Xiaowei Huo
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View article: Predictive model development for left atrial remodeling in hypertrophic cardiomyopathy
Predictive model development for left atrial remodeling in hypertrophic cardiomyopathy Open
Left atrial structural remodeling is closely linked with the prognosis of patients with hypertrophic cardiomyopathy (HCM). This study aimed to evaluate the clinical characteristics and risk factors associated with left atrial remodeling in…
View article: Effects of SB939 are mediated by STAT3 to inhibit breast cancer cell metastasis‑related genes
Effects of SB939 are mediated by STAT3 to inhibit breast cancer cell metastasis‑related genes Open
The histone deacetylase inhibitor pracinostat (SB939) may inhibit metastasis of triple-negative breast cancer by downregulating fibronectin (FN1) expression through the STAT3 signaling pathway. SB939 exhibits low cytotoxicity and is a pote…
View article: The Development of a Nomogram Predictive Model for Intracardiac Thrombosis Risk: A Study Based on Risk Factors in Patients with Acute Myocardial Infarction
The Development of a Nomogram Predictive Model for Intracardiac Thrombosis Risk: A Study Based on Risk Factors in Patients with Acute Myocardial Infarction Open
Background/Objectives: Intracardiac thrombosis (ICT) is a serious complication in acute myocardial infarction (AMI) patients. This study aimed to identify potential risk factors of ICT in AMI patients, providing valuable insights for clini…
View article: Identifying the Characteristics and Implications of Post-Earthquake Debris Flow Events Based on Multi-Source Remote Sensing Images
Identifying the Characteristics and Implications of Post-Earthquake Debris Flow Events Based on Multi-Source Remote Sensing Images Open
Strong earthquakes often bring amounts of loose material, disrupting the balance of material transportation within a watershed and severely impacting the restoration of the ecological environment and human safety downstream. Therefore, it …
View article: Analysis of codon usage patterns in Bupleurum falcatum chloroplast genome
Analysis of codon usage patterns in Bupleurum falcatum chloroplast genome Open
The cp genome of B. falcatum has been characterized and the codon usage bias in B. falcatum cp genome is influenced by natural selection, mutation pressure and nucleotide composition. The results will provide much more barcode information …
View article: Detection and Molecular Characterization of Porcine Parvovirus 7 in Eastern Inner Mongolia Autonomous Region, China
Detection and Molecular Characterization of Porcine Parvovirus 7 in Eastern Inner Mongolia Autonomous Region, China Open
Porcine parvoviruses (PPV) and porcine circoviruses type 2 (PCV2) are widespread in the pig population. Recently, it was suggested that PPV7 may stimulate PCV2 and PCV3 replication. The present study aimed to make detection and molecular c…
View article: Co-assemblies based on natural Hemslecin A and β-sitosterol as a new sight for synergistic anti-gastric cancer efficacy in TCM
Co-assemblies based on natural Hemslecin A and β-sitosterol as a new sight for synergistic anti-gastric cancer efficacy in TCM Open
The curative effect of traditional Chinese medicine (TCM) is definite, but the material basis of TCM is not clear enough, or some known natural small molecules (NSMs) perform favorable pharmacological activities, however, the functioning m…
View article: Prediction and Analysis of miRNA Targets in Poplar in Response to the Infection of <i>Lonsdalea quercina</i> subsp <i>Populi</i>
Prediction and Analysis of miRNA Targets in Poplar in Response to the Infection of <i>Lonsdalea quercina</i> subsp <i>Populi</i> Open
Euramerican poplar bacterial canker disease caused by Lonsdalea quercina subsp. Populi is one of the stem diseases and seriously harmful to the growth and survival of poplar. MiRNAs play crucial roles in the regulation of the stress re…
View article: Metabolomics and Transcriptomics Integration of Early Response of Populus tomentosa to Reduced Nitrogen Availability
Metabolomics and Transcriptomics Integration of Early Response of Populus tomentosa to Reduced Nitrogen Availability Open
Nitrogen (N) is one of the most crucial elements for plant growth and development. However, little is known about the metabolic regulation of trees under conditions of N deficiency. In this investigation, gas chromatography-mass spectromet…
View article: Analysis of synonymous codon usage of transcriptome database in<i>Rheum palmatum</i>
