Xiangyan Ruan
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View article: Effect of oral contraceptive pretreatment on IVF outcomes in women with polycystic ovary syndrome using a long GnRH agonist protocol
Effect of oral contraceptive pretreatment on IVF outcomes in women with polycystic ovary syndrome using a long GnRH agonist protocol Open
In PCOS patients, OC pretreatment showed trends toward higher pregnancy rates and lower OHSS, without adverse effects on clinical outcomes. These findings highlight a potentially promising approach, warranting confirmation in larger, high-…
View article: Hypoxia-preconditioned hUCMSCs protect frozen-thawed human ovarian tissue by modulating the HIF-1α/VEGF pathway
Hypoxia-preconditioned hUCMSCs protect frozen-thawed human ovarian tissue by modulating the HIF-1α/VEGF pathway Open
This in vitro study showed that co-culture of ovarian tissue with H-MSCs provides stronger protection than N-MSCs. This effect likely involves the HIF-1α/VEGFA pathway, with enhanced pro-angiogenic signaling, reduced apoptosis and oxidativ…
View article: Advances in ovarian tissue cryopreservation and transplanta-tion for fertility preservation in prepubertal patients
Advances in ovarian tissue cryopreservation and transplanta-tion for fertility preservation in prepubertal patients Open
Ovarian tissue cryopreservation and transplantation is currently the only feasible method for preserving both fertility and ovarian endocrine function in prepubertal female patients. It is indicated for those requiring gonadotoxic therapie…
View article: A Computation of Tamarkin-Tsygan Calculus
A Computation of Tamarkin-Tsygan Calculus Open
We compute the full Tamarkin-Tsygan calculus of a Koszul algebra whose global dimension exceeds the number of generators. Our results show that even for algebras possessing an economic presentation and agreeable homological properties, the…
View article: Comparison of bone mineral density and influencing factors in iatrogenic and idiopathic POI
Comparison of bone mineral density and influencing factors in iatrogenic and idiopathic POI Open
The incidence of osteopenia and osteoporosis in POI patients is high, especially in iatrogenic POI patients, who experience more severe bone loss and a higher incidence of osteoporosis. BMI and a delay in diagnosis significantly affected B…
View article: Diagnostic ultrasound characteristics of Morel-Lavallée lesions: Case and dataset analysis
Diagnostic ultrasound characteristics of Morel-Lavallée lesions: Case and dataset analysis Open
Morel-Lavallée lesions (MLLs) are uncommon closed soft tissue injuries often arising from blunt trauma, characterized by a separation between the subcutaneous tissue and the underlying fascia, leading to fluid accumulation. This case repor…
View article: A clinical efficacy analysis of ankle arthrography-assisted modified ankle capsule repair in the treatment of recurrent bunion cysts
A clinical efficacy analysis of ankle arthrography-assisted modified ankle capsule repair in the treatment of recurrent bunion cysts Open
Objective This study aims to retrospectively analyze the clinical efficacy of ankle arthrography-assisted modified ankle capsular repair for treating recurrent bunion cysts. Methods Clinical data from 16 cases of recurrent bunion cysts, tr…
View article: Fertility preservation by ovarian tissue cryopreservation of children in China——umbilical single-incision surgery and perioperative experience
Fertility preservation by ovarian tissue cryopreservation of children in China——umbilical single-incision surgery and perioperative experience Open
Background Ovarian tissue cryopreservation and transplantation (OTCT) is an effective method for preserving fertility and endocrine function. This study aims to summarize the surgical techniques and perioperative experiences to provide cli…
View article: Changes in menopause-specific quality of life between women with transdermal estradiol versus oral estrogens: results of a randomized controlled trial
Changes in menopause-specific quality of life between women with transdermal estradiol versus oral estrogens: results of a randomized controlled trial Open
This study showed that both transdermal and oral estrogens were highly effective in relieving the overall menopausal symptoms for recently-menopausal women, with little difference in treatment efficacy between the two routes.
View article: Second pregnancy in China 5 years after ovarian tissue transplantation to prevent iatrogenic POI
Second pregnancy in China 5 years after ovarian tissue transplantation to prevent iatrogenic POI Open
Ovarian tissue cryopreservation and transplantation (OTCT) can be assessed as a successful method especially to prevent iatrogenic POI. In our cryobank for OTCT, which is the first official one in China, intensive research to improve this …
View article: [Wrist arthroscopic Wafer surgery combined with triangular fibrocartilage complex insertion point reconstruction in treatment of Palmer type <b>Ⅱ</b>C combined with type <b>Ⅰ</b>B ulnar impingement syndrome].
[Wrist arthroscopic Wafer surgery combined with triangular fibrocartilage complex insertion point reconstruction in treatment of Palmer type <b>Ⅱ</b>C combined with type <b>Ⅰ</b>B ulnar impingement syndrome]. Open
Arthroscopic Wafer surgery combined with TFCC insertion point reconstruction can effectively relieve wrist pain, enhance the stability of the distal radioulnar joint, and restore the function of the wrist in patients with Palmer type ⅡC co…
View article: Ovarian tissue cryopreservation for a girl with combined severe hemolytic anemia due to pyruvate kinase deficiency: a case report and literature review
Ovarian tissue cryopreservation for a girl with combined severe hemolytic anemia due to pyruvate kinase deficiency: a case report and literature review Open
Hematopoietic stem cell transplantation is essential for effective treatment of pyruvate kinase deficiency. We assess OTC as the only possible fertility preservation method for children who cannot undergo embryo and oocyte cryopreservation.
