Xiaoyan Pang
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View article: <i>Ficus pandurata</i> as a Functional Phytotherapeutic: Inhibiting <scp>JAK2</scp> / <scp>STAT3</scp> Signaling and Activating Mitochondrial Apoptosis in Hepatocellular Carcinoma
<i>Ficus pandurata</i> as a Functional Phytotherapeutic: Inhibiting <span>JAK2</span> / <span>STAT3</span> Signaling and Activating Mitochondrial Apoptosis in Hepatocellular Carcinoma Open
Chronic inflammation plays a key role in the development of hepatocellular carcinoma (HCC), one of the most prevalent and lethal forms of liver cancer. This study aimed to evaluate the anti‐HCC potential of the petroleum ether extract of F…
View article: Cardiac aging: Molecular mechanisms and therapeutic interventions
Cardiac aging: Molecular mechanisms and therapeutic interventions Open
Cardiac aging is a fundamental driver of cardiovascular diseases (CVDs), the leading cause of global mortality. While age is a non-modifiable risk factor, understanding its underlying molecular basis offers new avenues for therapeutic inte…
View article: Engineering an epoxy tanning agent via facile functionalization of sucrose with silane coupling agent for sustainable leather production
Engineering an epoxy tanning agent via facile functionalization of sucrose with silane coupling agent for sustainable leather production Open
View article: Structurally Diverse New Metabolites from Three Hadal Trench-Derived Microorganisms
Structurally Diverse New Metabolites from Three Hadal Trench-Derived Microorganisms Open
Two new tetraene lactone derivatives (1 and 2), two new α-pyrone derivatives (3 and 4), three compounds reported as natural products for the first time [an α-pyrone derivative (5), an indole-diketopiperaz…
View article: Multifunctional Mycelial Fragments: Enhancing Mechanical Strength, Water Vapor Transmission, Flame Retardancy, and Antibacterial Properties of Waterborne Polyurethane Coatings
Multifunctional Mycelial Fragments: Enhancing Mechanical Strength, Water Vapor Transmission, Flame Retardancy, and Antibacterial Properties of Waterborne Polyurethane Coatings Open
View article: Structurally Secondary Metabolites with Antimicrobial and Enzyme Inhibitory Activities from Hadal Trench-Derived Nigrocephalum Sp. Scsio41049
Structurally Secondary Metabolites with Antimicrobial and Enzyme Inhibitory Activities from Hadal Trench-Derived Nigrocephalum Sp. Scsio41049 Open
View article: Protective effect of Huanglian Pingwei San on DSS-induced ulcerative colitis in mice through amelioration of the inflammatory response and oxidative stress
Protective effect of Huanglian Pingwei San on DSS-induced ulcerative colitis in mice through amelioration of the inflammatory response and oxidative stress Open
Introduction Ulcerative colitis (UC) results in the breakdown of the mucosal barrier caused by persistent inflammation and oxidative stress. Huanglian Pingwei San (HLPWS) is a commonly prescribed traditional Chinese medicine for treating c…
View article: New 24-Membered Macrolactines from an Arctic Bacterium Bacillus amyloliquefaciens SCSIO 41392 and Their Anti-Pathogenicity Evaluation
New 24-Membered Macrolactines from an Arctic Bacterium Bacillus amyloliquefaciens SCSIO 41392 and Their Anti-Pathogenicity Evaluation Open
Three new 24-membered macrolactines, amylomacrolactines A–C (1–3), along with two known compounds 4 and 5, were isolated from the Arctic bacteria Bacillus amyloliquefaciens SCSIO 41392. The configurations of 1–3 were assigned by a combinat…
View article: Antitumor aspochalasin and antiviral benzofuran derivatives from a marine-derived fungus <i>Aspergillus</i> sp. SCSIO41032
Antitumor aspochalasin and antiviral benzofuran derivatives from a marine-derived fungus <i>Aspergillus</i> sp. SCSIO41032 Open
Chemical investigation of the EtOAc extract of a deep-sea derived fungus Aspergillus sp. SCSIO41032 resulted in the isolation of ten known compounds, including eight aspochalasins. Their structures were elucidated by using extensive…
View article: Novel Metabolites from the Marine-Derived Fungus Peniophora sp. SCSIO41203 Show Promising In Vitro Antitumor Activity as Methuosis Inducers in PC-3 Cells
Novel Metabolites from the Marine-Derived Fungus Peniophora sp. SCSIO41203 Show Promising In Vitro Antitumor Activity as Methuosis Inducers in PC-3 Cells Open
