Yunhai Zhang
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View article: Human umbilical cord mesenchymal stem cells ameliorates cisplatin-induced blood-testis barrier dysfunction in mice by mitigating ferroptosis
Human umbilical cord mesenchymal stem cells ameliorates cisplatin-induced blood-testis barrier dysfunction in mice by mitigating ferroptosis Open
View article: miR-34c regulates the proliferation, apoptosis, and testosterone synthesis of bovine leydig cells by targeted ATG5 gene
miR-34c regulates the proliferation, apoptosis, and testosterone synthesis of bovine leydig cells by targeted ATG5 gene Open
The reproductive potential of bull represents a key economic trait in modern cattle husbandry. The primary determinant of bull reproductive capacity is the proper development of the testes, which is essential for the production of spermato…
View article: Design, commissioning, and first operation of the high-temperature superconducting tokamak Honghuang70
Design, commissioning, and first operation of the high-temperature superconducting tokamak Honghuang70 Open
View article: Spermidine supplementation protects porcine oocytes from triclosan-induced meiotic and fertilization defects by attenuating oxidative stress-mediated apoptosis
Spermidine supplementation protects porcine oocytes from triclosan-induced meiotic and fertilization defects by attenuating oxidative stress-mediated apoptosis Open
Oocytes are highly susceptible to environmental pollutants, with triclosan (TCS)—a pervasive antimicrobial—known to bioaccumulate and impair reproductive function. However, mechanisms driving TCS-induced oocyte degeneration and effective p…
View article: Exposure to nanoscale graphene oxide deteriorates the quality of porcine oocytes via induction of oxidative stress and the apoptosis
Exposure to nanoscale graphene oxide deteriorates the quality of porcine oocytes via induction of oxidative stress and the apoptosis Open
View article: Rational tailoring of electron-donating arms toward promising thia[5]helicene-based hole-transporters for stable and efficient perovskite solar cells
Rational tailoring of electron-donating arms toward promising thia[5]helicene-based hole-transporters for stable and efficient perovskite solar cells Open
View article: Chronic kidney disease as a catalyst for cerebral microbleeds: understanding the underlying mechanisms and treatment approaches
Chronic kidney disease as a catalyst for cerebral microbleeds: understanding the underlying mechanisms and treatment approaches Open
Cerebral microbleeds (CMBs) are tiny deposits of blood degradation products in the brain that appear as small, low-signal lesions on magnetic resonance imaging paramagnetic susceptibility sequences. They are common forms of the cerebral sm…
View article: Weaning management in a patient with heart dysfunction: a case report
Weaning management in a patient with heart dysfunction: a case report Open
Background Patients undergoing weaning from mechanical ventilation face the risks of reintubation. Spontaneous breathing trials (SBTs), including T-piece (SBT-T) and pressure support (SBT-P), are commonly used to assess extubation readines…
View article: Effects of Mogroside V on Quality and Antioxidant Activity of Boar Frozen–Thawed Sperm
Effects of Mogroside V on Quality and Antioxidant Activity of Boar Frozen–Thawed Sperm Open
Cryopreserved pig semen tends to produce excessive reactive oxygen species (ROS) during the thawing process, which leads to a decline in semen quality during in vitro storage. Mogroside V (MV) has been proven to be an effective antioxidant…
View article: Experimental Study on the Effect of the Spray Time on the Deflagration Characteristics of Oil Mist in a Closed Chamber
Experimental Study on the Effect of the Spray Time on the Deflagration Characteristics of Oil Mist in a Closed Chamber Open
The deflagration of oil mist in closed chambers often causes severe ship fire accidents. Based on a self-built visual oil mist deflagration experiment platform, this research analyzed the effect of the spray time on the oil mist deflagrati…
View article: ELF5 gene promotes milk lipid synthesis in goat mammary epithelial cells by transcriptomic analysis
ELF5 gene promotes milk lipid synthesis in goat mammary epithelial cells by transcriptomic analysis Open
E74-like factor 5 (ELF5) is an Ets transcription factor of epithelial development, while the function of ELF5 gene in goat milk fat synthesis remains to be elucidated. In goat mammary epithelial cells, we performed RNA sequencing and analy…
View article: Transcriptome and DNA methylation analysis of the goat pineal gland during puberty
Transcriptome and DNA methylation analysis of the goat pineal gland during puberty Open
View article: Multi-methoxy regulation of carbazole molecules as prospective hole transporting layers for stable perovskite solar cells
Multi-methoxy regulation of carbazole molecules as prospective hole transporting layers for stable perovskite solar cells Open
View article: Duxa Regulates the Early Development of Porcine Cloned Embryos
Duxa Regulates the Early Development of Porcine Cloned Embryos Open
View article: Gene horizontal transfers and functional diversity negatively correlated with bacterial taxonomic diversity along a nitrogen gradient
Gene horizontal transfers and functional diversity negatively correlated with bacterial taxonomic diversity along a nitrogen gradient Open
View article: Host-induced gene silencing of specific genes of Plasmodiophora brassicae as an approach to control clubroot disease
Host-induced gene silencing of specific genes of Plasmodiophora brassicae as an approach to control clubroot disease Open
Clubroot disease, caused by the biotrophic pathogen Plasmodiophora brassicae, poses a significant threat to global cruciferous crops production. Current prevention and control strategies are ineffective against P. brassicae. Therefore, new…
View article: Transcriptome and DNA Methylation Analysis of the Goat Pineal Gland During Puberty
