Xiaowu Wang
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View article: Population genomic insights into the domestication of <i>Brassica juncea</i> var. <i>tumida</i>
Population genomic insights into the domestication of <i>Brassica juncea</i> var. <i>tumida</i> Open
Brassica juncea var. tumida, commonly known as Zha Cai, is a pickled stem mustard widely cultivated in southern China. Its most distinctive trait is the swollen stem, which serves as the primary economic organ for harvest. However, the ori…
View article: Conserved sphingolipid metabolism under transcriptomic diversity: a prognostic and therapeutic target in triple-negative breast cancer
Conserved sphingolipid metabolism under transcriptomic diversity: a prognostic and therapeutic target in triple-negative breast cancer Open
View article: Clinical Utility of Monocyte-to-Lymphocyte Ratio and Prognostic Nutritional Index in Diagnosing Smear-Negative Pulmonary Tuberculosis with Negative IGRA Results
Clinical Utility of Monocyte-to-Lymphocyte Ratio and Prognostic Nutritional Index in Diagnosing Smear-Negative Pulmonary Tuberculosis with Negative IGRA Results Open
MLR, PNI and their combination offer moderate diagnostic value for SN-PTB when the IGRA result is negative; the combined MLR+PNI index performs better than either marker alone. However, these findings should be interpreted with caution due…
View article: Determination of HSS Model Parameters for Soft Clays in Hangzhou: Statistical Analysis and Engineering Validation
Determination of HSS Model Parameters for Soft Clays in Hangzhou: Statistical Analysis and Engineering Validation Open
The hardening soil model with small-strain stiffness (HSS model), capturing nonlinear stiffness of soils at small strains, offers advantages for deformation analysis of tunnels or deep excavations in soft clay areas such as Hangzhou City. …
View article: Comparative transcriptomic analysis of Chinese cabbage’s defense responses to Alternaria brassicae
Comparative transcriptomic analysis of Chinese cabbage’s defense responses to Alternaria brassicae Open
Black spot, a fungal disease caused by Alternaria brassicae infection, inflicts severe damage on Chinese cabbage. Through comparative transcriptomic analysis, this study investigated the molecular mechanisms underlying Chinese cabbage’s de…
View article: Identification of BoFLC2 as a major gene controlling flowering time in cabbage (Brassica oleracea var. capitata)
Identification of BoFLC2 as a major gene controlling flowering time in cabbage (Brassica oleracea var. capitata) Open
View article: Brassica diversity through the lens of polyploidy: genomic evolution, introgression, and homoeologous exchange
Brassica diversity through the lens of polyploidy: genomic evolution, introgression, and homoeologous exchange Open
Polyploidy, or whole-genome duplication, is an important evolutionary process that has shaped the genomes and traits of many plants, including numerous important crops. The Brassica genus, which includes diverse vegetables and oilseeds, is…
View article: Schaalia turicensis endometritis in a diabetic patient: MALDI-TOF MS overcomes diagnostic barriers in a non–IUD-associated case
Schaalia turicensis endometritis in a diabetic patient: MALDI-TOF MS overcomes diagnostic barriers in a non–IUD-associated case Open
Schaalia (Formerly Actinomyces) turicensis is a single-cell prokaryotic microorganism and a common component of the normal human oral flora. If it enters other parts and causes infection, it may lead to actinomycosis. We present the case o…
View article: A complete telomere-to-telomere assembly of the Spinacia oleracea genome reveals Y chromosome evolution and centromere landscape
A complete telomere-to-telomere assembly of the Spinacia oleracea genome reveals Y chromosome evolution and centromere landscape Open
