Xiaoxin Wu
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View article: InteractiveOmni: A Unified Omni-modal Model for Audio-Visual Multi-turn Dialogue
InteractiveOmni: A Unified Omni-modal Model for Audio-Visual Multi-turn Dialogue Open
We introduce InteractiveOmni, a unified and open-source omni-modal large language model for audio-visual multi-turn interaction, ranging from 4B to 8B parameters, designed to lead the field of lightweight models by offering comprehensive o…
View article: Impact of topical application of Natrii sulfas on recovery and quality of life in patients with severe peristomal edema following enterostomy
Impact of topical application of Natrii sulfas on recovery and quality of life in patients with severe peristomal edema following enterostomy Open
View article: Advances in the extracellular vesicles treatment of alopecia
Advances in the extracellular vesicles treatment of alopecia Open
Significant progress has been made in understanding the preparation, mechanisms, and early clinical applications of EVs. However, further research is needed to optimize key factors, such as dosing, cell sources, and administration frequenc…
View article: Unraveling Genetic Causality Between Type 2 Diabetes Mellitus and Hemiplegia Based on Mendelian Randomization
Unraveling Genetic Causality Between Type 2 Diabetes Mellitus and Hemiplegia Based on Mendelian Randomization Open
This study shows a causal relationship between T2DM and hemiplegia, indicating that T2DM increases the risk of hemiplegia, which may provide guidance for additional hemiplegia screening in T2DM patients.
View article: Dysfunction of monocyte in the development of HBV-ACLF: Immune activation or immune suppression?
Dysfunction of monocyte in the development of HBV-ACLF: Immune activation or immune suppression? Open
View article: Role of cytomegalovirus in glioblastoma development: promoter or culprit?
Role of cytomegalovirus in glioblastoma development: promoter or culprit? Open
Glioblastoma is the most common primary malignant tumor of the central nervous system, with a median survival of less than two years. While the etiology of glioblastoma is unclear, viral infection has emerged as a potential contributing fa…
View article: Causal relationships between alterations in shear stress-related genes and aneurysmal subarachnoid hemorrhage
Causal relationships between alterations in shear stress-related genes and aneurysmal subarachnoid hemorrhage Open
View article: Predictive Model for In-Hospital Death in Older Patients with Type 2 Diabetes Mellitus: A Multicenter Retrospective Study in Southwest China
Predictive Model for In-Hospital Death in Older Patients with Type 2 Diabetes Mellitus: A Multicenter Retrospective Study in Southwest China Open
The prediction model developed in this study demonstrated robust discrimination, calibration, and clinical utility. It can assist healthcare professionals in identifying high-risk older patients with T2DM, facilitating early prevention, de…
View article: Potential Roles of Serum Exosomal CD155 and its Impact on NK Cell Immunosuppression in Hepatocellular Carcinoma
Potential Roles of Serum Exosomal CD155 and its Impact on NK Cell Immunosuppression in Hepatocellular Carcinoma Open
These results disclose exo-CD155 shows promise for serving as a biomarker for HCC, especially in early-stage patients or those with normal AFP/AFP-L3 levels. Moreover, serum exosomes from HCC patients suppress NK cell immune functions thro…
View article: Evolving therapeutic strategies for severe fever with thrombocytopenia syndrome: from past to future
Evolving therapeutic strategies for severe fever with thrombocytopenia syndrome: from past to future Open
Severe fever with thrombocytopenia syndrome (SFTS) is a hemorrhagic fever caused by Bandavirus dabieense . SFTS was first identified in China in 2009 and has been reported since then in neighboring countries and regions. The clinical manif…
View article: Severe fever with thrombocytopenia syndrome complicated with aspergillus endocarditis and multiple organ infarctions after glucocorticoid treatment in an immunocompetent man: a case report
Severe fever with thrombocytopenia syndrome complicated with aspergillus endocarditis and multiple organ infarctions after glucocorticoid treatment in an immunocompetent man: a case report Open
View article: Image Restoration Model Compression via Mamba-oriented Heterogeneous Knowledge Distillation
Image Restoration Model Compression via Mamba-oriented Heterogeneous Knowledge Distillation Open
View article: Correction: Longitudinal dynamic single-cell mass cytometry analysis of peripheral blood mononuclear cells in COVID-19 patients within 6 months after viral RNA clearance
Correction: Longitudinal dynamic single-cell mass cytometry analysis of peripheral blood mononuclear cells in COVID-19 patients within 6 months after viral RNA clearance Open
View article: Longitudinal dynamic single-cell mass cytometry analysis of peripheral blood mononuclear cells in COVID-19 patients within 6 months after viral RNA clearance
Longitudinal dynamic single-cell mass cytometry analysis of peripheral blood mononuclear cells in COVID-19 patients within 6 months after viral RNA clearance Open
This study investigates the longitudinal dynamic changes in immune cells in COVID-19 patients over an extended period after recovery, as well as the interplay between immune cells and antibodies. Leveraging single-cell mass spectrometry, w…
View article: Host proteins interact with viral elements and affect the life cycle of highly pathogenic avian influenza A virus H7N9
Host proteins interact with viral elements and affect the life cycle of highly pathogenic avian influenza A virus H7N9 Open
Host-virus interactions can significantly impact the viral life cycle and pathogenesis; however, our understanding of the specific host factors involved in highly pathogenic avian influenza A virus H7N9 (HPAI H7N9) infection is currently r…
View article: The 90‐Day Survival Threshold: A Pivotal Determinant of Long‐Term Prognosis in HBV‐ACLF Patients – Insights from a Prospective Longitudinal Cohort Study
The 90‐Day Survival Threshold: A Pivotal Determinant of Long‐Term Prognosis in HBV‐ACLF Patients – Insights from a Prospective Longitudinal Cohort Study Open
This work aims to explore the long‐term prognosis of hepatitis B virus‐related acute‐on‐chronic liver failure (HBV‐ACLF). In this prospective study, eligible inpatients with HBV‐ACLF are enrolled and followed up from December 2012 to Febru…
View article: Treatment strategy for erythropoietic protoporphyria accompanied by severe abdominal pain and liver injury
Treatment strategy for erythropoietic protoporphyria accompanied by severe abdominal pain and liver injury Open
Erythropoietic protoporphyria (EPP) is a genetic disease caused by a lack of the enzyme ferrochelatase (FECH) in the heme biosynthesis pathway due to genetic defects. FECH deficiency is caused by a deleterious FECH variant in transposition…
View article: Mapping trends and hotspots in research on global influenza vaccine hesitancy: A bibliometric analysis
Mapping trends and hotspots in research on global influenza vaccine hesitancy: A bibliometric analysis Open
Background and Aims Influenza is one of the most widespread respiratory infections and poses a huge burden on health care worldwide. Vaccination is key to preventing and controlling influenza. Influenza vaccine hesitancy is an important re…
View article: Cellular Senescence in Acute Liver Injury: What Happens to the Young Liver?
