Xiao‐Peng He
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View article: Enzyme-encapsulated MOFs containing flexible linkers for the detection of H<sub>2</sub>O<sub>2</sub>
Enzyme-encapsulated MOFs containing flexible linkers for the detection of H<sub>2</sub>O<sub>2</sub> Open
View article: Click conjugation of trivalent mannosyl glycocluster with human serum albumin to generate a cell targeting delivery vehicle
Click conjugation of trivalent mannosyl glycocluster with human serum albumin to generate a cell targeting delivery vehicle Open
The exploitation of glycans as targeting agents to construct delivery materials has proved useful for targeted disease diagnosis and therapy. To achieve effective targeting, multivalent glycosides are prepared to enhance avidity with sugar…
View article: Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe
Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe Open
Metabolic dysfunction‐associated steatotic liver disease (MASLD) has become an important liver disease worldwide due to the rising rate of type 2 diabetes, obesity, and other metabolic disorders. The early detection of MASLD is vital to sl…
View article: CCDC 2294282: Experimental Crystal Structure Determination
CCDC 2294282: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: What Is the Anatomic Footprint of the Anterolateral Ligament of the Knee? A Race- and Sex-based MRI Analysis
What Is the Anatomic Footprint of the Anterolateral Ligament of the Knee? A Race- and Sex-based MRI Analysis Open
Background The anatomic location of the anterolateral ligament (ALL) of the knee is critical to ALL reconstruction, but there is not a clear consensus about the location of its footprint. Knowledge of the anatomic footprint is necessary to…
View article: Construction of a self-assembled duplexed aptasensor for the simultaneous detection of haemoglobin and glycated haemoglobin
Construction of a self-assembled duplexed aptasensor for the simultaneous detection of haemoglobin and glycated haemoglobin Open
A duplexed aptasensor was developed for the simultaneous determination of haemoglobin and glycated haemoglobin in calibration samples.
View article: Twisted intramolecular charge transfer (TICT) based fluorescent probes and imaging agents
Twisted intramolecular charge transfer (TICT) based fluorescent probes and imaging agents Open
Twisted Intramolecular charge transfer (TICT)-based fluorescent probes are crucial in chemical sensing due to their sensitivity and specificity.
View article: A BODIPY-tagged trivalent glycocluster for receptor-targeting fluorescence imaging of live cells
A BODIPY-tagged trivalent glycocluster for receptor-targeting fluorescence imaging of live cells Open
We synthesized a trivalent galactosyl BODIPY probe for the super-resolution (STED) imaging of the dynamic endocytic action of asialoglycoprotein receptor (ASGPr).
View article: Fluorogenic Peptide Sensor Array Derived from Angiotensin-Converting Enzyme 2 Classifies Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern
Fluorogenic Peptide Sensor Array Derived from Angiotensin-Converting Enzyme 2 Classifies Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern Open
The devastating COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made society acutely aware of the urgency in developing effective techniques to timely monitor the outbreak of previously unknown …
View article: Theranostic Fluorescent Probes
Theranostic Fluorescent Probes Open
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal control, in the context of drug delivery makes theranostic fluorescent probes an attractive and intensely investigated research topic. This interest i…
View article: Isoindoline-based fluorogenic probes bearing a self-immolative linker for the sensitive and selective detection of O-GlcNAcase activity
Isoindoline-based fluorogenic probes bearing a self-immolative linker for the sensitive and selective detection of O-GlcNAcase activity Open
An isoindoline-based fluorogenic probe bearing a self-immolative linker was developed for the sensitive and selective detection of O-GlcNAcase.
View article: Non-natural sialic acid derivatives with <i>o</i>-nitrobenzyl alcohol substituents for light-mediated protein conjugation and cell imaging
Non-natural sialic acid derivatives with <i>o</i>-nitrobenzyl alcohol substituents for light-mediated protein conjugation and cell imaging Open
We have synthesized two sialic acid derivatives substituted with an ortho -nitrobenzyl alcohol (o-NBA) group that can undergo light-mediated conjugation with primary amines at their 5- or 9-carbon position.
View article: Selective FRET nano probe based on carbon dots and naphthalimide–isatin for the ratiometric detection of peroxynitrite in drug-induced liver injury
Selective FRET nano probe based on carbon dots and naphthalimide–isatin for the ratiometric detection of peroxynitrite in drug-induced liver injury Open
Ratiometric FRET-based probe CD–N-I was developed to detect exogenous ONOO − in live cells and endogenous ONOO − in APAP-induced liver injury of HepG2 cells.
