Xianjing Liu
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View article: Perceptions, Definitions, and Preparedness Regarding Low-Performing and Impaired Colleagues in Cardiothoracic and Vascular Anesthesia: An International Survey
Perceptions, Definitions, and Preparedness Regarding Low-Performing and Impaired Colleagues in Cardiothoracic and Vascular Anesthesia: An International Survey Open
A consensus-based definition of LPC-CTVA has been established. However, institutional readiness and clinician confidence remain limited. Experience and structured systems enhance response capability.
View article: Genetic Insights of Image-Based Traits: Analysis Pipeline for AI-based Phenotyping, Combined-GWAS, and Federated Learning with Application to the Human Face
Genetic Insights of Image-Based Traits: Analysis Pipeline for AI-based Phenotyping, Combined-GWAS, and Federated Learning with Application to the Human Face Open
Image-derived phenotypes - traits extracted from biological images - capture rich morphological information and understanding their genetic basis is crucial for elucidating developmental mechanisms and linking genetic variation to complex …
View article: Facial asymmetry in syndromic craniosynostosis patients undergoing midface surgery compared to a large general population
Facial asymmetry in syndromic craniosynostosis patients undergoing midface surgery compared to a large general population Open
This study aimed to assess mean facial asymmetry (MFA) before and after midface surgery (Le Fort III, monobloc, or facial bipartition) in syndromic craniosynostosis patients and compare it to the general population. This retrospective stud…
View article: Evaluation of an Electronic Application for Enhancing Medication Adherence Among Hypertensive Patients: A Qualitative Research Based on Consolidated Framework for Implementation Research (CFIR)
Evaluation of an Electronic Application for Enhancing Medication Adherence Among Hypertensive Patients: A Qualitative Research Based on Consolidated Framework for Implementation Research (CFIR) Open
Background and Aims Patient adherence plays a crucial role in effective chronic disease management. eHealth interventions utilizing smartphone applications (apps) are emerging as a promising approach to support adherence. This study aims t…
View article: Global burden of thyroid cancer among adolescents and young adults, 1990-2021, and projections to 2050: an analysis based on the GBD 2021
Global burden of thyroid cancer among adolescents and young adults, 1990-2021, and projections to 2050: an analysis based on the GBD 2021 Open
Objective To evaluate the global burden of thyroid cancer (TC) among adolescents and young adults (AYA) aged 15-39 years from 1990 to 2021, with projections to 2050, and identify demographic and regional disparities. Methods Using Global B…
View article: Perceptions and Attitudes Toward Utilizing a Non‐Invasive Biomarker for Colorectal Cancer Screening: A Qualitative Study
Perceptions and Attitudes Toward Utilizing a Non‐Invasive Biomarker for Colorectal Cancer Screening: A Qualitative Study Open
Background Colorectal cancer (CRC) screening, effective for early detection of CRC, was recently implemented by the Hong Kong government using the quantitative Fecal Immunochemical Test (FIT). However, consistently low participation rates …
View article: The Cost‐Effectiveness of a Multi‐Target Stool <scp>DNA</scp>‐Based Screening (<scp>COLOTECT</scp>), <scp>FIT</scp>, Colonoscopy and No Screening for Colorectal Cancer
The Cost‐Effectiveness of a Multi‐Target Stool <span>DNA</span>‐Based Screening (<span>COLOTECT</span>), <span>FIT</span>, Colonoscopy and No Screening for Colorectal Cancer Open
Background Around 1.9 million new cases and 1 million deaths worldwide were attributed to colorectal cancer (CRC) in 2020. Aims The aims of this study are to assess the cost‐effectiveness of a multi‐target stool DNA‐based screening strateg…
View article: AI-based association analysis for medical imaging using latent-space geometric confounder correction
AI-based association analysis for medical imaging using latent-space geometric confounder correction Open
This study addresses the challenges of confounding effects and interpretability in artificial-intelligence-based medical image analysis. Whereas existing literature often resolves confounding by removing confounder-related information from…
View article: Revisiting the starting age of colorectal cancer screening in Hong Kong: a cost-effectiveness analysis
Revisiting the starting age of colorectal cancer screening in Hong Kong: a cost-effectiveness analysis Open
Background: The incidence of early-onset colorectal cancer (CRC) is rising in Hong Kong. While the existing CRC screening program has been effective, it does not prioritize the prevention of early-onset cases in individuals under 50. This …
View article: Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study
Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study Open
Objective To investigate the association between polycystic ovary syndrome (PCOS) and inflammatory proteins, and to identify and quantify the role of serum metabolites as potential mediators. Methods Utilizing summary-level data from a gen…
View article: The effect of green tea on patients with type 2 diabetes mellitus: A meta-analysis
The effect of green tea on patients with type 2 diabetes mellitus: A meta-analysis Open
Background: To systematically evaluate the effect of green tea on patients with type 2 diabetes. Methods: A computer search Cochrane, PubMed, Embase, CNKI, Wanfang, VIP, and other Chinese and English databases were conducted for randomized…
View article: Development of a risk scoring system for predicting advanced colorectal neoplasia within subcentimetric polyps: A population‐based study
Development of a risk scoring system for predicting advanced colorectal neoplasia within subcentimetric polyps: A population‐based study Open
Objective To determine a risk scoring system for predicting advanced colorectal neoplasia (ACN) within subcentimetric polyps in a large Asian population. Methods A retrospective study was conducted in Hong Kong SAR, China involving partici…
View article: Global burden, risk factors, and temporal trends of ureteral cancer: a comprehensive analysis of cancer registries