View article: Numerical Study on the Wave Attenuation Performance of a Novel Partial T Special-Type Floating Breakwater
Numerical Study on the Wave Attenuation Performance of a Novel Partial T Special-Type Floating Breakwater Open
Floating breakwaters (FBs) play an important role in protecting coastlines, marine structures, and ports due to their simple construction, convenient movement, cost-effectiveness, and environmental friendliness. However, the traditional bo…
View article: Criteria for the choice and monitoring of Menopausal Hormone Therapy
Criteria for the choice and monitoring of Menopausal Hormone Therapy Open
To review the criteria for the selection of estrogens and especially progestogens for optimizing Menopausal Hormone Therapy (MHT). The main criteria are primarily derived from the Women's Health Initiative (WHI)-trial, disclosing the main …
View article: Standardization for ovarian tissue cryopreservation and transplantation in China
Standardization for ovarian tissue cryopreservation and transplantation in China Open
Ovarian tissue cryopreservation and transplantation is one of the most advanced and promising fertility preservation methods. Prior to any procedure that may lead to a toxic ovarian injury (such as chemotherapy or radiotherapy), a portion …
View article: Ovarian tissue cryopreservation for an 8 year old girl after hematopoietic stem cell transplantation in China: case report and literature review
Ovarian tissue cryopreservation for an 8 year old girl after hematopoietic stem cell transplantation in China: case report and literature review Open
Patients who miss fertility preservation before HSCT should consult fertility preservation and gynecological endocrinology experts as early as possible after HSCT and undergo regular follow-up. If clinical evidence indicates residual ovari…
View article: Evidence-based guideline: premature ovarian insufficiency <sup>†</sup> <sup>‡</sup>
Evidence-based guideline: premature ovarian insufficiency <sup>†</sup> <sup>‡</sup> Open
The guideline provides healthcare professionals with clear advice on best practice in POI care, based on the best evidence currently available. In addition, a list of research recommendations is provided to guide further studies in POI.
View article: Time-efficient consultation hours in the department of gynecological endocrinology
Time-efficient consultation hours in the department of gynecological endocrinology Open
A concise patient history that concentrates on the most relevant points can reduce the total consultation time. Reducing consultation time can be made without compromising how well patients feel consulted.
View article: O-111 Premature ovarian insufficiency: new data and updated guidance
O-111 Premature ovarian insufficiency: new data and updated guidance Open
Premature ovarian insufficiency (POI) presents a significant challenge to women's health, with significant implications both physically and emotionally. Despite its life-altering impact, there remain substantial unknowns in the causes this…
View article: Efficacy and safety of fezolinetant for moderate to severe vasomotor symptoms associated with menopause among women in East Asia: a phase 3 randomized study (MOONLIGHT I)
Efficacy and safety of fezolinetant for moderate to severe vasomotor symptoms associated with menopause among women in East Asia: a phase 3 randomized study (MOONLIGHT I) Open
Objective To evaluate the efficacy and safety of fezolinetant for moderate to severe vasomotor symptoms (VMS) associated with menopause in East Asian women. Methods In this phase 3, randomized, double-blind study, postmenopausal women with…
View article: Evaluating the safety and efficacy of cryopreserved ovarian tissue transplantation in leukemia patients with different bone marrow remission status using xenotransplantation
Evaluating the safety and efficacy of cryopreserved ovarian tissue transplantation in leukemia patients with different bone marrow remission status using xenotransplantation Open
Background Leukemia patients undergoing cryopreserved ovarian tissue transplantation (OTT) may carry a high risk of disease induction. Measurable residual disease (MRD) in bone marrow is linked to an elevated risk of relapse. It is controv…
View article: Evidence-based guideline: premature ovarian insufficiency,
Evidence-based guideline: premature ovarian insufficiency, Open
STUDY QUESTION How should premature/primary ovarian insufficiency (POI) be diagnosed and managed based on the best available evidence from published literature? SUMMARY ANSWER The current guideline provides 145 recommendations on symptoms,…
View article: P1154 Mediterranean dietary approaches to stop hypertension intervention for neurodegenerative delay (MIND) diet can reduce Inflammatory Bowel Disease risk: a prospective cohort study
P1154 Mediterranean dietary approaches to stop hypertension intervention for neurodegenerative delay (MIND) diet can reduce Inflammatory Bowel Disease risk: a prospective cohort study Open
Background The global increasing prevalence of Inflammatory Bowel Diseases (IBD) places a substantial burden on families and society at large. The lack of a definitive cure for this chronic condition underscores the critical need for effec…
View article: Chinese Expert Consensus on ovarian function and fertility preservation of cervical cancer in pregnancy (2023)
Chinese Expert Consensus on ovarian function and fertility preservation of cervical cancer in pregnancy (2023) Open
Cervical cancer in pregnancy (CCIP) refers to cervical cancer diagnosed during pregnancy, the most common gynecological malignant tumor. Because of the special physiological changes of CCIP, although preserving ovarian function and fertili…
View article: Effects of different volumes of ovariectomy on fertility and offspring development of rats
Effects of different volumes of ovariectomy on fertility and offspring development of rats Open
Objective The purpose of this study was to explore the effect of removal of different volumes of ovarian tissue on fertility and offspring development of SD rats. Methods SD rats were randomly divided into 6 groups according to different v…
View article: Effect of physical exercise on sleep quality in college students: Mediating role of smartphone use
Effect of physical exercise on sleep quality in college students: Mediating role of smartphone use Open
Objective To investigate the effect of physical exercise on sleep quality and the mediating effect of smartphone use behavior in college students. Methods A cross-sectional study design was adopted. An online survey of 5,075 college studen…