Xiaoxing Mo
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View article: Plasma ceramide mediates the association of peripheral T cells with Alzheimer’s disease
Plasma ceramide mediates the association of peripheral T cells with Alzheimer’s disease Open
This study identifies CD4 EM and CD8 CM T cells as key drivers of AD-related neuroinflammation and uncovers a possible immunometabolic pathway linking CD4 EM, ceramide metabolism, and AD risk, suggesting potential targets for early diagnos…
View article: Bilberry extract ameliorates high-AGEs diet induced AD-like pathological changes through the modulation of gut microbiota
Bilberry extract ameliorates high-AGEs diet induced AD-like pathological changes through the modulation of gut microbiota Open
View article: Melatonin Mitigates Sarcopenic Obesity via Microbiota and Short‐Chain Fatty Acids: Evidence From Epidemiologic and In Vivo Studies
Melatonin Mitigates Sarcopenic Obesity via Microbiota and Short‐Chain Fatty Acids: Evidence From Epidemiologic and In Vivo Studies Open
Introduction Gut dysbiosis is closely related to the development of sarcopenic obesity (SO). Melatonin (MLT) regulates gut microbiota and promotes the production of short‐chain fatty acids (SCFAs). However, whether MLT affects SO through t…
View article: High-fat diet induces sarcopenic obesity in natural aging rats through the gut–trimethylamine N-oxide–muscle axis
High-fat diet induces sarcopenic obesity in natural aging rats through the gut–trimethylamine N-oxide–muscle axis Open
HFD leads to SO in natural aging rats, partially through the gut-microbiota-TMAO-muscle axis.
View article: Robust Backdoor Detection for Deep Learning via Topological Evolution Dynamics
Robust Backdoor Detection for Deep Learning via Topological Evolution Dynamics Open
A backdoor attack in deep learning inserts a hidden backdoor in the model to trigger malicious behavior upon specific input patterns. Existing detection approaches assume a metric space (for either the original inputs or their latent repre…
View article: Faecal microbiota transplantation from young rats attenuates age‐related sarcopenia revealed by multiomics analysis
Faecal microbiota transplantation from young rats attenuates age‐related sarcopenia revealed by multiomics analysis Open
Background Gut microbiota plays a key role in the development of sarcopenia via the ‘gut‐muscle’ axis, and probiotics‐based therapy might be a strategy for sarcopenia. Fecal microbiota transplantation from young donors (yFMT) has attracted…
View article: Backdoor Attack on Deep Neural Networks in Perception Domain
Backdoor Attack on Deep Neural Networks in Perception Domain Open
As deep neural networks (DNNs) are widely deployed in various applications, the security of pretrained DNNs is crucial since backdoors can be introduced through poisoned training. A backdoored DNN model works properly when benign inputs ar…
View article: Cyber Threat Intelligence Mining for Proactive Cybersecurity Defense: A Survey and New Perspectives
Cyber Threat Intelligence Mining for Proactive Cybersecurity Defense: A Survey and New Perspectives Open
Today's cyber attacks have become more severe and frequent, which calls for a new line of security defenses to protect against them. The dynamic nature of new-generation threats, which are evasive, resilient, and complex, makes traditional…
View article: Yeast beta-Glucan effects on gut microbiota for regulating insulin signaling system on alzheimer's disease
Yeast beta-Glucan effects on gut microbiota for regulating insulin signaling system on alzheimer's disease Open
Introduction: Alzheimer's disease (AD) is a progressive neurodegenerative disease for dementia in adults. The main pathological alterations are extracellular senile plaque deposits, intracellular neurofibrillary tangles and neuronal apopto…
View article: Procyanidins Extracted from Lotus Seedpod Ameliorate Amyloid‐<i>β</i>‐Induced Toxicity in Rat Pheochromocytoma Cells
Procyanidins Extracted from Lotus Seedpod Ameliorate Amyloid‐<i>β</i>‐Induced Toxicity in Rat Pheochromocytoma Cells Open
Alzheimer’s disease (AD) is a progressive neurodegenerative disease, which is characterized by extracellular senile plaque deposits, intracellular neurofibrillary tangles, and neuronal apoptosis. Amyloid‐ β (A β ) plays a critical role in …