Global burden, risk factors, and temporal trends of ureteral cancer: a comprehensive analysis of cancer registries Open
Background Ureteral cancer is a rare cancer. This study aimed to provide an up-to-date and comprehensive analysis on the global trends of ureteral cancer incidence and its association with lifestyle and metabolic risk factors. Methods The …
View article: Automated three-dimensional analysis of facial asymmetry in patients with syndromic coronal synostosis: A retrospective study
Automated three-dimensional analysis of facial asymmetry in patients with syndromic coronal synostosis: A retrospective study Open
Craniosynostosis, characterized by premature fusion of one or more cranial sutures, results in a distorted skull shape. Only three studies have assessed facial asymmetry manually in unicoronal synostosis patients. It is therefore important…
View article: Incidence, risk factors, and temporal trends of penile cancer: a global population‐based study
Incidence, risk factors, and temporal trends of penile cancer: a global population‐based study Open
Objectives To examine the global disease burden and country‐specific trends of penile cancer incidence by age group and investigate its associations with several factors. Materials and Methods The Global Cancer Observatory database was int…
View article: Predicting skin cancer risk from facial images with an explainable artificial intelligence (XAI) based approach: a proof-of-concept study
Predicting skin cancer risk from facial images with an explainable artificial intelligence (XAI) based approach: a proof-of-concept study Open
Background Efficient identification of individuals at high risk of skin cancer is crucial for implementing personalized screening strategies and subsequent care. While Artificial Intelligence holds promising potential for predictive analys…
View article: AI-based association analysis for medical imaging using latent-space geometric confounder correction
AI-based association analysis for medical imaging using latent-space geometric confounder correction Open
AI has greatly enhanced medical image analysis, yet its use in epidemiological population imaging studies remains limited due to visualization challenges in non-linear models and lack of confounder control. Addressing this, we introduce an…
View article: Oral and craniofacial research in the Generation R study: an executive summary
Oral and craniofacial research in the Generation R study: an executive summary Open
Objectives Oral conditions are of high prevalence and chronic character within the general population. Identifying the risk factors and determinants of oral disease is important, not only to reduce the burden of oral diseases, but also to …
View article: Association between prenatal alcohol exposure and children's facial shape: a prospective population-based cohort study
Association between prenatal alcohol exposure and children's facial shape: a prospective population-based cohort study Open
STUDY QUESTION Is there an association between low-to-moderate levels of prenatal alcohol exposure (PAE) and children’s facial shape? SUMMARY ANSWER PAE before and during pregnancy, even at low level (<12 g of alcohol per week), was fou…
View article: MOLECULAR MARKER (PCR-RFLP) ASSISTED IDENTIFICATION OF MEAT SPECIES BY MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT I (COI) GENE
MOLECULAR MARKER (PCR-RFLP) ASSISTED IDENTIFICATION OF MEAT SPECIES BY MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT I (COI) GENE Open
To guard consumers from meat adulteration, there is a dire obligation to encompass a sensitive, simple, and precise way for the identification of meat animal species. Molecular techniques have hoisted the expectations of developing authent…
View article: IN SILICO STRUCTURAL, EVOLUTIONARY, AND EXPRESSION ANALYSIS OF SMALL HEAT SHOCK PROTEIN (SHSP) ENCODING GENES IN COCOA (THEOBROMA CACAO L.)
IN SILICO STRUCTURAL, EVOLUTIONARY, AND EXPRESSION ANALYSIS OF SMALL HEAT SHOCK PROTEIN (SHSP) ENCODING GENES IN COCOA (THEOBROMA CACAO L.) Open
The small heat shock proteins (sHSP) are the molecular chaperones that play important roles in the development and stress responses of plants. However, the sHSP family has not been well investigated in cocoa (Theobroma cacao L.). In this w…
View article: AB032. Factors associated with uptake of cervical cancer screening: a population-based study of 2,305 Chinese females
AB032. Factors associated with uptake of cervical cancer screening: a population-based study of 2,305 Chinese females Open
Background: Cervical cancer screening is one of the most common cancers amongst females. It is also one of the leading causes of female cancer death globally and in Hong Kong. Cervical cancer screening has been suggested as an effective me…
View article: IDDF2021-ABS-0184 Global incidence and risk factors of pancreatic cancer among young adults: an epidemiological study
IDDF2021-ABS-0184 Global incidence and risk factors of pancreatic cancer among young adults: an epidemiological study Open
Background The objective of this study is to examine the incidence and risk factors for pancreatic cancer among younger adults aged 15-49 years old using global and national cancer registry data. Methods We retrieved the Global Cancer Obse…
View article: IDDF2021-ABS-0188 Worldwide incidence and lifestyle risk factors of gastric cancer among young adults: a global study
IDDF2021-ABS-0188 Worldwide incidence and lifestyle risk factors of gastric cancer among young adults: a global study Open
Background The purpose of this study is to investigate the incidence and lifestyle risk factors for gastric cancer in younger individuals aged 15-49 years old using global health and national cancer registry data. Methods We retrieved the …
View article: IDDF2021-ABS-0181 Incidence and risk factors for early-onset colorectal cancer: a global data analysis
IDDF2021-ABS-0181 Incidence and risk factors for early-onset colorectal cancer: a global data analysis Open
Background This study aimed to investigate the incidence of and the risk factors associated with early-onset colorectal cancer (CRC) using data from 185 countries. Methods The Global Cancer Observatory (GLOBOCAN) was retrieved for the age-…