View article: Editorial: Frontiers in Chemistry: rising stars 2022
Editorial: Frontiers in Chemistry: rising stars 2022 Open
As guest editors of the 2022 Edition of our Frontiers in Chemistry “Rising Stars” article collection, we are delighted to showcase a collection of high-quality work of internationally recognized researchers in the early stages of their ind…
View article: Targeted Near-Infrared Fluorescence Imaging of Liver Cancer using Dual-Peptide-Functionalized Albumin Particles
Targeted Near-Infrared Fluorescence Imaging of Liver Cancer using Dual-Peptide-Functionalized Albumin Particles Open
Fluorescence imaging is an emerging strategy for preoperative diagnosis and intraoperative resection. In particular, owing to their outstanding spatial resolution and deep-tissue penetration, imaging agents in the near-infrared (NIR)-II wi…
View article: Welcome to Fluorescent Chemosensors
Welcome to Fluorescent Chemosensors Open
We would like to welcome you to the wonderful world of fluorescent chemosensors. This book consists of 16 chapters that take you on a journey from receptor-based to reaction-based sensing systems. The quest includes both molecular-based an…
View article: A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species
A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species Open
A nitroreductase (NTR) responsive fluorescent probe with long wavelength fluorescence emission was used to determine the NTR activity of a selection of bacterial species under a range of different bacterial growth conditions.
View article: Human serum albumin-based supramolecular host–guest boronate probe for enhanced peroxynitrite sensing
Human serum albumin-based supramolecular host–guest boronate probe for enhanced peroxynitrite sensing Open
Host–guest inclusion of a small-molecule fluorescent probe into human serum albumin enhances its sensitivity for ONOO − in aqueous solution and in cells.
View article: The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy
The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy Open
This tutorial review provides a general overview for the design of prodrugs and activatable phototherapeutics which enables the development of improved therapies.
View article: Targeted photothermal release of antibiotics by a graphene nanoribbon-based supramolecular glycomaterial
Targeted photothermal release of antibiotics by a graphene nanoribbon-based supramolecular glycomaterial Open
A supramolecular glycomaterial has been developed using the self-assembly of pyrenyl glycosides and graphene nanoribbon-based nanowires for the targeted, photothermally-controlled release of antibiotics to bacteria.
View article: Ratiometric sensing of β-galactosidase based on excited-state intramolecular proton transfer (ESIPT) and solid-state luminescence enhancement
Ratiometric sensing of β-galactosidase based on excited-state intramolecular proton transfer (ESIPT) and solid-state luminescence enhancement Open
An ESIPT-based ratiometric probe with solid-state luminescence enhancement is developed for the sensitive detection of glycosidase activity.
View article: Metal–organic framework (MOF) hybridized gold nanoparticles as a bifunctional nanozyme for glucose sensing
Metal–organic framework (MOF) hybridized gold nanoparticles as a bifunctional nanozyme for glucose sensing Open
Inspired by natural enzymes that possess multiple catalytic activities, here we develop a bifunctional metal–organic frame-work (MOF) for biosensing applications.
View article: Rapid identification of molecular subtyping of breast cancer cell lines using a multi-channel sensor array
Rapid identification of molecular subtyping of breast cancer cell lines using a multi-channel sensor array Open
A multi-channel sensor array composed of three fluorescent units is constructed to differentiate and identify molecular subtypes of breast cancer.
View article: Repurposing a long-wavelength fluorescent boronate probe for the detection of reactive oxygen species (ROS) in bacteria
Repurposing a long-wavelength fluorescent boronate probe for the detection of reactive oxygen species (ROS) in bacteria Open
A TCF boronate based probe developed for cellular imaging was repurposed to detect ROS in bacteria.
View article: Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore
Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore Open
A turn-on isatin receptor based naphthalimide fluorescent probe encapsulated in PEG was used to rapidly detect peroxynitrite in cells.
View article: Fluorescent probes for the detection of chemical warfare agents
Fluorescent probes for the detection of chemical warfare agents Open
In this review, we comprehensively summarize the fluorescent probes reported in the literature for all known kinds of chemical warfare agents (CWAs).
View article: Fluorescent probes and functional materials for biomedical applications
Fluorescent probes and functional materials for biomedical applications Open
Due to their simplicity in preparation, sensitivity and selectivity, fluorescent probes have become the analytical tool of choice in a wide range of research and industrial fields, facilitating the rapid detection of chemical substances of…
View article: Fluorescent probes for the detection of disease-associated biomarkers
Fluorescent probes for the detection of disease-associated biomarkers Open
View article: TCF-based fluorescent probe for monitoring superoxide anion produced in bacteria under chloramphenicol- and heat-induced stress
TCF-based fluorescent probe for monitoring superoxide anion produced in bacteria under chloramphenicol- and heat-induced stress Open
We report on a superoxide anion (O 2 ˙ − ) responsive fluorescent probe called TCF-OTf.
View article: Molecularly engineered AIEgens with enhanced quantum and singlet-oxygen yield for mitochondria-targeted imaging and photodynamic therapy
Molecularly engineered AIEgens with enhanced quantum and singlet-oxygen yield for mitochondria-targeted imaging and photodynamic therapy Open
Luminogens characteristic of aggregation-induced emission (AIEgens) have been engineered for the development of imaging-guided photodynamic therapeutic (PDT) agents.