Xiaoni Yuan
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View article: Posttransplant de novo DSA and NDSA affect GvHD, OS, and DFS after haplo-HSCT in patients without pre-existing HLA antibodies of hematological malignancies
Posttransplant de novo DSA and NDSA affect GvHD, OS, and DFS after haplo-HSCT in patients without pre-existing HLA antibodies of hematological malignancies Open
To examine the production time, type, and MFI of post-transplantation de novo HLA antibodies, and their effects on haplo-HSCT outcomes, we retrospectively included 116 patients who were negative for pre-existing HLA antibodies. In total, 3…
View article: Human leukocyte antigen (HLA) A-C-B-DRB1-DQB1 haplotype segregation analysis among 2152 families in China and the comparison to expectation-maximization algorithm result
Human leukocyte antigen (HLA) A-C-B-DRB1-DQB1 haplotype segregation analysis among 2152 families in China and the comparison to expectation-maximization algorithm result Open
Human leukocyte antigen (HLA) is the major histocompatibility complex for humans. Previous studies have shown that high-resolution HLA matching can reduce graft vs. host disease and improve the outcome of hematopoietic stem cell transplant…
View article: [The role of different KIR haplotypes in haplo-identical hematopoietic stem cell transplantation].
[The role of different KIR haplotypes in haplo-identical hematopoietic stem cell transplantation]. Open
Overall, KIR genotyping and haplotype analyses should be useful for selection of the most optimal donors with favorable KIR gene grafts. KIR gene mismatch donors should be preferred for AML/MDS patients. Selecting donors carried Cen- B and…