Xiaowei Huo
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View article: Salvianolic acid A targets glutamic-oxaloacetic transaminase 2 to ameliorate doxorubicin-induced myocardial oxidative injury by activating malate-aspartate NADH shuttle
Salvianolic acid A targets glutamic-oxaloacetic transaminase 2 to ameliorate doxorubicin-induced myocardial oxidative injury by activating malate-aspartate NADH shuttle Open
SAA targets GOT2 to alleviate myocardial oxidative stress by regulating malate-aspartate NADH shuttle, thereby protecting against DIC. Our findings highlighted the therapeutic potential of activating GOT2 in mitigating DIC and the possibil…
View article: Overexpression of the alfalfa gene MsTIFY10a confers thrips resistance in Medicago truncatula
Overexpression of the alfalfa gene MsTIFY10a confers thrips resistance in Medicago truncatula Open
View article: Effect of Exogenous Hormones on the Growth of Alfalfa Seedlings under Phosphate Starvation Stress
Effect of Exogenous Hormones on the Growth of Alfalfa Seedlings under Phosphate Starvation Stress Open
Background: Alfalfa (Medicago sativa) is a high-quality legume forage. Phosphorus (P) is essential for plant productivity. Approximately half of global arable soils exhibit available-P deficiency, constraining plants growth and yield. This…
View article: Integrative analysis of programmed cell death pathways reveals prognostic biomarkers and immune infiltration signatures in coronary artery disease
Integrative analysis of programmed cell death pathways reveals prognostic biomarkers and immune infiltration signatures in coronary artery disease Open
The study highlights the importance of PCD pathways in CAD and the prognostic value of the PCDscore, offering a comprehensive tool for personalized treatment strategies.
View article: Overexpression MsJAR1 gene increased lateral branches and plant height in alfalfa (Medicago sativa L.)
Overexpression MsJAR1 gene increased lateral branches and plant height in alfalfa (Medicago sativa L.) Open
View article: Exogenous Methyl Jasmonate Mediated Physiological and Transcriptomic Network Improves Thrips tolerance in alfalfa (Medicago Sativa. L)
Exogenous Methyl Jasmonate Mediated Physiological and Transcriptomic Network Improves Thrips tolerance in alfalfa (Medicago Sativa. L) Open
Exogenous methyl jasmonate is widely acknowledged for its role in triggering plants' defense systems against pest invasions. Nonetheless, there has been a dearth of research exploring the elicitation of defense mechanisms by jasmonic acid …
View article: Genome-wide investigation of the TIFY transcription factors in alfalfa (Medicago sativa L.): identification, analysis, and expression
Genome-wide investigation of the TIFY transcription factors in alfalfa (Medicago sativa L.): identification, analysis, and expression Open
View article: Constituent analysis, laxative activity, and toxicological evaluation of methanol extract of noni fruit (Morinda citrifolia L., Rubiaceae)
Constituent analysis, laxative activity, and toxicological evaluation of methanol extract of noni fruit (Morinda citrifolia L., Rubiaceae) Open
Noni fruits have gained considerable popularity as dietary supplements. However, the major constituents, the laxative activity, and the toxicity of Noni fruit remains still unknown. The purpose of the present study was, therefore, to analy…
View article: Natural carrier-free self-assembled diterpene nanoparticles with its efficient anti-inflammation through the inhibition of NF-κB pathway for accelerated wound healing
Natural carrier-free self-assembled diterpene nanoparticles with its efficient anti-inflammation through the inhibition of NF-κB pathway for accelerated wound healing Open
Nanoscience has set off a wave in biomedicine to improve the performance of drugs in recent years, but additional materials are usually required for supramolecular nanoconstruction, undoubtedly increasing the health risks. Herein, we disco…
View article: MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension Open
Background. Pulmonary arterial hypertension (PAH) usually causes right ventricular dysfunction, which is closely related to cardiac fibrosis. But cardiac fibrosis mechanism remains unclear. Our purpose was to explore microRNA-325-3p (miR-3…