View article: <scp>MAP2K2</scp> Knockdown Suppresses Phenotypic Transformation of Vascular Smooth Muscle Cells in Aortic Dissection by Inactivating the <scp>JAK</scp> / <scp>STAT</scp> Signaling Pathway
<span>MAP2K2</span> Knockdown Suppresses Phenotypic Transformation of Vascular Smooth Muscle Cells in Aortic Dissection by Inactivating the <span>JAK</span> / <span>STAT</span> Signaling Pathway Open
Aortic dissection (AD) is a severe aortic disease characterized by high morbidity and mortality. However, the primary treatments for AD possess limited efficacy. The role and specific mechanisms of mitogen‐activated protein kinase kinase 2…
View article: Disease spectrum of patients with hospital-acquired multidrug-resistant organism infections in the intensive care unit: a retrospective study
Disease spectrum of patients with hospital-acquired multidrug-resistant organism infections in the intensive care unit: a retrospective study Open
Objective To understand the infection status and disease spectrum distribution of patients with hospital-acquired Multidrug-resistant Organism (MDRO) Infections in an intensive care unit (ICU) before, during, and after the Coronavirus Dise…
View article: Multigeneration Sublethal Chlorantraniliprole Treatment Disrupts Nutritional Metabolism and Inhibits Growth, Development, and Reproduction of Phthorimaea absoluta
Multigeneration Sublethal Chlorantraniliprole Treatment Disrupts Nutritional Metabolism and Inhibits Growth, Development, and Reproduction of Phthorimaea absoluta Open
Phthorimaea absoluta, an important pest of tomato crops, has reportedly developed high levels of resistance to the insecticide chlorantraniliprole, which has a unique mode of action and high efficacy. This study evaluated the sustained mul…
View article: Effects of Dioscorea oppositifolia L. on growth performance, biochemical indicators, immunity, and intestinal health of weaned piglets
Effects of Dioscorea oppositifolia L. on growth performance, biochemical indicators, immunity, and intestinal health of weaned piglets Open
Introduction Weaning stress syndrome in piglets seriously endangers the healthy development of the breeding industry. Dioscorea oppositifolia L. (Chinese yam, YAM) has activities such as boosting immunity and regulating gastrointestinal fu…
View article: Correction: Integrating network pharmacology, molecular docking and experimental verification to explore the therapeutic effect and potential mechanism of nomilin against triple-negative breast cancer
Correction: Integrating network pharmacology, molecular docking and experimental verification to explore the therapeutic effect and potential mechanism of nomilin against triple-negative breast cancer Open
View article: Exploring Novel Therapeutic Targets in Breast Cancer via Comprehensive Omics Profiling and Experimental Verification
Exploring Novel Therapeutic Targets in Breast Cancer via Comprehensive Omics Profiling and Experimental Verification Open
Background: Breast cancer is the leading cause of cancer-related deaths among women worldwide. Deciphering the molecular mechanisms of breast cancer is crucial for developing targeted therapeutic approaches. Methods: This study analyzed ge…
View article: Causal association of breast cancer with immune cells: new evidence from bi-directional Mendelian randomization using GWAS summary statistics
Causal association of breast cancer with immune cells: new evidence from bi-directional Mendelian randomization using GWAS summary statistics Open
This study utilized genetic approaches to establish a causal relationship between immune cell traits and breast cancer. These findings offer potential novel targets for diagnosing and treating breast cancer.
