Xiaoxu Jin
YOU?
Author Swipe
View article: Single‐Cell Genetic Mapping of Gasdermin Expression Across Immune‐Mediated Inflammatory Diseases
Single‐Cell Genetic Mapping of Gasdermin Expression Across Immune‐Mediated Inflammatory Diseases Open
The gasdermin ( GSDM ) family mediates pyroptosis and membrane pore formation, but the causal, cell‐type–specific roles of individual paralogues in immune‐mediated inflammatory diseases ( IMIDs ) remain poorly defined. We combined single‐c…
View article: Combining biomarkers to construct a novel predictive model for predicting preoperative lymph node metastasis in early gastric cancer
Combining biomarkers to construct a novel predictive model for predicting preoperative lymph node metastasis in early gastric cancer Open
Background Accurately identifying the status of lymph node metastasis (LNM) is crucial for determining the appropriate treatment strategy for early gastric cancer (EGC) patients. Methods Univariate and multivariate logistic regression anal…
View article: Application of a self-made liver suspension device in 3D laparoscopic non-anatomical resection of liver segment VI and VII tumors
Application of a self-made liver suspension device in 3D laparoscopic non-anatomical resection of liver segment VI and VII tumors Open
The self-designed liver suspension device enhances the safety and efficiency of 3D laparoscopic NAR resection for hepatic segment VI and VII tumors by minimizing operative trauma, reducing mechanical injury risks, and promoting postoperati…
View article: Identification and validation of serum MUC17 as a non‐invasive early warning biomarker for screening of gastric intraepithelial neoplasia
Identification and validation of serum MUC17 as a non‐invasive early warning biomarker for screening of gastric intraepithelial neoplasia Open
These findings suggest that plasma MUC17 levels hold substantial promise as a screening biomarker for individuals with GIN and EGC, effectively identifying high-risk groups that necessitate further gastroscopy.
View article: Case report: Single-cell RNA sequencing of PBMCs highlights monocyte gene expression alterations in a type A HBV-ACLF patient
Case report: Single-cell RNA sequencing of PBMCs highlights monocyte gene expression alterations in a type A HBV-ACLF patient Open
Hepatitis B Virus-related acute-on-chronic liver failure (HBV-ACLF) is a severe complication with high fatality rates. However, the underlying mechanisms are still elusive and require further investigation. In this report, we described a c…
View article: The application of self-made liver suspension device in 3D laparoscopic non-anatomical resection of liver VI and VII segments tumors
The application of self-made liver suspension device in 3D laparoscopic non-anatomical resection of liver VI and VII segments tumors Open
Objective: To investigate the effect of self-made liver suspension device in 3D laparoscopic non-anatomical resection of liver VI and VII segments tumors. Methods: The clinical data of 79 patients who underwent non-anatomical resection of …
View article: Development and validation of risk prediction model for bacterial infections in acute liver failure patients
Development and validation of risk prediction model for bacterial infections in acute liver failure patients Open
Infections significantly increase mortality in acute liver failure (ALF) patients, and there are no risk prediction models for early diagnosis and treatment of infections in ALF patients. This study aims to develop a risk prediction model …
View article: Identification of Immune Infiltrating Cell-Related Biomarkers in Early Gastric Cancer Progression
Identification of Immune Infiltrating Cell-Related Biomarkers in Early Gastric Cancer Progression Open
Objectives Gastric cancer (GC) is one of the most prevalent malignancies worldwide, and early detection is crucial for improving patient survival rates. We aimed to identify immune infiltrating cell-related biomarkers in early gastric canc…
View article: Transcription factor Krüppel‐like factor 4 upregulated G protein‐coupled receptor 30 alleviates intestinal inflammation and apoptosis, and protects intestinal integrity from intestinal ischemia–reperfusion injury
Transcription factor Krüppel‐like factor 4 upregulated G protein‐coupled receptor 30 alleviates intestinal inflammation and apoptosis, and protects intestinal integrity from intestinal ischemia–reperfusion injury Open
Introduction Intestinal ischemia/reperfusion (I/R) injury is a common clinical event occurring during multiple clinical pathological processes. Here, we designed this paper to discuss the role of G protein‐coupled receptor 30 (GPR30) playi…
View article: Rosmarinic Acid Protects Mice from Concanavalin A-Induced Hepatic Injury through AMPK Signaling
Rosmarinic Acid Protects Mice from Concanavalin A-Induced Hepatic Injury through AMPK Signaling Open
Rosmarinic acid (RA) is extensively utilized in herbal medicine in China. The AMP-activated protein kinase (AMPK) signaling can be activated by RA and inhibited by the synthetic, reversible AMP-competitive inhibitor, Compound C (CC). The o…
View article: Efficacy of CTPV for Diagnostic and Therapeutic Assessment: Comparison with Endoscopy in Cirrhotic Patients with Gastroesophageal Varices
Efficacy of CTPV for Diagnostic and Therapeutic Assessment: Comparison with Endoscopy in Cirrhotic Patients with Gastroesophageal Varices Open
Background and Aims . Computed tomography portal venography (CTPV) shows potential in detecting varices that need treatment and their drainage pathways. However, its agreement with endoscopy requires further study. We investigated the feas…