Xu Han
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View article: A miR-JL-5 inhibitor modulates the proliferation of Nosema ceranae in Apis cerana
A miR-JL-5 inhibitor modulates the proliferation of Nosema ceranae in Apis cerana Open
Background and aims Apis cerana is the native host of Nosema ceranae ( N. ceranae ). Previous studies reported that N. ceranae was more harmful to the new host ( Apis mellifera ) than the original host that had spread globally and become o…
View article: Peptide CyRL-QN15 alleviates UVB-induced skin aging by promoting the repair of barrier
Peptide CyRL-QN15 alleviates UVB-induced skin aging by promoting the repair of barrier Open
Skin photoaging, a process with substantial physical and psychological impacts, is also a recognized risk factor for skin cancer. Despite advancements in dermatological research, effective prevention and reversal of photoaging remain chall…
View article: UV‐Ozone Surface Modification to Suppress the Crosstalk in the Sb <sub>2</sub> Se <sub>3</sub> ‐Based Broadband Photodetector Array
UV‐Ozone Surface Modification to Suppress the Crosstalk in the Sb <sub>2</sub> Se <sub>3</sub> ‐Based Broadband Photodetector Array Open
As a promising material of photodetectors (PDs), antimony selenide (Sb 2 Se 3 ) and its heterostructure own the advantages of low cost, high absorption coefficient, and excellent optoelectrical properties. However, the imaging application …
View article: Modeling of underwater vehicle positioning accuracy assessment based on ultrashort baseline
Modeling of underwater vehicle positioning accuracy assessment based on ultrashort baseline Open
Considering the effects of complexity and uncertainty in underwater environments, solving the lower bound of the underwater vehicle positioning error variance is crucial for assessing positioning accuracy. To address the problem of nonline…
View article: Enhancing Fault Diagnosis in GWAC: A Monitoring System for Telescope Arrays
Enhancing Fault Diagnosis in GWAC: A Monitoring System for Telescope Arrays Open
The Ground-based Wide-Angle Cameras array (GWAC) necessitates the integration of over 100 hardware devices, more than 100 servers, and upwards of 2500 software modules, all synchronized within a 3-second imaging cycle. However, the complex…
View article: Long‐Term Creatine Supplementation Improves Cognitive and Hippocampal Structural Plasticity Impairments in a D‐Gal‐Induced Aging Model via Increasing CK‐BB Activity in the Brain
Long‐Term Creatine Supplementation Improves Cognitive and Hippocampal Structural Plasticity Impairments in a D‐Gal‐Induced Aging Model via Increasing CK‐BB Activity in the Brain Open
Creatine (Cr) is recognized for its role in enhancing cognitive functions through the phosphocreatine (pCr)–creatine kinase system involved in brain energy homeostasis. It is reversibly converted into pCr by creatine kinase (CK). A brain‐s…
View article: Immune regulation: a new strategy for traditional Chinese medicine-based treatment of granulomatous lobular mastitis
Immune regulation: a new strategy for traditional Chinese medicine-based treatment of granulomatous lobular mastitis Open
Granulomatous lobular mastitis (GLM) presents significant challenges, including high rates of morbidity, recurrence, and disability, ultimately impacting women’s health and quality of life. Local autoimmune imbalance involving dysregulated…
View article: Exosomal miR-129 and miR-342 derived from intermittent hypoxia-stimulated vascular smooth muscle cells inhibit the eIF2α/ATF4 axis from preventing calcified aortic valvular disease
Exosomal miR-129 and miR-342 derived from intermittent hypoxia-stimulated vascular smooth muscle cells inhibit the eIF2α/ATF4 axis from preventing calcified aortic valvular disease Open
This study aims to elucidate the role of miR-129/miR-342 loaded in exosomes derived from vascular smooth muscle cells (VSMCs) stimulated by intermittent hypoxia in calcified aortic valvular disease (CAVD). Bioinformatics analysis was condu…
View article: A dominant pathogenic MEFV mutation causes atypical pyrin-associated periodic syndromes
A dominant pathogenic MEFV mutation causes atypical pyrin-associated periodic syndromes Open
Pyrin, a protein encoded by the MEFV gene, plays a vital role in innate immunity by sensing modifications in Rho GTPase and assembling the pyrin inflammasome, which in turn activates downstream immune responses. We identified a novel and d…
View article: Prediction of the incidence of colorectal cancer by routine laboratory tests and anthropometric measurements about metabolism
Prediction of the incidence of colorectal cancer by routine laboratory tests and anthropometric measurements about metabolism Open
Objective To investigate the relationship between metabolic disorders and the morbidity of colorectal cancer (CRC) compared with colorectal adenoma (CRA) and non-neoplastic inpatients, especially to investigate which anthropometric measure…
View article: Broadband dispersion compensating ring-core fiber for orbital angular momentum modes
Broadband dispersion compensating ring-core fiber for orbital angular momentum modes Open
A well designed ring-core fiber can theoretically support numerous orbital angular momentum (OAM) modes with low crosstalk for space-division-multiplexing (SDM) data transmission, which is considered as a promising solution for overcoming …
View article: Prediction of the incidence of colorectal cancer by routine laboratory tests and anthropometric measurements about metabolism
Prediction of the incidence of colorectal cancer by routine laboratory tests and anthropometric measurements about metabolism Open
Objective To investigate the relationship between metabolic disorders and the morbidity of colorectal cancer (CRC) compared with colorectal adenoma (CRA) and non-neoplastic inpatients, especially to investigate which anthropometric measure…
View article: Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis
Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis Open
Sepsis is a disease characterized by multiple organ failure caused by immune hyperactivation and cytokine storms. Studies have shown that the incidence of sepsis in melanoma patients is substantially lower compared to the general populatio…
View article: Hybrid-Light-Source Stereolithography for Fabricating Macro-Objects With Micro-Textures
Hybrid-Light-Source Stereolithography for Fabricating Macro-Objects With Micro-Textures Open
Microscale surface structures are commonly found on macroscale bodies of natural creatures for their unique functions. However, it is difficult to fabricate such multi-scale geometry with conventional stereolithography processes that rely …
View article: Spatiotemporal Projection‐Based Additive Manufacturing: A Data‐Driven Image Planning Method for Subpixel Shifting in a Split Second
Spatiotemporal Projection‐Based Additive Manufacturing: A Data‐Driven Image Planning Method for Subpixel Shifting in a Split Second Open
Additive manufacturing (AM) is a digital manufacturing process that can directly convert a computer‐aided design model into a physical object in a layer‐by‐layer manner. Due to the additive and discrete nature of the digital manufacturing …
View article: Changes in lipid profiles and blood pressure in response to acute exposure to ambient PM2.5 and its carbonaceous compositions - results from the AIRLESS Study
Changes in lipid profiles and blood pressure in response to acute exposure to ambient PM2.5 and its carbonaceous compositions - results from the AIRLESS Study Open
Background Increasing evidence has shown ambient fine particles (PM2.5) as a key risk factor to cardiovascular and metabolic diseases. However, few human studies examined if the adverse effects were associated carbonaceous particles, the p…