Analysis of synonymous codon usage of transcriptome database in<i>Rheum palmatum</i> Open
Background Rheum palmatum is an endangered and important medicinal plant in Asian countries, especially in China. However, there is little knowledge about the codon usage bias for R. palmatum CDSs. In this project, codon usage bias was det…
View article: Hepatoprotective effect of different combinations of 18α-and 18β-Glycyrrhizic acid against CCl4-induced liver injury in rats
Hepatoprotective effect of different combinations of 18α-and 18β-Glycyrrhizic acid against CCl4-induced liver injury in rats Open
The purpose of the current study was to evaluate the optimal compatibility proportion of 18α-Glycyrrhizic acid (18α-GA) and 18β-Glycyrrhizic acid (18β-GA) against carbon tetrachloride (CCl4)-induced hepatic damage in rats, and further expl…
View article: Polyhydroxy cucurbitane triterpenes from Hemsleya penxianensis tubers
Polyhydroxy cucurbitane triterpenes from Hemsleya penxianensis tubers Open
Ten new cucurbitane triterpenoids, hemsleyacins A–J ( 1 – 10 ), together with three known cucurbitane triterpenoids, dihydrocucurbitacin F ( 11 ), scandenogenin D ( 12 ), and jinfushanencin F ( 13 ), were separated from ethanolic tuber ext…
View article: The complete chloroplast genome sequence of <i>Rheum tanguticum</i>, an endangered Chinese medicinal plant (<i>Polygonaceae</i>)
The complete chloroplast genome sequence of <i>Rheum tanguticum</i>, an endangered Chinese medicinal plant (<i>Polygonaceae</i>) Open
Rheum tanguticum is a valuable medicinal plant endemic to the Qinghai-Tibetan Plateau. It has been listed classified under the IUCN Red List categories of Vulnerable due to the low reproductive rate and heavy exploitation. In this study, t…
View article: Optimal ratio of 18α‑ and 18β‑glycyrrhizic acid for preventing alcoholic hepatitis in rats
Optimal ratio of 18α‑ and 18β‑glycyrrhizic acid for preventing alcoholic hepatitis in rats Open
The glycyrrhizic acid (GA) epimers 18α- and 18β-GA exert anti-inflammatory and hepatoprotective activities, which may help to protect against alcoholic liver disease, particularly alcoholic hepatitis (AH). The aim of the present study was …
View article: Paraoxonase 1 gene (Q192R) polymorphism confers susceptibility to coronary artery disease in type 2 diabetes patients: Evidence from case-control studies
Paraoxonase 1 gene (Q192R) polymorphism confers susceptibility to coronary artery disease in type 2 diabetes patients: Evidence from case-control studies Open
Numerous published studies have investigated the relationship between the paraoxonase 1 (PON1) gene Q192R (rs662) polymorphism and the risk of coronary artery disease (CAD) in type 2 diabetes mellitus (T2DM) patients. However, the results …
View article: RETRACTED: Huo et al. Protective Effect of Glycyrrhizic Acid on Alcoholic Liver Injury in Rats by Modulating Lipid Metabolism. Molecules 2018, 23, 1623
RETRACTED: Huo et al. Protective Effect of Glycyrrhizic Acid on Alcoholic Liver Injury in Rats by Modulating Lipid Metabolism. Molecules 2018, 23, 1623 Open
As the authors of the title paper [...]
View article: RETRACTED: Protective Effect of Glycyrrhizic Acid on Alcoholic Liver Injury in Rats by Modulating Lipid Metabolism
RETRACTED: Protective Effect of Glycyrrhizic Acid on Alcoholic Liver Injury in Rats by Modulating Lipid Metabolism Open
Glycyrrhhizic acid (GA), including 18α-glycyrrhizic acid (18α-GA) and 18β-glycyrrhizic acid (18β-GA), is the main active ingredient of licorice. GA is generally considered an effective pharmacological strategy protecting against hepatic di…
View article: Characterization of the complete chloroplast genome of the <i>Camellia nitidissima</i>, an endangered and medicinally important tree species endemic to Southwest China
Characterization of the complete chloroplast genome of the <i>Camellia nitidissima</i>, an endangered and medicinally important tree species endemic to Southwest China Open
The Camellia nitidissima is an endangered tree species native to Southwest China with high economic and medicinal values. Genetic information of C. nitidissima would provide good knowledge for the conservation of this wild resource. In thi…
View article: Promoting Public Participation in Post-Disaster Construction through Wechat Platform
Promoting Public Participation in Post-Disaster Construction through Wechat Platform Open
Purpose - How could memory, heritage and post-disaster construction integrated in practice? The purpose of this paper is to introduce our approach in public participation of reconstruction plan, after a raging fire destroyed part of the hi…