting gut flora to lower sickness risk is a growing scientific subject. The intricate network of microorganisms (gut microbiota) in the human intestines regulates many physiological systems and may be important for general health. Rece…

Research on brain functional network property analysis and recognition methods targeting brain fatigue Open

Wei Yan, J. He, Yaoxing Peng, Haozhe Ma, Chunguang Li · 2024

At present, researches on brain fatigue recognition are still in the stage of single task and simple brain region network features, while researches on high-order brain functional network features and brain region state mechanisms during f…

A Medicago truncatula HD-ZIP gene MtHB2 is involved in modulation of root development by regulating auxin response Open

Wei Yan, Runze Wang, Yutong Zhang, Xiuxiu Zhang, Qin Wang · 2024

HD-Zip proteins are plant-specific transcription factors known for their diverse functions in regulating plant growth, development, and responses to environmental stresses. Among the Medicago truncatula HD-Zip II genes, MtHB2 has been prev…

Special issue on “A focus on brain–body communication in understanding the neurobiology of diseases” Open

Kenji Hashimoto, Wei Yan, Chun Yang · 2024

Role of oxidative phosphorylation in the antidepressant effects of arketamine via the vagus nerve-dependent spleen-brain axis Open

Lijia Chang, Wei Yan, Youge Qu, Mingming Zhao, Xiangyu Zhou , et al. · 2024

Arketamine, the (R)-enantiomer of ketamine, exhibits antidepressant-like effects in mice, though the precise molecular mechanisms remain elusive. It has been shown to reduce splenomegaly and depression-like behaviors in the chronic social …

eLife Assessment: Characterisation and comparison of semen microbiota and sperm function in men with infertility, recurrent miscarriage, or proven fertility Open

Wei Yan · 2024

Comparison of endoscopic thyroidectomy via the oral vestibule approach and the areola approach for papillary thyroid carcinoma Open

Yingying Liu, Fusheng Lin, Wei Yan, Ende Lin, Penghao Kuang , et al. · 2024

Human umbilical cord-derived mesenchymal stromal cells improve myocardial fibrosis and restore miRNA-133a expression in diabetic cardiomyopathy Open

Boxin Liu, Wei Yan, Jingjing He, Baofeng Feng, Yimeng Chen , et al. · 2024

A new model for dynamic mapping of effective connectivity in task fMRI Open

Xin Chang, Zhihuan Yang, Wei Yan, Ze-tao Liu, Cheng Luo , et al. · 2024

Whole-brain dynamic functional connectivity is a growing area in neuroimaging research, encompassing data-driven methods for investigating how large-scale brain networks dynamically reorganize during resting states. However, this approach …

Identification of novel endoplasmic reticulum-related genes and their association with immune cell infiltration in major depressive disorder Open

Lijia Chang, Tong Wang, Youge Qu, Xinrong Fan, Xiangyu Zhou , et al. · 2024

These findings indicate that ERDEGs especially including ERLIN1, SEC61B, and USP13 associated the infiltration of immune cells may be potential diagnostic indicators for MDD.

Amelioration of diabetic nephropathy in mice by a single intravenous injection of human mesenchymal stromal cells at early and later disease stages is associated with restoration of autophagy Open

Jingjing He, Boxin Liu, Xiaofeng Du, Wei Yan, Desheng Kong , et al. · 2024

Association of hypoglycemic events with cognitive impairment in patients with type 2 diabetes mellitus: Protocol for a dose-response meta-analysis Open

Min Ye, A. Yuan, Qi Qi Yang, Q. Li, Fei Li , et al. · 2024

Introduction With an incidence rate as high as 46%-58%, hypoglycemia is a common complication of glycemic management among those suffering from type 2 diabetes mellitus(T2DM). According to preclinical research, hypoglycemia episodes may im…

TGR5 signalling in heart and brain injuries: focus on metabolic and ischaemic mechanisms Open

Nan‐Jie Xu, Yufeng He, Chunyu Zhang, Yongqiang Zhang, Shengjie Cheng , et al. · 2024

The heart and brain are the core organs of the circulation and central nervous system, respectively, and play an important role in maintaining normal physiological functions. Early neuronal and cardiac damage affects organ function. The re…

Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high‐fat diet Open

Guohui Xiao, Wei Yan, Rongli Xie, Yiusing Tsang, Jianhua Gu , et al. · 2024

Over the years, pancreatic cancer has experienced a global surge in incidence and mortality rates, largely attributed to the influence of obesity and diabetes mellitus on disease initiation and progression. In this study, we investigated t…

Mapping of health technology assessment in China: a comparative study between 2016 and 2021 Open

Shimeng Liu, Yu Xia, Yi Yang, Jian Ming, Hui Sun , et al. · 2024

Background Health Technology Assessment (HTA) in China has recently expanded from purely academic research to include policy or decision-oriented practice, especially after HTA evidence was used to update the National Reimbursement Drug Li…

Right superior frontal gyrus: A potential neuroimaging biomarker for predicting short-term efficacy in schizophrenia Open

Yongfeng Yang, Xueyan Jin, Yongjiang Xue, Xue Li, Yi Chen , et al. · 2024

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