Two new cytochalasin derivatives, peniotrinins A (1) and B (2), three new citrinin derivatives, peniotrinins C–E (4, 5, 7), and one new tetramic acid derivative, peniotrinin F (12), along with nine structurally related known compounds, wer…
View article: Manufacturing of isocyanate-based oligomeric dyes with high coloring capabilities: synthesis and application in the dyeing of organic chrome-free leather
Manufacturing of isocyanate-based oligomeric dyes with high coloring capabilities: synthesis and application in the dyeing of organic chrome-free leather Open
View article: Secondary Metabolites from the Coral-Derived Fungus Aspergillus austwickii SCSIO41227 with Pancreatic Lipase and Neuraminidase Inhibitory Activities
Secondary Metabolites from the Coral-Derived Fungus Aspergillus austwickii SCSIO41227 with Pancreatic Lipase and Neuraminidase Inhibitory Activities Open
The coral-derived fungus Aspergillus austwickii SCSIO41227 from Beibu Gulf yielded four previously uncharacterized compounds, namely asperpentenones B–E (1–4), along with twelve known compounds (5–16). Their structures were elucidated usin…
View article: Cytotoxic phenazine and antiallergic phenoxazine alkaloids from an arctic Nocardiopsis dassonvillei SCSIO 502F
Cytotoxic phenazine and antiallergic phenoxazine alkaloids from an arctic Nocardiopsis dassonvillei SCSIO 502F Open
Microbes well-adapted to the Arctic Ocean are promising for producing novel compounds, due to their fancy strategies for adaptation and being under-investigated. Two new phenazine alkaloids ( 1 and 2 ) and one new phenoxazine ( 3 ) were is…
View article: Bisabolane-type sesquiterpenoids and bacillibactin from the marine-derived fungus <i>Aspergillus sydowii</i> SCSIO 41041 and their enzyme inhibiting activity
Bisabolane-type sesquiterpenoids and bacillibactin from the marine-derived fungus <i>Aspergillus sydowii</i> SCSIO 41041 and their enzyme inhibiting activity Open
Twelve compounds, including eleven bisabolane-type sesquiterpenoids (1 − 11), and one bacillibactin (12) were identified from marine-derived fungus Aspergillus sydowii SCSIO 41041 isolated from Creseis acicul…
View article: New Fusarin Derivatives from the Marine Algicolous Fungus Penicillium steckii SCSIO41040
New Fusarin Derivatives from the Marine Algicolous Fungus Penicillium steckii SCSIO41040 Open
Five new fusarin derivatives, steckfusarins A–E (1–5), and two known natural products (6, 7), were isolated and identified from the marine algicolous fungus Penicillium steckii SCSIO 41040. The new compounds, including absolute configurati…
View article: Design, Synthesis, and Anticancer Activity of Novel 3,6-Diunsaturated 2,5-Diketopiperazines
Design, Synthesis, and Anticancer Activity of Novel 3,6-Diunsaturated 2,5-Diketopiperazines Open
Based on the marine natural products piperafizine B, XR334, and our previously reported compound 4m, fourteen novel 3,6-diunsaturated 2,5-diketopiperazine (2,5-DKP) derivatives (1, 2, 4–6, 8–16), together with two known ones (3 and 7), wer…
View article: Novel Biomass-Based Polymeric Dyes: Preparation and Performance Assessment in the Dyeing of Biomass-Derived Aldehyde-Tanned Leather
Novel Biomass-Based Polymeric Dyes: Preparation and Performance Assessment in the Dyeing of Biomass-Derived Aldehyde-Tanned Leather Open
High-performance chrome-free leather production is currently one of the most concerning needs to warrant the sustainable development of the leather industry due to the serious chrome pollution. Driven by these research challenges, this wor…
View article: Hydrothermal conversion of biomass to fuels, chemicals and materials: A review holistically connecting product properties and marketable applications
Hydrothermal conversion of biomass to fuels, chemicals and materials: A review holistically connecting product properties and marketable applications Open
View article: Design, Synthesis and Anticancer Activity of Novel 3,6-Diunsaturated 2,5-Diketopiperazines
Design, Synthesis and Anticancer Activity of Novel 3,6-Diunsaturated 2,5-Diketopiperazines Open
Based on the marine natural products piperafizine B, X334 and our previously reported compound 4m, fourteen novel 3,6-diunsaturated 2,5-diketopiperazine (2,5-DPK) derivatives (1-2, 4-6, 8-16), together with two known ones (3 and 7), were d…