Transcriptome and DNA Methylation Analysis of the Goat Pineal Gland During Puberty Open
Epigenetic regulation of gene transcription may play a critical role in the onset of puberty. Previous studies have confirmed that methylation regulates gene transcription in the hypothalamus-pituitary-gonadal axis during puberty initiatio…
View article: Ring-shaped segmentation phase design method for the combined point spread function
Ring-shaped segmentation phase design method for the combined point spread function Open
The study presents a method for designing phase masks, specifically the ring-shaped segmentation method, which can be employed in creating the modulation phase for specialized point spread functions (PSFs), such as multi-focus PSFs and tho…
View article: Genome-Wide Identification and Evolutionary and Mutational Analysis of the Bos taurus Pax Gene Family
Genome-Wide Identification and Evolutionary and Mutational Analysis of the Bos taurus Pax Gene Family Open
Bos taurus is known for its tolerance of coarse grains, adaptability, high temperature, humidity, and disease resistance. Primarily, cattle are raised for their meat and milk, and pinpointing genes associated with traits relevant to meat p…
View article: Kinesin motor <scp>KIF16A</scp> regulates microtubule stability and actin‐dependent spindle migration in mouse oocyte meiosis
Kinesin motor <span>KIF16A</span> regulates microtubule stability and actin‐dependent spindle migration in mouse oocyte meiosis Open
Kif16A, a member of the kinesin‐3 family of motor proteins, has been shown to play crucial roles in inducing mitotic arrest, apoptosis, and mitotic cell death. However, its roles during oocyte meiotic maturation have not been fully defined…
View article: Identifying differentially expressed genes in goat mammary epithelial cells induced by overexpression of SOCS3 gene using RNA sequencing
Identifying differentially expressed genes in goat mammary epithelial cells induced by overexpression of SOCS3 gene using RNA sequencing Open
The suppressor of cytokine signaling 3 (SOCS3) is a key signaling molecule that regulates milk synthesis in dairy livestock. However, the molecular mechanism by which SOCS3 regulates lipid synthesis in goat milk remains unclear. This study…
View article: Bioinspired Bone Seed 3D‐Printed Scaffold via Trapping Black Phosphorus Nanosheet for Bone Regeneration
Bioinspired Bone Seed 3D‐Printed Scaffold via Trapping Black Phosphorus Nanosheet for Bone Regeneration Open
Significance of endogenous mineralization in bone reconstruction is paramount, as it facilitates the accumulation of calcium ions for bone tissue deposition. However, conventional 3D‐printed scaffolds lack the capacity for calcium ion enri…
View article: Characterization of sexual maturity-associated N6-methyladenosine in boar testes
Characterization of sexual maturity-associated N6-methyladenosine in boar testes Open
Background The health and size of the testes are crucial for boar fertility. Testicular development is tightly regulated by epigenetics. N6-methyladenosine (m6A) modification is a prevalent internal modification on mRNA and plays an import…
View article: circKIF27 inhibits melanogenesis and proliferation by targeting miR-129-5p/TGIF2 pathway in goat melanocytes
circKIF27 inhibits melanogenesis and proliferation by targeting miR-129-5p/TGIF2 pathway in goat melanocytes Open
View article: Ezrin Thr567 phosphorylation participates in mouse oocyte maturation, fertilization, and early embryonic development
Ezrin Thr567 phosphorylation participates in mouse oocyte maturation, fertilization, and early embryonic development Open
Background Ezrin is a membrane-cytoskeleton linker, involved in cell polarization, cell migration, cell division, signal transduction and some other cellular activities that play an important role in oocyte maturation, fertilization and ea…
View article: Analysis of fecal microbiome and metabolome changes in goats with pregnant toxemia
Analysis of fecal microbiome and metabolome changes in goats with pregnant toxemia Open
Background Pregnancy toxemia is a common disease, which occurs in older does that are pregnant with multiple lambs in the third trimester. Most of the sick goats die within a few days, which can seriously impact the economic benefits of go…
View article: Increase in Mineral-Associated Organic Carbon Does Not Offset the Decrease in Particulate Organic Carbon Under Long-Term Nitrogen Enrichment in a Steppe Ecosystem
Increase in Mineral-Associated Organic Carbon Does Not Offset the Decrease in Particulate Organic Carbon Under Long-Term Nitrogen Enrichment in a Steppe Ecosystem Open
View article: A Robust Zro2 Rectifier Layer Derived from Uio-66 Enable Ultra-High Nickel Cathodes with High Stability and Ion Transport Kinetics for Lithium-Ion Batteries
A Robust Zro2 Rectifier Layer Derived from Uio-66 Enable Ultra-High Nickel Cathodes with High Stability and Ion Transport Kinetics for Lithium-Ion Batteries Open
View article: 18S ribosomal RNA methyltransferase METTL5-mediated CDX2 translation regulates porcine early embryo development
18S ribosomal RNA methyltransferase METTL5-mediated CDX2 translation regulates porcine early embryo development Open
N6-methyladenosine (m6A) plays a key role in mammalian early embryonic development and cell lineage differentiation. However, the role and mechanisms of 18S ribosomal RNA (rRNA) m6A methyltransferase METTL5 in early embryonic development r…
View article: Integrative proteomic and phosphoproteomic analysis in the female goat hypothalamus to study the onset of puberty
Integrative proteomic and phosphoproteomic analysis in the female goat hypothalamus to study the onset of puberty Open
Background Puberty marks the end of childhood and achieve sexual maturation and fertility. The role of hypothalamic proteins in regulating puberty onset is unclear. We performed a comprehensive differential proteomics and phosphoproteomics…