View article: <i>Ultrabithorax</i> regulates <i>Leptinotarsa decemlineata</i> wing development along with insulin and <i>ecdysteroid</i> signaling pathways
<i>Ultrabithorax</i> regulates <i>Leptinotarsa decemlineata</i> wing development along with insulin and <i>ecdysteroid</i> signaling pathways Open
Leptinotarsa decemlineata (Say) (Colorado potato beetle, CPB) is a notorious pest of potatoes. Its hardened forewings, known as elytra, protect the hindwings and the abdomen against enemies and chemical pesticides. Ubx plays a crucial role…
View article: Developmental landscape and asymmetric gene expression in the leaf vasculature of <i>Brassica rapa</i> revealed by single-cell transcriptome
Developmental landscape and asymmetric gene expression in the leaf vasculature of <i>Brassica rapa</i> revealed by single-cell transcriptome Open
Leaf vasculature not only acts as a channel for nutrients and signaling information but also influences leaf morphology. It consists of several distinct cell types with specialized functions. Cell type-specific characterizations based on s…
View article: PANoptosis-related genes in the prognosis and immune landscape of hepatocellular carcinoma
PANoptosis-related genes in the prognosis and immune landscape of hepatocellular carcinoma Open
View article: Effects of Chlorantraniliprole on Development and Biochemical Parameters of Phthorimaea Absoluta (Meyrick)
Effects of Chlorantraniliprole on Development and Biochemical Parameters of Phthorimaea Absoluta (Meyrick) Open
View article: Author Correction: Development and validation of a prognostic signature of breast cancer based on drug absorption, distribution, metabolism and excretion (ADME)-related genes
Author Correction: Development and validation of a prognostic signature of breast cancer based on drug absorption, distribution, metabolism and excretion (ADME)-related genes Open
View article: Effects of targeted care using a risk warning model on burn site infection
Effects of targeted care using a risk warning model on burn site infection Open
Introduction: Prevention and control of wound infection in burn patients is critical. This study aimed to establish an infection risk warning model based on the clinical characteristics of burn patients, by formulating targeted care progra…
View article: The association between cardiovascular health and obstructive sleep apnea symptoms: findings from NHANES
The association between cardiovascular health and obstructive sleep apnea symptoms: findings from NHANES Open
Objective To investigate the association between cardiovascular health (CVH) and obstructive sleep apnea (OSA) within the U.S. population. Methods This study enrolled 12,540 participants aged 20 years and older from the 2007–2008 and 2015–…
View article: N7-methylguanosine-based signature for tumor subtyping and prognosis and immunotherapy prediction of stomach cancer
N7-methylguanosine-based signature for tumor subtyping and prognosis and immunotherapy prediction of stomach cancer Open
Background Gastric cancer is an aggressive disease with complex tumor heterogeneity, influenced by genomic, transcriptomic, and translational processes. N7-methylguanylate (m7G) modification is a potential factor in tumor heterogeneity, bu…
View article: Uremic syndrome with newly diagnosed HIV infection: reflections on a particular case
Uremic syndrome with newly diagnosed HIV infection: reflections on a particular case Open
Introduction: Diagnosis with Western blot test (WB) may not provide clear results for certain patients, including those who are not infected with human immunodeficiency virus (HIV) but produce non-specific reactions, individuals in the HIV…
View article: Integrating network pharmacology, molecular docking and experimental verification to explore the therapeutic effect and potential mechanism of nomilin against triple-negative breast cancer
Integrating network pharmacology, molecular docking and experimental verification to explore the therapeutic effect and potential mechanism of nomilin against triple-negative breast cancer Open
Background Nomilin is a limonoid compound known for its multiple biological activities, but its role in triple negative breast cancer (TNBC) remains unclear. This study aims to uncover the potential therapeutic effect of nomilin on TNBC an…
View article: Development and validation of a prognostic signature of breast cancer based on drug absorption, distribution, metabolism and excretion (ADME)-related genes
Development and validation of a prognostic signature of breast cancer based on drug absorption, distribution, metabolism and excretion (ADME)-related genes Open
View article: Identification of a novel histone acetylation-related long non-coding RNA model combined with qRT-PCR experiments for prognosis and therapy in gastric cancer
Identification of a novel histone acetylation-related long non-coding RNA model combined with qRT-PCR experiments for prognosis and therapy in gastric cancer Open
View article: ELANE is a promising prognostic biomarker that mediates pyroptosis in gastric cancer
ELANE is a promising prognostic biomarker that mediates pyroptosis in gastric cancer Open
High ELANE expression is related to poor survival and prognosis of patients with GC. It participates in pyroptosis and immune infiltration in GC. Therefore, ELANE is a promising prognostic biomarker for pyroptosis in GC.
View article: Erratum to “Characterization of a predictive signature for tumor microenvironment and immunotherapy response in hepatocellular carcinoma involving neutrophil extracellular traps” [Heliyon Volume 10, issue 10, May 2024, article e30827]
Erratum to “Characterization of a predictive signature for tumor microenvironment and immunotherapy response in hepatocellular carcinoma involving neutrophil extracellular traps” [Heliyon Volume 10, issue 10, May 2024, article e30827] Open
[This corrects the article DOI: 10.1016/j.heliyon.2024.e30827.].