View article: Liver Protection of a Low-Polarity Fraction from Ficus pandurata Hance, Prepared by Supercritical CO2 Fluid Extraction, on CCl4-Induced Acute Liver Injury in Mice via Inhibiting Apoptosis and Ferroptosis Mediated by Strengthened Antioxidation
Liver Protection of a Low-Polarity Fraction from Ficus pandurata Hance, Prepared by Supercritical CO2 Fluid Extraction, on CCl4-Induced Acute Liver Injury in Mice via Inhibiting Apoptosis and Ferroptosis Mediated by Strengthened Antioxidation Open
Ficus pandurata Hance (FPH) is a Chinese herbal medicine widely used for health care. This study was designed to investigate the alleviation efficacy of the low-polarity ingredients of FPH (FPHLP), prepared by supercritical CO2 fluid extra…
View article: CCDC 2205154: Experimental Crystal Structure Determination
CCDC 2205154: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2205156: Experimental Crystal Structure Determination
CCDC 2205156: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2205153: Experimental Crystal Structure Determination
CCDC 2205153: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Providing Natural Organic Pigments with Excellent Tanning Capabilities: A Novel “One-Pot” Tanning–Dyeing Integration Strategy for Sustainable Leather Manufacturing
Providing Natural Organic Pigments with Excellent Tanning Capabilities: A Novel “One-Pot” Tanning–Dyeing Integration Strategy for Sustainable Leather Manufacturing Open
8 figures.-- © 2022. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
View article: Secondary Metabolites from Coral-Associated Fungi: Source, Chemistry and Bioactivities
Secondary Metabolites from Coral-Associated Fungi: Source, Chemistry and Bioactivities Open
Our study of the secondary metabolites of coral-associated fungi produced a valuable and extra-large chemical database. Many of them exhibit strong biological activity and can be used for promising drug lead compounds. Serving as an epitom…
View article: The Role of Mental Adjustment in Mediating Post-Traumatic Stress Disorder Symptoms and Social Support in Chinese Ovarian Cancer Patients: A Cross-Sectional Study
The Role of Mental Adjustment in Mediating Post-Traumatic Stress Disorder Symptoms and Social Support in Chinese Ovarian Cancer Patients: A Cross-Sectional Study Open
PTSD symptoms in OC patients should be paid attention to. Social support and mental adjustment were positive resources associated with PTSD symptoms. Moreover, mental adjustment could mediate the relation between social support and PTSD sy…
View article: Anti-inflammatory alkaloids from the cold-seep-derived fungus Talaromyces helicus SCSIO41311
Anti-inflammatory alkaloids from the cold-seep-derived fungus Talaromyces helicus SCSIO41311 Open
View article: Deep-Sea Natural Products from Extreme Environments: Cold Seeps and Hydrothermal Vents
Deep-Sea Natural Products from Extreme Environments: Cold Seeps and Hydrothermal Vents Open
The deep sea has been proven to be a great treasure for structurally unique and biologically active natural products in the last two decades. Cold seeps and hydrothermal vents, as typical representatives of deep-sea extreme environments, h…
View article: Investigation of tool flank wear effect on system stability prediction in milling of Ti-6AI-4V thin-walled workpiece
Investigation of tool flank wear effect on system stability prediction in milling of Ti-6AI-4V thin-walled workpiece Open
Excessive tool wear can shorten tool life and cause low machining surface quality and efficiency in milling of Ti-6AI-4V thin-walled workpieces. To overcome the effect of time-varying tool flank wear on system stability prediction ignored …
View article: Dynamic characteristics reconfiguration of fixture-workpiece system for vibration suppression in milling of thin-walled workpieces based on MR damping fixture
Dynamic characteristics reconfiguration of fixture-workpiece system for vibration suppression in milling of thin-walled workpieces based on MR damping fixture Open
Milling of the low rigidity and large deformation thin-walled workpiece is a critical challenging task due to the obvious machining vibration, which greatly affects the machining accuracy, surface quality of the final part. Compared with t…