Cellular Senescence in Acute Liver Injury: What Happens to the Young Liver? Open
Cellular senescence, characterized by irreversible cell cycle arrest, not only exists in age-related physiological states, but has been found to exist in various diseases. It plays a crucial role in both physiological and pathological proc…
View article: Impact of Crack Angle Variations on Stress Intensity Factors in Mixed-Mode Failure of Edge-Cracked Die Steels
Impact of Crack Angle Variations on Stress Intensity Factors in Mixed-Mode Failure of Edge-Cracked Die Steels Open
View article: Maternal and neonatal outcomes of twin pregnancies complicated by gestational diabetes mellitus
Maternal and neonatal outcomes of twin pregnancies complicated by gestational diabetes mellitus Open
View article: Development and validation of a risk prediction model for osteoporosis in elderly patients with type 2 diabetes mellitus: a retrospective and multicenter study
Development and validation of a risk prediction model for osteoporosis in elderly patients with type 2 diabetes mellitus: a retrospective and multicenter study Open
Background This study aimed to construct a risk prediction model to estimate the odds of osteoporosis (OP) in elderly patients with type 2 diabetes mellitus (T2DM) and evaluate its prediction efficiency. Methods This study included 21,070 …
View article: Longitudinal dynamic single-cell mass cytometry analysis of peripheral blood mononuclear cells in COVID-19 patients within 6 months after viral RNA clearance
Longitudinal dynamic single-cell mass cytometry analysis of peripheral blood mononuclear cells in COVID-19 patients within 6 months after viral RNA clearance Open
This study investigates the longitudinal dynamic changes in immune cells in COVID-19 patients over an extended period after recovery, as well as the interplay between immune cells and antibodies. Leveraging single-cell mass spectrometry, w…
View article: Clinical Data based XGBoost Algorithm for infection risk prediction of patients with decompensated cirrhosis: a 10-year (2012–2021) Multicenter Retrospective Case-control study
Clinical Data based XGBoost Algorithm for infection risk prediction of patients with decompensated cirrhosis: a 10-year (2012–2021) Multicenter Retrospective Case-control study Open
Objectives To appraise effective predictors for infection in patients with decompensated cirrhosis (DC) by using XGBoost algorithm in a retrospective case-control study. Methods Clinical data were retrospectively collected from 6,648 patie…
View article: Bibliometric analysis of publication trends and topics of influenza‐related encephalopathy from 2000 to 2022
Bibliometric analysis of publication trends and topics of influenza‐related encephalopathy from 2000 to 2022 Open
Background Influenza‐related encephalopathy is a rapidly progressive encephalopathy that usually presents during the early phase of influenza infection and primarily manifests as central nervous system dysfunction. This study aimed to anal…
View article: <i>RNF213</i> loss-of-function promotes pathological angiogenesis in moyamoya disease via the Hippo pathway
<i>RNF213</i> loss-of-function promotes pathological angiogenesis in moyamoya disease via the Hippo pathway Open
Moyamoya disease is an uncommon cerebrovascular disorder characterized by steno-occlusive changes in the circle of Willis and abnormal vascular network development. Ring finger protein 213 (RNF213) has been identified as an important susce…
View article: OHCCPredictor: an online risk stratification model for predicting survival duration of older patients with hepatocellular carcinoma
OHCCPredictor: an online risk stratification model for predicting survival duration of older patients with hepatocellular carcinoma Open
View article: Severe acute hepatitis of unknown origin in children: Clinical issues of concern
Severe acute hepatitis of unknown origin in children: Clinical issues of concern Open
View article: A novel model for predicting prolonged stay of patients with type-2 diabetes mellitus: a 13-year (2010–2022) multicenter retrospective case–control study
A novel model for predicting prolonged stay of patients with type-2 diabetes mellitus: a 13-year (2010–2022) multicenter retrospective case–control study Open
Background Length of stay (LOS) is an important metric for evaluating the management of inpatients. This study aimed to explore the factors impacting the LOS of inpatients with type-2 diabetes mellitus (T2DM) and develop a predictive model…
View article: Rnf-213 knockout induces pericyte reduction and blood-brain barrier impairment in mouse
Rnf-213 knockout induces pericyte reduction and blood-brain barrier impairment in mouse Open
Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by progressive occlusion of the internal carotid artery and the formation of an abnormal compensatory capillary network at the base of the brain. Genomics studies iden…