Xiaoping Pan
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View article: Investigation of region-of-interest-based functional connectivity within the default mode network among adolescents with depression complicated by obesity
Investigation of region-of-interest-based functional connectivity within the default mode network among adolescents with depression complicated by obesity Open
Background This study utilized resting-state functional magnetic resonance imaging (rs-fMRI) combined with default mode network (DMN) region-of-interest (ROI)-based functional connectivity (FC) analysis to examine adolescents with depressi…
View article: Causal relationship of body mass index with autoimmune liver diseases mediated by circulating cytokines: A Mendelian randomization study
Causal relationship of body mass index with autoimmune liver diseases mediated by circulating cytokines: A Mendelian randomization study Open
Observational studies suggest associations between elevated body mass index (BMI) and autoimmune liver diseases (AILDs), yet causal evidence remains limited. This Mendelian randomization (MR) study aimed to elucidate the causal role of BMI…
View article: A study of seed-point-based functional connectivity in the default network of patients with adolescent depression complicated by obesity
A study of seed-point-based functional connectivity in the default network of patients with adolescent depression complicated by obesity Open
BACKGROUD: This study utilized resting-state functional magnetic resonance imaging (rs-fMRI) combined with default mode network (DMN) seed-point-based functional connectivity (FC) analysis to examine adolescents with depression complicated…
View article: Tricellulin facilitates colorectal cancer metastasis through activation of the TGFβ/SMAD2/3 signalling pathway
Tricellulin facilitates colorectal cancer metastasis through activation of the TGFβ/SMAD2/3 signalling pathway Open
Background Tricellulin belongs to the TAMP family of proteins and is primarily localized at the tricellular tight junctions. While its role in the progression of cancer has been reported, its importance in the progression of colorectal can…
View article: Sodium Benzoate Promotes Fat Accumulation and Aging via the SKN-1/Nrf2 Signaling Pathway: Evidence from the<i>Caenorhabditis elegans</i>Model
Sodium Benzoate Promotes Fat Accumulation and Aging via the SKN-1/Nrf2 Signaling Pathway: Evidence from the<i>Caenorhabditis elegans</i>Model Open
Sodium benzoate (SB) is widely used in food products, cosmetics, and medical solutions due to its antimicrobial properties. While it is generally considered safe and has potential neuroprotective benefits, SB has also been linked to advers…
View article: Diversity, Variance, and Stability of Root Phenes of Peanut (<i>Arachis hypogaea</i> L.)
Diversity, Variance, and Stability of Root Phenes of Peanut (<i>Arachis hypogaea</i> L.) Open
Root phenes are associated with the absorptive efficiency of water and fertilizers. However, there are few reports on the genetic variation and stability of peanut ( Arachis hypogaea L.) root architecture under different environments. In t…
View article: Whole transcriptome sequencing analysis revealed key RNA profiles in primary Sjögren's syndrome
Whole transcriptome sequencing analysis revealed key RNA profiles in primary Sjögren's syndrome Open
Background The pathogenesis of Primary Sjögren's syndrome (pSS) is complex and no definite conclusions have been reached. Accumulating evidence suggests that non-coding RNAs (ncRNAs) are involved in the pathogenesis of pSS. However, regula…
View article: Pyramiding of gn1a, gs3, and ipa1 Exhibits Complementary and Additive Effects on Rice Yield
Pyramiding of gn1a, gs3, and ipa1 Exhibits Complementary and Additive Effects on Rice Yield Open
Pyramiding of quantitative trait loci (QTLs) is a powerful approach in breeding super-high-yield varieties. However, the performance of QTLs in improving rice yield varies with specific genetic backgrounds. In a previous study, we employed…
View article: Differential Responses of Wheat (Triticum aestivum L.) and Cotton (Gossypium hirsutum L.) to Nitrogen Deficiency in the Root Morpho-Physiological Characteristics and Potential MicroRNA-Mediated Mechanisms
Differential Responses of Wheat (Triticum aestivum L.) and Cotton (Gossypium hirsutum L.) to Nitrogen Deficiency in the Root Morpho-Physiological Characteristics and Potential MicroRNA-Mediated Mechanisms Open
Understanding the mechanism of crop response to nitrogen (N) deficiency is very important for developing sustainable agriculture. In addition, it is unclear if the microRNA-mediated mechanism related to root growth complies with a common m…
View article: Response of Root Growth and Development to Nitrogen and Potassium Deficiency as well as microRNA-Mediated Mechanism in Peanut (Arachis hypogaea L.)
Response of Root Growth and Development to Nitrogen and Potassium Deficiency as well as microRNA-Mediated Mechanism in Peanut (Arachis hypogaea L.) Open
The mechanism of miRNA-mediated root growth and development in response to nutrient deficiency in peanut ( Arachis hypogaea L.) is still unclear. In the present study, we found that both nitrogen (N) and potassium (K) deficiency resulted i…
View article: Integrating systematic biological and proteomics strategies to explore the pharmacological mechanism of danshen yin modified on atherosclerosis
Integrating systematic biological and proteomics strategies to explore the pharmacological mechanism of danshen yin modified on atherosclerosis Open
This research utilized the systematic biological and proteomics strategies to explore the regulatory mechanism of Danshen Yin Modified (DSYM) on atherosclerosis (AS) biological network. The traditional Chinese medicine database and HPLC wa…
View article: Potassium Deficiency Significantly Affected Plant Growth and Development as Well as microRNA-Mediated Mechanism in Wheat (Triticum aestivum L.)
Potassium Deficiency Significantly Affected Plant Growth and Development as Well as microRNA-Mediated Mechanism in Wheat (Triticum aestivum L.) Open
It is well studied that potassium (K+) deficiency induced aberrant growth and development of plant and altered the expression of protein-coding genes. However, there are not too many systematic investigations on root development affected b…
View article: Small RNA Sequencing Reveals Regulatory Roles of MicroRNAs in the Development of Meloidogyne incognita
Small RNA Sequencing Reveals Regulatory Roles of MicroRNAs in the Development of Meloidogyne incognita Open
MicroRNAs (miRNAs) are an extensive class of small regulatory RNAs. Knowing the specific expression and functions of miRNAs during root-knot nematode (RKN) (Meloidogyne incognita) development could provide fundamental information about RKN…
View article: Whole Genome Sequencing of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli Isolated From a Wastewater Treatment Plant in China
Whole Genome Sequencing of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli Isolated From a Wastewater Treatment Plant in China Open
Our study revealed the resistome of a pharmaceutical WWTP by both culture-dependent and metegenomic methods. The existence of ESBL-producing E. coli strains, indicating that pharmaceutical WWTP can play a significant role in the emergence …
View article: Reassessment of the Four Yield-related Genes Gn1a, DEP1, GS3, and IPA1 in Rice Using a CRISPR/Cas9 System
Reassessment of the Four Yield-related Genes Gn1a, DEP1, GS3, and IPA1 in Rice Using a CRISPR/Cas9 System Open
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated (Cas) systems have been successfully used as efficient tools for genome editing in a variety of species. We used the CRISPR/Cas9 system to mutate the Gn1a (Os01g…