View article: Characteristics and Diversity of Endophytic Bacteria in Endangered Chinese Herb <i>Glehnia littoralis</i> Based on Illumina Sequencing
Characteristics and Diversity of Endophytic Bacteria in Endangered Chinese Herb <i>Glehnia littoralis</i> Based on Illumina Sequencing Open
Glehnia littoralis is an endangered medicinal plant growing in the coastal ecological environment and plays an important role in coastal ecosystems. The endophytes in the plant have a significant role in promoting plant growth and enhancin…
View article: The complete chloroplast genome sequence of <i>Amentotaxus yunnanensis</i> (Taxaceae)
The complete chloroplast genome sequence of <i>Amentotaxus yunnanensis</i> (Taxaceae) Open
The complete chloroplast genome sequence of Amentotaxus yunnanensis has been defined in this study. The genome is 138,604 bp in length and one of the large inverted repeats found till date. The overall GC content of the genome is 35…
View article: Hepatoprotective Effect of Aqueous Extract from the Seeds of Orychophragmus violaceus against Liver Injury in Mice and HepG2 Cells
Hepatoprotective Effect of Aqueous Extract from the Seeds of Orychophragmus violaceus against Liver Injury in Mice and HepG2 Cells Open
Orychophragmus violaceus (O. violaceus) is a kind of edible wild herb in north China and its seeds have medical potential, however, the effect of O. violaceus seeds on liver injury and the mechanism of action remains poorly understood. Thu…
View article: Hepatoprotective Effect of Carboxymethyl Pachyman in Fluorouracil-Treated CT26-Bearing Mice
Hepatoprotective Effect of Carboxymethyl Pachyman in Fluorouracil-Treated CT26-Bearing Mice Open
5-Fluorouracil (5-FU) is the chemotherapeutic agent of first choice for the treatment ofcolorectal cancer, however, treatment-related liver toxicity remains a major concern. Thereby, it is desirable to search for novel therapeutic approach…
View article: Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways
Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways Open
View article: Correction: Aqueous extract of Cordyceps sinensis potentiates the antitumor effect of DDP and attenuates therapy-associated toxicity in non-small cell lung cancer via IκBα/NFκB and AKT/MMP2/MMP9 pathways
Correction: Aqueous extract of Cordyceps sinensis potentiates the antitumor effect of DDP and attenuates therapy-associated toxicity in non-small cell lung cancer via IκBα/NFκB and AKT/MMP2/MMP9 pathways Open
Correction for ‘Aqueous extract of Cordyceps sinensis potentiates the antitumor effect of DDP and attenuates therapy-associated toxicity in non-small cell lung cancer via IκBα/NFκB and AKT/MMP2/MMP9 pathways’ by Xiaowei Huo et al., RSC Adv…
View article: Aqueous extract of Cordyceps sinensis potentiates the antitumor effect of DDP and attenuates therapy-associated toxicity in non-small cell lung cancer via IκBα/NFκB and AKT/MMP2/MMP9 pathways
Aqueous extract of Cordyceps sinensis potentiates the antitumor effect of DDP and attenuates therapy-associated toxicity in non-small cell lung cancer via IκBα/NFκB and AKT/MMP2/MMP9 pathways Open
Cordyceps sinensisis reported as an invigorant with pleiotropic biological effects that has potential for tumor therapy.
View article: Flavonoids Extracted from Licorice Prevents Colitis-Associated Carcinogenesis in AOM/DSS Mouse Model
Flavonoids Extracted from Licorice Prevents Colitis-Associated Carcinogenesis in AOM/DSS Mouse Model Open
Inflammatory bowel disease (IBD) is generally considered as a major risk factor in the progression of colitis-associated carcinogenesis (CAC). Thus, it is well accepted that ameliorating inflammation creates a potential to achieve an inhib…
View article: Antiinflammatory and Analgesic Activities of Ethanol Extract and Isolated Compounds from <i>Millettia pulchra</i>
Antiinflammatory and Analgesic Activities of Ethanol Extract and Isolated Compounds from <i>Millettia pulchra</i> Open
The plant Millettia pulchra was commonly used in folk medicine for the management of inflammation. However, there was no scientific rationale for these effects and the mechanism of action remained incompletely understood. The present study…